المؤلفون: Murilo Carvalho, Adriana Franco Paes Leme, Juliana Helena Costa Smetana, Bianca Alves Pauletti, Alisson C. Cardoso, Mauro M. Teixeira, Paulo S. Oliveira, Laura H. V. G. Gil, José Xavier-Neto, Carolina Borsoi Moraes Holanda de Freitas, Ana Helena Macedo Pereira, Kleber G. Franchini, Carla Letícia Bandeira, Ângela Maria Sousa Costa, Estela Bevilacqua, Rafael Elias Marques, Marli Tenório Cordeiro, Daniela C. Granato, Luana Nunes Santos, Marcio C. Bajgelman, Ângela Saito, Lucio H. Freitas-Junior, Vivian Vasconcelos Costa, Bruno dos Santos Pascoalino, Sílvio Roberto Consonni

المصدر: PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005363 (2017)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Neglected Tropical Diseases

مصطلحات موضوعية: Male, RNA viruses, 0301 basic medicine, Embryology, Microcephaly, Pathology, Placenta, Maternal Health, Intrauterine growth restriction, Pathology and Laboratory Medicine, Mice, 0302 clinical medicine, Pregnancy, Medicine and Health Sciences, Pregnancy Complications, Infectious, reproductive and urinary physiology, Arthrogryposis, Zika Virus Infection, lcsh:Public aspects of medicine, Obstetrics and Gynecology, Animal Models, Viral Load, Teratogens, Infectious Diseases, Neurology, Experimental Organism Systems, Medical Microbiology, In utero, Viral Pathogens, Viruses, embryonic structures, Female, Anatomy, Pathogens, medicine.symptom, Hydrocephalus, Research Article, medicine.medical_specialty, lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, 030231 tropical medicine, Mouse Models, Biology, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Model Organisms, Virology, medicine, Animals, Humans, Microbial Pathogens, Fetuses, Fetus, Flaviviruses, Embryos, Reproductive System, Organisms, Public Health, Environmental and Occupational Health, Biology and Life Sciences, lcsh:RA1-1270, Zika Virus, medicine.disease, HISTOLOGIA, Teratology, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Neurulation, Immunology, Women's Health, Viral Transmission and Infection, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3087e52f7b31c40486d0904fb0647e6b
http://europepmc.org/articles/PMC5322881?pdf=render

المؤلفون: Giulia Bianchini, Bernhard Ellinger, Lucio H. Freitas-Junior, Giulia Fiorani, Eulogio López-Montero, Maria Laura Bolognesi, Maria Teresa Molina, Gesa Witt, Elisa Uliassi, R. Luise Krauth-Siegel, Maria Paola Costi, Romana Fato, Christian Bergamini, Federico Falchi, Sheraz Gul, J. Carlos Menéndez, Carolina B. Moraes, Maria Kuzikov, Andrea Cavalli, Chiara Borsari

المساهمون: DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE, Facolta' di MEDICINA e CHIRURGIA, AREA MIN. 03 - Scienze chimiche, AREA MIN. 05 - Scienze biologiche, Publica, Uliassi, Elisa, Fiorani, Giulia, Krauth-Siegel, R. Luise, Bergamini, Christian, Fato, Romana, Bianchini, Giulia, Carlos Menéndez, J., Molina, Maria Teresa, López-Montero, Eulogio, Falchi, Federico, Cavalli, Andrea, Gul, Sheraz, Kuzikov, Maria, Ellinger, Bernhard, Witt, Gesa, Moraes, Carolina B., Freitas-Junior, Lucio H., Borsari, Chiara, Costi, Maria Paola, Bolognesi, Maria Laura

مصطلحات موضوعية: 0301 basic medicine, Parasitic Sensitivity Test, Models, Molecular, Crassiflorone, Trypanosomiasi, Dehydrogenase, 01 natural sciences, NADPH Oxidoreductases, chemistry.chemical_compound, Parasitic Sensitivity Tests, Coumarins, Models, Drug Discovery, NADH, NADPH Oxidoreductases, Leishmaniasis, Glyceraldehyde 3-phosphate dehydrogenase, Natural products, Tumor, biology, Trypanocidal Agent, Molecular Structure, Quinones, Glyceraldehyde-3-Phosphate Dehydrogenases, General Medicine, Trypanocidal Agents, Biochemistry, Quinone, Glyceraldehyde-3-phosphate dehydrogenase, Diospyros crassiflora, Drug, Human, Leishmaniasi, Trypanosoma cruzi, Trypanosoma brucei brucei, Trypanosoma brucei, Coumarin, Natural product, Cell Line, Dose-Response Relationship, 03 medical and health sciences, Structure-Activity Relationship, Trypanosomiasis, Cell Line, Tumor, Structure–activity relationship, Humans, Trypanocidal agent, Trypanocidal activity, Pharmacology, Dose-Response Relationship, Drug, 010405 organic chemistry, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Molecular, biology.organism_classification, 0104 chemical sciences, 030104 developmental biology, Trypanothione reductase, chemistry, NADH, biology.protein, NADH, NADPH Oxidoreductase

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd27927f3e2d6ad95ba8f890079d66db
http://hdl.handle.net/11585/621363

المؤلفون: Carolina B. Moraes, Michael N. Balfour, Hélio A. Stefani, Caio Haddad Franco, Lucio H. Freitas-Junior

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: Models, Molecular, Chagas disease, Pyridines, Stereochemistry, Trypanosoma cruzi, 010402 general chemistry, 01 natural sciences, Structure-Activity Relationship, Parasitic Sensitivity Tests, parasitic diseases, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Chagas Disease, Pyrroles, Amastigote, Cells, Cultured, Trypanocidal agent, Pharmacology, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, General Medicine, TRYPANOSOMA, biology.organism_classification, medicine.disease, Trypanocidal Agents, 0104 chemical sciences, Nitroimidazoles, Benznidazole, High-content screening, Trypanosoma, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fc77ed813667c523c985ccba3baad7

المؤلفون: Lici A. Schurig-Briccio, Kai Li, Benoit Lechartier, Lucio H. Freitas-Junior, Feifei Ren, Venugopal Pujari, Rey-Ting Guo, Douglas A. Mitchell, Tong Jiang, Eric Oldfield, Hong Sun, Peter Orlean, Shannon Bogue, Dean C. Crick, Xinxin Feng, Wei Zhu, Katie J. Molohon, Guodong Rao, Yi Liang Liu, Stewart T. Cole, Anmol Gulati, Hongliang Yang, Ashutosh Upadhyay, Fabio L. Fontes, Giovana Aparecida de Souza Cintra, Robert B. Gennis, Joo Hwan No, Yujie Li

المصدر: Journal of Medicinal Chemistry; Vol 57
Journal of Medicinal Chemistry

مصطلحات موضوعية: Models, Molecular, Tuberculosis, Plasmodium falciparum, SQ109, Antitubercular Agents, Antineoplastic Agents, Breast Neoplasms, Drug resistance, Article, Microbiology, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Anti-Infective Agents, Drug Discovery, medicine, Tumor Cells, Cultured, Humans, Malaria, Falciparum, 030304 developmental biology, Cell Proliferation, 0303 health sciences, biology, Bacteria, Molecular Structure, 030306 microbiology, Drug discovery, Membrane transport protein, Fungi, Membrane Transport Proteins, biology.organism_classification, medicine.disease, 3. Good health, chemistry, Drug Design, biology.protein, MCF-7 Cells, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88981625e909196857c589a5f5e4984a

المؤلفون: Jinhwa Lee, Sunju Kong, Michel Liuzzi, Rita Song, Gyongseon Yang, Junghyun Goo, Jair L. Siqueira-Neto, Dawoon Han, Nakyung Lee, Sangmi Oh, Bosung Kwon, Lucio H. Freitas-Junior

المصدر: Med. Chem. Commun.. 5:142-146

مصطلحات موضوعية: Pharmacology, biology, medicine.drug_class, Stereochemistry, Organic Chemistry, Leishmania donovani, Pharmaceutical Science, Carboxamide, biology.organism_classification, Biochemistry, In vitro, Drug Discovery, Extracellular, medicine, Molecular Medicine, Bioassay, Cytotoxicity, Amastigote, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::42081849ca9dca2bce1d52c67b9b25e5
https://doi.org/10.1039/c3md00299c

المؤلفون: Seunghyun Moon, Jair L Siqueira-Neto, Carolina Borsoi Moraes, Gyongseon Yang, Myungjoo Kang, Lucio H Freitas-Junior, Michael A E Hansen

المصدر: Public Library of Science, PLOS ONE. 9(2):1-12

الإتاحة: https://ideas.repec.org/a/plo/pone00/0087188.html

المؤلفون: Paloma Tejera Nevado, Maria Paola Costi, María Jesús Corral, Joachim Clos, Claudia Danielli Pereira Bertolacini, Caio Haddad Franco, Lucio H. Freitas-Junior, Vanessa Fontana, Markus Wolf, Annalisa Tait, Sheraz Gul, Gesa Witt, Juan J. Torrado, José María Alunda, Luca Costantino, Jeanette Reinshagen, Pasquale Linciano, Anabela Cordeiro-da-Silva, Nuno Santarém, Ana Isabel Olías, Bernhard Ellinger, Pascoalino Bruno dos Santos, Carolina B. Moraes, Philip Gribbon, Catarina Baptista, Maria Kuzikov, Laura M. Alcântara, Chiara Borsari, Stefania Ferrari

المساهمون: Publica

المصدر: European journal of medicinal chemistry. 126

مصطلحات موضوعية: 0301 basic medicine, Antiparasitic, medicine.drug_class, Stereochemistry, 02 engineering and technology, Trypanosoma brucei, 03 medical and health sciences, Mice, Chalcones, Cyclodextrins formulation, Early toxicity studies, Leishmania infantum, Trypanosoma cruzi, Animals, Antiparasitic Agents, Cell Line, Tumor, Cyclodextrins, Drug Carriers, Solubility, Trypanosomatina, Pharmacology, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, parasitic diseases, Drug Discovery, medicine, biology, Chemistry, General Medicine, 021001 nanoscience & nanotechnology, biology.organism_classification, Antiparasitic agent, 3. Good health, Bioavailability, 030104 developmental biology, 0210 nano-technology, Drug carrier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dee3c53a54e2606c764ceba258643ef
https://pubmed.ncbi.nlm.nih.gov/28064141

المؤلفون: Laura H. V. G. Gil, Bruno dos Santos Pascoalino, Marli Tenório Cordeiro, Lucio H. Freitas-Junior, Gilles Courtemanche

المصدر: F1000Research

مصطلحات موضوعية: 0301 basic medicine, Microcephaly, FDA-approved drugs, Antiviral chemotherapy, medicine.drug_class, 030106 microbiology, Disease, General Biochemistry, Genetics and Molecular Biology, Virus, Dengue fever, Zika virus, 03 medical and health sciences, Zika, Virology, medicine, General Pharmacology, Toxicology and Pharmaceutics, Drug Discovery & Design, General Immunology and Microbiology, biology, Viral Infections (without HIV), business.industry, Drug discovery, General Medicine, Articles, medicine.disease, biology.organism_classification, 030104 developmental biology, Immunology, Antiviral drug, business, Research Article, High content screening drug discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eed9f686956eb901a150da40a9d8acd
http://europepmc.org/articles/PMC5112578

المؤلفون: Luiz Tadeu Moraes Figueiredo, Rafaela Milan Bonotto, Soraya Jabur Badra, Carolina B. Moraes, Glaucia Souza-Almeida, Lucio H. Freitas-Junior

المصدر: F1000Research. 7:1730

مصطلحات موضوعية: 0301 basic medicine, Drug, General Immunology and Microbiology, business.industry, Drug discovery, Phenotypic screening, media_common.quotation_subject, 030106 microbiology, virus diseases, General Medicine, medicine.disease_cause, Virology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Drug repositioning, 030104 developmental biology, Drug development, High-content screening, Medicine, Chikungunya, General Pharmacology, Toxicology and Pharmaceutics, business, Repurposing, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::76a363a802db007f0bf0785e2e1f394a
https://doi.org/10.12688/f1000research.16498.1

المؤلفون: Seunghyun Moon, Sukjun Lee, Heechang Kim, Lucio H Freitas-Junior, Myungjoo Kang, Lawrence Ayong, Michael A E Hansen

المصدر: Public Library of Science, PLOS ONE. 8(4):1-12

الإتاحة: https://ideas.repec.org/a/plo/pone00/0061812.html