المؤلفون: Llata E; From the Centers for Disease Control and Prevention, Division of STD Prevention (NCHHSTP), Atlanta, GA., Tromble E; From the Centers for Disease Control and Prevention, Division of STD Prevention (NCHHSTP), Atlanta, GA., Schumacher C; Johns Hopkins University School of Medicine and Baltimore City Health Department, Baltimore, MD., Huspeni D; Minnesota Department of Health, Minneapolis/St. Paul, MN., Asbel L; Philadelphia Department of Public Health, Philadelphia, PA., Pathela P; New York City Department of Health & Mental Hygiene, New York City, NY., Kohn R; San Francisco Department of Public Health, San Francisco, CA., Kerani RP; Public Health-Seattle and King County and Department of Medicine, University of Washington, Seattle, WA., Barbee L; From the Centers for Disease Control and Prevention, Division of STD Prevention (NCHHSTP), Atlanta, GA., Bachmann L; From the Centers for Disease Control and Prevention, Division of STD Prevention (NCHHSTP), Atlanta, GA.

المصدر: Sexually transmitted diseases [Sex Transm Dis] 2024 Jul 01; Vol. 51 (7), pp. 493-498. Date of Electronic Publication: 2024 Apr 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: J B Lippincott Country of Publication: United States NLM ID: 7705941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-4521 (Electronic) Linking ISSN: 01485717 NLM ISO Abbreviation: Sex Transm Dis Subsets: MEDLINE

مواضيع طبية MeSH: Urethritis*/drug therapy , Urethritis*/diagnosis , Urethritis*/microbiology , Urethritis*/epidemiology , Mycoplasma genitalium*/isolation & purification , Mycoplasma Infections*/drug therapy , Mycoplasma Infections*/diagnosis , Mycoplasma Infections*/epidemiology , Recurrence*, Humans ; Male ; Retrospective Studies ; Adult ; Gonorrhea/drug therapy ; Gonorrhea/diagnosis ; Gonorrhea/epidemiology ; Young Adult ; Chlamydia Infections/drug therapy ; Chlamydia Infections/diagnosis ; Chlamydia Infections/epidemiology ; Anti-Bacterial Agents/therapeutic use ; Middle Aged ; Sexually Transmitted Diseases/drug therapy ; Sexually Transmitted Diseases/diagnosis ; Sexually Transmitted Diseases/epidemiology ; Azithromycin/therapeutic use ; Azithromycin/administration & dosage ; Adolescent ; Doxycycline/therapeutic use

مستخلص: Background: Mycoplasma genitalium is a major contributor to persistent/recurrent urethritis cases. However, there are limited published studies on recent trends of persistent/recurrent urethritis.
Methods: A retrospective analysis was conducted of men presenting with symptomatic urethritis in 16 sexually transmitted disease (STD) clinics from 2015 to 2019. Poisson regression was used to assess trends in the annual proportions of urethritis episodes with follow-up (FU) characterized with persistent/recurrent urethritis symptoms. Results were also stratified by results of chlamydia (CT) and gonorrhea (NG) testing and treatment prescribed.
Results: There were 99,897 urethritis episodes, from 67,546 unique men. The proportion of episodes with persistent/recurrent symptomatic FU visits increased 50.8% over a 4-year period (annual percentage change [APC], 11.3%; 95% confidence interval [CI], 6.5-16.3). Similar trends were observed in nonchlamydial nongonococcal urethritis episodes (APC, 12.7%; 95% CI, 6.8-18.9) but increases among those positive for NG (APC, 12.1%; 95% CI, -2.3 to -28.5) or for CT (APC, 7.3%; 95% CI, -6.7 to 23.5) were not statistically significant. Among episodes who received azithromycin as first-line treatment, increases in the proportion of persistent/recurrent FU visits were observed (APC, 12.6%; 95% CI, 8.6-16.7). For episodes where first-line treatment was doxycycline, no significant increases were detected (APC, 4.3%; 95% CI, -0.3 to 9.2).
Conclusions: We found an increase in the proportion of urethritis episodes with persistent or recurrent symptoms over time. Given these observed trends in episodes negative for NG or CT, an etiology not detectable by routine diagnostics was a likely factor in increased persistence, suggesting patients with urethritis may benefit from diagnostic testing for M. genitalium during an initial symptomatic presentation.
Competing Interests: Conflict of Interest and Sources of Funding: None declared.
(Copyright © 2024 American Sexually Transmitted Diseases Association. All rights reserved.)

المؤلفون: Mula D; Faculty of Medicine, Hasan Pristina University, Pristina, Kosovo.; National Institute of Public Health of Kosovo, Pristina, Kosovo.; Medical Center Hospital, Pristina, Kosovo.; Alma Mater Europaea, Campus College 'Rezonanca', Prishtina, Kosovo., Dervishi R; Faculty of Medicine, Hasan Pristina University, Pristina, Kosovo.; Medical Center Hospital, Pristina, Kosovo.; University Clinical Center of Kosovo, Pristina, Kosovo., Hoxha R; Faculty of Medicine, Hasan Pristina University, Prishtina, Kosovo.; National Institute of Public Health of Kosovo, Pristina, Kosovo., Dervishi L; Medical Center Hospital, Pristina, Kosovo., Gashi MM; Faculty of Medicine, Hasan Pristina University, Pristina, Kosovo.; Medical Center Hospital, Pristina, Kosovo., Muçaj S; Faculty of Medicine, Hasan Pristina University, Pristina, Kosovo.; National Institute of Public Health of Kosovo, Pristina, Kosovo., Muçaj E; Alma Mater Europaea, Campus College 'Rezonanca', Pristina, Kosovo., Kuçi L; University Clinical Center of Kosovo, Pristina, Kosovo.

المصدر: Medical science monitor basic research [Med Sci Monit Basic Res] 2024 Jun 26; Vol. 30, pp. e943939. Date of Electronic Publication: 2024 Jun 26.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: International Scientific Information, Inc Country of Publication: United States NLM ID: 101597444 Publication Model: Electronic Cited Medium: Internet ISSN: 2325-4416 (Electronic) Linking ISSN: 23254394 NLM ISO Abbreviation: Med Sci Monit Basic Res Subsets: MEDLINE

مواضيع طبية MeSH: Probiotics*/therapeutic use , Anti-Bacterial Agents*/therapeutic use , Cystitis*/drug therapy , Prostatitis*/drug therapy , Prostatitis*/microbiology , Urethritis*/drug therapy , Urethritis*/microbiology , Vulvovaginitis*/drug therapy , Vulvovaginitis*/microbiology, Humans ; Adult ; Male ; Female ; Middle Aged ; Adolescent ; Young Adult ; Treatment Outcome ; Urinary Tract Infections/drug therapy

مستخلص: BACKGROUND Urogenital bacterial infections have a high incidence in humans. The most frequent cause of infections of the urogenital tract is gram-negative bacteria. Antibiotics are very effective in curing infectious diseases but they are accompanied by health complications. Probiotics are live microorganisms that are believed to confer a beneficial effect on human health when consumed in adequate amounts. This study aimed to compare outcomes from antibiotic treatment with and without the use of probiotics in 897 patients with lower urogenital tract infections, including cystitis, urethritis, prostatitis, and vulvovaginitis. MATERIAL AND METHODS A total of 897 patients aged 18 to 55 years were included in this research. Patients were divided into an intervention group including 460 patients (254 women, 206 men) and a comparison group including 437 patients (240 women, 197 men). The probiotics received by patients were capsules of ProBalans®. The diagnosis of cystitis, urethritis, prostatitis, vulvovaginitis, and sexually transmitted infection was done using several tests, and antibiotics were used for treatment. Qualitative data were analyzed using the chi-square or Fisher exact test. RESULTS We found a significant difference regarding patients' impressions of improvement after therapy between patients in the intervention group and the comparison group. CONCLUSIONS Use of probiotics together with antibiotics in the treatment of urogenital tract infection can help to reduce the adverse effects of antibiotics, increase the efficiency of antibiotic therapy, and reduce bacterial resistance to antibiotics. However, further research is needed to confirm these potential health benefits.

المؤلفون: Castaño MJ; Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain. Electronic address: castano_mjearo@gva.es., Alcaraz MJ; Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain., Albert E; Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain., Navarro D; Microbiology Service, Hospital Clínico Universitario, INCLIVA Research Institute, Valencia, Spain; Department of Microbiology, School of Medicine, University of Valencia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.

المصدر: Enfermedades infecciosas y microbiologia clinica (English ed.) [Enferm Infecc Microbiol Clin (Engl Ed)] 2024 Jun-Jul; Vol. 42 (6), pp. 333-334. Date of Electronic Publication: 2024 May 04.

نوع المنشور: Letter; Case Reports; Journal Article

بيانات الدورية: Publisher: Elsevier España Country of Publication: Spain NLM ID: 101777541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2529-993X (Electronic) Linking ISSN: 2529993X NLM ISO Abbreviation: Enferm Infecc Microbiol Clin (Engl Ed) Subsets: MEDLINE

مواضيع طبية MeSH: Urethritis*/microbiology , Urethritis*/diagnosis , Ureaplasma urealyticum*/genetics , Ureaplasma urealyticum*/isolation & purification , Ureaplasma Infections*/diagnosis , Ureaplasma Infections*/microbiology , Multiplex Polymerase Chain Reaction*, Humans ; Male ; Adult ; Real-Time Polymerase Chain Reaction

المؤلفون: Nokchan N; Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.; Department of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand., Wongsurawat T; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Division of Medical Bioinformatics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Jenjaroenpun P; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.; Division of Medical Bioinformatics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Nitayanon P; Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Saechan C; Faculty of Medical Technology, Prince of Songkla University, Songkhla, Thailand., Thirakittiwatthana W; Department of Medical Technology, Faculty of Science and Technology, Bansomdejchaopraya Rajabhat University, Bangkok, Thailand., Tribuddharat C; Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. chanwit.tri@mahidol.ac.th.

المصدر: Current microbiology [Curr Microbiol] 2024 Jun 14; Vol. 81 (8), pp. 221. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article; Case Reports

بيانات الدورية: Publisher: Springer International Country of Publication: United States NLM ID: 7808448 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0991 (Electronic) Linking ISSN: 03438651 NLM ISO Abbreviation: Curr Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Urethritis*/microbiology , Genome, Bacterial* , Gonorrhea*/microbiology , Anti-Bacterial Agents*/pharmacology, Humans ; Male ; Thailand ; Adolescent ; Whole Genome Sequencing ; Microbial Sensitivity Tests ; Neisseria gonorrhoeae/genetics ; Neisseria gonorrhoeae/isolation & purification ; Neisseria gonorrhoeae/classification ; Neisseria gonorrhoeae/drug effects ; DNA Transposable Elements/genetics ; Drug Resistance, Bacterial/genetics

مستخلص: Schaalia turicensis is facultative anaerobic Gram-positive bacillus that commonly inhabits the oropharynx, gastrointestinal, and genitourinary tract of healthy individuals. This organism has been co-isolated with Neisseria gonorrhoeae from 15-year-old Thai male patient with gonococcal urethritis in Bangkok, Thailand. In this study, we characterized the class 1 integron in S. turicensis isolate using whole-genome sequencing and bioinformatics analysis. Sequencing analysis confirmed the presence of an imperfect class 1 integron located on chromosome and a novel 24.5-kb-long composite transposon, named Tn7083. The transposon Tn7083 carried genes encoding chloramphenicol resistance (cmx), sulfonamide resistance (sul1), and aminoglycoside resistance [aph(6)-Id (strB), aph(3'')-Ib (strA), aph(3')-Ia].
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

المؤلفون: Chambers LC; From the Departments of Epidemiology., Tapia KA; Global Health, University of Washington., Srinivasan S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center., Proll S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center., Morgan JL; HIV/STI/HCV Program, Public Health-Seattle and King County., Hoffman NG; Departments of Laboratory Medicine and Pathology., Lowens MS; HIV/STI/HCV Program, Public Health-Seattle and King County., Glick SN, Khosropour CM; From the Departments of Epidemiology., Golden MR, Hughes JP; Biostatistics., Manhart LE, Fredricks DN

المصدر: Sexually transmitted diseases [Sex Transm Dis] 2024 Jun 01; Vol. 51 (6), pp. 407-414. Date of Electronic Publication: 2024 Feb 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: J B Lippincott Country of Publication: United States NLM ID: 7705941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-4521 (Electronic) Linking ISSN: 01485717 NLM ISO Abbreviation: Sex Transm Dis Subsets: MEDLINE

مواضيع طبية MeSH: Homosexuality, Male* , Microbiota* , Urethra*/microbiology , Sexual Behavior* , Urethritis*/microbiology, Humans ; Male ; Adult ; RNA, Ribosomal, 16S/genetics ; Young Adult ; Longitudinal Studies ; Middle Aged ; Sexual and Gender Minorities

مستخلص: Background: Sexual behavior may influence the composition of the male urethral microbiota, but this hypothesis has not been tested in longitudinal studies of men who have sex with men (MSM).
Methods: From December 2014 to July 2018, we enrolled MSM with nongonococcal urethritis (NGU) attending a sexual health clinic. Men attended 5 in-clinic visits at 3-week intervals, collected weekly urine specimens at home, and reported daily antibiotics and sexual activity on weekly diaries. We applied broad-range 16S rRNA gene sequencing to urine. We used generalized estimating equations to estimate the association between urethral sexual exposures in the prior 7 days (insertive oral sex [IOS] only, condomless insertive anal intercourse [CIAI] only, IOS with CIAI [IOS + CIAI], or none) and Shannon index, number of species (observed, oral indicator, and rectal indicator), and specific taxa, adjusting for recent antibiotics, age, race/ethnicity, HIV, and preexposure prophylaxis.
Results: Ninety-six of 108 MSM with NGU attended ≥1 follow-up visit. They contributed 1140 person-weeks of behavioral data and 1006 urine specimens. Compared with those with no urethral sexual exposures, those with IOS only had higher Shannon index ( P = 0.03 ) but similar number of species and presence of specific taxa considered, adjusting for confounders; the exception was an association with Haemophilus parainfluenzae . CIAI only was not associated with measured aspects of the urethral microbiota. IOS + CIAI was only associated with presence of H. parainfluenzae and Haemophilus .
Conclusions: Among MSM after NGU, IOS and CIAI did not seem to have a substantial influence on measured aspects of the composition of the urethral microbiota.
Competing Interests: Conflict of Interest of Sources of Funding: This work was supported by the National Institutes of Health (grant number U19 AI113173). L.C.C. was supported by the National Institutes of Health (grant number TL1 TR002318 trainee support). K.A.T. was supported by the University of Washington/Fred Hutch Center for AIDS Research, a program funded by the National Institutes of Health (grant number P30 AI027757). Study data were collected and managed using Research Electronic Data Capture (REDCap) tools hosted at the University of Washington Institute of Translational Health Sciences and supported by the National Institutes of Health (grant number UL1 TR002319). C.M.K. has received donations of test kits and reagents from Hologic, Inc. M.R.G. has conducted studies unrelated to this work supported by grants from Hologic, Inc. L.E.M. has received research support and honoraria from Hologic, Inc., and Nabriva Therapeutics. All other authors declare that they have no conflict of interest.
(Copyright © 2024 American Sexually Transmitted Diseases Association. All rights reserved.)

المؤلفون: Samra RS; Infectious Diseases, Alfred Health, Melbourne, Victoria, Australia ranjit.samra@doctors.org.uk.; Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia., Plummer EL; Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.; Central Clinical School, Monash University, Melbourne, Victoria, Australia., Vodstrcil L; Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.; Central Clinical School, Monash University, Melbourne, Victoria, Australia., Bradshaw CS; Melbourne Sexual Health Centre, Alfred Health, Melbourne, Victoria, Australia.; Central Clinical School, Monash University, Melbourne, Victoria, Australia.

المصدر: Sexually transmitted infections [Sex Transm Infect] 2024 Apr 18; Vol. 100 (3), pp. 189. Date of Electronic Publication: 2024 Apr 18.

نوع المنشور: Case Reports; Letter

بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9805554 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-3263 (Electronic) Linking ISSN: 13684973 NLM ISO Abbreviation: Sex Transm Infect Subsets: MEDLINE

مواضيع طبية MeSH: Haemophilus Infections*/diagnosis , Haemophilus Infections*/drug therapy , Urethritis*/diagnosis , Urethritis*/drug therapy, Humans ; Male ; Anti-Bacterial Agents/therapeutic use ; Haemophilus influenzae

مستخلص: Competing Interests: Competing interests: None declared.

المؤلفون: Obafemi OA; Public Health Institute at Denver Health, 601 Broadway, 8th Floor, MC 2800, Denver, CO 80203-3407, USA; Department of Family Medicine, University of Colorado Denver, Aurora, CO, USA., Rowan SE; Public Health Institute at Denver Health, 601 Broadway, 8th Floor, MC 2800, Denver, CO 80203-3407, USA; Division of Infectious Diseases, Department of Medicine, University of Colorado Denver, Aurora, CO, USA., Nishiyama M; Public Health Institute at Denver Health, 601 Broadway, 8th Floor, MC 2800, Denver, CO 80203-3407, USA., Wendel KA; Public Health Institute at Denver Health, 601 Broadway, 8th Floor, MC 2800, Denver, CO 80203-3407, USA; Division of Infectious Diseases, Department of Medicine, University of Colorado Denver, Aurora, CO, USA. Electronic address: karen.wendel@dhha.org.

المصدر: The Medical clinics of North America [Med Clin North Am] 2024 Mar; Vol. 108 (2), pp. 297-310. Date of Electronic Publication: 2023 Sep 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: W B Saunders Country of Publication: United States NLM ID: 2985236R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-9859 (Electronic) Linking ISSN: 00257125 NLM ISO Abbreviation: Med Clin North Am Subsets: MEDLINE

مواضيع طبية MeSH: Urethritis*/diagnosis , Urethritis*/drug therapy , Urethritis*/complications , Mycoplasma genitalium* , Uterine Cervicitis*/complications , Uterine Cervicitis*/drug therapy , Mycoplasma Infections*/diagnosis , Mycoplasma Infections*/drug therapy , Mycoplasma Infections*/complications , Pelvic Inflammatory Disease*/diagnosis , Pelvic Inflammatory Disease*/drug therapy , Pelvic Inflammatory Disease*/complications , Proctitis*/complications , Proctitis*/drug therapy, Pregnancy ; Female ; Humans ; Male ; Anti-Bacterial Agents/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Moxifloxacin/therapeutic use ; Macrolides/therapeutic use ; Drug Resistance, Bacterial ; Primary Health Care

مستخلص: Mycoplasma genitalium (MG) is an emerging sexually transmitted infection, which appears to be a cause of urethritis and cervicitis and has been associated with pelvic inflammatory disease (PID), epididymitis, proctitis, infertility, complications during pregnancy, and human immunodeficiency virus (HIV) transmission. Three Food and Drug Administration (FDA) approved tests are available. Testing should be focused to avoid inappropriate antibiotic use. The Center of Disease Control and Prevention (CDC) guidelines recommend testing for persistent male urethritis, cervicitis, and proctitis and state that testing should be considered in cases of PID. Testing is also recommended for sexual contacts of patients with MG. Testing is not recommended in asymptomatic patients, including pregnant patients, who do not have a history of MG exposure. Although resistance-guided therapy is recommended, there are currently no FDA approved tests for MG macrolide resistance, and tests are not widely available in the United States. The CDC recommends 2-step treatment with doxycycline followed by azithromycin or moxifloxacin. Moxifloxacin is recommended if resistance testing is unavailable or testing demonstrates macrolide resistance..
(Copyright © 2023 Elsevier Inc. All rights reserved.)

المؤلفون: Pérez-Bertólez S; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain. Electronic address: spbertolez@yahoo.es., Casal-Beloy I; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain., Martín-Solé O; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain., Carbonell M; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain., Capdevila B; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain., Tarrado X; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain., García-Aparicio L; Pediatric Urology Unit, Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain.

المصدر: Journal of pediatric urology [J Pediatr Urol] 2024 Feb; Vol. 20 (1), pp. 134-137. Date of Electronic Publication: 2023 Sep 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101233150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4898 (Electronic) Linking ISSN: 14775131 NLM ISO Abbreviation: J Pediatr Urol Subsets: MEDLINE

مواضيع طبية MeSH: Urethritis*/drug therapy , Urethritis*/diagnosis, Child ; Humans ; Urethra ; Behavior Therapy ; Recurrence ; Steroids

مستخلص: Idiopathic urethritis (IU) is difficult to manage and there is no standarized therapy. The technique of local steroid injection (LSI) for the treatment of IU in children and the results of the patients undergoing LSI from 2020 to 2021 in a single center are presented. Seven patients with IU underwent LSI. An internal urethrotomy was also performed in two patients with stricture. Complete resolution of symptoms and signs occurred in six patients. The remaining patient did not achieve total remission but did substantially improve symptoms. LSI seems to be an effective alternative for treatment of IU in children.
Competing Interests: Conflict of interest None.
(Copyright © 2023 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.)

المؤلفون: Vallejo-Ruiz MS; STI/Dermatology Department, Centro de Diagnóstico Médico, Madrid City Council, Madrid, Spain.; Dermatology Department, Hospital Universitario Infanta Cristina, Parla, Madrid, Spain., Sandoval-Garcés M; STI/Dermatology Department, Centro de Diagnóstico Médico, Madrid City Council, Madrid, Spain.; Department of Dermatology, School of Medicine. University of Chile, Santiago de Chile, Chile., Bru-Gorraiz FJ; STI/Dermatology Department, Centro de Diagnóstico Médico, Madrid City Council, Madrid, Spain., Martín-Gorgojo A; STI/Dermatology Department, Centro de Diagnóstico Médico, Madrid City Council, Madrid, Spain.

المصدر: International journal of STD & AIDS [Int J STD AIDS] 2024 Feb; Vol. 35 (2), pp. 155-157. Date of Electronic Publication: 2023 Oct 18.

نوع المنشور: Case Reports; Journal Article

بيانات الدورية: Publisher: Sage Country of Publication: England NLM ID: 9007917 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1052 (Electronic) Linking ISSN: 09564624 NLM ISO Abbreviation: Int J STD AIDS Subsets: MEDLINE

مواضيع طبية MeSH: Chlamydia Infections*/diagnosis , Urethritis*/diagnosis , Urethritis*/drug therapy , Urethritis*/etiology , Gonorrhea*/complications , Gonorrhea*/diagnosis , Gonorrhea*/drug therapy, Humans ; Chlamydia trachomatis ; Neisseria gonorrhoeae/genetics ; Doxycycline/therapeutic use

مستخلص: Tyson's glands are sebaceous glands located on each side of the frenulum that communicate with the preputial sac, and their inflammation can be an infrequent complication of urethritis. We describe a rare case that presented with urethral discharge and parafrenular swelling with mucopurulent discharge a week after an unprotected sexual encounter. The patient was empirically treated with 500 mg of ceftriaxone intramuscularly and 100 mg of doxycycline every 12 h for 14 days with symptomatic resolution. The urethral swab culture and the urine polymerase chain reaction (PCR) were negative for Neisseria gonorrhoeae and Chlamydia trachomatis , therefore, and given the response to treatment, nongonococcal tysonitis was diagnosed.
Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

المؤلفون: Sarier M; Istinye University, Department of Urology - İstanbul, Turkey.; Medical Park Hospital, Department of Urology - Antalya, Turkey., Kasap E; University of Health Science, Tepecik Education and Research Hospital, Department of Obstetrics and Gynecology - İzmir, Turkey.

المصدر: Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2024 Apr 22; Vol. 70 (3), pp. e20231532. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).

نوع المنشور: Editorial; Letter

بيانات الدورية: Publisher: Associação Médica Brasileira Country of Publication: Brazil NLM ID: 9308586 Publication Model: eCollection Cited Medium: Internet ISSN: 1806-9282 (Electronic) Linking ISSN: 01044230 NLM ISO Abbreviation: Rev Assoc Med Bras (1992) Subsets: MEDLINE

مواضيع طبية MeSH: Urethritis*/diagnosis , Urethritis*/microbiology, Humans ; Acute Disease ; Gentian Violet ; Phenazines ; Male