يعرض 41 - 50 نتائج من 73 نتيجة بحث عن '"Pulmonary Disease, Chronic Obstructive complications"', وقت الاستعلام: 1.68s تنقيح النتائج
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    المؤلفون: Sérgio Saldanha Menna-Barreto

    المصدر: Repositório Institucional da UFRGS
    Universidade Federal do Rio Grande do Sul (UFRGS)
    instacron:UFRGS
    Jornal Brasileiro de Pneumologia v.31 n.6 2005
    Jornal Brasileiro de Pneumologia
    Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)
    instacron:SBPT

    الوصف: Tromboembolia pulmonar aguda e exacerbação aguda de doença pulmonar obstrutiva crônica são doenças comuns. A doença pulmonar obstrutiva crônica é um fator clínico de risco para tromboembolia pulmonar aguda. As apresentações clínicas da tromboembolia pulmonar aguda e da exacerbação aguda da doença pulmonar obstrutiva crônica freqüentemente mimetizamse tanto que pode ser difícil distingui-las. Anormalidades estruturais nos pulmões com doença pulmonar obstrutiva crônica tornam também difícil a interpretação de testes não invasivos de diagnóstico, como o mapeamento de ventilação e perfusão pulmonares. Assim, diagnosticar tromboembolia pulmonar aguda em pacientes com doença pulmonar obstrutiva crônica é uma tarefa desafiadora. Com o objetivo de atualizar o assunto e oferecer sugestões de conduta, nós avaliamos artigos abordando este tema, incluindo relatos e séries de casos, abordagens diagnósticas de tromboembolia pulmonar aguda e fizemos algumas reflexões. A probabilidade clínica de tromboembolia pulmonar aguda em cenários de doença pulmonar obstrutiva crônica é usualmente intermediária, o mapeamento de ventilação e perfusão pulmonares é predominantemente de probabilidade intermediária e os algoritmos de conduta os deveriam assim considerar. Pulmonary thromboembolism and exacerbation of chronic obstructive pulmonary disease are common conditions. Chronic obstructive pulmonary disease is a clinical risk factor for pulmonary thromboembolism. The presentation of acute pulmonary thromboembolism and acute exacerbation of chronic obstructive pulmonary disease often mimic each other so closely that they cannot be distinguished clinically. The structural abnormalities of the lungs in chronic obstructive pulmonary disease make also difficult to interpret the results of noninvasive tests like ventilation-perfusion lung scans. Therefore, diagnosing acute pulmonary thromboembolism in patients with underlying chronic obstructive pulmonary disease is a challenging task. In order to update knowledge of the subject and offer suggestions regarding conduct, we evaluated various studies addressing this theme, including case reports and case series. In addition, we reviewed diagnostic approaches to acute pulmonary thromboembolism, and we reflect upon that topic. The clinical probability of pulmonary thromboembolism concomitant to chronic obstructive pulmonary disease is typically intermediate, as is positivity on the ventilation-perfusion lung scan. Diagnostic algorithms should take that into consideration.

    وصف الملف: application/pdf; text/html

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  6. 46

    المساهمون: Pharmaceutical and Pharmacological Sciences, Pulmonary Medicine

    المصدر: Europe PubMed Central
    British Journal of Clinical Pharmacology, 77(5), 756-766. Wiley-Blackwell Publishing Ltd

    الوصف: AIMS: Few well-designed randomized controlled trials have been conducted regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with chronic obstructive pulmonary disease (COPD). We assessed the effectiveness of a pharmaceutical care programme for patients with COPD. METHODS: The pharmaceutical care for patients with COPD (PHARMACOP) trial is a single-blind 3 month randomized controlled trial, conducted in 170 community pharmacies in Belgium, enrolling patients prescribed daily COPD medication, aged ≥ 50 years and with a smoking history of ≥ 10 pack-years. A computer-generated randomization sequence allocated patients to an intervention group (n = 371), receiving protocol-defined pharmacist care, or a control group (n = 363), receiving usual pharmacist care (1:1 ratio, stratified by centre). Interventions focusing on inhalation technique and adherence to maintenance therapy were carried out at start of the trial and at 1 month follow-up. Primary outcomes wereinhalation technique and medication adherence. Secondary outcomes were exacerbation rate, dyspnoea, COPD-specific and generic health status and smoking behaviour. RESULTS: From December 2010 to April 2011, 734 patients were enrolled. Forty-two patients (5.7%) were lost to follow-up. At the end of the trial, inhalation score [mean estimated difference (Δ),13.5%; 95% confidence interval (CI), 10.8-16.1; P < 0.0001] and medication adherence (Δ, 8.51%; 95% CI, 4.63-12.4; P < 0.0001) were significantly higher in the intervention group compared with the control group. In the intervention group, a significantly lower hospitalization rate was observed (9 vs. 35; rate ratio, 0.28; 95% CI, 0.12-0.64; P = 0.003). No other significant between-group differences were observed. CONCLUSIONS: Pragmatic pharmacist care programmes improve the pharmacotherapeutic regimen in patients with COPD and could reduce hospitalization rates.

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    المصدر: University of Southern Denmark
    Fogh-Andersen, I S, Farver-Vestergaard, I, Pedersen, C M, Tehrani, E S & Løkke Ottesen, A 2022, ' Udredning og behandling af angst og depression hos patienter med KOL ', Ugeskrift for Laeger, bind 184, nr. 1, V09200679 . < https://ugeskriftet.dk/videnskab/udredning-og-behandling-af-angst-og-depression-hos-patienter-med-kol >
    Fogh-Andersen, I S, Farver-Vestergaard, I, Pedersen, C M, Tehrani, E & Ottesen, A L 2021, ' Udredning og behandling af angst og depression hos patienter med KOL ', Ugeskrift for Læger, bind 183, nr. 4, V09200679 . < https://ugeskriftet.dk/videnskab/udredning-og-behandling-af-angst-og-depression-hos-patienter-med-kol >

    الوصف: An estimated 33 percent of patients with COPD have co-morbidities in terms of anxiety and/or depression (A and D). A large proportion of these patients are not diagnosed, mainly because some of the core symptoms of A and D can be misinterpreted as being caused by COPD. Untreated A and D in patients with COPD can have a negative impact on several parameters e.g. dyspnoea and mortality. On this basis, this review argues, that special focus in primary care and hospitals on diagnosing and treating A and D in patients with COPD using anti-depressants or cognitive therapy can reduce symptom burden and significantly improve quality of life.

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