لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Hongjaisee, Sayamon, Doungjinda, Natteewan, Khamduang, Woottichai, Carraway, Tanawan Samleerat, Wipasa, Jiraprapa, Debes, Jose D., Supparatpinyo, Khuanchai

المصدر: In International Journal of Infectious Diseases January 2021 102:440-445

المؤلفون: Siyu Fu, Karim, Dhamina, Prieto, Jhon, Balderramo, Domingo, Diaz Ferrer, Javier, Mattos, Angelo Z., Arrese, Marco, Carrera, Enrique, Oliveira, Jeffrey, Debes, Jose D., Boonstra, Andre

المصدر: Annals of Hepatology: Official Journal of the Mexican Association of Hepatology; Mar/Apr2024, Vol. 29 Issue 2, p1-5, 5p

مصطلحات موضوعية: HEPATOCELLULAR carcinoma, LATIN Americans, HEPATIC fibrosis, LIVER diseases, EUROPEANS

مصطلحات جغرافية: EUROPE

مستخلص: Introduction and Objectives: Tolloid like protein 1 (TLL1) rs17047200 has been reported to be associated with HCC development and liver fibrosis. However, to our knowledge, no studies have been performed on Latin Americans and comparative differences between TLL1 rs17047200 in HCC patients from Latin America and Europe are undefined. Materials and Methods: Cross-sectional analysis was performed on Latin American and European individuals. We analyzed TLL1 rs17047200 on DNA from 1194 individuals, including 420 patients with HCC (86.0 % cirrhotics) and 774 without HCC (65.9 % cirrhotics). Results: TLL1 rs17047200 genotype AT/TT was not associated with HCC development in Latin Americans (OR: 0.699, 95 %CI 0.456-1.072, p = 0.101) or Europeans (OR: 0.736, 95 %CI 0.447-1.211, p = 0.228). TLL1 AT/TT was not correlated with fibrosis stages among metabolic dysfunction-associated steatotic liver disease (MASLD) patients from Latin America (OR: 0.975, 95 %CI 0.496-1.918, p = 0.941). Among Europeans, alcohol-related HCC had lower TLL1 AT/TT frequencies than cirrhosis (18.3 % versus 42.3 %, OR: 0.273, 95 %CI 0.096-0.773, p = 0.015). Conclusions: We found no evidence that the TLL1 rs17047200 AT/TT genotype is a risk factor for HCC development in Latin Americans or Europeans. A larger study integrating ethnic and etiology backgrounds is needed to determine the importance of the TLL1 SNP in HCC development. [ABSTRACT FROM AUTHOR]

: Copyright of Annals of Hepatology: Official Journal of the Mexican Association of Hepatology is the property of Fundacion Clinica Medica Sur and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Powell, Jesse G, Goble, Spencer R, Debes, Jose D

المصدر: Journal of Infectious Diseases; 2/15/2024, Vol. 229 Issue 2, p341-345, 5p

مصطلحات موضوعية: HEPATITIS B, BOOSTER vaccines, HEPATITIS C, HEPATITIS C virus, HEPATITIS B virus

مستخلص: Background Patients with chronic hepatitis C virus (HCV) do not respond to hepatitis B virus (HBV) vaccination as efficiently as the general population. We assessed if revaccination after HCV treatment resulted in improved response. Methods Previous HBV vaccine nonresponders were prospectively recruited for revaccination after HCV eradication. Hepatitis B surface antibody (HBsAb) testing was performed 1 month after series completion. Results Follow-up HBsAb testing was performed in 31 of 34 enrolled patients with 21 (67.7%) reactive results. There were no significant differences in HBsAb reactivity based on age, sex, race, or advanced fibrosis presence. Conclusions HBV vaccine nonresponders should be considered for revaccination following HCV cure. [ABSTRACT FROM AUTHOR]

: Copyright of Journal of Infectious Diseases is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

المؤلفون: Frassone, Natalia E., Ford, James S., Villalon, Diana, Barnes, Andrés, Debes, Jose D., Marianelli, Leonardo G.

المصدر: In Wilderness & Environmental Medicine September 2019 30(3):274-280

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.