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المؤلفون: John Rickard, Kevin Jackson, Michael Gold, Mauro Biffi, Matteo Ziacchi, Joshua Silverstein, Brian Ramza, Mark Metzl, Eric Grubman, Richard Abben, Niraj Varma, Ghiyath Tabbal, Cory Jensen, Griet Wouters, Subham Ghosh, Kevin Vernooy
المساهمون: MUMC+: MA Cardiologie (3), Cardiologie, RS: Carim - H06 Electro mechanics, RS: Carim - H01 Clinical atrial fibrillation
المصدر: Heart Rhythm, 20, 537-544. Elsevier Science
مصطلحات موضوعية: Physiology (medical), Cardiology and Cardiovascular Medicine
الوصف: Background: Patients with ischemic cardiomyopathy, non–left bundle branch block, or QRS duration
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المؤلفون: Paul, Friedman, Francis, Murgatroyd, Lucas V A, Boersma, Jaimie, Manlucu, David, O'Donnell, Bradley P, Knight, Nicolas, Clémenty, Christophe, Leclercq, Anish, Amin, Béla P, Merkely, Ulrika M, Birgersdotter-Green, Joseph Y S, Chan, Mauro, Biffi, Reinoud E, Knops, Greg, Engel, Ignacio, Muñoz Carvajal, Laurence M, Epstein, Venkata, Sagi, Jens B, Johansen, Maciej, Sterliński, Clemens, Steinwender, Troy, Hounshell, Richard, Abben, Amy E, Thompson, Christopher, Wiggenhorn, Sarah, Willey, Ian, Crozier, Sergio, Thal
المساهمون: Cardiology, ACS - Heart failure & arrhythmias
المصدر: The New England journal of medicine, 387(14), 1292-1302. Massachussetts Medical Society
مصطلحات موضوعية: Treatment Outcome, Electric Countershock, Humans, Arrhythmias, Cardiac, General Medicine, Prospective Studies, Defibrillators, Implantable
الوصف: BACKGROUND: The extravascular implantable cardioverter-defibrillator (ICD) has a single lead implanted substernally to enable pause-prevention pacing, antitachycardia pacing, and defibrillation energy similar to that of transvenous ICDs. The safety and efficacy of extravascular ICDs are not yet known. METHODS: We conducted a prospective, single-group, nonrandomized, premarket global clinical study involving patients with a class I or IIa indication for an ICD, all of whom received an extravascular ICD system. The primary efficacy end point was successful defibrillation at implantation. The efficacy objective would be met if the lower boundary of the one-sided 97.5% confidence interval for the percentage of patients with successful defibrillation was greater than 88%. The primary safety end point was freedom from major system- or procedure-related complications at 6 months. The safety objective would be met if the lower boundary of the one-sided 97.5% confidence interval for the percentage of patients free from such complications was greater than 79%. RESULTS: A total of 356 patients were enrolled, 316 of whom had an implantation attempt. Among the 302 patients in whom ventricular arrhythmia could be induced and who completed the defibrillation testing protocol, the percentage of patients with successful defibrillation was 98.7% (lower boundary of the one-sided 97.5% confidence interval [CI], 96.6%; P
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المؤلفون: Richard Abben
المصدر: Journal of Innovations in Cardiac Rhythm Management. 7:2300-2302
مصطلحات موضوعية: Proarrhythmia, business.industry, Physiology (medical), media_common.quotation_subject, medicine, Appetite, Propafenone, Pharmacology, Cardiology and Cardiovascular Medicine, medicine.disease, business, media_common, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48c5d4bd0f5571875f786918dff029bf
https://doi.org/10.19102/icrm.2016.070303 -
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المؤلفون: Ravindra, Sharma, William, Ladd, Gary, Chaisson, Richard, Abben
المصدر: Circulation. 105(13)
مصطلحات موضوعية: Male, Occupational Diseases, Peripheral Vascular Diseases, Radiography, Ulnar Artery, Ischemia, Humans, Syndrome, Middle Aged, Hand
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5d5fad7458242cb92b08213bfda257a4
https://pubmed.ncbi.nlm.nih.gov/11927532 -
5
المؤلفون: Kenneth M. Rosen, Pablo Denes, Richard Abben
المصدر: Chest. 75:575-578
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Left bundle branch block, business.industry, Internal medicine, medicine, Cardiology, Complete LBBB, Myocardial infarction, Cardiology and Cardiovascular Medicine, Critical Care and Intensive Care Medicine, medicine.disease, business
الوصف: In an attempt to elucidate the specificity and sensitivity of atypical findings during left bundle branch block (LBBB) with respect to myocardial infarction (MI), we analyzed ECGs from patients with intermittent LBBB obtained by mail solicitation of cardiologists. The group consisted of 256 patient files fulfilling the following criteria: 1) complete LBBB present on one or more 12-lead ECGs, and 2) at least one 12-lead ECG taken subsequent to a LBBB tracing exhibiting absence of LBBB (non-LBBB). The sensitivity of atypical LBBB for predicting presence of MI was 0.41, the specificity 0.64, and the accuracy 0.59. No specific atypical finding was significantly better than any other in predicting MI. We conclude that atypical findings present during LBBB are of little value in predicting the presence of MI (as diagnosed by significant Q waves present during non-LBBB conduction).
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::de58d7a629a2cdff42a4ccf2f254ad0b
https://doi.org/10.1378/chest.75.5.575 -
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المؤلفون: Steven Swiryn, Kenneth M. Rosen, Richard Abben, Pablo Denes
المصدر: The American journal of cardiology. 46(1)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, Bundle-Branch Block, Myocardial Infarction, Cardiomegaly, Left ventricular hypertrophy, Standard deviation, QRS complex, Electrocardiography, Heart Conduction System, Internal medicine, Heart Septum, Medicine, Humans, Myocardial infarction, Child, Aged, medicine.diagnostic_test, business.industry, Left bundle branch block, Infant, Middle Aged, medicine.disease, Coronal plane, Child, Preschool, Cardiology, Left axis deviation, Female, Cardiology and Cardiovascular Medicine, business
الوصف: The frontal plane QRS axis of electrocardiograms during “normal” conduction and left bundle branch block were compared in 231 patients with intermittent left bundle branch block. The QRS axis during left bundle branch block ranged from +85 ° to −70 ° (mean ± standard deviation −7 ± 34 °), 79 patients (34 percent) having left axis deviation (QRS axis −30 ° or less). The QRS axis during “normal” conduction ranged from +90 ° to −75 ° (19 ± 34 °), 26 patients (11 percent) having left axis deviation. Regression analysis of the QRS axis during left bundle branch block versus “normal” conduction revealed the correlation coefficient (r) = 0.25 (p < 0.001). Of 26 patients with left axis deviation during normal conduction, 18 (70 percent) had left axis deviation during left bundle branch block (p < 0.001). Of 79 patients with left axis deviation during left bundle branch block, 61 (77 percent) did not have underlying left axis deviation during “normal” conduction. There was no significant association of axis during left bundle branch block with myocardial infarction or left ventricular hypertrophy diagnosed during “normal” conduction. In summary, although a small but significant correlation was found between the QRS axis during left bundle branch block and “normal” conduction, underlying left anterior hemiblock does not account for the presence of left axis deviation during left bundle branch block in most patients.
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المؤلفون: J D Garnic, Richard Abben, Peter Ganz, David C. Levin, Peter L. Friedman, Lawrence M. Boxt
المصدر: Radiology. 155(2)
مصطلحات موضوعية: Percutaneous transluminal coronary angioplasty, medicine.medical_specialty, business.industry, Technical success, Balloon catheter, Coronary Disease, Coronary Angiography, Coronary Vessels, Surgery, Catheter, Blunt, Bypass surgery, Coaxial catheter, medicine, Humans, Radiology, Nuclear Medicine and imaging, Radiology, business, Angioplasty, Balloon
الوصف: The original Gruentzig coaxial catheter system for percutaneous transluminal coronary angioplasty (PTCA) utilized a blunt, closed-end, inner balloon catheter with a short guide wire attached to its tip. Options for safely crossing severe stenoses with this large, nonmaneuverable catheter were limited. More recently, over-the-wire systems have been developed in which the lesion initially is crossed with a small-caliber floppy or steerable guide wire, then by the balloon catheter advanced over the wire. Technical success was achieved in 78 of our first 100 PTCAs with this system. Significant cardiac complications occurred in ten patients, seven of whom required emergency coronary bypass surgery. A recently published survey of all PTCA techniques reported a technical success rate of 62%. Our higher success rate may be attributed to certain advantages of the over-the-wire system, which are discussed in detail. A learning curve is associated with this procedure: our success rate was 65% in the first 20 cases but 81% thereafter. These results can be considered typical of those expected at hospitals now beginning PTCA programs with advanced over-the-wire technology.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe05d9b46e88b9ecaef46ff0b741587
https://pubmed.ncbi.nlm.nih.gov/3157203 -
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المؤلفون: David C. Levin, Peter L. Friedman, J.Daniel Garnic, William H. Barry, Peter Ganz, Richard Abben
المصدر: The American journal of cardiology. 55(8)
مصطلحات موضوعية: Male, medicine.medical_specialty, Cardiac Catheterization, medicine.medical_treatment, Hemodynamics, Blood Pressure, Coronary Disease, Coronary Angiography, Angioplasty, Internal medicine, Medicine, Humans, Cardiac catheterization, business.industry, Blood flow, Middle Aged, Symptomatic relief, Coronary Vessels, Diagnostic catheterization, Blood pressure, Coronary vessel, Cardiology, Cineangiography, Radiology, Cardiology and Cardiovascular Medicine, business, Angioplasty, Balloon
الوصف: A difficult problem in coronary arteriography is the assessment of the hemodynamic significance of stenoses that appear angiographically to be of only moderate severity (25 to 75% diameter narrowing). This is particularly important in patients who may be candidates for invasive therapy, such as percutaneous transluminal coronary angioplasty (PTCA) or coronary bypass surgery. To determine the significance of such lesions, we measured transstenotic coronary pressure gradients in 15 patients with angiographically moderate stenoses. For comparison, similar measurements were made in 17 patients with severe stenoses (more than 75% diameter narrowing) being considered for PTCA. The transstenotic pressure gradients were measured with a 2.0Fr polyvinyl chloride catheter cleared of microbubbles of air by flushing with carbon dioxide and degassed saline solution and attached to a low-volume displacement transducer for optimal frequency response. Mean transstenotic pressure gradients greater than 10 mm Hg at rest or more than 20 mm Hg under conditions of high coronary blood flow, as induced by Renografin 76, appeared to be associated with objective evidence of myocardial ischemia and symptomatic relief from PTCA. Smaller pressure gradients occurred in patients whose symptoms probably were not ischemic in nature. Transstenotic pressure gradient determination performed at the time of diagnostic catheterization may provide assistance in clinical decision-making in selected patients with angiographically moderate stenoses.
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المؤلفون: Richard Abben, James M. Kirshenbaum, Peter L. Friedman, David C. Levin, Dale Adler, Peter Ganz, Lawrence M. Boxt, Thomas Shook, J.Daniel Garnic
المصدر: The American journal of cardiology. 56(12)
مصطلحات موضوعية: medicine.medical_specialty, business.industry, medicine.medical_treatment, Coronary Disease, Balloon, Coronary Angiography, Surgery, Angioplasty, Internal medicine, medicine, Cardiology, Humans, Radiology, Cardiology and Cardiovascular Medicine, business, Angioplasty, Balloon
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المؤلفون: Kenneth M. Rosen, Pablo Denes, Richard Abben
المصدر: Circulation. 59(5)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Bundle-Branch Block, Myocardial Infarction, Infarction, Cardiomegaly, Anterior Descending Coronary Artery, Left ventricular hypertrophy, QRS complex, Electrocardiography, Heart Conduction System, Physiology (medical), Internal medicine, Medicine, Humans, cardiovascular diseases, Myocardial infarction, Child, Aged, business.industry, Left bundle branch block, Computers, Right bundle branch block, Middle Aged, medicine.disease, Cardiology, Left anterior hemiblock, Female, Cardiology and Cardiovascular Medicine, business
الوصف: SUMMARY Examination of ECGs in patients with intermittent left bundle branch block (LBBB) may provide insight into mechanisms cause of LBBB. In this study, we obtained ECG files of patients with intermittent LBBB by mail solicitation of cardiologists. The group suitable for analysis included 275 patients in whom both LBBB was documented at least one 12-lead ECG was available which demonstrated absence of LBBB (ALBBB) after the first LBBB ECG. ALBBB ECGs revealed normalQRS in 151 patients (55%), abnormal QRS in 124 (45%). These 124 had one or more of the following: left ventricular hypertrophy 53 patients (19% of total group), myocardial infarction (MI) — 53 patients (19% of total group) conduction disturbance (QRS > 0.10 sec/or axis of −30° to −90°) — 52 patients (19% of total group). Sixty-three MIs were localized in the 53 patients; 31 (49%) were anteroseptal, seven (11%) were anterior, 17 (27%) were inferior eight (13%) were lateral (p ≤ 0.10). The 52 patients with conduction defects had the following: left anterior hemiblock-- 32 patients (62% of conduction defects, 12% of total group), incomplete LBBB 19 patients (31% of conduction defects, 7% of total group), right bundle branch block one patient (2% of conduction defect, 0.1% of total group). More than 50% of the patients with intermittent LBBB did not have abnormal QRS, suggesting an underlying cause of LBBB. If underlying infarction is present, it is most commonly anteroseptal, implying disease of the left anterior descending coronary artery. The site of most intermittent LBBB appears predivisional (His or main left bundle), since preexisting leftsided unifascicular block is infrequent.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec31fb02c64a2a6eef40908aa4fba00b
https://pubmed.ncbi.nlm.nih.gov/154979