المؤلفون: Agrati, P, Ma, ZQ, Patrone, C, Picotti, GB, Pellicciari, C, Bondiolotti, G, Bottone, MG, Maggi, A

المصدر: EUROPEAN JOURNAL OF NEUROSCIENCE. 9(7):1552-1552

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:114754295

المؤلفون: Ulrich Binswanger, Jürg W. Blum, W. Hunziker, Picotti Gb, Da Prada M, A. Guillebeau, Jan A. Fischer

المصدر: Journal of Clinical Investigation. 61:1113-1122

مصطلحات موضوعية: Blood Glucose, endocrine system, medicine.medical_specialty, Epinephrine, chemistry.chemical_element, Parathyroid hormone, Blood Pressure, Propranolol, Fatty Acids, Nonesterified, Calcium, chemistry.chemical_compound, Heart Rate, Internal medicine, medicine, Extracellular, Animals, skin and connective tissue diseases, Egtazic Acid, Hypocalcemia, Isoproterenol, Articles, General Medicine, Plasma levels, EGTA, Endocrinology, chemistry, Parathyroid Hormone, Cattle, Female, sense organs, hormones, hormone substitutes, and hormone antagonists, Hormone, medicine.drug

الوصف: Modifications of the plasma level of immunoreactive parathyroid hormone (PTH) in cattle were induced by changes of the plasma concentrations of epinephrine, isoproterenol, or calcium. During abrupt hypocalcemia, PTH, obtained by infusions with ethylene glycol-bis (β-aminoethylether) N, N′-tetraacetate (EGTA), increased during the first 4-8 min. After a transient decline, the hormone levels rose again and remained elevated. Infusions of calcium suppressed the hypocalcemia-induced augmentation of PTH levels within a few minutes. Prolonged epinephrine (and isoproterenol) infusions also rapidly increased PTH levels, however, in this case, they returned to basal concentrations after 50-60 min. Additional epinephrine infusions could not further raise PTH values. Moreover, three short-lasting infusions of epinephrine (7 min each), given at 30-min intervals, increased PTH levels to the same extent, whereas additional infusions were much less effective. The PTH response to epinephrine was completely restored, when the interval after a prolonged epinephrine infusion had been prolonged to > 100 min. During moderate hypocalcemia, occurring at the end of EGTA infusions and lasting for 90 min, the PTH response to a short-lasting epinephrine infusion (7 min) was more pronounced than in normocalcemic animals. During severe hypocalcemia, in which superimposed short-lasting infusions of EGTA (7 min) led to an additional abrupt fall of plasma calcium concentrations but not to a corresponding additional rise of the PTH levels, epinephrine rapidly and further increased PTH concentrations. On the other hand, at the end of prolonged infusions of epinephrine, when additional infusions of epinephrine were ineffective in raising PTH levels, EGTA-induced hypocalcemia consistently increased PTH concentrations. The EGTA-induced augmentation of PTH levels was enhanced by epinephrine and isoproterenol but not by propranolol. The present findings indicate, that variations of the extracellular calcium concentrations and β-adrenergic agonists modify PTH levels by two different and independent mechanisms. On the other hand, it appears that the magnitude of change of the PTH levels to either stimulus is partially modulated by exposure to the other.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810b1b6c555a7b13d218ca56b182da95
https://doi.org/10.1172/jci109026

المؤلفون: Caviezel F, Picotti GB, Slaviero G, Galva MD, Camagna P, Bondiolotti GP, Carruba MO, Pozza G., MARGONATO , ALBERTO

المساهمون: Caviezel, F, Picotti, Gb, Margonato, Alberto, Slaviero, G, Galva, Md, Camagna, P, Bondiolotti, Gp, Carruba, Mo, Pozza, G.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_____10495::d32dce6c7761f9bd5736cdf04f5f981d

المؤلفون: Cannella, G., Picotti, Gb, Giambelli, A., Scolari, Francesco, Cesura, Am, Tosoni, S., Maiorca, Rosario

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3662::3920d0a3ed89313a4b5f5e29bd9f010a
http://hdl.handle.net/11379/159355

المؤلفون: Cannella, G, Picotti, Gb, Scolari, Francesco, Cancarini, Giovanni, Ravazzani, C, Cristinelli, L, Maiorca, Rosario

مصطلحات موضوعية: plasma catecholamines, hemodialysis, catecolamine plasmatiche, ultrafiltration, ultrafiltrazione, emdoialisi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3662::ceaf9651732f43a57a2437518bd3dfac
http://hdl.handle.net/11379/7647

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