المؤلفون: Ofelia Rivera Sasso, Caleb Carreño Gallardo, David Martin Soto Castillo, Omar Farid Ojeda Farias, Martin Bojorquez Carrillo, Carolina Prieto Gomez, Jose Martin Herrera Ramirez

المصدر: Clean Technologies, Vol 6, Iss 2, Pp 814-825 (2024)

مصطلحات موضوعية: waste valorization, alternative fuels, carbon emissions, clinker production, Environmental technology. Sanitary engineering, TD1-1066, Environmental engineering, TA170-171

الوصف: The cement industry contributes around 7% of global anthropogenic carbon dioxide emissions, mainly from the combustion of fuels and limestone decomposition during clinker production. Using alternative fuels derived from wastes is a key strategy to reduce these emissions. However, alternative fuels vary in composition and heating value, so selecting appropriate ones is crucial to maintain clinker quality and manufacturing processes while minimizing environmental impact. This study evaluated various biomass and industrial wastes as potential alternative fuels, characterizing them based on proximate analysis, elemental and oxide composition, lower heating value, and bulk density. Sawdust, pecan nutshell, industrial hose waste, and plastic waste emerged as viable options as they met the suggested thresholds for heating value, chloride, moisture, and ash content. Industrial hose waste and plastic waste were most favorable with the highest heating values while meeting all the criteria. Conversely, wind blade waste, tire-derived fuel, and automotive shredder residue did not meet all the recommended criteria. Therefore, blending them with alternative and fossil fuels is necessary to preserve clinker quality and facilitate combustion. The findings of this research will serve as the basis for developing a computational model to optimize the blending of alternative fuels with fossil fuels for cement production.

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2571-8797/6/2/42; https://doaj.org/toc/2571-8797

URL الوصول: https://doaj.org/article/f6113fd436884a27a5e44380b14a7c1f

المؤلفون: Beatriz Barberá Carbonell, Tobias Zingg, Maurice Matter, Gaëtan-Romain Joliat, David Martin, Manuel Pascual, Nicolas Demartines, Dela Golshayan, Luis Cano, Ismail Labgaa

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)

مصطلحات موضوعية: Complications, Prediction, Biomarkers, Transplant, Outcomes, Medicine, Science

الوصف: Abstract Kidney transplantation (KT) is associated with a substantial risk of postoperative complications (POC) for which performant predictors are lacking. Data showed that a perioperative gain of weight (ΔWeight) was associated with higher risk of POC, but it remains unexplored in KT. This retrospective study aimed to investigate the association between ΔWeight and POC after KT. ΔWeight was calculated on postoperative day (POD) 2. POC were graded according to the Dindo-Clavien classification. Primary endpoint was overall POC. A total of 242 patients were included and 174 (71.9%) complications were reported. Patients showed a rapid gain of weight after KT. Mean ΔWeight was 7.83 kg (± 3.20) compared to 5.3 kg (± 3.56) in patients with and without complication, respectively (p = 0.0005). ΔWeight showed an accuracy of 0.74 for overall POC. A cut-off of 8.5 kg was determined. ΔWeight ≥ 8.5 kg was identified as an independent predictor of overall POC on multivariable analysis (OR 2.04; 95% CI 1.08–3.84; p = 0.025). ΔWeight ≥ 8.5 kg appeared as an independent predictor of POC after KT. These results stress the need to monitor weight in KT and to further investigate this surrogate with future studies assessing its clinical relevance.

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/c940b199f6494a588c9615b3e3845131

المؤلفون: Sonja Harkener, Ekkehart Jenetzky, Rüdiger Rupp, Jennifer Dell, Christoph Engel, Maximilian Ferry von Bargen, Robert Finger, Maximilian Glienke, Carsten Heinz, Patrick Jersch, David Martin, Rita Schmutzler, Martin Schönthaler, Barbara Suwelack, Jeannine Wegner, Jürgen Stausberg

المصدر: BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-9 (2024)

مصطلحات موضوعية: Data element, Health care, Health services research, Metadata, Registry, Computer applications to medicine. Medical informatics, R858-859.7

الوصف: Abstract Background The selection of data elements is a decisive task within the development of a health registry. Having the right metadata is crucial for answering the particular research questions. Furthermore, the set of data elements determines the registries’ readiness of interoperability and data reusability to a major extent. Six health registries shared and published their metadata within a German funding initiative. As one step in the direction of a common set of data elements, a selection of those metadata was evaluated with regard to their appropriateness for a broader usage. Methods Each registry was asked to contribute a 10%-selection of their data elements to an evaluation sample. The survey was set up with the online survey tool „LimeSurvey Cloud”. The registries and an accompanying project participated in the survey with one vote for each project. The data elements were offered in content groups along with the question of whether the data element is appropriate for health registries on a broader scale. The question could be answered using a Likert scale with five options. Furthermore, “no answer” was allowed. The level of agreement was assessed using weighted Cohen’s kappa and Kendall’s coefficient of concordance. Results The evaluation sample consisted of 269 data elements. With a grade of “perhaps recommendable” or higher in the mean, 169 data elements were selected. These data elements belong preferably to groups’ demography, education/occupation, medication, and nutrition. Half of the registries lost significance compared with their percentage of data elements in the evaluation sample, one remained stable. The level of concordance was adequate. Conclusions The survey revealed a set of 169 data elements recommended for health registries. When developing a registry, this set could be valuable help in selecting the metadata appropriate to answer the registry’s research questions. However, due to the high specificity of research questions, data elements beyond this set will be needed to cover the whole range of interests of a register. A broader discussion and subsequent surveys are needed to establish a common set of data elements on an international scale.

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1472-6947

URL الوصول: https://doaj.org/article/cdc64638551f45169681e1505e1488df

المؤلفون: Britt Schoenrock, Paul E. Muckelt, Maria Hastermann, Kirsten Albracht, Robert MacGregor, David Martin, Hans-Christian Gunga, Michele Salanova, Maria J. Stokes, Martin B. Warner, Dieter Blottner

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Medicine, Science

الوصف: Abstract Muscle function is compromised by gravitational unloading in space affecting overall musculoskeletal health. Astronauts perform daily exercise programmes to mitigate these effects but knowing which muscles to target would optimise effectiveness. Accurate inflight assessment to inform exercise programmes is critical due to lack of technologies suitable for spaceflight. Changes in mechanical properties indicate muscle health status and can be measured rapidly and non-invasively using novel technology. A hand-held MyotonPRO device enabled monitoring of muscle health for the first time in spaceflight (> 180 days). Greater/maintained stiffness indicated countermeasures were effective. Tissue stiffness was preserved in the majority of muscles (neck, shoulder, back, thigh) but Tibialis Anterior (foot lever muscle) stiffness decreased inflight vs. preflight (p

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/97be173728144a41a218ead6e223f88c

المؤلفون: Greta Guglielmetti, Stephan Baumgartner, Claudia Scherr, David Martin, Alexander L. Tournier

المصدر: Frontiers in Physiology, Vol 15 (2024)

مصطلحات موضوعية: chronobiology, mistletoe, metabolomic fingerprinting, pattern formation, image analysis, medicinal plants, Physiology, QP1-981

الوصف: Introduction: European mistletoe (Viscum album L.) has been gaining increasing interest in the field of oncology as a clinically relevant adjunctive treatment in many forms of cancer. In the field of phytopharmacology, harvesting time is pivotal. In the last century, a form of metabolomic fingerprinting based on pattern formation was proposed as a way to determine optimal harvesting times to ensure high quality of mistletoe as raw material for pharmaceutical use. In order to further evaluate the information obtained with this metabolomic fingerprinting method, we analysed a large time series of previously undigitised daily mistletoe chromatograms dating back to the 1950s.Methods: These chromatograms were scanned and evaluated using computerized image analysis, resulting in 12 descriptors for each individual chromatogram. We performed a statistical analysis of the data obtained, investigating statistical distributions, cross-correlations and time self-correlations.Results: The analysed dataset spanning about 27 years, contains 19,037 evaluable chromatograms in daily resolution. Based on the distribution and cross-correlation analyses, the 12 descriptors could be clustered into six independent groups describing different aspects of the chromatograms. One descriptor was found to mirror the annual rhythm being well correlated with temperature and a phase shift of 10 days. The time self-correlation analysis showed that most other descriptors had a characteristic self-correlation of ∼50 days, which points to further infradian rhythms (i.e., more than 24 h).Discussion: To our knowledge, this dataset is the largest of its type. The combination of this form of metabolomic fingerprinting with the proposed computer analysis seems to be a promising tool to characterise biological variations of mistletoe. Additional research is underway to further analyse the different rhythms present in this dataset.

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2024.1396212/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/76bcf5ed8f844cb3b6d227399baa501c

المؤلفون: Daniela Strelchuk, Nicola Wiles, Katrina Turner, Catherine Derrick, David Martin, Jonathan Davies, Stan Zammit

المصدر: BJPsych Open, Vol 10 (2024)

مصطلحات موضوعية: EMDR, ARMS, psychosis, prevention, feasibility study, Psychiatry, RC435-571

الوصف: Background Trauma plays an important role in the development of psychosis, but no studies have investigated whether a trauma-focused therapy could prevent psychosis. Aims This study aimed to establish whether it would be feasible to conduct a multicentre randomised controlled trial (RCT) to prevent psychosis in people with an at-risk mental state (ARMS), using eye-movement desensitisation and reprocessing therapy (EMDR). Method This started as a mixed-method randomised study comparing EMDR to treatment as usual but, as a result of low participant recruitment, was changed to a single-arm feasibility study. The proposed primary outcome for an RCT was transition to psychosis at 12-month follow-up. Data on secondary outcomes were also collected. Qualitative interviews were conducted with patients and therapists. Results Fourteen participants were recruited from the Early Intervention teams. Most people who expressed an interest in taking part attended an assessment to determine eligibility. All those eligible consented to take part. A total of 64% (7 of 11) of participants who were offered EMDR were followed up at 12 months. Of the 11 participants offered EMDR, one (11%, 95% CI: 0.2%, 48%) transitioned to psychosis. Nine patients and three therapists were interviewed. Participants who completed therapy (n = 4; mean 10.5 sessions) found EMDR helpful, but those who discontinued (n = 6; mean 5.2 sessions) said it had not benefitted them overall. Therapists said EMDR could be effective, although not for all patients. Conclusions Future studies recruiting people with an ARMS to an RCT may need to extend recruitment beyond Early Intervention teams. Although some individuals found EMDR helpful, reasons for discontinuing need to be addressed in future studies.

وصف الملف: electronic resource

Relation: https://www.cambridge.org/core/product/identifier/S2056472424000577/type/journal_article; https://doaj.org/toc/2056-4724

URL الوصول: https://doaj.org/article/97610a7ba95043598b15db8e3e4df6b6

المؤلفون: Sandra Roger, Carmen Botella-Mascarell, David Martin-Sacristan, David Garcia-Roger, Jose F. Monserrat, Tommy Svensson

المصدر: IEEE Open Journal of Vehicular Technology, Vol 5, Pp 459-472 (2024)

مصطلحات موضوعية: 6G, beyond 5G, ITS, mobile communications, SDGs, Sustainability, Transportation engineering, TA1001-1280, Transportation and communications, HE1-9990

الوصف: The concept of sustainability has been recently extended to cover economic and social factors besides the traditional environmental ones. This paper reflects on the potential of mobile communication standards towards achieving sustainable mobility, with focus on vehicular communications and use cases in smart cities scenarios. In this context, intelligent transportation systems, including connected and autonomous vehicles, will be key for developing affordable and sustainable infrastructures and services. We start by identifying three current technology trends, namely, towards climate neutral; cloudification and edge computing; and Big Data and artificial intelligence, and then we examine their capability to enable sustainable Vehicle-to-Everything (V2X) communication systems in beyond 5G and 6G networks. In the second part of the paper, a set of selected use case categories involving connected and autonomous vehicles is presented, showcasing the potential impact of the selected technology trends. Finally, a review of the estimates of the quantitative savings that could be achieved in environmental-related parameters such as energy/fuel consumption and greenhouse gas emissions is provided.

وصف الملف: electronic resource

Relation: https://ieeexplore.ieee.org/document/10465596/; https://doaj.org/toc/2644-1330

URL الوصول: https://doaj.org/article/b166349ba9da4ff2aadbf79e9ddd7c7a

المؤلفون: Piero Alberti, David Martin, Georgios Gemenetzis, Rowan Parks

المصدر: Laparoscopic, Endoscopic and Robotic Surgery, Vol 6, Iss 3, Pp 83-90 (2023)

مصطلحات موضوعية: Pancreatic neuroendocrine neoplasms, Non-functional pancreatic neuroendocrine tumours, Functional pancreatic neuroendocrine tumours, Lymphadenectomy, Minimally invasive surgery, Pancreas preserving techniques, Surgery, RD1-811

الوصف: Pancreatic neuroendocrine neoplasms are a rare and complex group of neoplastic lesions that develop from pancreatic islet cells. Their incidence has dramatically increased during the last two decades. Due to its complex nature and pathophysiological behaviour, surgical management continues to evolve. Surgery remains the cornerstone of treatment for most non-functional and functional pancreatic neuroendocrine tumours, while lymphadenectomy remains a controversial subject. Different techniques, such as pancreas-preserving and minimally invasive approaches, continue to evolve and offer the same overall outcomes as open surgery. This comprehensive review describes in detail the current and most up-to-date classification and staging of pancreatic neuroendocrine tumours, explores the rationale for non-surgical and surgical management, and focuses on surgical treatment and more specifically, on minimally invasive approaches.

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468900923000397; https://doaj.org/toc/2468-9009

URL الوصول: https://doaj.org/article/e1cc76ff108d451ca898c1d213826b25

المؤلفون: Jonas Manschel, Jan Porthun, Ulrike Winkler, Jean Marie A T Beuckels, David Martin

المصدر: JMIR Human Factors, Vol 11, p e45302 (2024)

مصطلحات موضوعية: Medical technology, R855-855.5

الوصف: BackgroundThere are no uniform regulations for the osteopathic profession in Europe. It is subject to country-specific regulations defining who shall be allowed to practice osteopathy and which qualification shall be required. In recent years, legal regulations have been established in several European countries for the profession of osteopathy; however, these are also still pending for Austria. Currently, physiotherapists and physicians with osteopathic training are practicing osteopathy in Austria. ObjectiveThis study aims to examine the characteristics, challenges, and opportunities of osteopaths in Austria. MethodsGuideline-based interviews with osteopaths (N=10) were conducted. The different research questions were examined using a qualitative content analysis. ResultsThe study provided a differentiated insight into the professional situation of osteopaths in Austria. The most important result was that all interviewees unanimously supported a legal regulation of their profession. However, owing to their different professional self-image—on the one hand, individuals working on a structural basis, and, on the other hand, individuals working on a cranial or biodynamic basis—they were able to imagine a uniform professional regulation only to a limited extent. Additional topics for the interviewed osteopaths in Austria were the quality assurance of training and the urgent need for scientific research. Furthermore, the study also dealt with the influence of the COVID-19 pandemic on daily practice and on education and training in osteopathy. ConclusionsThis study is a pioneering study with regard to systematic basic research on osteopathy in Austria. The obtained results and the newly acquired research questions not only have the potential to serve as a basis for further studies but also provide insight into the working and professional situation of osteopaths in Austria for universities, schools, professional associations, politics, and—last but not least—all interested parties. International Registered Report Identifier (IRRID)RR2-10.2196/15399

وصف الملف: electronic resource

Relation: https://humanfactors.jmir.org/2024/1/e45302; https://doaj.org/toc/2292-9495

URL الوصول: https://doaj.org/article/4e9cc497a00c4b23bf6895a4648af451

المؤلفون: Jose Aguilera, Erika Hutt, Ruth Madden, Mohamed Kanj, Walid Saliba, John Rickard, Jakub Sroubek, Thomas Callahan, Mina Chung, Brian Baranowski, David Martin, Thomas Dresing, Oussama M. Wazni, Ayman Hussein, Daniel Cantillon, Divyang Patel, Shady Nakhla, Tyler Taigen

المصدر: Heliyon, Vol 9, Iss 11, Pp e22178- (2023)

مصطلحات موضوعية: Atrial fibrillation, Catheter ablation, Pulmonary vein isolation, Same day discharge, Patients outcome, Science (General), Q1-390, Social sciences (General), H1-99

الوصف: Background: Atrial fibrillation (AF) catheter ablation has become an increasingly effective and safe strategy for the management of AF. With increased safety of catheter ablation, same-day discharge (SDD) is a potential way to minimize health care resource utilization and improve patient experience. Objective: To evaluate the safety and patient satisfaction of SDD after contemporary AF ablation. Methods: Consecutive patient undergoing AF ablation at our institution between 1/2020 and 10/2021 were enrolled in registry for clinical, quality, procedural and outcomes data. Patients were considered for SDD per physician discretion and patients’ preference based upon clinical evaluation. Adjudicated ninety-day major complications, thirty-day adverse events, and thirty-day re-admissions were collected in a prospective registry for all patients. Results: A total of 2142 consecutive patients underwent elective AF ablation during the study period. After excluding cases with missing data, 1830 patients were included in the analysis. Of those, 350 (19 %) patients were discharged the same day (SDD group) and 1480 (81 %) stayed overnight. Patients in the SDD group compared to overnight stay group were younger, more likely to be male, White patients, lower CHA2DS2-VASc score and to be on lower rates of warfarin as an anticoagulation strategy. After propensity score matching, SDD was associated with lower rate of major complications and higher patient satisfaction. The majority of life-treating complications occurred interprocedurally or within 6 h of procedure termination. Conclusion: The present study demonstrated that SDD after contemporary AF ablation is feasible, safe and associated with higher patient satisfaction using a proposed SDD pathway and criteria.

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844023093866; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/456e8532994a4a6791c5c40fae07c977