المؤلفون: Lein A; Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria., Brkic F; Department of Otorhinolaryngology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Liu DT; Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria., Haas M; Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria., Salkic A; Department of Otorhinolaryngology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Ibrisevic A; Department of Otorhinolaryngology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Uscuplic S; Department of Otorhinolaryngology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Harcinovic A; Department of Otorhinolaryngology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina., Thurner T; Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria., Brkic FF; Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.

المصدر: Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale [Acta Otorhinolaryngol Ital] 2024 Jun; Vol. 44 (3), pp. 169-175. Date of Electronic Publication: 2024 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pacini editore Country of Publication: Italy NLM ID: 8213019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1827-675X (Electronic) Linking ISSN: 0392100X NLM ISO Abbreviation: Acta Otorhinolaryngol Ital Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/epidemiology , Head and Neck Neoplasms*/therapy , Head and Neck Neoplasms*/epidemiology, Humans ; Male ; Female ; Aged ; Middle Aged ; Retrospective Studies ; Bosnia and Herzegovina/epidemiology ; Adult ; Aged, 80 and over ; Pandemics

مستخلص: Objective: Despite multiple studies from high-income countries, reports from low- and middle-income countries on the impact of COVID-19 on head and neck cancer care remain sparse. This study aimed to assess the effects of the COVID-19 pandemic on head and neck cancer patients at a tertiary reference centre in Bosnia and Herzegovina.
Methods: We included 228 patients with malignant head and neck tumours evaluated and treated between January 1, 2019, and December 31, 2021. Patient demographics, histological characteristics, and treatment modalities were retrospectively obtained and compared between the pre-pandemic period (pre-COVID-19 group) and the period after the implementation of COVID-19 restrictive measures (COVID-19 group).
Results: Patients were significantly older during the COVID-19 pandemic. In particular, 63 patients (44.7%) were under 65 and 78 (55.3%) were 65 or older, while in the pre-COVID-19 period, 53 patients (60.9%) were under 65 and 34 (39.1%) were 65 or older (p = 0.017). The pre-COVID-19 and COVID-19 groups did not significantly differ regarding other patient- and tumour characteristics, or primary treatment modalities.
Conclusions: During the COVID-19 pandemic, significantly fewer patients were under 65 at the time of initial work-up, potentially reflecting the more enhanced disease-related anxiety of the younger population. Future studies are warranted to address this population's specific educational and psychological needs to ensure appropriate cancer care.
(Copyright © 2024 Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Rome, Italy.)

المؤلفون: I SB; Clinical Center of the University of Sarajevo, Unit for Clinical Microbiology, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina; University of Sarajevo, Faculty of Health Studies, Stjepana Tomića 1, 71000 Sarajevo, Bosnia and Herzegovina. Electronic address: irma.sb@fzs.unsa.ba., E Z; Clinical Center of the University of Sarajevo, Unit for Clinical Microbiology, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina; University of Sarajevo, Faculty of Health Studies, Stjepana Tomića 1, 71000 Sarajevo, Bosnia and Herzegovina., A Č; Clinical Center of the University of Sarajevo, Unit for Clinical Microbiology, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina., A DL; Clinical Center of the University of Sarajevo, Unit for Clinical Microbiology, Bolnička 25, 71000 Sarajevo, Bosnia and Herzegovina; University of Sarajevo, Faculty of Health Studies, Stjepana Tomića 1, 71000 Sarajevo, Bosnia and Herzegovina; Sarajevo Medical School, University Sarajevo School of Science and Technology, Hrasnička cesta 3a, 71000 Sarajevo, Bosnia and Herzegovina.

المصدر: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2024 Jun; Vol. 109 (2), pp. 116268. Date of Electronic Publication: 2024 Mar 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8305899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0070 (Electronic) Linking ISSN: 07328893 NLM ISO Abbreviation: Diagn Microbiol Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Real-Time Polymerase Chain Reaction*/methods , DNA, Viral*/genetics , DNA, Viral*/isolation & purification, Humans ; Bosnia and Herzegovina ; Male ; Female ; Adult ; Mpox (monkeypox)/diagnosis ; Mpox (monkeypox)/virology ; Mpox (monkeypox)/epidemiology ; Middle Aged ; Adolescent ; Young Adult ; Tertiary Care Centers ; Child ; Monkeypox virus/genetics ; Monkeypox virus/isolation & purification ; Skin/virology ; Molecular Diagnostic Techniques/methods

مستخلص: Mpox virus (MPXV) infection is difficult to distinguish from other (non-)infectious diseases. The etiology of rash can be differentiated by real-time polymerase chain reaction (rtPCR) on different types of samples. The study aims to provide experience with emerging MPXV diagnostics in a tertiary-level laboratory in Bosnia and Herzegovina. From July-December 2022, a total of 18 mpox suspected persons were tested. MPXV infection was confirmed by rtPCR in 10/18 (55.56 %) persons. The number of cases reached a peak in October 2022. The lowest median Crossing point (Cp) (x̄ = 29.76) was obtained from a swab of skin lesions in a viral transport medium (VTM). Evaluating the Cp values for the 7/9 mpox cases from whom paired swab samples from different anatomic sites were collected, higher positivity of skin lesion swabs in VTM was observed. In conclusion, our data highlighted the confirmatory role of rtPCR in the diagnosis of MPXV in skin lesion samples.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024. Published by Elsevier Inc.)

المؤلفون: Primorac D, Anđelinović Š, Definis-Gojanović M, Škaro V; Vedrana Škaro, Greyledge Europe Ltd, Borongajska cesta 83H, 10000 Zagreb, Croatia, vedranaskaro@greyledgebiotech.com., Projić P, Čoklo M, Ašić A, Budowle B, Lee H, Holland MM, Baden M, Marjanović D

المصدر: Croatian medical journal [Croat Med J] 2024 Jun 13; Vol. 65 (3), pp. 239-248.

نوع المنشور: Journal Article; Review; Historical Article

بيانات الدورية: Publisher: Medicinska Naklada Country of Publication: Croatia NLM ID: 9424324 Publication Model: Print Cited Medium: Internet ISSN: 1332-8166 (Electronic) Linking ISSN: 03539504 NLM ISO Abbreviation: Croat Med J Subsets: MEDLINE

مواضيع طبية MeSH: Body Remains*, Bosnia and Herzegovina ; Humans ; Croatia ; Forensic Anthropology/methods ; Warfare ; DNA Fingerprinting

مستخلص: Over the past 30 years, forensic experts from Croatia and Bosnia and Herzegovina have embraced advanced technologies and innovations to enable great efficacy and proficiency in the identification of war victims. The wartime events in the countries of former Yugoslavia greatly influenced the application of the selected DNA analyses as routine tools for the identification of skeletal remains, especially those from mass graves. Initially, the work was challenging because of the magnitude of the events, technical aspects, and political aspects. Collaboration with reputable foreign forensic experts helped tremendously in the efforts to start applying DNA analysis routinely and with increasing success. In this article, we reviewed the most significant achievements related to the application of DNA analysis in identifying skeletal remains in situations where standard identification methods were insufficient.

المؤلفون: Meseldžić N, Prnjavorac B, Dujić T, Malenica M, Glamočlija U, Prnjavorac L, Bedak O, Imamović Kadrić S, Marjanović D, Bego T; Tamer Bego, Department of Pharmaceutical Biochemistry and Laboratory Diagnostics, Faculty of Pharmacy, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina, tamer.bego@ffsa.unsa.ba.

المصدر: Croatian medical journal [Croat Med J] 2024 Jun 13; Vol. 65 (3), pp. 220-231.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Medicinska Naklada Country of Publication: Croatia NLM ID: 9424324 Publication Model: Print Cited Medium: Internet ISSN: 1332-8166 (Electronic) Linking ISSN: 03539504 NLM ISO Abbreviation: Croat Med J Subsets: MEDLINE

مواضيع طبية MeSH: Serine Endopeptidases*/genetics , COVID-19*/genetics , COVID-19*/epidemiology , Angiotensin-Converting Enzyme 2*/genetics , Polymorphism, Single Nucleotide* , Severity of Illness Index* , Biomarkers*/blood, Humans ; Male ; Female ; Bosnia and Herzegovina ; Middle Aged ; SARS-CoV-2/genetics ; Adult ; Aged ; Genotype

مستخلص: Aim: To assess the association of single nucleotide polymorphisms (SNPs) in the ACE2 and TMPRSS2 genes with COVID-19 severity and key biomarkers.
Methods: The study involved 750 COVID-19 patients from Bosnia and Herzegovina, divided into three groups: mild, moderate, and severe cases. Genetic variations within the ACE2 (rs2285666) and TMPRSS2 (rs2070788) genes were examined with real-time polymerase chain reaction. Biochemical markers were determined with standard procedures.
Results: There was a significant difference in the rs2070788 genotype distribution between patients with mild and moderate symptoms, but not between other groups. For the rs2285666 polymorphism, no significant difference in genotype distribution was found. In patients with mild symptoms, carriers of the GG genotype of rs2070788 had significantly higher total bilirubin levels than carriers of the AA genotype. Similarly, carriers of the TT genotype of rs2285666 had significantly higher activated partial thromboplastin time and international normalized ratio, and lower lactate dehydrogenase levels compared with the CC genotype. Among patients with severe symptoms, carriers of the GG genotype showed significantly higher potassium levels than carriers of the AA genotype, while carriers of the TT genotype showed significantly higher erythrocyte count as well as hemoglobin and hematocrit levels compared with the CC genotype.
Conclusion: This study highlights the role of genetic factors, particularly SNPs in the ACE2 and TMPRSS2 genes, in determining COVID-19 severity, aiding patient risk assessment and prognosis.

المؤلفون: Gavic L; Study of Dental Medicine, School of Medicine, University of Split, Split, Croatia. lgavic@mefst.hr., Jerkovic A; Study of Dental Medicine, School of Medicine, University of Split, Split, Croatia., Ambarkova V; Department of Pediatric and Preventive Dentistry, Faculty of Dentistry, The Saints Cyril and Methodius University of Skopje, Skopje, North Macedonia., Jerkovic D; Study of Dental Medicine, School of Medicine, University of Split, Split, Croatia; Department of Maxillofacial and Oral Surgery, University Hospital of Split, Split, Croatia., Tadin A; Study of Dental Medicine, School of Medicine, University of Split, Split, Croatia; Department of Maxillofacial and Oral Surgery, University Hospital of Split, Split, Croatia.

المصدر: Acta odontologica Scandinavica [Acta Odontol Scand] 2024 Jun 11; Vol. 83, pp. 356-361. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Medical Journals Sweden AB Country of Publication: Sweden NLM ID: 0370344 Publication Model: Electronic Cited Medium: Internet ISSN: 1502-3850 (Electronic) Linking ISSN: 00016357 NLM ISO Abbreviation: Acta Odontol Scand Subsets: MEDLINE

مواضيع طبية MeSH: Empathy*, Humans ; Male ; Female ; Adult ; Surveys and Questionnaires ; Croatia ; Middle Aged ; Bosnia and Herzegovina ; Serbia

مستخلص: Objectives: Work-family conflict is a growing problem worldwide, because of changing work-family demographic trends and the spread of technology. Empathy, as the ability to understand and share the feelings of other people, is the essential component of emotional intelligence that plays a crucial role in healthcare settings. This study aimed to assess the level of emotional empathy and investigate its relationship with work-family role conflicts among dental medicine doctors.  Materials and methods: In this study participated 589 doctors of dental medicine from Croatia, Serbia, Bosnia and Herzegovina. The questionnaire included general and demographic data, the Emotional Empathy Scale questionnaire and the Work and Family Role Conflict Assessment Scale questionnaire.  Results: The research results indicate no significant association between empathy and conflict between work and family roles (R = 0.032, p = 0.435). Women have achieved significantly higher scores in Emotional Empathy Scale (p ≤ 0.001), while there was no difference in Work and Family Role Conflict Assessment Scale according to gender (p = 0.194). A difference in emotional empathy was observed depending on where the respondents were employed (p = 0.045) and depending on the specialisation of the dental medicine (p = 0.021).  Conclusion: Female doctors of dental medicine demonstrated higher emotional empathy while the work-family role conflict is experienced equally by both genders.

المؤلفون: Arenliu Qosaj F; Master Program in Health Care Management, AAB College, Prishtina, Kosovo., Bourdeaux M; Program in Global Public Policy, Harvard Medical School, Boston, MA, USA.

المصدر: European journal of public health [Eur J Public Health] 2024 Jun 07; Vol. 34 (3), pp. 460-466.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9204966 Publication Model: Print Cited Medium: Internet ISSN: 1464-360X (Electronic) Linking ISSN: 11011262 NLM ISO Abbreviation: Eur J Public Health Subsets: MEDLINE

مواضيع طبية MeSH: Health Policy*, Humans ; Balkan Peninsula/epidemiology ; Bosnia and Herzegovina/epidemiology ; European Union ; Serbia/epidemiology ; Montenegro/epidemiology ; Republic of North Macedonia/epidemiology ; Albania/epidemiology ; Kosovo/epidemiology

مستخلص: Background: Albania, Bosnia and Herzegovina, Kosovo, Montenegro, North Macedonia and Serbia have committed to becoming European Union (EU) member states. This, among others, implies that candidate/potential candidate states adopt legally authorized EU policies, including health. The study aims to identify the main country-specific health policy areas critical to the EU accession health policy dimension and present the change in associated selected health indicators from 2000 to 2019.
Methods: The study draws on published reports and analyses of official statistics over time and cross-country. Health care policy adherence to the European Commission's recommended country-specific health actions was classified into five health policy areas: financing, payment, organization, regulation and persuasion. Key health policy areas for Western Balkan countries (WBCs) were identified. Health progress or lack thereof in catching up to the EU15 population health, health expenditure and the number of health professionals are measured.
Results: The European Commission prioritized financing and regulation for all WBCs in the five policy areas. Nine of the 18 analyzed selected health indicators showed divergence, and the other nine converged towards the EU15 averages. WBCs continue to face diverse public health challenges in improving life expectancy at birth, death rates caused by circulatory system diseases, malignant neoplasms, traffic accidents, psychoactive substance use, tuberculosis incidence, tobacco smoking prevalence and public-sector health expenditure.
Conclusions: By 2019, there is limited evidence of WBCs catching up to the average EU15 health levels and health care policies. Closer attention towards EU health and health care policies would be favourable.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the European Public Health Association.)

المؤلفون: Gligorić D; Faculty of Economics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina., Preradović Kulovac D; Faculty of Economics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.; Doctoral School of Business Informatics, Corvinus University of Budapest, Budapest, Hungary., Micic L; Faculty of Economics, University of Banja Luka, Banja Luka, Bosnia and Herzegovina ljubisa.micic@ef.unibl.org., Vulovic V; Institute for Health Research and Policy, University of Illinois at Chicago, Chicago, Illinois, USA.

المصدر: Tobacco control [Tob Control] 2024 Jun 04; Vol. 33 (Suppl 2), pp. s95-s100. Date of Electronic Publication: 2024 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9209612 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3318 (Electronic) Linking ISSN: 09644563 NLM ISO Abbreviation: Tob Control Subsets: MEDLINE

مواضيع طبية MeSH: Cigarette Smoking*/economics , Cigarette Smoking*/epidemiology , Cost of Illness*, Humans ; Bosnia and Herzegovina/epidemiology ; Adult ; Male ; Female ; Prevalence ; Middle Aged ; Young Adult ; Adolescent ; Tobacco Products/economics ; Aged

مستخلص: Background: Cigarette use is one of the major risk factors for non-communicable diseases in Bosnia and Herzegovina, with 41.1% of adults being current smokers in 2019 and almost half of current smokers using more than 20 cigarettes per day.
Methods: This study applies the prevalence-based, cost-of-illness approach to estimate the annual economic cost of smoking in Bosnia and Herzegovina in 2019.
Results: The study estimates that cigarette use by adults in Bosnia and Herzegovina caused between 24.4% and 42.8% of all deaths in 2019 and a total economic cost of between €367.5 and €635.1 million (2.0%-3.5% of gross domestic product). The direct costs represent the largest share of the total cost (between 1.0% and 1.7% of gross domestic product).
Conclusion: Cigarette use imposes a significant health and economic burden in the society of Bosnia and Herzegovina. Various tobacco control measures can be implemented to prevent and reduce tobacco consumption and the negative health consequences of tobacco use. Numerous studies have shown taxes on tobacco products are very effective in reducing tobacco use, especially among certain demographic groups, such as youth and low-income individuals. Smoke-free laws have also shown benefits. Other policy measures that can be implemented include restrictions to advertising, limitations on who can purchase tobacco products, how and where they can be purchased, etc. In addition, governments could also implement various education programmes on the negative health consequences of smoking. The results of this study provide information that calls for prompt and strengthened implementation of tobacco control measures to reduce cigarette consumption in the country and improve the health outcomes and productivity of its inhabitants.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)

المؤلفون: Raguž F; Department of Nephrology, Division of Internal Medicine with Centre for Dialysis, University Hospital Mostar, Bijeli brijeg bb, Mostar, Bosnia and Herzegovina., Tomić M; Department of Nephrology, Division of Internal Medicine with Centre for Dialysis, University Hospital Mostar, Bijeli brijeg bb, Mostar, Bosnia and Herzegovina., Stojčić A; Department of Nephrology, Division of Internal Medicine with Centre for Dialysis, University Hospital Mostar, Bijeli brijeg bb, Mostar, Bosnia and Herzegovina., Tipurić M; Department of Urology, University Hospital Mostar, Bijeli brijeg bb, Mostar, Bosnia and Herzegovina., Volarić M; Department of Gastroenterology, Division of Internal Medicine with Centre for Dialysis, University Hospital Mostar, Bijeli brijeg bb, Mostar, Bosnia and Herzegovina., Bevanda S; Department of Endocrinology, Division of Internal Medicine with Centre for Dialysis, University Hospital Mostar, Bijeli brijeg bb, Mostar, Bosnia and Herzegovina.

المصدر: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy [Ther Apher Dial] 2024 Jun; Vol. 28 (3), pp. 409-416. Date of Electronic Publication: 2023 Dec 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Blackwell Pub Country of Publication: Australia NLM ID: 101181252 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-9987 (Electronic) Linking ISSN: 17449979 NLM ISO Abbreviation: Ther Apher Dial Subsets: MEDLINE

مواضيع طبية MeSH: Peritonitis*/etiology , Peritonitis*/epidemiology , Peritonitis*/microbiology , Peritoneal Dialysis, Continuous Ambulatory*/adverse effects , Peritoneal Dialysis, Continuous Ambulatory*/methods , Kidney Failure, Chronic*/therapy, Humans ; Male ; Female ; Middle Aged ; Bosnia and Herzegovina/epidemiology ; Aged ; Adult ; Retrospective Studies ; Aged, 80 and over

مستخلص: Introduction: Due to treatment of end-stage-renal-disease (ESRD), continuous peritoneal dialysis (CAPD) is used in 11% of cases and is associated with several PD-associated infections.
Methods: Clinical data on 71 patients with CAPD were evaluated in addition to exit site infections and episodes of acute peritonitis (AP).
Results: There were 39 men and 32 women. Average age was 61 years when we began CAPD and average time spent on CAPD program was 3.35 years. Illness that dominantly caused ESRD was diabetes (23 patients). Exit site infection was mostly caused by S epidermidis-MRSE and AP was most commonly caused by Staphylococcus sp. group. Most common cause of death was cardiovascular disease. At the end of this study, 9 patients were alive and still on CAPD, 10 were transplanted, 15 switched to HD and 36 died.
Conclusion: Optimal prevention measures and treatment of infectious complications in CAPD is necessary for better treatment possibilities.
(© 2023 International Society for Apheresis and Japanese Society for Apheresis.)

المؤلفون: Maksimović Z; Department of Pathobiology and Epidemiology, Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, Sarajevo 71000, Bosnia and Herzegovina., Babić S; Department of Pathobiology and Epidemiology, Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, Sarajevo 71000, Bosnia and Herzegovina. Electronic address: senka.babic@vfs.unsa.ba., Zahirović A; Department of Clinical Sciences, Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, Sarajevo 71000, Bosnia and Herzegovina., Rifatbegović M; Department of Pathobiology and Epidemiology, Veterinary Faculty, University of Sarajevo, Zmaja od Bosne 90, Sarajevo 71000, Bosnia and Herzegovina.

المصدر: Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2024 Jun; Vol. 109, pp. 102171. Date of Electronic Publication: 2024 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 7808924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1667 (Electronic) Linking ISSN: 01479571 NLM ISO Abbreviation: Comp Immunol Microbiol Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Leptospirosis*/epidemiology , Leptospirosis*/veterinary , Leptospirosis*/microbiology , Dog Diseases*/epidemiology , Dog Diseases*/microbiology , Leptospira*/immunology , Antibodies, Bacterial*/blood, Animals ; Dogs ; Seroepidemiologic Studies ; Bosnia and Herzegovina/epidemiology ; Risk Factors ; Male ; Female ; Seasons ; Serogroup ; Agglutination Tests/veterinary ; Zoonoses/epidemiology

مستخلص: Leptospirosis is a (re) emerging zoonosis that occurs worldwide. This study aimed to assess seroprevalence of leptospirosis and to identify the most common reactive serovars and risk factors for seropositivity in apparently healthy stray dogs of unknown vaccination status in the Sarajevo region of Bosnia and Herzegovina. Positive microscopic agglutination test titres (≥ 1:25) were detected in 3.87% (156/4028) of samples and most of the sera reacted against one serovar (85.9%). Dogs were most commonly reactive to Canicola (40.4%) and Hardjo (33.3%), followed by Pomona (15.4%) Tarassovi (14.7%), Icterohaemorrhagiae (8.3%), Grippotyphosa (5.8%), Bratislava (1.3%) and Saxkoebing (0.6%). Dogs older than one year had higher odds of seropositivity compared to younger dogs. The seropositivity was higher in spring and autumn than in summer. These results advocate for the need of a control strategy for this zoonosis in the country, which should include sero-surveillance, monitoring, and the inclusion of additional serovars in the testing.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)

المؤلفون: Musa S; Institute for Public Health of the Federation of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina; Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina. Electronic address: s.musa@zzjzfbih.ba., Merdrignac L; Epiconcept, Paris, France., Skocibusic S; Institute for Public Health of the Federation of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina., Nedic R; Institute for Public Health of the Federation of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina., Cilovic-Lagarija S; Institute for Public Health of the Federation of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina., Kissling E; Epiconcept, Paris, France.

المصدر: Vaccine [Vaccine] 2024 May 31; Vol. 42 (15), pp. 3467-3473. Date of Electronic Publication: 2024 Apr 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/prevention & control , COVID-19*/immunology , COVID-19*/epidemiology , COVID-19 Vaccines*/immunology , COVID-19 Vaccines*/administration & dosage , SARS-CoV-2*/immunology , Vaccine Efficacy*, Humans ; Aged ; Male ; Bosnia and Herzegovina ; Female ; Middle Aged ; Case-Control Studies ; Retrospective Studies ; Aged, 80 and over ; Vaccination ; Vaccines, Inactivated

مستخلص: COVID-19 vaccine uptake in the Federation of Bosnia and Herzegovina (FBiH) accelerated in the second half of 2021, with greater vaccine availability. In this study, we estimated the vaccine effectiveness (VE) of complete primary series BBIBP-CorV vaccine against COVID-19 in patients aged 60 years and older, during the Delta-dominant period, using a test-negative case-control design. Surveillance sites were 11 primary health care centers (PHC) collecting patient data from October 1, 2021, to January 4, 2022, retrospectively according to a common protocol. In total, we included 1711 participants in the analysis: 933 cases and 778 controls. Of the 933 cases, 508 (54.4 %) had mild and 425 (45.6 %) had moderate to severe disease presentation. We observed no effectiveness against mild COVID-19. Overall vaccine effectiveness was 65.0 % (95 %CI: 40.1-79.5) against moderate to severe COVID-19. In time since vaccination analysis, VE was 78.7 % (95 % CI: 54.8-89.9) in patients who received their last dose < 90 days before onset; 66.0 % (95 % CI: -0.5-88.5) in those 90-119 days before onset; 42.1 % (95 % CI: -88.6-82.3) in those 120-149 days before onset and 45.0 % (95 % CI: -94.0-84.4) in those ≥ 150 days before onset. In our study, two doses of BBIBP-CorV provided considerable protection against moderate to severe COVID-19 in older adults, highest within 3 months after second dose, during the Delta-dominant period. Point estimates declined thereafter, suggesting a need for additional doses.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)