المؤلفون: Cellupica E; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Gaiassi A; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Rocchio I; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Rovelli G; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Pomarico R; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Sandrone G; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Caprini G; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Cordella P; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Cukier C; Department of Biochemistry, Selvita S.A., 30-394 Kraków, Poland., Fossati G; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Marchini M; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Bebel A; Department of Biochemistry, Selvita S.A., 30-394 Kraków, Poland., Airoldi C; Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy., Palmioli A; Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy., Stevenazzi A; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Steinkühler C; Research and Development, Italfarmaco Group, 20092 Milan, Italy., Vergani B; Research and Development, Italfarmaco Group, 20092 Milan, Italy.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 May 28; Vol. 25 (11). Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Oxadiazoles*/chemistry , Oxadiazoles*/pharmacology , Histone Deacetylase 6*/antagonists & inhibitors , Histone Deacetylase 6*/metabolism , Histone Deacetylase 6*/chemistry , Histone Deacetylase Inhibitors*/chemistry , Histone Deacetylase Inhibitors*/pharmacology, Humans ; Crystallography, X-Ray ; Kinetics ; Protein Binding ; Models, Molecular ; Structure-Activity Relationship

المؤلفون: Zhang W; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Jiao B; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Yu S; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhang C; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhang K; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Liu B; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhang X; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

المصدر: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 May; Vol. 30 (5), pp. e14745.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic*/drug effects , Histone Deacetylase Inhibitors*/pharmacology , Histone Deacetylase Inhibitors*/therapeutic use , Histone Deacetylases*/metabolism , Neuralgia*/drug therapy , Neuralgia*/metabolism, Humans

المؤلفون: Zhou AM; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, P. R. China., Wang MM; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, P. R. China., Su Y; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, P. R. China.; Department of Rheumatology and Immunology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, P. R. China., Yu ZH; Department of Rheumatology and Immunology, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, P. R. China., Liu HK; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, P. R. China., Su Z; Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing, 210023, P. R. China.

المصدر: ChemMedChem [ChemMedChem] 2023 Mar 01; Vol. 18 (5), pp. e202200614. Date of Electronic Publication: 2023 Jan 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase Inhibitors*/pharmacology , Valproic Acid*/pharmacology, Humans ; Histone Deacetylase 6 ; HeLa Cells ; Cell Line, Tumor ; Apoptosis ; Cell Death ; Autophagy ; Histone Deacetylase 1

المؤلفون: Jacinto MP; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, Maryland 21218, United States., Greenberg MM; Department of Chemistry, Johns Hopkins University, 3400 N. Charles St., Baltimore, Maryland 21218, United States.

المصدر: Biochemistry [Biochemistry] 2023 Apr 18; Vol. 62 (8), pp. 1388-1393. Date of Electronic Publication: 2023 Mar 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , Histone Deacetylase 1*/genetics , Histone Deacetylase 1*/metabolism , Histones*/metabolism, Humans ; Acetylation ; DNA/metabolism ; HeLa Cells ; Histone Deacetylase 2/genetics ; Histone Deacetylase 2/metabolism ; Peptides/metabolism ; Protein Processing, Post-Translational

المؤلفون: Herath KE; Department of Chemistry, Wayne State University, 5101 Cass Ave, Detroit, MI 48202, United States of America., Kodikara IKM; Department of Chemistry, Wayne State University, 5101 Cass Ave, Detroit, MI 48202, United States of America., Pflum MKH; Department of Chemistry, Wayne State University, 5101 Cass Ave, Detroit, MI 48202, United States of America. Electronic address: pflum@wayne.edu.

المصدر: Journal of proteomics [J Proteomics] 2023 Mar 15; Vol. 274, pp. 104807. Date of Electronic Publication: 2022 Dec 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101475056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7737 (Electronic) Linking ISSN: 18743919 NLM ISO Abbreviation: J Proteomics Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase 1*/genetics , Histone Deacetylase 1*/metabolism , Proteomics*/methods, Humans ; HEK293 Cells ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylases/genetics ; Histone Deacetylases/metabolism ; Substrate Specificity

المؤلفون: Kong SJ; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea., Nam G; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea., Boggu PR; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea., Park GM; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea., Kang JE; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea., Park HJ; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea., Jung YH; School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea. Electronic address: yhjung@skku.edu.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2023 Feb 01; Vol. 79, pp. 117154. Date of Electronic Publication: 2023 Jan 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase Inhibitors*/pharmacology , Histone Deacetylases*/metabolism, Histone Deacetylase 6 ; Hydroxamic Acids/pharmacology ; Triazoles/pharmacology ; Histone Deacetylase 1

المؤلفون: Wang K; Department of Cardiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Zhang Y, Zhou M, Du Y, Li P, Guan C, Huang Z

المصدر: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2023 Feb 01; Vol. 81 (2), pp. 150-164. Date of Electronic Publication: 2023 Feb 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Electronic Cited Medium: Internet ISSN: 1533-4023 (Electronic) Linking ISSN: 01602446 NLM ISO Abbreviation: J Cardiovasc Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase Inhibitors*/metabolism , Histone Deacetylase Inhibitors*/pharmacology , Hyperuricemia*, Animals ; Humans ; Mice ; Histone Deacetylase 6/metabolism ; Histone Deacetylase 6/pharmacology ; Human Umbilical Vein Endothelial Cells ; Inflammation/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction ; Uric Acid

المؤلفون: Sardar S; Laboratory of Drug Design and Discovery, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India., Jyotisha; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, India., Amin SA; Laboratory of Drug Design and Discovery, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India.; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India., Khatun S; Laboratory of Drug Design and Discovery, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India., Qureshi IA; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, India., Patil UK; Department of Pharmaceutical Sciences, Dr. Harisingh Gour University, Sagar, India., Jha T; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India., Gayen S; Laboratory of Drug Design and Discovery, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Jul; Vol. 42 (11), pp. 5642-5656. Date of Electronic Publication: 2023 Jun 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase 1*/antagonists & inhibitors , Histone Deacetylase 1*/chemistry , Histone Deacetylase 1*/metabolism , Histone Deacetylase Inhibitors*/chemistry , Histone Deacetylase Inhibitors*/pharmacology , Molecular Docking Simulation* , Molecular Dynamics Simulation* , Drug Discovery*/methods , Epigenesis, Genetic* , Neoplasms*/drug therapy , Neoplasms*/genetics , Neoplasms*/enzymology, Humans ; Protein Binding ; Biological Products/chemistry ; Biological Products/pharmacology ; Ligands ; Bayes Theorem ; Structure-Activity Relationship ; Binding Sites

المؤلفون: Fan W; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Zeng S; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Wang X; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Wang G; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Liao D; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Li R; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., He S; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Li W; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Huang J; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Li X; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Liu J; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China., Li N; Department of Laboratory Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, 100005, China. coco0411@126.com., Hou S; The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, Chongqing Eye Institute, Chongqing, China. sphou828@163.com.; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, 100730, China. sphou828@163.com.

المصدر: Genome biology [Genome Biol] 2024 Jun 25; Vol. 25 (1), pp. 165. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase 2*/metabolism , Histone Deacetylase 2*/genetics , Vascular Endothelial Growth Factor A*/metabolism , Histones*/metabolism , Feedback, Physiological* , Neovascularization, Physiologic*/drug effects, Humans ; Animals ; Endothelial Cells/metabolism ; Mice ; Human Umbilical Vein Endothelial Cells/metabolism ; Glycolysis ; Neovascularization, Pathologic/metabolism ; Angiogenesis

المؤلفون: Bahram Sangani N; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD, Maastricht, The Netherlands. nasim.sangani@maastrichtuniversity.nl.; GKC, Maastricht University Medical Centre, 6229 ER, Maastricht, The Netherlands. nasim.sangani@maastrichtuniversity.nl., Koetsier J; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD, Maastricht, The Netherlands.; GKC, Maastricht University Medical Centre, 6229 ER, Maastricht, The Netherlands., Mélius J; DataHub, Maastricht University & Maastricht UMC+, P. Debyelaan 15, 6229 HX, Maastricht, The Netherlands., Kutmon M; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, 6200 MD, Maastricht, The Netherlands., Ehrhart F; Department of Bioinformatics - BiGCaT, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, 6200 MD, Maastricht, The Netherlands.; Department of Psychiatry and Neuropsychology, Research Institute for Mental Health and Neuroscience (MHeNs), Maastricht University, 6200 MD, Maastricht, The Netherlands., Evelo CT; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, 6200 MD, Maastricht, The Netherlands.; Department of Bioinformatics - BiGCaT, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, 6200 MD, Maastricht, The Netherlands., Curfs LMG; GKC, Maastricht University Medical Centre, 6229 ER, Maastricht, The Netherlands., Reutelingsperger CP; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, 6200 MD, Maastricht, The Netherlands.; GKC, Maastricht University Medical Centre, 6229 ER, Maastricht, The Netherlands., Eijssen LMT; Department of Bioinformatics - BiGCaT, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, 6200 MD, Maastricht, The Netherlands.; Department of Psychiatry and Neuropsychology, Research Institute for Mental Health and Neuroscience (MHeNs), Maastricht University, 6200 MD, Maastricht, The Netherlands.

المصدر: Scientific reports [Sci Rep] 2024 Jun 25; Vol. 14 (1), pp. 14666. Date of Electronic Publication: 2024 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase 6*/metabolism , Histone Deacetylase 6*/genetics , Protein Interaction Maps*, Humans ; Nervous System Diseases/metabolism ; Nervous System Diseases/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/genetics ; Phosphorylation ; Acetylation ; Parkinson Disease/metabolism ; Parkinson Disease/genetics ; Parkinson Disease/pathology