يعرض 1 - 10 نتائج من 64 نتيجة بحث عن '"Koh FH"', وقت الاستعلام: 1.43s تنقيح النتائج
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    دورية أكاديمية

    المؤلفون: Koh FH; Sengkang General Hospital, SingHealth, Singapore., Chew LM; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Wong N; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Kow AW; National University Hospital, National University Health System, Singapore., Yap D; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Ng S; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Ng J; National University Hospital, National University Health System, Singapore., Tan MY; Khoo Teck Puat Hospital, National Healthcare Group, Singapore., Lee DJ; Khoo Teck Puat Hospital, National Healthcare Group, Singapore., Au-Yong AP; Singapore General Hospital, SingHealth, Singapore., Yan CC; Sengkang General Hospital, SingHealth, Singapore., Darmawirya P; Tan Tock Seng Hospital, National Healthcare Group, Singapore., Jayachandran B; Woodlands General Hospital, Woodlands Health, Singapore., Maier A; Alexandra Hospital, National University Health System, Singapore., El Yeong H; Khoo Teck Puat Hospital, National Healthcare Group, Singapore., Chew ST; Changi General Hospital, Singhealth, Singapore., Foo FJ; Sengkang General Hospital, SingHealth, Singapore., How KY; Tan Tock Seng Hospital, National Healthcare Group, Singapore., Ng DH; Tan Tock Seng Hospital, National Healthcare Group, Singapore.

    المصدر: International journal of surgery (London, England) [Int J Surg] 2024 May 03. Date of Electronic Publication: 2024 May 03.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101228232 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-9159 (Electronic) Linking ISSN: 17439159 NLM ISO Abbreviation: Int J Surg Subsets: MEDLINE

    مستخلص: Background: Ageing population is a worldwide phenomenon with correspondingly higher proportion of older patients being treated in the hospital setting. Sarcopenia, which increases with age, has serious negative implications on health, hospitalization and overall postoperative recovery. There is no mutual consensus on perioperative management of sarcopenia in surgical patients in Singapore. The purpose of this study is to create greater clarity pertaining to the recognition of sarcopenia, the application of assessment criteria of sarcopenia and perioperative management of surgical patients in Singapore.
    Methods: A modified Delphi consensus consisting of a panel of experts from Singapore forming a multidisciplinary team, including surgeons, geriatricians, anesthesiologists, physiotherapists and dieticians. Eight recommendations were proposed by the steering committee. Literature search from MEDLINE, Embase and Scopus for articles up till June 2023 were performed to support recommendation statements. The expert panel voted on agreement to recommendation statements and graded the level of evidence supporting each statement through surveys to achieve consensus, set at 85% a priori.
    Results: The panelists underwent two rounds of anonymized, independent voting before reaching consensus for all eight statements. After the first round, seven statements reached consensus, including the corresponding grading for level of evidence. The statement which did not achieve consensus was revised with supporting literature and after the second round of survey, all eight statements and level of evidence reached consensus, completing the Delphi process. These eight statements covered themes to (1) encourage the identification of sarcopenia, (2) guide pre-operative and (3) post-operative management of sarcopenia.
    Conclusion: With the varying approaches in perioperative management, poor understanding of and identification of sarcopenia can result in suboptimal management of sarcopenia in surgical patients. Given the abundance of evidence linking beneficial impact on recovery and post-operative complications with prudent management of sarcopenia, it is imperative and urgent to achieve awareness and consensus.
    (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)

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    دورية أكاديمية

    المؤلفون: Jin-Yang Sia C; Department of Colorectal Surgery, Sengkang General Hospital, Singapore., Wee SL; Department of Anaesthesiology, Khoo Teck Phuat Hospital, Singapore., Au-Yong PS; Department of Anaesthesiology and Perioperative Science, Singapore General Hospital, Singapore., Lie SA; Department of Anaesthesiology and Perioperative Science, Singapore General Hospital, Singapore., Tan WJ; Department of Colorectal Surgery, Sengkang General Hospital, Singapore., Foo FJ; Department of Colorectal Surgery, Sengkang General Hospital, Singapore., Kam JH; Department of General Surgery, Sengkang General Hospital, Singapore., Lee DJ; Department of Colorectal Surgery, Khoo Teck Phuat Hospital, Singapore., Koh FH; Department of Colorectal Surgery, Sengkang General Hospital, Singapore.

    المصدر: International journal of surgery (London, England) [Int J Surg] 2024 Apr 03. Date of Electronic Publication: 2024 Apr 03.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101228232 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-9159 (Electronic) Linking ISSN: 17439159 NLM ISO Abbreviation: Int J Surg Subsets: MEDLINE

    مستخلص: Background: Multimodal analgesia is now widely practised to minimise postoperative opioid consumption while optimising pain control. The aim of this meta-analysis was to assess the analgesic efficacy of erector spinae plane block (ESPB) in patients undergoing laparoscopic abdominal surgeries. This will be determined by perioperative opioid consumption, subjective pain scores and incidences of postoperative nausea and vomiting.
    Methods: We systemically searched electronic databases for randomised controlled trials (RCTs) published up to February 2023 comparing ESPB with other adjuvant analgesic techniques in laparoscopic abdominal surgeries. Nine randomised controlled trials encompassing 666 subjects were included in our study.
    Results: ESPB was shown to reduce postoperative opioid consumption [mean difference (MD) of -5.95mg (95% CI: -8.86 to -3.04; P< 0.0001); I2=89%], intraoperative opioid consumption [mean difference (MD) of -102.4mcg (95% CI: -145.58 to -59.21; P< 0.00001); I2=39%] and incidence of nausea [RR 0.38 (95% CI: 0.25 to 0.60; P< 0.0001); I2=0%] and vomiting [RR 0.32 (95% CI: 0.17 to 0.63; P=0.0009); I2=0%] in laparoscopic abdominal surgeries. Subgroup analysis on laparoscopic colorectal surgeries further showed reduction in postoperative pain scores [mean difference (MD) of -0.68 (95% CI: -0.94 to -0.41); P< 0.00001; I2=0%].
    Conclusions: This study concludes that ESPB is a valuable technique with proven efficacy to potentially promote faster postoperative recovery through optimising pain control while minimising opioid requirements.
    (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)

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    دورية أكاديمية

    المؤلفون: Soo JM; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Koh FH; Colorectal Service, Department of General Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.

    المصدر: ANZ journal of surgery [ANZ J Surg] 2024 Mar; Vol. 94 (3), pp. 362-365. Date of Electronic Publication: 2023 Dec 27.

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Wiley-Blackwell Publishing Asia Country of Publication: Australia NLM ID: 101086634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1445-2197 (Electronic) Linking ISSN: 14451433 NLM ISO Abbreviation: ANZ J Surg Subsets: MEDLINE

    مستخلص: Background: As the serrated pathway has gained prominence as an alternative colorectal carcinogenesis pathway, sessile serrated adenomas or polyps (SSA/P) have been highlighted as lesions to rule out during colonoscopy. These lesions are however morphologically difficult to detect on endoscopy and can be mistaken for hyperplastic polyps due to similar endoscopic features. With the underlying nature of rapid progression and malignant transformation, interval cancer is a likely consequence of undetected or overlooked SSA/P. Real-time artificial intelligence (AI)-assisted colonoscopy via the computer-assisted detection system (CADe) is an increasingly useful tool in improving adenoma detection rate by providing a second eye during the procedure. In this article, we describe a guide through a video to illustrate the detection of SSA/P during AI-assisted colonoscopy.
    Methods: Consultant-grade endoscopists utilized real-time AI-assisted colonoscopy device, as part of a larger prospective study, to detect suspicious lesions which were later histopathologically confirmed to be SSA/P.
    Results: All lesions were picked up by the CADe where a real-time green box highlighted suspicious polyps to the clinician. Three SSA/P of varying morphology are described with reference to classical SSA/P features and with comparison to the features of the hyperplastic polyp found in our study. All three SSA/P observed are in keeping with the JNET Classification (Type 1).
    Conclusion: In conclusion, CADe is a most useful aid to clinicians during endoscopy in the detection of SSA/P but must be complemented with factors such as good endoscopy skill and bowel prep for effective detection, and biopsy coupled with subsequent accurate histological diagnosis.
    (© 2023 Royal Australasian College of Surgeons.)

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    دورية أكاديمية

    المؤلفون: Wu J; Division of Surgery, Sengkang General Hospital, Singapore., Chi H; Division of Surgery, Sengkang General Hospital, Singapore., Kok S; Department of Radiology, Sengkang General Hospital, Singapore., Chua JMW; Institute of Molecular and Cell Biology, Agency for Science Technology and Research, Singapore., Huang XX; Institute of Molecular and Cell Biology, Agency for Science Technology and Research, Singapore., Zhang S; Duke-NUS Graduate Medical School, National Cancer Centre Singapore, Singapore., Mah S; Department of Physiotherapy, Sengkang General Hospital, Singapore., Foo LX; Department of Physiotherapy, Sengkang General Hospital, Singapore., Peh HY; Department of Dietetics, Sengkang General Hospital, Singapore., Lee HB; Department of Dietetics, Sengkang General Hospital, Singapore., Tay P; Department of Dietetics, Sengkang General Hospital, Singapore., Tong C; Department of Dietetics, Sengkang General Hospital, Singapore., Ladlad J; Division of Surgery, Sengkang General Hospital, Singapore., Tan CHM; Division of Surgery, Sengkang General Hospital, Singapore., Khoo N; Division of Surgery, Sengkang General Hospital, Singapore., Aw D; Division of Surgery, Sengkang General Hospital, Singapore., Chong CXZ; Division of Surgery, Sengkang General Hospital, Singapore., Ho LML; Division of Surgery, Sengkang General Hospital, Singapore., Sivarajah SS; Division of Surgery, Sengkang General Hospital, Singapore., Ng J; Division of Surgery, Sengkang General Hospital, Singapore., Tan WJH; Division of Surgery, Sengkang General Hospital, Singapore., Foo FJ; Division of Surgery, Sengkang General Hospital, Singapore., Teh BT; Duke-NUS Graduate Medical School, National Cancer Centre Singapore, Singapore., Koh FH; Division of Surgery, Sengkang General Hospital, Singapore.

    المصدر: Annals of coloproctology [Ann Coloproctol] 2024 Feb; Vol. 40 (1), pp. 3-12. Date of Electronic Publication: 2023 Mar 31.

    نوع المنشور: Journal Article; Review

    بيانات الدورية: Publisher: Korean Society of Coloproctology Country of Publication: Korea (South) NLM ID: 101605121 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2287-9714 (Print) Linking ISSN: 22879714 NLM ISO Abbreviation: Ann Coloproctol Subsets: PubMed not MEDLINE

    مستخلص: Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle mass and strength, has been well described to be associated with numerous poor postoperative outcomes, such as increased perioperative mortality, postoperative sepsis, prolonged length of stay, increased cost of care, decreased functional outcome, and poorer oncological outcomes in cancer surgery. Multimodal prehabilitation, as a concept that involves boosting and optimizing the preoperative condition of a patient prior to the upcoming stressors of a surgical procedure, has the purported benefits of reversing the effects of sarcopenia, shortening hospitalization, improving the rate of return to bowel activity, reducing the costs of hospitalization, and improving quality of life. This review aims to present the current literature surrounding the concept of sarcopenia, its implications pertaining to colorectal cancer and surgery, a summary of studied multimodal prehabilitation interventions, and potential future advances in the management of sarcopenia.

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    دورية أكاديمية

    المؤلفون: Heng MWY; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6, Singapore, 169856, Singapore.; University of Cambridge, Cambridge, England., Chan AWD; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6, Singapore, 169856, Singapore., Man REK; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6, Singapore, 169856, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Fenwick EK; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6, Singapore, 169856, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Chew STH; Department of Geriatric Medicine, Changi General Hospital, Singapore, Singapore., Tay L; Department of Geriatric Medicine, Sengkang General Hospital, Sengkang, Singapore., Sien NY; Rehabilitation Medicine, Division of Medicine, Singapore General Hospital, Singapore, Singapore., Ng D; Department of Nuclear Medicine, Singapore General Hospital, Singapore, Singapore., Koh FH; Department of General Surgery, Sengkang General Hospital, Singapore, Singapore., Yong EL; Department of Obstetrics & Gynecology, National University of Singapore, Singapore, Singapore., Gupta P; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6, Singapore, 169856, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Lamoureux EL; Singapore Eye Research Institute (SERI), The Academia, 20 College Road, Level 6, Singapore, 169856, Singapore. ecosse.lamoureux@duke-nus.edu.sg.; Duke-NUS Medical School, Singapore, Singapore. ecosse.lamoureux@duke-nus.edu.sg.; The University of Melbourne, Melbourne, Australia. ecosse.lamoureux@duke-nus.edu.sg.

    المصدر: BMC geriatrics [BMC Geriatr] 2023 Dec 05; Vol. 23 (1), pp. 802. Date of Electronic Publication: 2023 Dec 05.

    نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

    بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968548 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2318 (Electronic) Linking ISSN: 14712318 NLM ISO Abbreviation: BMC Geriatr Subsets: MEDLINE

    مستخلص: Background: We explored the relationships between sarcopenia (SP), osteoporosis (OP), obesity (OB), (alone and in combination) with physical frailty (PF) in a multi-ethnic, population-based study of Asians aged ≥ 60 years.
    Methods: Participants were enrolled from the PopulatION HEalth and Eye Disease PRofile in Elderly Singaporeans Study (PIONEER) study. PF was defined using the modified Fried phenotype; SP using the Asian Working Group for Sarcopenia 2019; OP using bone mineral density scores; and OB using the fat mass index. Modified Poisson regression models investigated the associations between exposures and PF, and the relative excess rates of PF due to interactions (RERI) to determine synergistic or antagonistic interactions.
    Results: Of the 2643 participants, 54.8% was female; and 49.8%, 25.1%, 25.0% were Chinese, Indians, and Malays, respectively. 25%, 19.0% and 6.7% participants had OB only, SP only, and OP only, respectively. A total of 356 (17.5%), 151 (7.4%) and 97 (4.8%) had osteosarcopenia (OSP), sarcopenic obesity (SOB) and osteo-obesity (OOB), respectively; while 70 (3.5%) had all 3 morbid conditions (osteosarcopenic obesity, OSO). Both SP only and OB only were strongly associated with increased rates of PF (RR: 2.53, 95% CI: 1.95, 3.29; RR: 2.05, 95% CI: 1.58, 2.66 respectively); but not OP. Those with OSP, OOB and SOB were also associated with high risks of PF (RR: 2.82, 95% CI: 2.16, 3.68; RR: 2.34, 95% CI: 1.69, 3.23; and RR: 2.58, 95% CI: 1.95, 3.41, respectively) compared to robust individuals. Critically, individuals with OSO had the highest relative risk of having PF (RR: 3.06, CI: 2.28, 4.11). Only the sarcopenia-obesity interaction was significant, demonstrating negative synergism (antagonism). The concurrent presence of SP and OB was associated with a 100% lower rate of PF compared to the sum of the relatively rates of SP only and OB only.
    Conclusion: The prevalence of SP, OB and OP, alone and combined, is substantial in older Asians and their early identification is needed to mitigate the risk of frailty. OB may interact with SP in an antagonistic manner to moderate rates of frailty. Further longitudinal studies are needed to address causality and mechanistic underpinnings our findings.
    (© 2023. The Author(s).)

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    تقرير

    المؤلفون: Seng NW; Ministry of Health Holdings, Singapore, Singapore.; Sengkang General Hospital, Singapore, Singapore., Barco JB; Sengkang General Hospital, Singapore, Singapore., Wong MH; Sengkang General Hospital, Singapore, Singapore., Lim KX; Sengkang General Hospital, Singapore, Singapore., Peh WM; Sengkang General Hospital, Singapore, Singapore., Ng CT; Sengkang General Hospital, Singapore, Singapore., Cushway T; The Iron Suites Medical Centre, Singapore, Singapore., Foo FJ; Sengkang General Hospital, Singapore, Singapore., Koh FH; Sengkang General Hospital, Singapore, Singapore.

    المصدر: Transfusion medicine (Oxford, England) [Transfus Med] 2023 Dec; Vol. 33 (6), pp. 503-508. Date of Electronic Publication: 2023 Jun 01.

    نوع المنشور: Case Reports

    بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9301182 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3148 (Electronic) Linking ISSN: 09587578 NLM ISO Abbreviation: Transfus Med Subsets: MEDLINE

    مستخلص: Objectives: This case series would like to highlight hypophosphatemia related to ferric carboxymaltose and its adverse clinical consequences.
    Background: Intravenous iron supplementation is a good alternative to oral iron replacement in iron deficiency anaemia due to its ability to correct iron deficit with minimal infusions without incurring the gastrointestinal side effects of oral iron replacement. Ferric carboxymaltose is one common formula for intravenous iron supplementation. However, an increasingly recognised adverse side-effect of intravenous ferric carboxymaltose is hypophosphatemia. There has been increasing reports and studies highlighting hypophosphatemia related to intra-venous iron therapy. Though initially thought to be transient and asymptomatic, recent studies have shown that persistent hypophosphatemia in iron therapy can result in debilitating disease including myopathy, fractures and osteomalacia.
    Methods: A retrospective analysis of all patients who had ferric carboxymaltose was performed.
    Results: We highlight 3 cases where hyposphatemia affected the clinical outcomes.
    Conclusion: With the increased use of IV iron it is important to be aware of the high potential for hypophosphatemia secondary to ferric carboxymaltose.
    (© 2023 British Blood Transfusion Society.)

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    دورية أكاديمية

    المؤلفون: Wong AW; Plastic, Reconstructive and Aesthetic Surgery Service, Department of General Surgery, Sengkang General Hospital, Singapore, Singapore., Tan GH; Plastic, Reconstructive and Aesthetic Surgery Service, Department of General Surgery, Sengkang General Hospital, Singapore, Singapore., Koh FH; Colorectal Service, Department of General Surgery, Sengkang General Hospital, Singapore, Singapore., Chew MH; Colorectal Service, Department of General Surgery, Sengkang General Hospital, Singapore, Singapore.

    المصدر: Archives of plastic surgery [Arch Plast Surg] 2023 Oct 05; Vol. 50 (5), pp. 496-500. Date of Electronic Publication: 2023 Oct 05 (Print Publication: 2023).

    نوع المنشور: Journal Article

    بيانات الدورية: Publisher: Korean Society of Plastic and Reconstructive Surgeons Country of Publication: Korea (South) NLM ID: 101577999 Publication Model: eCollection Cited Medium: Print ISSN: 2234-6163 (Print) Linking ISSN: 22346163 NLM ISO Abbreviation: Arch Plast Surg Subsets: PubMed not MEDLINE

    مستخلص: Fournier's gangrene is a life-threatening infection which requires prompt recognition, early surgical debridement of unhealthy tissue, and initiation of broad-spectrum antibiotics. Relook debridement are usually performed until all the devitalized tissue has been removed. Involvement of the anal sphincter may result in significant morbidity such as permanent incontinence. Dynamic reconstruction of the anal sphincter has always been one of the holy grails in the field of pelvic reconstruction. We demonstrate a new method of camera shutter style double-opposing gracilis muscle flaps that allows dynamic sphincteric function without the need for electrostimulation. The bilateral gracilis muscles are inset in a fashion that allows orthograde contraction of the muscle to narrow and collapse the neoanal opening. With biofeedback training, the patient is able to regain dynamic continence and return to function without a stoma. There was also no need for neurotization or microsurgery techniques to restore sphincteric function to the anus. The patient was able to reverse his stoma 14 months after the initial insult and reconstruction with biofeedback training without the use of electrostimulation.
    Competing Interests: Conflict of Interest None declared.
    (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ).)

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    دورية أكاديمية

    المؤلفون: Tham S; Department of General Surgery, Sengkang General Hospital, SingHealth Services, Singapore., Koh FH; Colorectal Service, Department of General Surgery, Sengkang General Hospital, SingHealth Services, Singapore.; SKH Endoscopy Centre, Division of Hyperacute Care, Sengkang General Hospital, SingHealth Services, Singapore., Ladlad J; Colorectal Service, Department of General Surgery, Sengkang General Hospital, SingHealth Services, Singapore.; SKH Endoscopy Centre, Division of Hyperacute Care, Sengkang General Hospital, SingHealth Services, Singapore., Chue KM; Department of General Surgery, Sengkang General Hospital, SingHealth Services, Singapore.; SKH Endoscopy Centre, Division of Hyperacute Care, Sengkang General Hospital, SingHealth Services, Singapore., Lin CL; SKH Endoscopy Centre, Division of Hyperacute Care, Sengkang General Hospital, SingHealth Services, Singapore.; Department of Gastroenterology and Hepatology, Sengkang General Hospital, SingHealth Services, Singapore., Teo EK; SKH Endoscopy Centre, Division of Hyperacute Care, Sengkang General Hospital, SingHealth Services, Singapore.; Department of Gastroenterology and Hepatology, Sengkang General Hospital, SingHealth Services, Singapore., Foo FJ; Colorectal Service, Department of General Surgery, Sengkang General Hospital, SingHealth Services, Singapore.; SKH Endoscopy Centre, Division of Hyperacute Care, Sengkang General Hospital, SingHealth Services, Singapore.

    المصدر: Annals of coloproctology [Ann Coloproctol] 2023 Oct; Vol. 39 (5), pp. 385-394. Date of Electronic Publication: 2023 Mar 10.

    نوع المنشور: Journal Article; Review

    بيانات الدورية: Publisher: Korean Society of Coloproctology Country of Publication: Korea (South) NLM ID: 101605121 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2287-9714 (Print) Linking ISSN: 22879714 NLM ISO Abbreviation: Ann Coloproctol Subsets: PubMed not MEDLINE

    مستخلص: The development of deep learning systems in artificial intelligence (AI) has enabled advances in endoscopy, and AI-aided colonoscopy has recently been ushered into clinical practice as a clinical decision-support tool. This has enabled real-time AI-aided detection of polyps with a higher sensitivity than the average endoscopist, and evidence to support its use has been promising thus far. This review article provides a summary of currently published data relating to AI-aided colonoscopy, discusses current clinical applications, and introduces ongoing research directions. We also explore endoscopists' perceptions and attitudes toward the use of this technology, and discuss factors influencing its uptake in clinical practice.