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المؤلفون: Mark O. Collins, Jyoti S. Choudhary, Frank Schwach, David A. Baker, Oliver Billker, Mathieu Brochet, Sarah Sebastian, Eloise Thompson, Terry K. Smith, Julian C. Rayner, Katrin Volkmann, Lia Chappell, Ana Rita Gomes, Matthew Berriman
المصدر: PLoS Biology
مصطلحات موضوعية: Gliding motility, Pathogenesis, Signal transduction, Phosphatidylinositols, Molecular cell biology, Crosstalk, Second Messenger System, Calcium signaling, biology, Protein Kinase Signaling Cascade, Kinase, General Neuroscience, Mechanisms of Signal Transduction, Signaling Cascades, 3. Good health, Cell biology, Cyclic GMP-Dependent Protein Kinases, Host-Pathogen Interaction, Biochemistry, cardiovascular system, General Agricultural and Biological Sciences, Research Article, Signaling in cellular processes, Plasmodium falciparum, Phosphoinositide Signal Transduction, Microbiology, Signaling Pathways, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Host-Parasite Interactions, parasitic diseases, Calcium-Mediated Signal Transduction, Animals, Humans, Plasmodium berghei, Calcium Signaling, Protein kinase A, Biology, Life Cycle Stages, General Immunology and Microbiology, Parasite Physiology, biology.organism_classification, Malaria, Culicidae, Cell movement signaling, Phospholipid Signaling Cascade, Calcium Signaling Cascade, cGMP signaling, Parasitology, cGMP-dependent protein kinase
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المؤلفون: Panos Roussos, Steven A. McCarroll, Pamela Sklar, Stephen J. Haggarty, Eric Banks, Stacey Gabriel, Colm O'Dushlaine, Edward M. Scolnick, Mark O. Collins, Jyoti S. Choudhary, Menachem Fromer, Anna K. Kähler, Christina M. Hultman, Sarah E. Bergen, Shaun Purcell, Patrik K. E. Magnusson, Kiran V. Garimella, Esperanza Fernández, Seth G. N. Grant, Kimberly Chambert, Nadia Solovieff, Khalid Shakir, Laramie E. Duncan, Noboru H. Komiyama, Eric S. Lander, Eli A. Stahl, Timothy Fennell, Giulio Genovese, Douglas M. Ruderfer, Patrick F. Sullivan, Mark A. DePristo, Jennifer L. Moran
المساهمون: Massachusetts Institute of Technology. Department of Biology, Lander, Eric S.
المصدر: PMC
Nature
Nature; Vol 506مصطلحات موضوعية: Male, Multifactorial Inheritance, DNA Copy Number Variations, Population, Neurogenetics, Genome-wide association study, Nerve Tissue Proteins, Biology, Receptors, N-Methyl-D-Aspartate, Article, 03 medical and health sciences, Fragile X Mental Retardation Protein, 0302 clinical medicine, Intellectual Disability, Humans, Allele, Autistic Disorder, education, Exome, Exome sequencing, 030304 developmental biology, Genetic association, Genetics, 0303 health sciences, education.field_of_study, Multidisciplinary, Intracellular Signaling Peptides and Proteins, Membrane Proteins, FMR1, 3. Good health, Cytoskeletal Proteins, Mutation, Schizophrenia, Female, Calcium Channels, Disks Large Homolog 4 Protein, 030217 neurology & neurosurgery, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Seth G. N. Grant, Jyoti S. Choudhary, Mike D. R. Croning, Mark O. Collins, Àlex Bayés, Louie N. van de Lagemaat
المصدر: Bayes, A, Collins, M O, Croning, M D R, Van De Lagemaat, L, Choudhary, J S & Grant, S G N 2012, ' Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins ', PLoS ONE, vol. 7, no. 10, e46683, pp.-. https://doi.org/10.1371/journal.pone.0046683
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46683 (2012)
PLoS One
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Universitat Politècnica de Catalunya (UPC)
PLoS ONE; Vol 7مصطلحات موضوعية: Proteomics, Male, Proteome, lcsh:Medicine, Biochemistry, Synapse, Mice, 0302 clinical medicine, Postsynaptic potential, Tandem Mass Spectrometry, Protein Interaction Maps, lcsh:Science, Cerebral Cortex, Medicine(all), 0303 health sciences, Multidisciplinary, Agricultural and Biological Sciences(all), Proteomic Databases, Systems Biology, Signal transducing adaptor protein, Neurochemistry, Animal Models, Cell biology, Excitatory postsynaptic potential, Chromatography, Gel, Medicine, Female, Research Article, Evolutionary Processes, Mice, 129 Strain, Microtubule-associated protein, Clinical Research Design, Nerve Tissue Proteins, Biology, 03 medical and health sciences, Model Organisms, Species Specificity, Neurotransmitter receptor, Centrifugation, Density Gradient, Animals, Humans, Animal Models of Disease, 030304 developmental biology, Evolutionary Biology, Biochemistry, Genetics and Molecular Biology(all), lcsh:R, Proteins, Computational Biology, Post-Synaptic Density, Synapses, lcsh:Q, Molecular Neuroscience, Postsynaptic density, 030217 neurology & neurosurgery, Protein Abundance, Synaptic Plasticity, Neuroscience
وصف الملف: application/pdf
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المؤلفون: Aoife McMahon, Jyoti S. Choudhary, Mark W. Barnett, Giles E. Hardingham, Noboru H. Komiyama, Timothy O'Leary, Sofia Papadia, Peter C. Kind, David J. A. Wyllie, P N Stoney, Mark O. Collins, Seth G. N. Grant
المساهمون: O'Leary, Timothy [0000-0002-1029-0158], Papadia, Sofia [0000-0002-9222-3812], Apollo - University of Cambridge Repository
المصدر: Nature Communications
Nature Communications; Vol 3
McMahon, A C, Barnett, M W, O'Leary, T S, Stoney, P N, Collins, M O, Papadia, S, Choudhary, J S, Komiyama, N H, Grant, S G N, Hardingham, G E, Wyllie, D J A & Kind, P C 2012, ' SynGAP isoforms exert opposing effects on synaptic strength ', Nature Communications, vol. 3, 900 . https://doi.org/10.1038/ncomms1900مصطلحات موضوعية: Gene isoform, Chemistry(all), Molecular Sequence Data, General Physics and Astronomy, Physics and Astronomy(all), Biology, SYNGAP1, Hippocampus, Mass Spectrometry, Article, General Biochemistry, Genetics and Molecular Biology, Primer extension, Mice, 03 medical and health sciences, 0302 clinical medicine, Rapid amplification of cDNA ends, Animals, Protein Isoforms, Amino Acid Sequence, Peptide sequence, 030304 developmental biology, Neurons, Genetics, 0303 health sciences, Multidisciplinary, Biochemistry, Genetics and Molecular Biology(all), Alternative splicing, General Chemistry, Cell biology, Electrophysiology, Mice, Inbred C57BL, ras GTPase-Activating Proteins, Synapses, Synaptic plasticity, Excitatory postsynaptic potential, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Lu Yu, Lukas Käll, Mark O. Collins, James C. Wright, Markus Brosch, Jyoti S. Choudhary
المصدر: Molecular & Cellular Proteomics : MCP
مصطلحات موضوعية: Proteomics, Collision-induced dissociation, Computational biology, Mass spectrometry, Tandem mass spectrometry, Biochemistry, Analytical Chemistry, Fungal Proteins, 03 medical and health sciences, Mascot, Fragmentation (mass spectrometry), Artificial Intelligence, Tandem Mass Spectrometry, Yeasts, Escherichia coli, Humans, Database search engine, Databases, Protein, Molecular Biology, 030304 developmental biology, 0303 health sciences, Fungal protein, Chromatography, Chemistry, Escherichia coli Proteins, 030302 biochemistry & molecular biology, Technological Innovation and Resources, Reproducibility of Results, Electron-transfer dissociation, Peptides, Algorithms, Software, Chromatography, Liquid
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9580f3e7e10761f5412a5e20f63a620e
https://pubmed.ncbi.nlm.nih.gov/22493177 -
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المؤلفون: Michael Conlon O'Donovan, Jyoti S. Choudhary, Rebecca Louise Wollerton, Seth G. N. Grant, Kimberly Chambert, Esperanza Fernández, Douglas M. Ruderfer, Dobril Ivanov, L N van de Lagemaat, Michael John Owen, Lyudmila Georgieva, Marija Fjodorova, George Kirov, Àlex Bayés, Pamela Sklar, Shaun Purcell, Mark O. Collins, Jennifer L. Moran, Draga Toncheva, Masashi Ikeda, Hreinn Stefansson, Pall I. Olason, Noboru H. Komiyama, Ivan Nikolov, Elliott Rees, Detelina Grozeva, Peter Holmans, Andrew Pocklington, Yvonne Böttcher, Kari Stefansson
المساهمون: [ 1 ] Cardiff Univ, Dept Psychol Med & Neurol, Sch Med, MRC Ctr Neuropsychiat Genet & Genoom,Neurosci & M, Cardiff CF14 4XN, S Glam, Wales [ 2 ] Fujita Hlth Univ, Sch Med, Dept Psychiat, Toyoake, Aichi 47011, Japan [ 3 ] Massachusetts Gen Hosp, Dept Psychiat, Psychiat & Neurodev Genet Unit, Boston, MA 02114 USA [ 4 ] Harvard Univ, Sch Med, Boston, MA USA [ 5 ] Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA [ 6 ] Broad Inst, Stanley Ctr Psychiat Res, Cambridge, MA USA [ 7 ] Univ Hosp Maichin Dom, Sofia, Bulgaria [ 8 ] Univ Edinburgh, Genes Cognit Program, Sch Mol & Clin Med, Edinburgh, Midlothian, Scotland [ 9 ] KU Leuven Med Sch, VIB Dept Mol & Dev Genet, Louvain, Belgium [ 10 ] deCODE Genet, Reykjavik, Iceland [ 11 ] Wellcome Trust Sanger Inst, Hinxton, Cambs, England
المصدر: Molecular Psychiatry
Kirov, G, Pocklington, A J, Holmans, P, Ivanov, D, Ikeda, M, Ruderfer, D, Moran, J, Chambert, K, Toncheva, D, Georgieva, L, Grozeva, D, Fjodorova, M, Wollerton, R, Rees, E, Nikolov, I, Van De Lagemaat, L, Bayés, A, Fernandez, E, Olason, P I, Böttcher, Y, Komiyama, N H, Collins, M O, Choudhary, J, Stefansson, K, Stefansson, H, Grant, S G N, Purcell, S, Sklar, P, O'Donovan, M C & Owen, M J 2012, ' De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia ', Molecular Psychiatry, vol. 17, no. 2, pp. 142-153 . https://doi.org/10.1038/mp.2011.154
Molecular Psychiatry; Vol 17مصطلحات موضوعية: Male, Iceland, 0302 clinical medicine, Gene Frequency, Japan, AIDS-Related Complex, Gene duplication, Copy-number variation, Bulgaria, Genetics, 0303 health sciences, education.field_of_study, EHMT1, Arc (protein), 3. Good health, Psychiatry and Mental health, DLG, Female, Signal Transduction, de novo, congenital, hereditary, and neonatal diseases and abnormalities, DNA Copy Number Variations, Genotype, CNV, Population, Biology, Models, Biological, Receptors, N-Methyl-D-Aspartate, postsynaptic, Statistics, Nonparametric, 03 medical and health sciences, Cellular and Molecular Neuroscience, Geðklofi, Meta-Analysis as Topic, mental disorders, Humans, Genetic Predisposition to Disease, education, Molecular Biology, Allele frequency, 030304 developmental biology, Family Health, Psychiatric Status Rating Scales, Microarray analysis techniques, Post-Synaptic Density, Arfgengi, Microarray Analysis, schizophrenia, Case-Control Studies, Synapses, Schizophrenia, RC0321, Immediate Communication, Postsynaptic density, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المصدر: Nature cell biology
ResearcherIDمصطلحات موضوعية: Time Factors, Cdc20 Proteins, Ubiquitin-Protein Ligases, Mitosis, Cell Cycle Proteins, CDC20, Spindle Apparatus, Biology, Transfection, Anaphase-Promoting Complex-Cyclosome, Article, 03 medical and health sciences, 0302 clinical medicine, Chromosome Segregation, Mad2 Proteins, Humans, Cyclin B1, Kinetochores, 030304 developmental biology, 0303 health sciences, Kinetochore, Calcium-Binding Proteins, Ubiquitination, Mitotic checkpoint complex, Ubiquitin-Protein Ligase Complexes, Cell Biology, 3. Good health, Spindle apparatus, Cell biology, Repressor Proteins, Spindle checkpoint, M Phase Cell Cycle Checkpoints, RNA Interference, 030217 neurology & neurosurgery, HeLa Cells, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Jyoti S. Choudhary, Ian R. Whittle, Àlex Bayés, Mark O. Collins, Seth G. N. Grant, Mike D. R. Croning, Louie N. van de Lagemaat
المصدر: Bayes, A, Van De Lagemaat, L, Collins, M O, Croning, M D R, Whittle, I R, Choudhary, J S & Grant, S G N 2011, ' Characterization of the proteome, diseases and evolution of the human postsynaptic density ', Nature Neuroscience, vol. 14, no. 1, pp. 19-21 . https://doi.org/10.1038/nn.2719
Nature neuroscienceمصطلحات موضوعية: Pan troglodytes, Proteome, Neuroscience(all), Neocortex, Nerve Tissue Proteins, Biology, Proteomics, Article, Evolution, Molecular, 03 medical and health sciences, Mice, 0302 clinical medicine, Species Specificity, Nervous system disease, Central Nervous System Diseases, medicine, Animals, Humans, Gene, 030304 developmental biology, 0303 health sciences, General Neuroscience, Post-Synaptic Density, medicine.disease, Phenotype, Rats, medicine.anatomical_structure, Mutation, Macaca, Neuroscience, Postsynaptic density, 030217 neurology & neurosurgery, Function (biology)
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3a2209c34fd209821f7610db75acb8
https://www.pure.ed.ac.uk/ws/files/8477079/Characterization_of_the_proteome_diseases_and_evolution_of_the_human_postsynaptic_density.pdf -
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المؤلفون: Mark O. Collins, Agata Lichawska, Philip Zegerman, Felicia Walton Pagliuca, Jonathon Pines, Jyoti S. Choudhary
المصدر: Molecular cell. 43(3)
مصطلحات موضوعية: DNA Replication, Proteomics, Quantitative proteomics, Cyclin A, Molecular Sequence Data, Cell Cycle Proteins, Biology, Mass Spectrometry, Article, Protein–protein interaction, Cell Line, Substrate Specificity, 03 medical and health sciences, 0302 clinical medicine, Cyclin E, Humans, Immunoprecipitation, Amino Acid Sequence, Cyclin B1, Phosphorylation, Molecular Biology, Mitosis, 030304 developmental biology, Cyclin, Oncogene Proteins, 0303 health sciences, Cell Cycle, DNA replication, Nuclear Proteins, Cell Biology, Cell cycle, Protein-Tyrosine Kinases, Cyclin-Dependent Kinases, Cell biology, Wee1, biology.protein, Cyclin A2, Sequence Alignment, 030217 neurology & neurosurgery, HeLa Cells
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المؤلفون: Mark O, Collins
المصدر: Science (New York, N.Y.). 325(5948)
مصطلحات موضوعية: Threonine, Protein Folding, Binding Sites, Fungi, Proteins, Protein Serine-Threonine Kinases, Protein-Tyrosine Kinases, environment and public health, Biological Evolution, Article, Protein Structure, Tertiary, Evolution, Molecular, enzymes and coenzymes (carbohydrates), CDC2 Protein Kinase, Serine, Animals, Tyrosine, Phosphorylation, Protein Binding, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::257f84a78c43cc781b097d35cf9b2fe2
https://pubmed.ncbi.nlm.nih.gov/19779198
