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81
المؤلفون: Samuel B. Luty, Richard D. Press, Anupriya Agarwal, Grover C. Bagby, Karl J. Aichberger, Heike L. Pahl, Richard T. Silver, Dorian LaTocha, Shirin Doratotaj, Kavin B. Vasudevan, Brian J. Druker, Marc M. Loriaux, Angela G. Fleischman, Thomas Bumm, Thomas O'Hare, Curtis L. Petersen, Fei Yang, Michael W. Deininger
المصدر: Blood. 118(24)
مصطلحات موضوعية: medicine.medical_treatment, Immunology, Bone Marrow Cells, Biochemistry, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Proinflammatory cytokine, Mice, Myeloproliferative Disorders, Cell Line, Tumor, medicine, Animals, Humans, Point Mutation, RNA, Messenger, Progenitor cell, Clonogenic assay, Protein Kinase Inhibitors, Cells, Cultured, Myeloid Progenitor Cells, Mice, Knockout, Janus kinase 2, biology, Tumor Necrosis Factor-alpha, Fanconi Anemia Complementation Group C Protein, Cell Biology, Hematology, Janus Kinase 2, Molecular biology, Recombinant Proteins, Gene Expression Regulation, Neoplastic, Cytokine, Cell Transformation, Neoplastic, Amino Acid Substitution, biology.protein, Leukocytes, Mononuclear, Tumor necrosis factor alpha, Mutant Proteins, Stem cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e77e6d2eaf40553a20db11d7c1d67d
https://pubmed.ncbi.nlm.nih.gov/22161849 -
82
المؤلفون: Katalin Kelemen, Richard D. Press, Ken Gatter, James Huang, Rita M. Braziel, Guang Fan, Marc M. Loriaux, Nicky Leeborg, Susan B. Olson, Jennifer Dunlap
المصدر: American journal of clinical pathology. 135(5)
مصطلحات موضوعية: medicine.medical_specialty, Pathology, Down syndrome, Chromosomes, Human, Pair 21, Chromosomes, Human, Pair 20, Chromosome 9, hemic and lymphatic diseases, medicine, Humans, Chromosome 7 (human), Chromosome Aberrations, Myeloproliferative Disorders, Chromosomes, Human, Pair 13, business.industry, Cytogenetics, food and beverages, Karyotype, General Medicine, Janus Kinase 2, medicine.disease, Myelodysplastic-Myeloproliferative Diseases, Cell Transformation, Neoplastic, Karyotyping, Mutation (genetic algorithm), Mutation, Chromosome abnormality, Disease Progression, business, Trisomy, Chromosomes, Human, Pair 9, hormones, hormone substitutes, and hormone antagonists, Chromosomes, Human, Pair 7
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3112ebddaad42b9d98fa2ad3a63e6a87
https://pubmed.ncbi.nlm.nih.gov/22431549 -
83
المؤلفون: Joseph M. Gozgit, Tim Clackson, Matthew J. Wong, Marc M. Loriaux, Victor M. Rivera, Jeffrey W. Tyner, Brian J. Druker, William C. Shakespeare, Qurish K. Mohemmad, Scott Wardwell, Narayana I. Narasimhan, Frank Wang
مصطلحات موضوعية: Cancer Research, Receptor, Platelet-Derived Growth Factor alpha, Apoptosis, Mice, SCID, Article, chemistry.chemical_compound, Mice, hemic and lymphatic diseases, Cell Line, Tumor, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 1, Phosphorylation, Receptor, IC50, Protein Kinase Inhibitors, Cell Proliferation, biology, Kinase, Fibroblast growth factor receptor 1, Ponatinib, Imidazoles, Myeloid leukemia, Receptor Protein-Tyrosine Kinases, Xenograft Model Antitumor Assays, Pyridazines, Leukemia, Myeloid, Acute, Proto-Oncogene Proteins c-kit, Oncology, chemistry, fms-Like Tyrosine Kinase 3, Hematologic Neoplasms, Cancer research, biology.protein, Female, Platelet-derived growth factor receptor, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53c5600938febc32e1d28752e778ef3
https://europepmc.org/articles/PMC3236248/ -
84
المؤلفون: Frederick S. Keller, Michael J. Conlin, Barry T. Uchida, Dusan Pavcnik, Josef Rösch, Young Hwan Kim, Hideyaki Kakizawa, Marc M. Loriaux
المصدر: Cardiovascular and interventional radiology. 33(3)
مصطلحات موضوعية: medicine.medical_specialty, Kidney Cortex, Swine, medicine.medical_treatment, Infarction, Biocompatible Materials, Pilot Projects, Nephroscopy, Radiography, Interventional, Kidney Calculi, Postoperative Complications, Occlusion, medicine, Animals, Radiology, Nuclear Medicine and imaging, Embolization, Intestinal Mucosa, Nephrostomy, Percutaneous, Kidney, Gastrointestinal tract, medicine.diagnostic_test, business.industry, Angiography, Endoscopy, medicine.disease, Small intestine, Surgery, medicine.anatomical_structure, Nephrostomy, Collagen, Cardiology and Cardiovascular Medicine, business
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المؤلفون: Michael W. Deininger, Stephanie G. Willis, Tibor Kovacsovics, Bill H. Chang, Thomas O'Hare, Heidi Erickson, Jeffrey W. Tyner, Jason Gotlib, Brian J. Druker, Marc M. Loriaux, Michael Heinrich
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 106(21)
مصطلحات موضوعية: Time Factors, medicine.medical_treatment, Targeted therapy, LYN, Cell Line, Tumor, medicine, Humans, Lemur tyrosine kinase 3, Alleles, Thrombopoietin receptor, Multidisciplinary, Janus kinase 2, Leukemia, biology, business.industry, Gene Expression Profiling, Janus Kinase 2, Biological Sciences, Gene expression profiling, Gene Expression Regulation, Neoplastic, Treatment Outcome, ROR1, Mutation, biology.protein, Cancer research, RNA Interference, Personalized medicine, business, Receptors, Thrombopoietin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4c5ca248630ef2ebee299ec7fbc29c
https://pubmed.ncbi.nlm.nih.gov/19433805 -
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المؤلفون: Brian J. Druker, Amie S. Corbin, Ian J. Griswold, Michael W. Deininger, Kara Johnson, Thomas O'Hare, Marc M. Loriaux
المصدر: PLoS ONE
PLoS ONE, Vol 4, Iss 10, p e7439 (2009)مصطلحات موضوعية: Pathology/Histopathology, Fusion Proteins, bcr-abl, lcsh:Medicine, Biology, SH2 domain, Cell Biology/Cell Signaling, 03 medical and health sciences, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, hemic and lymphatic diseases, STAT5 Transcription Factor, Oncology/Myeloproliferative Disorders, including Chronic Myeloid Leukemia, Animals, Proto-Oncogene Proteins c-cbl, Kinase activity, Phosphorylation, lcsh:Science, 030304 developmental biology, Adaptor Proteins, Signal Transducing, GRB2 Adaptor Protein, 0303 health sciences, Mice, Inbred BALB C, Multidisciplinary, Binding Sites, Leukemia, Hematology/Bone Marrow and Stem Cell Transplantation, lcsh:R, Signal transducing adaptor protein, Nuclear Proteins, Neoplasms, Experimental, Fusion protein, CRKL, Cell Transformation, Neoplastic, Hematology/Myeloproliferative Disorders, including Chronic Myeloid Leukemia, 030220 oncology & carcinogenesis, biology.protein, Cancer research, lcsh:Q, Female, Interleukin-3, GRB2, Signal transduction, Pathology/Hematology, Tyrosine kinase, Signal Transduction, Research Article
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المصدر: Journal of Biological Chemistry. 266:18431-18434
مصطلحات موضوعية: biology, p300-CBP coactivator family, viruses, fungi, genetic processes, Activating transcription factor, Cell Biology, CREB, environment and public health, Biochemistry, Molecular biology, ATF/CREB, Enhancer binding, Cyclic AMP Response Element-Binding Protein, biology.protein, CREB1, Protein kinase A, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c96a8bb99786edb2ba9549ca18ad4fa3
https://doi.org/10.1016/s0021-9258(18)55078-x -
88
المؤلفون: Ross L. Levine, Christopher A. Eide, Stephanie G. Willis, Heidi Erickson, Brian J. Druker, Jeffrey W. Tyner, Michael W. Deininger, Michael Heinrich, D. Gary Gilliland, Norbert Gattermann, Marc M. Loriaux
المصدر: Blood. 113(8)
مصطلحات موضوعية: Neuroblastoma RAS viral oncogene homolog, Immunology, Bone Marrow Cells, Biology, medicine.disease_cause, Biochemistry, Cell Line, Proto-Oncogene Proteins p21(ras), Mice, medicine, Animals, Humans, Point Mutation, HRAS, Genetic Testing, Genetics, Mutation, Mice, Inbred BALB C, Myeloid Neoplasia, Point mutation, Myeloid leukemia, Leukemia, Myelomonocytic, Chronic, Cell Biology, Hematology, Fibroblasts, medicine.disease, Leukemia, Leukemia, Myeloid, Acute, Cell Transformation, Neoplastic, Cancer research, KRAS, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95cd19b51bee3fc7b4c9d6c9254c7466
https://pubmed.ncbi.nlm.nih.gov/19075190 -
89
المؤلفون: Richard Stone, Stefan Fröhling, Heidi Erickson, Michael W. Deininger, Brian J. Druker, Jeffrey W. Tyner, Roland Berger, Gerlinde Wernig, James D. Griffin, Eric P. Stoffregen, D. Gary Gilliland, Christopher A. Eide, Matthew Meyerson, Olivier Bernard, Ross L. Levine, Claudia Scholl, Marc M. Loriaux, Michael Heinrich, Benjamin H. Lee
مصطلحات موضوعية: Genetics, Nonsynonymous substitution, Neoplasia, Sequence analysis, Immunology, Myeloid leukemia, Cell Biology, Hematology, Biology, Biochemistry, Molecular biology, Receptor tyrosine kinase, Fms-Like Tyrosine Kinase 3, biology.protein, Kinome, Tyrosine kinase, Gene
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e270da89592cdfaf2d1e486601518a1
https://europepmc.org/articles/PMC2343606/ -
90
المؤلفون: Jorge E. Cortes, Anupriya Agarwal, Amie S. Corbin, Michael W. Deininger, Brian J. Druker, Marc M. Loriaux
المصدر: The Journal of clinical investigation. 121(1)
مصطلحات موضوعية: Cell Survival, CD34, Fusion Proteins, bcr-abl, Antineoplastic Agents, CD38, In Vitro Techniques, Models, Biological, Piperazines, hemic and lymphatic diseases, Clinical investigation, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Medicine, Humans, Progenitor cell, neoplasms, Protein Kinase Inhibitors, Cell Proliferation, business.industry, Myeloid leukemia, Imatinib, General Medicine, medicine.disease, Leukemia, Imatinib mesylate, Pyrimidines, Drug Resistance, Neoplasm, Immunology, Benzamides, Imatinib Mesylate, Neoplastic Stem Cells, Cytokines, Erratum, Stem cell, business, Research Article, medicine.drug
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