-
1دورية أكاديمية
المؤلفون: Roberts, GemmaAff1, Aff2, IDs12350019019775_cor1, Lloyd, Jim J.Aff1, Aff2, Jefferson, Elizabeth, Kane, Joseph P. M., Durcan, Rory, Lawley, Sarah, Petrides, George S., Howe, Kim, Haq, Iftikhar, O’Brien, John T., Thomas, Alan J.
المصدر: Journal of Nuclear Cardiology. 28(5):2151-2163
-
2دورية أكاديمية
المؤلفون: Roberts, GemmaAff1, Aff2, Lloyd, James J.Aff1, Aff2, Petrides, George S., Donaghy, Paul C., Kane, Joseph P. M.Aff1, Aff3, Durcan, Rory, Lawley, Sarah, Howe, Kim, Sims, Andrew J.Aff4, Aff5, Taylor, John-Paul, O’Brien, John T.Aff1, Aff6, Thomas, Alan J.
المصدر: Annals of Nuclear Medicine. 33(6):434-443
-
3دورية أكاديمية
المؤلفون: Durcan, Rory, Roberts, Gemma, Hamilton, Calum A., Donaghy, Paul C., Howe, Kim, Colloby, Sean J., Allan, Louise M., Firbank, Michael, Lawley, Sarah, Petrides, George S., Lloyd, Jim J., Taylor, John-Paul, O'Brien, John T., Thomas, Alan J.
المصدر: Neurology; 9/19/2023, Vol. 101 Issue 12, pe1196-e1205, 10p
-
4دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
5دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
6دورية أكاديمية
المؤلفون: Roberts, Gemma, Lloyd, Jim J., Jefferson, Elizabeth, Kane, Joseph P. M., Durcan, Rory, Lawley, Sarah, Petrides, George S., Howe, Kim, Haq, Iftikhar, O’Brien, John T., Thomas, Alan J., O'Brien, John T
المصدر: Journal of Nuclear Cardiology; Oct2021, Vol. 28 Issue 5, p2151-2163, 13p
مستخلص:
Introduction: Some studies report that assessing regional 123I-cardiac MIBG uptake can aid in the diagnosis of Lewy body disease, but others report heterogeneity in healthy controls. We aimed to evaluate regional cardiac MIBG uptake patterns in healthy older adults and patients with dementia.Methods: 31 older adults with normal cognition, 15 Alzheimer's disease (AD), and 17 Dementia with Lewy bodies (DLB) patients were recruited. 5 individuals had previous myocardial infarction. Participants with sufficient cardiac uptake for regional SPECT analysis (29/31 controls, 15/15 AD, 5/17 DLB) had relative uptake pattern recorded. Controls were assessed for risk of future cardiovascular events using QRISK2, a validated online tool.Results: In controls uptake was reduced in the inferior wall (85%), apex (23%), septum (15%), and lateral wall (8%). AD and DLB showed similar patterns to controls. Lung or liver interference was present in 61% of cases. Myocardial infarction cases showed regional reductions in uptake, but normal/borderline planar uptake. In controls, there was no relationship between cardiovascular risk score and uptake pattern.Conclusions: Significant variability of regional cardiac 123I-MIBG uptake is common in cases with normal planar cardiac uptake. Heterogeneity of regional uptake appears non-specific and unlikely to aid in the diagnosis of Lewy body disease. [ABSTRACT FROM AUTHOR]: Copyright of Journal of Nuclear Cardiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
-
7دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
8دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
9دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل. -
10دورية أكاديمية
لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.