المؤلفون: Mohamad Jihad Mansour, Elie Chammas, Michael Winkler, Wael AlJaroudi

المصدر: BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-8 (2023)

مصطلحات موضوعية: Coronary artery disease, Coronary computed tomography angiography, Exercise stress testing, Hemodynamic gain index, Diseases of the circulatory (Cardiovascular) system, RC666-701

الوصف: Abstract Background Many hemodynamic parameters provide limited information regarding obstructive coronary artery disease (CAD) during exercise stress testing particularly when exercise is suboptimal. Hemodynamic gain index (HGI) is a recent sensitive indicator of ischemia and has been associated with increased mortality. This study evaluated the clinical impact of HGI in patients who underwent concomitant exercise stress testing and coronary computed tomography angiography (CCTA). Methods A total of 284 consecutive patients from the executive health program between 2010 and 2018 were identified. Resting and peak heart rate (HR) as well as systolic blood pressure (SBP) measurements were recorded. Framingham risk score (FRS), Duke treadmill score (DTS) and HGI $$(\frac{{{\text{HRpeak}} \times {\text{SBPpeak}} - {\text{HRrest}} \times {\text{SBPrest}}}}{{{\text{HRrest}} \times {\text{SBPrest}}}})$$ ( HRpeak × SBPpeak - HRrest × SBPrest HRrest × SBPrest ) were calculated. The latter was divided into quartiles. CCTA was used as a reference test to detect any CAD. Multivariate analysis and artificial neural network were used to determine the independent predictors of obstructive CAD. Results Mean age was 53 ± 12 years with 83% male. Mean HGI was 1.74 ± 0.67, with cut-off value of severely blunted HGI ≤ 1.25 (Quartile 4). Patients with severely blunted HGI were older, had higher FRS, and worse DTS. Patients with obstructive CAD had lower HGI when compared to those with normal CCTA/non-obstructive CAD (1.36 ± 0.53 vs. 1.77 ± 0.67, P = 0.005), and showed a higher prevalence of severely blunted HGI (44% vs. 22%, P = 0.019). After adjusting for traditional risk factors, HGI remained an independent predictor of obstructive CAD while severely blunted HGI was associated with threefold increased odds of having obstructive CAD (P = 0.05). Using artificial intelligence analysis, severely blunted HGI independently predicted obstructive CAD with an area under the curve of 0.83 and 0.96, and normalized importance of HGI of 100% and 63%, respectively for different models. Conclusions Among patients who underwent concomitant exercise stress testing and CCTA, severely blunted HGI independently predicted obstructive CAD after multivariate adjustment for traditional risk factors.

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1471-2261

URL الوصول: https://doaj.org/article/88c587ee81254ef5a862a3675eb6e1b9

المؤلفون: Himax Patel, Sean Harrell, Haitham Hreibe, Musa Sharkawi, Wael AlJaroudi

المصدر: Case Reports in Cardiology, Vol 2023 (2023)

مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701

الوصف: Leadless pacing systems have revolutionized the field of electrophysiology given its low complication rates and almost non-existent rate of infections compared with traditional pacemakers. These devices boast resistance to infections given its unique features; however, as described in this report, device-related infection from these leadless devices is still possible. In patients with leadless pacing system that is persistently bacteremic in the future, evaluation of the device with transesophageal echocardiogram or intracardiac echocardiography should be performed, and if vegetation is noted on the device, device extraction should highly be considered, along with empiric intravenous antibiotics. Lastly, new leadless device should not be re-implanted within 2 weeks of the removal of the infected device to prevent seeding of the new device.

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2090-6412

URL الوصول: https://doaj.org/article/c3a68ab54a4648d992937c1beb29a420

المؤلفون: Yasar Sattar, Talal Almas, Junaid Arshad, Mohamed Zghouzi, Waqas Ullah, Tanveer Mir, Mohamed O. Mohamed, Islam Y. Elgendy, Wael Aljaroudi, Anand Prasad, Richard Shlofmitz, Mamas A. Mamas, Dean J. Kereiakes, M. Chadi Alraies

المصدر: International Journal of Cardiology: Heart & Vasculature, Vol 39, Iss , Pp 100975- (2022)

مصطلحات موضوعية: IVL, Intravascular lithotripsy, Coronary artery calcification, Diseases of the circulatory (Cardiovascular) system, RC666-701

الوصف: Background: Intravascular lithotripsy (IVL) can be used to assist stent deployment in severe coronary artery calcifications (CAC). Methods: Studies employing IVL for CAC lesions were included. The primary outcomes included clinical and angiographic success. The secondary outcomes, including lumen gain, maximum calcium thickness, and calcium angle at the final angiography site, minimal lumen area site, and minimal stent area site, were analyzed by the random-effects model to calculate the pooled standardized mean difference. Tertiary outcomes included safety event ratios. Results: Seven studies (760 patients) were included. The primary outcomes: pooled clinical and angiographic success event ratio parentage of IVL was 94.4% and 94.8%, respectively. On a random effect model for standard inverse variance for secondary outcomes showed: minimal lumen diameter increase with IVL was 4.68 mm (p-value

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352906722000240; https://doaj.org/toc/2352-9067

URL الوصول: https://doaj.org/article/a6f1e278ac23483ea18076623982784f

المؤلفون: Mohamad Jihad Mansour, Malek Rahal, Elie Chammas, Omar Hamoui, Wael Aljaroudi

المصدر: Annals of Pediatric Cardiology, Vol 11, Iss 2, Pp 217-218 (2018)

مصطلحات موضوعية: Cardiac involvement, cardiac magnetic resonance, hypereosinophilic syndrome, Medicine, Pediatrics, RJ1-570, Diseases of the circulatory (Cardiovascular) system, RC666-701

الوصف: A 9-year-old boy with hypereosinophilic syndrome (HES) was referred for cardiac magnetic resonance (CMR) imaging following an abnormal echocardiogram that showed a large mass layered on the inferolateral wall of the left ventricle, causing secondary severe mitral regurgitation. Cardiac involvement in HES usually affects the ventricular apex. In our case, CMR confirmed the presence of a large mural thrombus of 0.9 cm × 4.2 cm. This unusual cardiac involvement in HES was diagnosed in its intermediate thrombotic stage. CMR is very sensitive and specific in staging the disease. It explained the etiology of mitral regurgitation and guided therapy, especially when echocardiography was nonconclusive.

وصف الملف: electronic resource

Relation: http://www.annalspc.com/article.asp?issn=0974-2069;year=2018;volume=11;issue=2;spage=217;epage=218;aulast=Mansour; https://doaj.org/toc/0974-2069

URL الوصول: https://doaj.org/article/72a690541c144da99f46f76491c08235

المؤلفون: Khalil, Jalkh, Kayla, Shahbazian, Phong, Nguyen, Wael, AlJaroudi, Evan, Hiner, Adnan, AlJaroudi, Haitham, Hreibe

المصدر: In Journal of Electrocardiology

المؤلفون: Khalil Jalkh, Wael AlJaroudi

المصدر: Journal of Nuclear Cardiology.

مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fa3b6e15301da5731d6e4c0f43b7b077
https://doi.org/10.1007/s12350-023-03232-4

المؤلفون: Sean Harrell, Adam E. Berman, Lavannya Atri, Michael C Morgan, Wael AlJaroudi

المصدر: World Journal of Radiology

مصطلحات موضوعية: education.field_of_study, medicine.medical_specialty, Myocarditis, medicine.diagnostic_test, Coronavirus disease 2019 (COVID-19), business.industry, Population, COVID-19, Minireviews, Gold standard (test), medicine.disease, Patient management, Coronavirus, Cardiac magnetic resonance imaging, Infected patient, Internal medicine, medicine, Cardiology, Late gadolinium enhancement, Cardiovascular complications, Cardiovascular magnetic resonance, business, education

الوصف: There is a growing evidence of cardiovascular complications in coronavirus disease 2019 (COVID-19) patients. As evidence accumulated of COVID-19 mediated inflammatory effects on the myocardium, substantial attention has been directed towards cardiovascular imaging modalities that facilitate this diagnosis. Cardiac magnetic resonance imaging (CMRI) is the gold standard for the detection of structural and functional myocardial alterations and its role in identifying patients with COVID-19 mediated cardiac injury is growing. Despite its utility in the diagnosis of myocardial injury in this population, CMRI's impact on patient management is still evolving. This review provides a framework for the use of CMRI in diagnosis and management of COVID-19 patients from the perspective of a cardiologist. We review the role of CMRI in the management of both the acutely and remotely COVID-19 infected patient. We discuss patient selection for this imaging modality; T1, T2, and late gadolinium enhancement imaging techniques; and previously described CMRI findings in other cardiomyopathies with potential implications in COVID-19 recovered patients.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5102c7f4810714462965d62a85c2cfb
http://europepmc.org/articles/PMC8473436

المؤلفون: Philip, Bucur, Corey, Smith, Wael, AlJaroudi, Adam E, Berman

المصدر: The American Journal of the Medical Sciences. 364:e79-e80

مصطلحات موضوعية: Myocarditis, COVID-19 Vaccines, SARS-CoV-2, Vaccination, Humans, COVID-19, General Medicine, Magnetic Resonance Imaging

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a6b23fa3ce900c5e359a1e7a8e836a
https://doi.org/10.1016/j.amjms.2022.06.024

المؤلفون: Wael AlJaroudi

المصدر: Journal of Nuclear Cardiology. 28:1775-1780

مصطلحات موضوعية: Clinical Practice, business.industry, Library science, Medicine, Radiology, Nuclear Medicine and imaging, Cardiology and Cardiovascular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d6946089676883ebb86bea4935f09a72
https://doi.org/10.1007/s12350-021-02664-0

المؤلفون: Amr Essa, Himax Patel, Mark Schwade, Walker Barmore, Austin West, Seena Mansouri, Wael Aljaroudi

المصدر: Journal of the American College of Cardiology. 81:1741

مصطلحات موضوعية: Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::92e87cfd1f65f15c8a551dca31fe0191
https://doi.org/10.1016/s0735-1097(23)02185-x