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1دورية أكاديمية
المؤلفون: Yasukazu Ogai, Ryoko Nakajima-Yamaguchi, Hirotsuna Ohashi, Kentaro Niwa, Toyoo Sakurayama, Nobuaki Morita
المصدر: Frontiers in Child and Adolescent Psychiatry, Vol 3 (2024)
مصطلحات موضوعية: child abuse, child maltreatment, risk prediction, big-data analysis, severity, Psychiatry, RC435-571, Pediatrics, RJ1-570
الوصف: IntroductionThe present study conducted a secondary data analysis of a comprehensive survey from Child Guidance Centers in Japan to identify factors that are associated with child abuse severity in infancy (0–3 years, 1,868 cases) and preschool age (4–6 years, 1,529 cases). A predictive model for abuse severity was developed.MethodsThe data originated from a nationwide survey that was conducted in April 2013, consisting of details of abuse cases, including child characteristics, abuser attributes, and family situation. Abuse severity was assessed on a five-level scale (suspected, mild, moderate, severe, and life-threatening) that was converted into a binary outcome. Logistic regression analysis was used to create a predictive model using two-thirds of the data, which was validated with the remaining third of the data.Results and discussionAs a result, in infancy, risks of severity increased with younger age of the abused child, physical abuse, neglect, witnessing domestic violence, and the involvement of Child Guidance Centers or hospitals in detection. The abuser's mental problems and cumulative child damage contributed to severity. For preschool age, similar factors applied, with additional risks that included abuse overlap and guardian separation. Cumulative abuser issues and child physical damage impacted severity. Validation yielded moderate prediction accuracy (areas under the curve: 0.703 and 0.714).
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Seinen Chow, Yoshikazu Kajigaya, Hiroaki Kurogi, Kentaro Niwa, Takuro Shibuno, Atsushi Nanami, Setuo Kiyomoto
المصدر: PLoS ONE, Vol 9, Iss 7, p e102376 (2014)
الوصف: Four long-spined sea urchin species in the genus Diadema are known to occur around the Japanese Archipelago. Three species (D. savignyi, D. setosum, and D. paucispinum) are widely distributed in the Indo-Pacific Ocean. The fourth species was detected by DNA analysis among samples originally collected as D. savignyi or D. setosum in Japan and the Marshall Islands and tentatively designated as Diadema-sp, remaining an undescribed species. We analyzed nucleotide sequences of the cytochrome oxidase I (COI) gene in the "D. savignyi-like" samples, and found all 17 individuals collected in the mainland of Japan (Sagami Bay and Kyushu) to be Diadema-sp, but all nine in the Ryukyu Archipelago (Okinawa and Ishigaki Islands) to be D. savignyi, with large nucleotide sequence difference between them (11.0%±1.7 SE). Diadema-sp and D. savignyi shared Y-shaped blue lines of iridophores along the interambulacrals, but individuals of Diadema-sp typically exhibited a conspicuous white streak at the fork of the Y-shaped blue iridophore lines, while this feature was absent in D. savignyi. Also, the central axis of the Y-shaped blue lines of iridophores was approximately twice as long as the V-component in D. savignyi whereas it was of similar length in Diadema-sp. Two parallel lines were observed to constitute the central axis of the Y-shaped blue lines in both species, but these were considerably narrower in Diadema-sp. Despite marked morphological and genetic differences, it appears that Diadema-sp has been mis-identified as D. savignyi for more than half a century.
وصف الملف: electronic resource
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المؤلفون: Motoharu Uchida, Yuka Ishihi, Satoshi Watanabe, Mutsumi Tsujino, Naoaki Tezuka, Yoshitake Takada, Kentaro Niwa
المصدر: Fisheries Science. 89:203-214
مصطلحات موضوعية: Aquatic Science
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4
المؤلفون: Kenji Niwa, Motoki Takenaka, Takeaki Saitake, Tiger Koike, Kentaro Nagata, Kentaro Niwa, Kohjiro Niwa, Sakae Mori, Keigo Kuwabara, Akane Onogi, Takuji Tanaka
المصدر: Open Journal of Pathology. 12:22-30
مصطلحات موضوعية: General Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3accc3b819383bd4c3ae01f6e64f495d
https://doi.org/10.4236/ojpathology.2022.121003 -
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المؤلفون: Yoshihiro Seto, Kentaro Niwa, Fumiyasu Okazaki, Hideto To
المصدر: European Journal of Pharmacology. 942:175519
مصطلحات موضوعية: Pharmacology
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المؤلفون: Takuji Tanaka, Motoki Takenaka, Kenji Niwa, Kentaro Niwa, Takefumi Nakagami, Kentaro Nagata, Ryuichiro Shimaoka, Nobuo Okumura
المصدر: Case Reports in Clinical Medicine. 10:108-116
مصطلحات موضوعية: Prothrombin time, Major Bleeding Event, Abdominal pain, medicine.medical_specialty, Hysterectomy, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Dysfibrinogenemia, Myoma, General Medicine, medicine.disease, Asymptomatic, Arg to His Mutation, Surgery, medicine, Fresh frozen plasma, medicine.symptom, business, Partial thromboplastin time
الوصف: Article
Case Reports in Clinical Medicine. 10: 108-116 (2021)وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285e77903a9d3d334d859dd8217e1282
https://soar-ir.repo.nii.ac.jp/records/2000572 -
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المؤلفون: Takuji Tanaka, Keigo Kuwabara, Kentaro Nagata, Kentaro Niwa, Sakae Mori, Kenji Niwa, Yoshio Yamaguchi, Motoki Takenaka, Tomomi Shiga
المصدر: Open Journal of Pathology. 11:22-31
مصطلحات موضوعية: Pathology, medicine.medical_specialty, biology, business.industry, Vimentin, medicine.disease, Carcinosarcoma, medicine, biology.protein, Carcinoma, Adenocarcinoma, Sarcoma, Chondrosarcoma, business, Fibrosarcoma, Ovarian Carcinosarcoma
الوصف: Ovarian carcinosarcoma composed of high-grade carcinoma and sarcoma is an extremely rare neoplasm and typically occurs in postmenopausal women aged over 60 years. A 73-year-old female, gravida three para three, presented to our hospital with right lower abdominal pain. Right pelvic solid tumor with ascites was detected on pelvic ultrasound examination. She underwent hysterectomy, bilateral salpingo-oophorectomy and partial omentectomy, but the tumor had invaded to the right ureter, and some fragile tumor could not be taken (sub-optimal surgery). On the imprint and ascitic cytology specimens during operation, atypical cells suggestive of adenocarcinoma and spindle atypical cells with immunocytochemically vimentin positive were found. The resected tumor was histopathologically carcinosarcoma consisted of serous adenocarcinoma, chondrosarcoma and fibrosarcoma. Immunohistochemical analysis revealed that adenocarcinoma cells were positive for AE1/AE3 and fibrosarcoma cells stained with vimentin. The final diagnosis was the right ovarian carcinosarcoma (stage pT3CNxMx). Microsatellite instability was stable and BRCA1/2 mutations could not be found in the carcinosarcoma cells. The patient was given four cycles of chemotherapy with paclitaxel, carboplatin and bevacizumab regimen, and thereafter she was treated with the ifosfamide and cisplatin because of slight elevation of serum CA125.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf68f4443eea7fba07eab6ecd84eae3d
https://doi.org/10.4236/ojpathology.2021.111003 -
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المؤلفون: Kentaro Niwa, Hiroaki Kurogi, Takuro Shibuno, Shuhei Sawayama, Yoshikazu Kajigaya, Yuka Ishihi, Ryo Orita, Seinen Chow, Wataru Teramoto, Jun Hayakawa
المصدر: NIPPON SUISAN GAKKAISHI. 86:9-19
مصطلحات موضوعية: biology, biology.animal, Zoology, Aquatic Science, biology.organism_classification, Sea urchin, Diadema setosum
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c490f8278407714d3cae5568538cfdb2
https://doi.org/10.2331/suisan.19-00015 -
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المؤلفون: Keigo Kuwabara, Kentaro Nagata, Takuji Tanaka, Motoki Takenaka, Kentaro Niwa, Kenji Niwa, Sakae Mori, Yoshio Yamaguchi
المصدر: Open Journal of Pathology. 10:113-123
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Hysterectomy, business.industry, Large cell, medicine.medical_treatment, Microsatellite instability, Neuroendocrine tumors, Endometrium, medicine.disease, medicine.anatomical_structure, Cancer cell, medicine, Immunohistochemistry, business, Etoposide, medicine.drug
الوصف: Endometrial neuroendocrine tumors are rare, accounting less than 1% of endometrial cancers. They include small cell neuroendocrine carcinoma (NEC) and large cell NEC and usually occur in postmenopausal patients. Although common symptoms include postmenopausal bleeding, most patients are diagnosed at an advanced stage. We report an extremely rare case of small cell NEC developed in the endometrium of a 75-year-old Japanese woman. This case was initially suspected based on the findings of endometrial cytology: a number of small round malignant cells were present on the endometrial smear specimens. The immunocytochemical and immunohistochemical examinations revealed diffusely cytoplasmic positive reaction of neuron specific enolase (NSE) and partially membranous positive reaction of CD56 in the small cancer cells. They showed PAX-8-positive reaction, but did not express microsatellite instability high. Electron micrography showed several dense-core secretory granules in the cytoplasm of cancer cells. Despite multiple lung metastases, the patient underwent a hysterectomy and salpingo-oophorectomy in order to control excessive genital bleeding. She received six courses of adjuvant chemotherapy based on etoposide and cisplatin, and survived healthy eight months after the first visit without any viability of lung metastases.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::88266b182ac239450aea58af6d7c08b0
https://doi.org/10.4236/ojpathology.2020.104011 -
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المؤلفون: Kentaro Niwa, Hiroaki Kurogi, Masakazu Hori, Shuhei Sawayama, Toyomitsu Horii
المصدر: NIPPON SUISAN GAKKAISHI. 85:406-420
مصطلحات موضوعية: Abalone, Ecology, Aquatic Science, Biology, Nursery habitat, Natural (archaeology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::159082131c509b1b5a13ddf446a51c9c
https://doi.org/10.2331/suisan.19-00009
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