المؤلفون: Li J; Division of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, China.; Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, China.; NHC Key Laboratory of Organ Transplantation, Ministry of Health, Wuhan, China., Fang J; Division of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, China.; Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, China.; NHC Key Laboratory of Organ Transplantation, Ministry of Health, Wuhan, China., Liu Y; Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, China. yani.liu@tjh.tjmu.edu.cn., Wei X; Division of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave., Wuhan, 430030, China. xiangwei@tjh.tjmu.edu.cn.; Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, China. xiangwei@tjh.tjmu.edu.cn.; NHC Key Laboratory of Organ Transplantation, Ministry of Health, Wuhan, China. xiangwei@tjh.tjmu.edu.cn.

المصدر: Clinical research in cardiology : official journal of the German Cardiac Society [Clin Res Cardiol] 2024 May; Vol. 113 (5), pp. 680-693. Date of Electronic Publication: 2023 Nov 20.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Country of Publication: Germany NLM ID: 101264123 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-0692 (Electronic) Linking ISSN: 18610684 NLM ISO Abbreviation: Clin Res Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy* , Cardiomyopathy, Hypertrophic*/diagnosis, Humans ; Echocardiography/methods

مستخلص: Since the first description of apical hypertrophic cardiomyopathy (ApHCM) in 1976, contrasting information from all over the world has emerged regarding the natural history of the disease. However, the recommended guidelines on hypertrophic cardiomyopathy (HCM) pay a cursory reference to ApHCM, without ApHCM-specific recommendations to guide the diagnosis and management. In addition, cardiologists may not be aware of certain aspects that are specific to this disease subtype, and a robust understanding of specific disease features can facilitate recognition and timely diagnosis. Therefore, the review covers the incidence, pathogenesis, and characteristics of ApHCM and imaging methods. Echocardiography and cardiovascular magnetic resonance imaging (CMR) are the most commonly used imaging methods. Moreover, this review presents the management strategies of this heterogeneous clinical entity. In this review, we introduce a novel transapical beating-heart septal myectomy procedure for ApHCM patients with a promising short-time result.
(© 2023. The Author(s).)

المؤلفون: Yang Y; Department of Radiology, The First Affiliated Hospital of Guangxi Medical University.; Department of Radiology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning., Lu M; Department of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Beijing, China., Guan X; Department of Radiology, The First Affiliated Hospital of Guangxi Medical University., Zhao S; Department of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Beijing, China., Long L; Department of Radiology, The First Affiliated Hospital of Guangxi Medical University.

المصدر: Journal of thoracic imaging [J Thorac Imaging] 2024 May 01; Vol. 39 (3), pp. 157-164. Date of Electronic Publication: 2023 Jun 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8606160 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-0237 (Electronic) Linking ISSN: 08835993 NLM ISO Abbreviation: J Thorac Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy* , Cardiomyopathy, Hypertrophic*/complications , Cardiomyopathy, Hypertrophic*/diagnostic imaging, Humans ; Retrospective Studies ; Magnetic Resonance Imaging, Cine/methods ; Magnetic Resonance Imaging/methods ; Heart Atria/diagnostic imaging ; Magnetic Resonance Spectroscopy

مستخلص: Purpose: To evaluate the left atrial (LA) function in participants with apical hypertrophic cardiomyopathy (AHCM) by cardiovascular magnetic resonance feature tracking (CMR-FT).
Materials and Methods: Thirty typical AHCM (TAHCM) patients, 23 subclinical AHCM (SAHCM) patients and 32 normal healthy volunteers who underwent CMR exam were retrospectively analyzed. LA reservoir, conduit, and contractile function were quantified by volumetric and CMR-FT derived strain and strain rate (SR) parameters from 2-chamber and 4-chamber cine imaging.
Results: Compared with healthy participants, both TAHCM and SAHCM patients had impaired LA reservoir function (total strain [%]: TAHCM 31.3±12.2, SAHCM 31.8±12.3, controls 40.4±10.7, P <0.01; total SR [/s]: TAHCM 1.1±0.4, SAHCM 1.1±0.5, controls 1.4 ± 0.4, P <0.01) and conduit function (passive strain [%]: TAHCM 14.4±7.6, SAHCM 16.4±8.8, controls 23.3±8.1, P <0.01; passive SR [/s]: TAHCM -0.5±0.3, SAHCM -0.6±0.3, controls -1.0±0.4, P <0.01). Regarding contraction function, although TAHCM and SAHCM patients had preserved active emptying fraction and strain (all P >0.05), patients with TAHCM had the lowest active SR value among the 3 groups ( P= 0.03). LA reservoir and conduit strain were both significantly associated with left ventricular mass index and maximal wall thickness (all P <0.05). A moderate correlation between LA passive SR and left ventricular cardiac index ( P <0.01).
Conclusions: The LA reservoir and conduit function are predominately impaired and appeared in both SAHCM and TAHCM patients.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)

المؤلفون: Milaras N; Cardiology Department, General Hospital of Athens Hippokrateion, Greece. Electronic address: nikiasmilaras@gmail.com., Dourvas P; Cardiology Department, General Hospital of Athens Hippokrateion, Greece., Danelatos C; Cardiology Department, General Hospital of Athens Hippokrateion, Greece., Archontakis S; Cardiology Department, General Hospital of Athens Hippokrateion, Greece., Sideris S; Cardiology Department, General Hospital of Athens Hippokrateion, Greece.

المصدر: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology [Rev Port Cardiol] 2024 Mar; Vol. 43 (3), pp. 141-142. Date of Electronic Publication: 2024 Jan 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lisbon Country of Publication: Portugal NLM ID: 8710716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2174-2030 (Electronic) Linking ISSN: 08702551 NLM ISO Abbreviation: Rev Port Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy*, Humans ; Defibrillators

المؤلفون: Khoury S; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Bhatia RT; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Marwaha S; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Miles C; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Kasiakogias A; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Bunce N; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Behr E; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Papadakis M; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Sharma S; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom., Tome M; Cardiovascular Clinical Academic Group, St. George's, University of London, St. George's University Hospitals NHS Foundation Trust, United Kingdom. Electronic address: mtome@sgul.ac.uk.

المصدر: International journal of cardiology [Int J Cardiol] 2023 Nov 15; Vol. 391, pp. 131265. Date of Electronic Publication: 2023 Aug 11.

نوع المنشور: Observational Study; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomyopathy, Hypertrophic*/diagnostic imaging , Cardiomyopathy, Hypertrophic*/pathology , Apical Hypertrophic Cardiomyopathy* , Hypertension*, Humans ; Male ; Female ; Retrospective Studies ; Cross-Sectional Studies ; Electrocardiography ; Arrhythmias, Cardiac ; Hypertrophy

مستخلص: Background: We investigated whether ethnicity and sex are associated with different clinical presentations and cardiovascular magnetic resonance (CMR) findings in individuals with apical hypertrophic cardiomyopathy (ApHCM).
Methods: A retrospective observational cohort study of consecutive ApHCM patients from a large tertiary referral center in the United Kingdom (UK). Demographic, clinical, 12‑lead electrocardiogram (ECG) and CMR findings were collected. Participants presented in our clinics between 2010 and 2020. 'Pure' ApHCM was defined as isolated apical hypertrophy and 'mixed' with both apical and septal hypertrophy but with the apical segments of a greater wall thickness. Deep T-wave inversion was defined as ≥5 mm in any electrocardiogram lead.
Results: A total of 150 consecutive ApHCM patients (75% men, 25% women; 37% White, 25% Black, 24% Asian and 15% of Mixed/Other ethnicity) were included. Females were diagnosed at an older age compared to men, had less prominent ECG changes, had higher left atrial area index, and were more hypertensive. Black patients had higher left ventricular mass index, more hypertension, and more of the 'mixed' type of ApHCM. The majority of hypertensive male patients showed the 'mixed' phenotype.
Conclusions: Individuals of Black ethnicity and hypertensive male patients are more likely to present with mixed apical and basal hypertrophy, whereas White, Asian and non-hypertensive male patients tend to have hypertrophy limited to the apex. Females present at an older age and are less likely to have deep T wave inversion on ECG.
Competing Interests: Declaration of Competing Interest The authors declare no competing interests.
(Copyright © 2023. Published by Elsevier B.V.)

المؤلفون: Yu SQ; Department of Magnetic Resonance, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases of China, Fuwai Hospital, Beijing 100037, China., Yang K; Department of Magnetic Resonance, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases of China, Fuwai Hospital, Beijing 100037, China., Zhao SH; Department of Magnetic Resonance, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases of China, Fuwai Hospital, Beijing 100037, China.

المصدر: Zhonghua xin xue guan bing za zhi [Zhonghua Xin Xue Guan Bing Za Zhi] 2024 Jan 24; Vol. 52 (1), pp. 79-81.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Zhonghua yi xue hui Country of Publication: China NLM ID: 7910682 Publication Model: Print Cited Medium: Print ISSN: 0253-3758 (Print) Linking ISSN: 02533758 NLM ISO Abbreviation: Zhonghua Xin Xue Guan Bing Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy* , Heart Aneurysm*/complications , Cardiomyopathy, Hypertrophic*/complications , Ventricular Outflow Obstruction*/etiology, Humans

المؤلفون: Kawakami K; Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo 060-8638, Japan., Omote K; Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo 060-8638, Japan., Tsuneta S; Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan., Nagai T; Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo 060-8638, Japan., Anzai T; Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo 060-8638, Japan.

المصدر: European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2023 Dec 21; Vol. 25 (1), pp. e57.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101573788 Publication Model: Print Cited Medium: Internet ISSN: 2047-2412 (Electronic) Linking ISSN: 20472404 NLM ISO Abbreviation: Eur Heart J Cardiovasc Imaging Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy* , Cardiomyopathy, Hypertrophic*/diagnostic imaging , Sarcoidosis*/diagnostic imaging, Humans ; Myocardium ; Biopsy ; Electrocardiography

مستخلص: Competing Interests: Conflict of interest: Nothing to disclose.

المؤلفون: Gao M; Department of Cardiology, Hebei General Hospital, Shijiazhuang, China., Zhang F, Xie Y, Li J, Hao X, Liu H, Qi X, Dang Y

المصدر: Medicine [Medicine (Baltimore)] 2023 Nov 10; Vol. 102 (45), pp. e35823.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE

مواضيع طبية MeSH: Endomyocardial Fibrosis*/diagnosis , Endomyocardial Fibrosis*/diagnostic imaging , Apical Hypertrophic Cardiomyopathy* , Cardiomyopathy, Hypertrophic*/diagnosis , Cardiomyopathy, Hypertrophic*/diagnostic imaging , Calcinosis*/complications , Calcinosis*/diagnostic imaging , Heart Failure*, Humans ; Echocardiography/methods

مستخلص: Rationale: Apical hypertrophic cardiomyopathy (ApHCM) is a phenotypic variant of hypertrophic cardiomyopathy. Endomyocardial fibrosis and endocardial calcification are especially rare in ApHCM.
Patient Concerns: The main symptoms was chest tightness, palpitation, shortness of breath, and fatigue. Echocardiography and imaging examinations found apical hypertrophy along with endocardial calcification and endomyocardial fibrosis. Abnormal structural changes led to thrombosis and made the left ventricle a flat shape resembling an "apple."
Diagnoses: The typical presentations, hypertrophic apex on echocardiography and an elevated N-terminal pro-brain natriuretic peptide level indicated the diagnosis of ApHCM and heart failure with preserved ejection fraction.
Interventions: Optimal medical therapy including the administration of ApHCM, heart failure and atrial fibrillation to improve symptoms and life quality.
Outcomes: Since discharge, the patient could perform normal daily activities and had no discomfort based on the optimal medical therapy.
Lessons: We report a ApHCM patients with unusual presentations of endomyocardial fibrosis and apical calcification. This case highlights the importance of understanding the specific pathological changes of ApHCM for treatment and prognosis.
Competing Interests: The authors have no conflicts of interest to disclose.
(Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)

المؤلفون: Rouskas P; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece., Zegkos T; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece. Electronic address: zegkosth@gmail.com., Ntelios D; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece., Gossios T; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece., Parcharidou D; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece., Papanastasiou CA; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece., Karamitsos T; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece., Vassilikos V; Third Cardiology Department, HIPPOKRATION University Hospital, Thessaloniki, Greece., Kouskouras K; Department of Radiology, University General Hospital of Thessaloniki AHEPA, Thessaloniki, Greece., Efthimiadis GK; First Cardiology Department, AHEPA University Hospital, Thessaloniki, Greece.

المصدر: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese [Hellenic J Cardiol] 2023 Sep-Oct; Vol. 73, pp. 8-15. Date of Electronic Publication: 2023 Feb 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101257381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2241-5955 (Electronic) Linking ISSN: 11099666 NLM ISO Abbreviation: Hellenic J Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Atrial Fibrillation*/complications , Atrial Fibrillation*/epidemiology , Cardiomyopathy, Hypertrophic*/complications , Cardiomyopathy, Hypertrophic*/epidemiology , Cardiomyopathy, Hypertrophic*/diagnosis , Apical Hypertrophic Cardiomyopathy*, Middle Aged ; Humans ; Retrospective Studies ; Prevalence ; Prognosis ; Risk Factors ; Death, Sudden, Cardiac ; Phenotype

مستخلص: Background: Apical hypertrophic cardiomyopathy (ApHCM) is a variant of hypertrophic cardiomyopathy (HCM) with distinct imaging and clinical characteristics. Data on the prognosis of this HCM subgroup appear conflicting. Our study aims to clarify the natural history of ApHCM and identify predictors of outcomes.
Materials and Methods: A total of 856 patients with HCM were retrospectively examined. ApHCM was defined as asymmetric left ventricular hypertrophy confined predominantly at the apex, either isolated (pure ApHCM type) or with co-existent hypertrophy of the interventricular septum (mixed ApHCM). Echocardiographic, clinical, and survival data were compared between individuals with ApHCM and non-ApHCM.
Results: A total of 143 (16.7%) patients were diagnosed with ApHCM. Compared with non-ApHCM, subjects with apical HCM were diagnosed at an older age and had better echocardiographic indices and more comorbidities at baseline. Apical aneurysms were more prevalent among the ApHCM phenotype (6.3% vs. 1.7%, p = 0.003). During a mean follow-up of 6 ± 3 years, ApHCM was characterized by lower all-cause, cardiovascular, heart failure-related mortality, and ventricular arrhythmic events compared with non-ApHCM. Multivariate analysis identified atrial fibrillation and HCM risk-sudden cardiac death (SCD) as independent predictors of the composite outcome of overall mortality and hospitalizations for cardiovascular reasons (hazard ratio [HR] 4.3, 95% confidence interval [CI] 1.9-9.5 for atrial fibrillation and HR 1.2, 95% CI 1.02-1.3 for HCM risk-SCD) in ApHCM.
Conclusions: ApHCM exhibited a lower rate of all-cause mortality and arrhythmic events in the middle-aged population of patients with HCM. Atrial fibrillation and HCM risk-sudden cardiac death were independent predictors of a composite of overall mortality and cardiovascular hospitalizations among those with ApHCM.
(Copyright © 2023 Hellenic Society of Cardiology. Published by Elsevier B.V. All rights reserved.)

المؤلفون: Zhao Y; Department of Echocardiography Cardiovascular Institute, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China., Wang H; Department of Echocardiography Cardiovascular Institute, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China., Yang K; Department of Magnetic Resonance Imaging, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beigjing 100037, China., Lin JR; Department of Echocardiography Cardiovascular Institute, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China., Quan X; Department of Echocardiography Cardiovascular Institute, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China., Qu R; Department of Echocardiography Cardiovascular Institute, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China., Zhao SH; Department of Magnetic Resonance Imaging, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beigjing 100037, China.

المصدر: Zhonghua xin xue guan bing za zhi [Zhonghua Xin Xue Guan Bing Za Zhi] 2023 Oct 24; Vol. 51 (10), pp. 1075-1079.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Zhonghua yi xue hui Country of Publication: China NLM ID: 7910682 Publication Model: Print Cited Medium: Print ISSN: 0253-3758 (Print) Linking ISSN: 02533758 NLM ISO Abbreviation: Zhonghua Xin Xue Guan Bing Za Zhi Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy* , Cardiomyopathy, Hypertrophic*/complications , Cardiomyopathy, Hypertrophic*/diagnostic imaging , Heart Aneurysm*/complications , Heart Aneurysm*/diagnostic imaging, Male ; Humans ; Female ; Retrospective Studies ; Stroke Volume ; Ventricular Function, Left ; Echocardiography

مستخلص: Objective: To explore the basic characteristics of conventional echocardiography of apical hypertrophic cardiomyopathy (ApHCM) patients complicating with left ventricular apical aneurysm (LVAA). Methods: This is a retrospective study. Patients who underwent echocardiography and cardiac magnetic resonance (CMR) and were diagnosed with ApHCM complicated with LVAA by CMR at Fuwai Hospital, Chinese Academy of Medical Sciences from August 2012 to July 2017 were enrolled. According to whether LVAA was detected by echocardiography, the enrolled patients were divided into two groups: LVAA detected by echocardiography group and LVAA not detected by echocardiography group. Clinical data of the two groups were compared to analyze the causes of missed diagnosis by echocardiography. Results: A total of 21 patients were included, of whom 67.0% (14/21) were males, aged (56.1±16.5) years. Patients with chest discomfort accounted for 81.0% (17/21), palpitation 38.1% (8/21), syncope 14.3% (3/21). ECG showed that 21 (100%) patients had ST-T changes and 18 (85.7%) had deep T-wave invertion. Echocardiography revealed ApHCM in 17 cases (81.0%) and LVAA in 7 cases (33.3%). The mean left ventricular apical aneurysm diameter was 33.0 (18.0, 37.0) mm, and left ventricular ejection fraction was (66.5±6.6) %, and left ventricular apex thickness was (21.0±6.3) mm. Left ventricular outflow tract obstruction was presented in 4 cases and middle left ventricular obstruction in 10 cases. The mean left ventricular apical aneurysm diameter of LVAA detected by echocardiography was greater than that of LVAA not detected by echocardiography (25.0 (18.0, 28.0) mm vs. 16.0 (12.3, 21.0) mm, P =0.006). Conclusions: Conventional echocardiography examination has certain limitations in the diagnosis of ApHCM. Smaller LVAA complicated with ApHCM is likely to be unrecognized by echocardiography. Clinicians should improve their understanding of this disease.

المؤلفون: Kadoya Y; Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada. YKadoya@ottawaheart.ca., Small GS; Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada., Ruddy TD; Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.

المصدر: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2023 Oct; Vol. 30 (5), pp. 2233-2239. Date of Electronic Publication: 2022 Dec 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society of Nuclear Cardiology Country of Publication: United States NLM ID: 9423534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6551 (Electronic) Linking ISSN: 10713581 NLM ISO Abbreviation: J Nucl Cardiol Subsets: MEDLINE

مواضيع طبية MeSH: Apical Hypertrophic Cardiomyopathy* , Cardiomyopathy, Hypertrophic*/diagnostic imaging , Cardiomyopathy, Hypertrophic*/surgery , Heart Transplantation*/adverse effects, Humans ; Electrocardiography