يعرض 1 - 10 نتائج من 288 نتيجة بحث عن '"Nielsen-Kudsk JE"', وقت الاستعلام: 0.78s تنقيح النتائج
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    دورية أكاديمية
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    دورية أكاديمية

    المصدر: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 14(5):590-597

    مصطلحات موضوعية: Medicin och hälsovetenskap

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    دورية أكاديمية
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    دورية أكاديمية

    المصدر: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 16(5):626-630

    مصطلحات موضوعية: Medicin och hälsovetenskap

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    الوصف: This record contains raw data related to the article “Left atrial appendage occlusion with the Amplatzer™ Amulet™ device: full results of the prospective global observational study" Abstract Aims:To evaluate the safety and efficacy of left atrial appendage occlusion (LAAO) with the Amplatzer™ Amulet™ occluder. Methods and results:Patients with atrial fibrillation eligible for LAAO were recruited to a prospective global study. Implant procedures were undertaken with echocardiographic guidance. Transoesophageal echocardiography (TOE) was undertaken 1-3 months post-LAAO. Implant and follow-up TOEs were evaluated by a CoreLab. The primary endpoint was a composite of ischaemic stroke and cardiovascular death at 2 years. Serious adverse events were adjudicated by an independent clinical events committee. A total of 1088 patients were enrolled, aged 75.2 ± 8.5 years; 64.5% were male. CHA2DS2-VASc and HAS-BLED scores were 4.2 ± 1.6 and 3.3 ± 1.1, respectively. A total of 71.7% had prior major bleeding, and 82.8% had contraindications to oral anticoagulants. Implant success was 99.1%. Major adverse events (≤7 days post-procedure) occurred in 4.0%, including death (0.3%), stroke (0.4%), major vascular (1.3%), and device embolization (0.2%). A total of 80.2% of patients were discharged on antiplatelet therapy alone. Peridevice flow was Conclusion:Following LAAO with the Amplatzer Amulet device, the ischaemic stroke rate was reduced by 67% compared to the predicted risk. Closure was complete in 98.4% of cases and DRT seen in only 1.6%. Keywords:Antithrombotic treatment; Bleeding; Death; LAA closure; Stroke.