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المؤلفون: Ana Luiza Pamplona Mosimann, Lucio H. Freitas-Junior, Claudia Nunes Duarte dos Santos, Hazel E.E. Wong, Yong-Jun Kwon, Camila T. da Silva, Deu John M. Cruz, Katja Fink, Sumathy Velumani, Jinyeong Heo
المصدر: Antiviral research. 110
مصطلحات موضوعية: Dengue virus, Biology, medicine.disease_cause, Virus Replication, Antiviral Agents, Virus, Dengue fever, Cell Line, Smad7 Protein, Dengue, eIF-2 Kinase, Virology, medicine, Humans, Kinome, RNA, Small Interfering, Gene, Pharmacology, Gene knockdown, Dengue Virus, medicine.disease, High-Throughput Screening Assays, Phosphotransferases (Alcohol Group Acceptor), Cell culture, Host-Pathogen Interactions, Hepatocytes, RNA Interference, Viral load, Protein Kinases
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المؤلفون: Sukjun Lee, Protus Arrey Tarkang, Lucio H. Freitas-Junior, Eunyoung Lee, Gabriel A. Agbor, Lawrence Ayong, Kathrin Diehl Franzoi, Diego Vivarelli, Faith A. Okalebo, Michel Liuzzi, Anastasia N. Guantai, Tsabang Nole
المصدر: BioMed Research International, Vol 2014 (2014)
BioMed Research Internationalمصطلحات موضوعية: Article Subject, Plasmodium falciparum, Drug Evaluation, Preclinical, lcsh:Medicine, Pharmacology, General Biochemistry, Genetics and Molecular Biology, Antimalarials, Cymbopogon citratus, Humans, Mangifera, Malaria, Falciparum, EC50, Psidium, General Immunology and Microbiology, biology, Traditional medicine, Plant Extracts, Chemistry, lcsh:R, Ocimum gratissimum, Hep G2 Cells, General Medicine, biology.organism_classification, Hep G2, Solvents, Carica, Citrus × sinensis, Research Article
وصف الملف: text/xhtml
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المؤلفون: Carolina B. Moraes, Seung-Hyun Moon, Michael Adsetts Edberg Hansen, Lucio H. Freitas-Junior, Jair L. Siqueira-Neto, Myungjoo Kang, Gyongseon Yang
المصدر: PLoS ONE, Vol 9, Iss 2, p e87188 (2014)
PLoS ONEمصطلحات موضوعية: Trypanosoma, Trypanosoma cruzi, Image Processing, High-throughput screening, Cell, Drug Evaluation, Preclinical, Parasitic Sensitivity Tests, lcsh:Medicine, Protozoology, Biology, Microbiology, Engineering, Drug Discovery, Image Processing, Computer-Assisted, medicine, Animals, Humans, Parasites, Nifurtimox, lcsh:Science, Cell Nucleus, Multidisciplinary, Applied Mathematics, Intracellular parasite, lcsh:R, Reproducibility of Results, biology.organism_classification, Trypanocidal Agents, High-Throughput Screening Assays, medicine.anatomical_structure, Benznidazole, Computer Science, Signal Processing, Human parasite, Parastic Protozoans, lcsh:Q, Algorithm, Algorithms, Mathematics, Research Article, Biotechnology, medicine.drug
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المؤلفون: Camila T. da Silva, Joo Hwan No, Michael Adsetts Edberg Hansen, Olivier Schwartz, Deu John M. Cruz, Rafaela Milan Bonotto, Lucio H. Freitas-Junior, Juliana B. Taniguchi, Rafael G. B. Gomes, Benoit Lombardot
المساهمون: Inst Pasteur Korea, Univ Feevale, Universidade Federal de Uberlândia (UFU), Univ Estadual Rio Grande do Sul, Universidade Estadual Paulista (Unesp), Inst Pasteur, Institut Pasteur Korea - Institut Pasteur de Corée, Réseau International des Instituts Pasteur (RIIP), Universidade Federal de Uberlândia, Universidade Estadual do Rio Grande do Sul, Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University (UNESP), Virus et Immunité - Virus and immunity, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), The authors would like to acknowledge Katja Fink for the gift of HuH-7 cells and Claudia N. D. dos-Santos for the gift of C6/36 cells., Universidade Estadual do Rio Grande do Sul (UERGS), Virus et Immunité - Virus and immunity (CNRS-UMR3569), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2012, 7 (10), pp.e2471. ⟨10.1371/journal.pntd.0002471⟩
PLoS Neglected Tropical Diseases, 2012, 7 (10), pp.e2471. ⟨10.1371/journal.pntd.0002471⟩
PLoS Neglected Tropical Diseases, Vol 7, Iss 10, p e2471 (2013)مصطلحات موضوعية: MESH: Oxidation-Reduction, MESH: Cell Death, Cell, MESH: Chikungunya virus/physiology, chemistry.chemical_compound, MESH: Optical Imaging/methods, Cytopathic effect, MESH: Inhibitory Concentration 50, MESH: Alphavirus Infections/virology, 0303 health sciences, Cell Death, lcsh:Public aspects of medicine, Optical Imaging, MESH: Protein Kinase Inhibitors/isolation & purification, virus diseases, 3. Good health, MESH: Hepatocytes/drug effects, medicine.anatomical_structure, Infectious Diseases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, MESH: Antiviral Agents/isolation & purification, Chikungunya virus, Oxidation-Reduction, Research Article, Programmed cell death, lcsh:Arctic medicine. Tropical medicine, Cell Survival, lcsh:RC955-962, MESH: High-Throughput Screening Assays/methods, Biology, Antiviral Agents, Virus, Cell Line, MESH: Protein Kinase Inhibitors/pharmacology, 03 medical and health sciences, Inhibitory Concentration 50, Oxazines, medicine, Humans, Viability assay, Protein Kinase Inhibitors, 030304 developmental biology, MESH: Cell Survival/drug effectsm, MESH: Humans, Staining and Labeling, 030306 microbiology, Alphavirus Infections, Public Health, Environmental and Occupational Health, MESH: Hepatocytes/physiology, MESH: Xanthenes/metabolism, Resazurin, lcsh:RA1-1270, Virology, High-Throughput Screening Assays, MESH: Cell Line, chemistry, Xanthenes, Apoptosis, Cell culture, MESH: Alphavirus Infections/drug therapy, MESH: Hepatocytes/virology, Hepatocytes, MESH: Staining and Labeling/methods, MESH: Cell Survival/drug effects, MESH: Oxazines/metabolism
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المؤلفون: Christine Scheidig, Thomas E. Wellems, Ulf Nehrbass, Françoise Guinet, Lucio H. Freitas-Junior, Emmanuel Bottius, Kirk W. Deitsch, Artur Scherf, Lindsay A. Pirrit
المصدر: Nature. 407:1018-1022
مصطلحات موضوعية: Recombination, Genetic, Genetics, Multidisciplinary, Mitotic crossover, Base Sequence, Virulence, Genes, Protozoan, Molecular Sequence Data, Plasmodium falciparum, DNA, Protozoan, Telomere, Biology, Subtelomere, Antigenic Variation, Chromosomes, Antigenic variation, Animals, Gene family, Ectopic recombination, Gene conversion, Gene, In Situ Hybridization, Fluorescence
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المؤلفون: Kai Li, Hong Wang, Lucio H. Freitas-Junior, Craig T. Morita, Yonghui Zhang, Yi Liang Liu, Anmol Gulati, Joo Hwan No, Wei Zhu, Lawrence Ayong, Ke Wang, Eric Oldfield, Ran Pang
مصطلحات موضوعية: chemistry.chemical_classification, Membrane permeability, T cell, Organic Chemistry, Biology, Biochemistry, Isoprenoid biosynthesis, medicine.anatomical_structure, Farnesyl diphosphate synthase, Enzyme, chemistry, Drug Discovery, medicine, biology.protein, Parasite hosting, Transferase, Cell penetration
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c8da05ab25b5d20dde3592cdf02da8
https://europepmc.org/articles/PMC3630516/ -
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المؤلفون: Lucio H. Freitas-Junior, Michael Adsetts Edberg Hansen, Monica Contreras-Dominguez, Carolina B. Moraes, Thierry Dorval, Auguste Genovesio, Fernando de M. Dossin
المساهمون: Institut Pasteur Korea - Institut Pasteur de Corée, Réseau International des Instituts Pasteur (RIIP), Interdisciplinary Nanoscience Centre (iNANO), Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de biologie de l'ENS Paris (IBENS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de biologie de l'ENS Paris (UMR 8197/1024) (IBENS), Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (2), pp.e55539. ⟨10.1371/journal.pone.0055539⟩
PLoS ONE, Vol 8, Iss 2, p e55539 (2013)مصطلحات موضوعية: Transcription, Genetic, [SDV]Life Sciences [q-bio], Fluorescent Antibody Technique, lcsh:Medicine, Molecular cell biology, 0302 clinical medicine, Transcription (biology), Gene expression, lcsh:Science, Genetics, Regulation of gene expression, 0303 health sciences, Multidisciplinary, Gene Expression Regulation, Developmental, Chromatin, Cellular Structures, 3. Good health, Infectious Diseases, medicine.anatomical_structure, Medicine, Epigenetics, Research Article, DNA transcription, Plasmodium falciparum, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Microbiology, 03 medical and health sciences, parasitic diseases, Parasitic Diseases, medicine, Animals, Gene, Transcription factor, 030304 developmental biology, Cell Nucleus, Nucleoplasm, lcsh:R, Parasite Physiology, Computational Biology, Malaria, Cell Compartmentation, Cell nucleus, Parasitology, lcsh:Q, 030217 neurology & neurosurgery
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المؤلفون: Heechang Kim, Lawrence Ayong, Sukjun Lee, Seunghyun Moon, Myungjoo Kang, Lucio H. Freitas-Junior, Michael Adsetts Edberg Hansen
المساهمون: Institut Pasteur Korea - Institut Pasteur de Corée, Réseau International des Instituts Pasteur (RIIP), Department of Mathematics, Seoul National University [Seoul] (SNU), This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST)(No. 2012-00011), Gyeonggi-do and KISTI. Myungjoo Kang was supported by the Basic Science Research Program (2012-001766) through the National Research Foundation of Korea.
المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (4), pp.e61812. ⟨10.1371/journal.pone.0061812⟩
PLoS ONE, Vol 8, Iss 4, p e61812 (2013)
PLOS ONE(8): 4مصطلحات موضوعية: Erythrocytes, Indoles, Spores, Protozoan, Population Modeling, lcsh:Medicine, 02 engineering and technology, Plasmodium, chemistry.chemical_compound, [INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing, Chloroquine, Image Processing, Computer-Assisted, 0202 electrical engineering, electronic engineering, information engineering, Parasite hosting, Organic Chemicals, Artemisinin, lcsh:Science, Cells, Cultured, 0303 health sciences, education.field_of_study, Multidisciplinary, Artemisinins, Mitochondria, 3. Good health, Infectious Diseases, Medical Microbiology, Medicine, 020201 artificial intelligence & image processing, Algorithm, [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing, Algorithms, Research Article, medicine.drug, Infectious Disease Control, Cell Survival, Plasmodium falciparum, Population, Biology, Microbiology, Antimalarials, Inhibitory Concentration 50, 03 medical and health sciences, parasitic diseases, Parasitic Diseases, medicine, Humans, education, Fluorescent Dyes, 030304 developmental biology, lcsh:R, Computational Biology, medicine.disease, biology.organism_classification, Malaria, Multiple drug resistance, Microscopy, Fluorescence, chemistry, Computer Science, SYBR Green I, lcsh:Q, Infectious Disease Modeling, Mathematics
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المؤلفون: Hee-Young Kim, Claudia Nunes Duarte dos Santos, Lucio H. Freitas-Junior, Sungmin Baek, Rafaela Milan Bonotto, Michel Liuzzi, Joo Hwan No, Deu John M. Cruz, Marc P. Windisch, Ana Luiza Pamplona Mosimann, Michael Adsetts Edberg Hansen, Keum Hyun Kim, Xiaolan Li, Andrea Cristine Koishi, Luana de Borba, Juliana Bosso Taniguchi
المساهمون: Institut Pasteur Korea, Fundação Oswaldo Cruz Paraná (ICC/FIOCRUZ-PR), Universidade Federal do Paraná (UFPR), Universidade Estadual Paulista (Unesp), Universidade Feevale
المصدر: PLoS Neglected Tropical Diseases, Vol 7, Iss 2, p e2073 (2013)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
PLoS Neglected Tropical Diseasesمصطلحات موضوعية: Serotype, genotype, Chikungunya alphavirus, animal cell, Dengue virus, medicine.disease_cause, viral disease immunofluorescence assay, Dengue fever, chloroquine, computer program, dose response, Drug Discovery, Drug discovery, lcsh:Public aspects of medicine, Flavivirus, alpha2a interferon, Infectious Diseases, High-content screening, antiviral activity, Research Article, Biotechnology, lcsh:Arctic medicine. Tropical medicine, ribavirin, lcsh:RC955-962, phosphotransferase inhibitor, Microbial Sensitivity Tests, Biology, Microbiology, Antiviral Agents, peptide library, Cell Line, affinity chromatography, Virology, High-Throughput Screening Assays, medicine, Humans, controlled study, human, Peptide library, nonhuman, human cell, Public Health, Environmental and Occupational Health, nucleotide sequence, lcsh:RA1-1270, Dengue Virus, medicine.disease, biology.organism_classification, drug structure, validation process, Immunology, Hepatocytes, computer model, high throughput screening
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المؤلفون: Jinyoung Anny Yoo, Yi Liang Liu, Ke Wang, Wei Zhu, Xinxin Feng, Raymond Hui, Fernando de M. Dossin, Yonghui Zhang, Lucio H. Freitas-Junior, Joo Hwan No, Eric Oldfield, Eunhae Lee
مصطلحات موضوعية: Models, Molecular, Plasmodium, Erythrocytes, Plasmodium falciparum, Plasma protein binding, Pharmacology, Calorimetry, Crystallography, X-Ray, Parasitemia, Zoledronic Acid, Antimalarials, Mice, In vivo, Transferase, Animals, Farnesyltranstransferase, Humans, Enzyme Inhibitors, Multidisciplinary, biology, Diphosphonates, Terpenes, Imidazoles, Active site, Etidronic Acid, biology.organism_classification, Lipids, Survival Analysis, In vitro, High-Throughput Screening Assays, Risedronate Sodium, Biochemistry, Physical Sciences, biology.protein, Plasmodium vivax, Risedronic Acid, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4222db17f1dd130c80dfe8d0a407e252
https://europepmc.org/articles/PMC3306666/
