يعرض 1 - 10 نتائج من 140,373 نتيجة بحث عن '"supplementation"', وقت الاستعلام: 1.35s تنقيح النتائج
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    مؤتمر

    المصدر: 2024 11th International Conference on Computing for Sustainable Global Development (INDIACom) Computing for Sustainable Global Development (INDIACom), 2024 11th International Conference on. :309-313 Feb, 2024

    Relation: 2024 11th International Conference on Computing for Sustainable Global Development (INDIACom)

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    المصدر: Clinical Nutrition. 43(1):176-186

    الوصف: Background: Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are important structural components of neural cellular membranes and possess anti-inflammatory properties. Very preterm infants are deprived of the enhanced placental supply of these fatty acids, but the benefit of postnatal supplementation on brain development is uncertain. The aim of this study was to test the hypothesis that early enteral supplementation with ARA and DHA in preterm infants improves white matter (WM) microstructure assessed by diffusion-weighted MRI at term equivalent age.Methods: In this double-blind, randomized controlled trial, infants born before 29 weeks gestational age were allocated to either 100 mg/kg ARA and 50 mg/kg DHA (ARA:DHA group) or medium chain triglycerides (control). Supplements were started on the second day of life and provided until 36 weeks postmenstrual age. The primary outcome was brain maturation assessed by diffusion tensor imaging (DTI) using Tract-Based Spatial Statistics (TBSS) analysis.Results: We included 120 infants (60 per group) in the trial; mean (range) gestational age was 26+3 (22+6 - 28+6) weeks and postmenstrual age at scan was 41+3 (39+1 - 47+0) weeks. Ninety-two infants underwent MRI imaging, and of these, 90 had successful T1/T2 weighted MR images and 74 had DTI data of acceptable quality. TBSS did not show significant differences in mean or axial diffusivity between the groups, but demonstrated significantly higher fractional anisotropy in several large WM tracts in the ARA:DHA group, including corpus callosum, the anterior and posterior limb of the internal capsula, inferior occipitofrontal fasciculus, uncinate fasciculus, and the inferior longitudinal fasciculus. Radial diffusivity was also significantly lower in several of the same WM tracts in the ARA:DHA group.Conclusion: This study suggests that supplementation with ARA and DHA at doses matching estimated fetal accretion rates improves WM maturation compared to control treatment, but further studies are needed to ascertain any functional benefit.Clinical trial registration: www.clinicaltrials.gov; ID:NCT03555019.

    وصف الملف: electronic

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    دورية أكاديمية

    المصدر: Ecology and Evolution. 14(2)

    الوصف: When reproductive success is determined by the relative availabilities of a series of essential, non-substitutable resources, the theory of balanced fitness limitations predicts that the cost of harvesting a particular resource shapes the likelihood that a shortfall of that resource will constrain realized fitness. Plant reproduction through female function offers a special opportunity to test this theory; essential resources in this context include, first, the pollen received from pollinators or abiotic vectors that is used to fertilize ovules, and, second, the resources needed to provision the developing seeds and fruit. For many plants realized reproductive success through female function can be readily quantified in the field, and one key potential constraint on fitness, pollen limitation, can be assessed experimentally by manually supplementing pollen receipt. We assembled a comparative dataset of pollen limitation using only studies that supplement pollen to all flowers produced over the plants reproductive lifespan. Pre- and post-pollination costs were estimated using the weight of flowers and fruits and estimates of fruit set. Consistent with expectations, we find self-incompatible plants make greater pre-pollination investments and experience greater pollen limitation. However, contrary to theoretical expectations, when variation due to self-compatibility is accounted for by including self-compatibility in the statistical model as a covariate, we find no support for the prediction that plants that invest more heavily in pre-pollination costs are subject to greater pollen limitation. Strong within-species, between-population variation in the expression of pollen limitation makes the quantification of mean pollen limitation difficult. We urge plant ecologists to conduct more studies of pollen limitation using whole-plant pollen supplementation to produce a richer comparative dataset that would support a more robust test of the balanced limitations hypothesis.

    وصف الملف: application/pdf

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    دورية أكاديمية
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    دورية أكاديمية

    المصدر: Journal of Endocrinological Investigation: Official Journal of Italian Society of Endocrinology (SIE). :1-8

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    دورية أكاديمية

    المؤلفون: Das, LizaAff1, Aff2, Sachdeva, Naresh, Holick, Michael F., Devnani, Mahesh, Dutta, PinakiAff1, IDs12020024038950_cor5, Marwaha, Raman KumarAff5, IDs12020024038950_cor6

    المصدر: Endocrine: International Journal of Basic and Clinical Endocrinology. :1-9

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    دورية أكاديمية

    المؤلفون: Kitaneh, RaziAff1, Aff2, Aff3, Jalilian-Khave, Laya, Ysrayl, Binah BahtAff1, Aff2, Aff3, Borelli, AnnaAff1, Aff2, Aff3, Funaro, Melissa C., Potenza, Marc N.Aff1, Aff2, Aff5, Aff6, Aff7, Aff8, Angarita, Gustavo A.Aff1, Aff2, Aff3, IDs40473024002787_cor7

    المصدر: Current Behavioral Neuroscience Reports. :1-18