المؤلفون: Manoj Kumar Dash, Remya Jayakumar, Namrata Joshi

المصدر: Journal of Complementary and Integrative Medicine. 19:71-82

مصطلحات موضوعية: 0303 health sciences, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, Transmission (medicine), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19, Disease, Medicine, Ayurvedic, Scientific evidence, 03 medical and health sciences, 0302 clinical medicine, Geography, Complementary and alternative medicine, Environmental health, Pandemic, Thunderstorm, Animals, Humans, 030212 general & internal medicine, Integrative medicine, Pandemics, 030304 developmental biology

الوصف: Human-to-human transmission of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs most often when people are in the incubation stage of the disease or are carriers and have no symptoms. SARS-CoV-2 transmission on different levels showed that the cold and dry climate, hot wind and relative humid wind, maximum wind speed, turbulent wind, intensified recirculating flow were causing transmission higher than factors. The role of environmental factors described in Ayurveda like air, water, soil, season, frequent earthquakes, sunlight exposure, frequent thunderstorm with lightening, and factors from arthropods were revalidated in perspective of COVID-19 transmission. The authors searched the information regarding epidemic diseases in Ayurveda textbooks. Pubmed, Science Direct, Wikipedia, Elsevier, Lancet, and Springer were approached for the latest knowledge relating to SARS-CoV-2 and COVID-19. Google Scholar search engine was thoroughly checked upon for scientific evidence regarding the Ayurveda drugs. Various environmental factors like soil, air, water, frequent earthquake disasters, wildlife animals, aquatic birds, space, inevitable disastrous factors, weather or seasonal hazards, violent thunderstorm with lightning, intermediate hosts, sunlight exposure etc. were considered for their role in the genesis of the disease. The Ayurvedic concepts behind the etiology and development of epidemics are the same as modern epidemiological theories. The mysteries of many aspects of the current pandemic might be deciphered by traditional medicine knowledge and thus adding upon to the integrative medicine concept.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f016f5b4becaaf5b27aefc18c4c9ae
https://doi.org/10.1515/jcim-2020-0390

المؤلفون: Maheshkumar Kuppusamy, Sadhana Socrates, Poonguzhali Shanmugam, Sankaralingam Thirupathy Venkateswaran, Venugopal Vijayakumar

المصدر: Journal of Complementary and Integrative Medicine. 20:284-288

مصطلحات موضوعية: medicine.medical_specialty, Cross-sectional study, business.industry, Naturopathy, media_common.quotation_subject, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Resource (project management), Complementary and alternative medicine, Family medicine, Perception, Health care, medicine, Siddha, Population study, 030212 general & internal medicine, Integrative medicine, business, media_common

الوصف: Objectives Complementary and Alternate medicine (CAM) remains as the major source of healthcare for majority of the Indian population. This widespread resource needs to be strengthened, adequately trained and effectively utilized in the national health care delivery system for delivering an integrated and effective health care system. Methods A cross sectional study was conducted involving 200 adults in two different settings-a community setting (n=100), and a hospital setting (n=100). A semi-structured questionnaire was used. Results Both in the community and in the hospital, siddha (80%) was the most well-known system of medicine, followed by Yoga (72%) and Naturopathy in the study population. However, the knowledge about the various available CAM therapies still seemed to be limited. Conclusions Opinion on the integrated approach along with conventional medicine was welcoming. Still more awareness about these systems is required to facilitate integrative medicine in healthcare settings.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59d89f6082714141a1c9ed74a2fb711
https://doi.org/10.1515/jcim-2020-0194

المؤلفون: Stephen P. Meyer

المصدر: Journal of Complementary and Integrative Medicine. 14

مصطلحات موضوعية: Attitude of Health Personnel, Interprofessional Relations, Naturopathy, media_common.quotation_subject, MEDLINE, 03 medical and health sciences, 0302 clinical medicine, Physicians, Surveys and Questionnaires, Perception, Health care, Regional science, Humans, 030212 general & internal medicine, Cities, Spatial analysis, media_common, Ontario, Integrative Medicine, Spatial Analysis, business.industry, Professional Practice Location, Metropolitan area, Geography, Complementary and alternative medicine, 030220 oncology & carcinogenesis, Integrative medicine, business, Delivery of Health Care, Ontario canada

الوصف: Evaluating conventional medicine (CM) and complementary and alternative medicine (CAM) with respect to integration opportunities (such as patient referrals and professional knowledge sharing) and possible geographic implications is novel. This research utilizes nearest neighbour and local spatial autocorrelation statistical analyses and surveys directed towards Doctors of Naturopathic Medicine (NDs) and their patients to better understand the geographic patterns of NDs and potential integration qualities. While the statistical tests reveal that the offices of NDs and Doctors of Medicine (MDs) display clustered patterns in intermediately-sized census metropolitan areas in Ontario and that the majority of NDs are near MDs, proximity is not manifesting in discernible integration tendencies between NDs and MDs. The NDs polled were strongly in favour of greater integration with the CM sector (as were their patients) to: achieve better patient health outcomes and to gain efficiencies within the health care system. Yet, both surveys also indicate that the barriers to integration are substantial and, generally speaking, centre on the perception that many MDs lack respect for, and/or knowledge about, naturopathic approaches. It is speculated that as students in conventional medical schools are increasingly exposed to CAM approaches, perhaps more MDs in the future will be receptive to greater integration with CAM. Should this occur, then it is also possible that geographic proximity may be a catalyst for deeper CAM-CM integration; as it has been for CAM–CAM relationships.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06059a9bf6c6fc48ec02ab309cd5cde5
https://doi.org/10.1515/jcim-2015-0092

المؤلفون: Bento João Abreu, Matheus Anselmo Medeiros, Licyanne Ingrid Carvalho de Lemos, Naisandra Bezerra da Silva Farias, Tatiane Oliveira Teixeira, Lucia Fatima Campos Pedrosa, Flávio Santos da Silva, Karina Carla de Paula Medeiros, Camila Alexandrina Figueiredo, João Paulo Matos Santos Lima

المصدر: Journal of Complementary and Integrative Medicine. 18:719-725

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Very low-density lipoprotein, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, medicine.disease_cause, Antioxidants, Streptozocin, Diabetes Mellitus, Experimental, Immunomodulation, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Animals, Cysteine, Rats, Wistar, biology, Glycogen, Chemistry, Pancreatic islets, Streptozotocin, Rats, Oxidative Stress, Endocrinology, medicine.anatomical_structure, Complementary and alternative medicine, Catalase, Sulfoxides, biology.protein, Oxidative stress, medicine.drug, Lipoprotein

الوصف: Objectives S-methyl cysteine sulfoxide (SMCS) is a hydrophilic cysteine-containing natural compound found in plants and is known to possess antidiabetic and antioxidant properties. We investigated the antioxidant and immunomodulatory properties of SMCS, as well as histopathological changes in the liver and pancreas in streptozotocin (STZ)-induced diabetic rats. Methods The rats were divided into the following groups: control (CG), comprising non-diabetic rats; STZ-DB, comprising STZ-induced diabetic rats; and STZ-SMCS, comprising STZ-induced diabetic rats treated with SMCS. SMCS (200 mg/kg) was administered by gavage daily for 30 days. Biochemical and cytokine analyses, catalase (CAT) and superoxide dismutase (SOD) activities assays and histopathological analysis of liver and pancreas tissues were performed. Results SMCS treatment reduced glycemia (p Conclusions Oral treatment of SMCS showed improvement of the morphological alterations in liver and pancreatic islet in diabetic rats. These beneficial morphological effects of SMCS can be partially explained by IL-10 modulation associated with antioxidant action.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b637bd7269ef52e798e481d2a3183c
https://doi.org/10.1515/jcim-2020-0220

المؤلفون: T.M. Salman, Eli B Patrick, Adeyemi Fatai Odetayo, Michael O Allen, A R A Alada, Shakiru Ademola Salami

المصدر: Journal of Complementary and Integrative Medicine. 19:287-296

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Glucose uptake, medicine.medical_treatment, 030209 endocrinology & metabolism, Fructose, Propranolol, Jejunum, 03 medical and health sciences, chemistry.chemical_compound, Adrenergic Agents, Dogs, 0302 clinical medicine, Internal medicine, medicine, Animals, Insulin, Lactic Acid, Vein, Saline, Glycogen, Galactose, Intestines, Glucose, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Complementary and alternative medicine, chemistry, medicine.drug

الوصف: Objectives To investigate effect of beta adrenergic blockade on intestinal lactate production and glycogen concentration in dogs infused with hexoses. Methods Experiments were carried out on 35 fasted male anaesthetized dogs weighing between 9 and 16 kg. The animals were divided into 7 (5 dogs per group) groups. Group I dogs served as control and infused with normal saline, groups II-IV were intravenously infused with glucose (1.1 mg/kg/min), fructose (1.1 mg/kg/min) and galactose (1.1 mg/kg/min) respectively while groups V-VII animals were pretreated with propranolol (0.5 mg/kg) and were infused with glucose, fructose or galactose respectively. A vein draining the proximal segment of the jejunum was cannulated along with right and left femoral arteries and veins. Glucose uptake was calculated as the product of jejunal blood flow and the difference between arterial and venous glucose levels (A-V glucose), part of the jejunum tissue was homogenized for estimation of glycogen concentration, and plasma lactate was assayed using lactate colorimetric kit. Results The result showed significant increase in venous lactate production in response to glucose (78.30 ± 4.57 mg/dL), fructose (60.72 ± 1.82 mg/dL) and galactose (71.70 ± 1.30 mg/dL) when compared with the control group (51.75 ± 1.32 mg/dL) at (p0.05) in animals infused with hexoses only compared with propanolol pretreated group. Conclusions Results suggests that one of the possible fates of the enormous amount of glucose taken up by the intestine is conversion to lactate and not glycogen and β-adrenergic receptor does not affect it.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1891f5b7719833fed79475e3db0c61
https://doi.org/10.1515/jcim-2021-0062

المؤلفون: Farida Adly, Asmae Belbachir, Abdelhakim El Makssoudi, Abdelaziz El Amrani, Mariam Achir, Mohamed Dakir, Naima Bettach, Mohamed Blaghen, Jamal JamalEddine

المصدر: Journal of Complementary and Integrative Medicine. 19:467-470

مصطلحات موضوعية: Chromatography, Juniperus phoenicea, biology, Chemistry, Bacillus cereus, Biological activity, biology.organism_classification, Antimicrobial, 01 natural sciences, 030205 complementary & alternative medicine, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Column chromatography, Complementary and alternative medicine, Diterpene, Candida albicans, Antibacterial activity

الوصف: Objectives A mixture of Z and E communic acid is isolated for the first time from the cones of Juniperus phoenicea. Its biological activity was studied. Methods The plant material was extracted in a Soxhlet apparatus with n-hexane, the resulting extract was subjected to column chromatography (CC) on silica gel. The structure elucidation of the constituents of the isolated fraction was identified by comparison of its spectroscopic properties 1H and 13C NMR data with those reported in the literature. The antimicrobial assay of hexanic extract and isolated compounds was carried out by the disc diffusion and micro-dilution methods. Results A mixture of two diterpene acids isomers was isolated, with a high yield (68%). Their chemical structures were confirmed after comparing their spectral data with published reports. These natural products exhibited a significant antibacterial and antifungal activity against the tested strains. Indeed, for Bacillus cereus, Staphylococcus aureus, and Pseudomonas aeruginosa, the inhibition zone diameters (36–37 mm) was better than penicillin, novobiocin, and amoxicillin. For Candida albicans activity, it show that the mixture possess an activity similar to that of Metrazol. Against Escherichia coli, the inhibitory activity was found less than Amoxicillin. This is the first report of isolation of communic acid from J. phoenicea. Conclusions These results showed that the cones of J. phoenicea were an important source of communic acid, and its hexanic extract had the greatest potential antibacterial activity against both Gram-negative and Gram-positive bacteria and C. albicans.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5125cad949f0c8f64f06402884aec8bc
https://doi.org/10.1515/jcim-2019-0319

المؤلفون: Azizeh Farshbaf-Khalili, Parina Asgharian, Behnaz Sadeghzadeh Oskouei, Samad Hazhir, Sima Sanagoo

المصدر: Journal of Complementary and Integrative Medicine. 18:791-796

مصطلحات موضوعية: medicine.medical_specialty, 030219 obstetrics & reproductive medicine, Side effect, business.industry, Vitamin E, medicine.medical_treatment, Capsule, Semen, Gastroenterology, Sperm, food.food, law.invention, 03 medical and health sciences, Ceratonia siliqua, 0302 clinical medicine, food, Complementary and alternative medicine, Randomized controlled trial, law, Internal medicine, medicine, business, 030217 neurology & neurosurgery, Sperm motility

الوصف: Objectives To compare the effect of oral Ceratonia siliqua (Carob) and vitamin E on sperm parameters in idiopathic infertile men. Methods In this triple-blind randomized controlled trial study, fifty 20–45-year-old infertile men with idiopathic abnormal sperm parameters were selected among men referring to the infertility clinic of Al Zahra-Iran Hospital, and randomly allocated into two groups. The first group received Carob capsules, 500 mg, and the second group received vitamin E capsules three times a day for 90 days. The primary outcomes of this study were the sperm parameters (count, motility, and morphology). Results After the intervention, the mean of sperm count increased from 49.08 to 60.22 million/mL in the carob vs. it increased from 47.64 to 58.88 million/mL in the vitamin E group (adjusted mean difference (aMD)=1.124 million/ml, 95% CI: −12.892 to 15.141). The mean sperm motility increased from 45.90 to 52.90% in the carob group but decreased from 55.23 to 38.10% in the vitamin E group (aMD=17.22%, 95% CI: 8.53 to 25.92). The mean sperms with normal morphology increased from 11.52 to 67.05% in the carob, and from 10.20 to 77.47% in the vitamin E group (aMD=−10.88%, 95% CI: −22.30 to 0.536). There was no serious side effect during the treatment course. Conclusions Taking 1,500 mg oral dose of Carob capsule per day for 90 days improved sperm motility but had no significant effect for improving morphology and count comparing to vitamin E capsule.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f20eb15213a38cd62e74039590ae4e9f
https://doi.org/10.1515/jcim-2020-0095

المؤلفون: Ali A. Ismail, Hatem Fawzy Abd Elfatah Abo Saif, Alaa Mohamed El-Moatasem Mohamed

المصدر: Journal of Complementary and Integrative Medicine. 19:1013-1018

مصطلحات موضوعية: Intraocular pressure, Open angle glaucoma, Respiratory rate, business.industry, Type 2 Diabetes Mellitus, Glaucoma, 030209 endocrinology & metabolism, medicine.disease, law.invention, 03 medical and health sciences, 0302 clinical medicine, Blood pressure, Complementary and alternative medicine, Randomized controlled trial, law, Anesthesia, 030221 ophthalmology & optometry, Medicine, business, Body mass index

الوصف: Objectives Yoga is used as a complementary therapy to control the symptomatic and complicated consequences of type 2 diabetes mellitus (T2DM) but the effect of Jyoti-Trataka yoga (gazing steadily at a 4-feet away-fixed candle flame) on the intraocular pressure (IOP), autonomic control, and fasting blood glucose (FBG) in T2DM patients with high-tension primary open-angle glaucoma (POAG) was not previously investigated. This study aimed to search the effect of Jyoti-Trataka on IOP, systolic blood pressure (SBP), respiratory rate (RR), diastolic blood pressure (DBP), FBG, and pulse rate (PR) in T2DM patients with bilateral high-tension POAG. Methods The patients with a 52- to 67-year range and body mass index below 30 kg/m2 were randomly assigned to one of two 30-patient groups, study or control groups. Besides the administered oral hypoglycemic drugs by both groups, the study group only received one month of daily 55-min Jyoti-Trataka session. Results A significant decrease (p0.05). In-favor-of the study group, the between-group post-treatment comparison showed a significant improvement of all measures (p Conclusions Jyoti-Trataka is a good yogic complementary therapy that can be used to regulate autonomic functions, blood glucose, and IOP in T2DM patients with high-tension POAG.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a995999e5b89b7e43a85c4ee8702335
https://doi.org/10.1515/jcim-2021-0041

المؤلفون: Amrita Parida, Sudhishma, Vandana Blossom, Sahana D Acharya, Sheetal D Ullal, Nadira Noushida

المصدر: Journal of Complementary and Integrative Medicine. 19:897-903

مصطلحات موضوعية: 0301 basic medicine, biology, Offspring, business.industry, Physiology, Morris water navigation task, biology.organism_classification, Bacopa, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Complementary and alternative medicine, Gum acacia, Hippocampus (mythology), Medicine, Bacopa monnieri, Levetiracetam, Cognitive decline, business, 030217 neurology & neurosurgery, medicine.drug

الوصف: Objectives Levetiracetam (LEV) is an antiepileptic recommended during pregnancy. Bacopa monneri is a medicinal herb used in Ayurveda for improvement of cognition. Data on effects of LEV and Bacopa on cognition is inadequate. The study evaluated the cognitive effects of LEV on rat offspring of dams exposed to LEV and whether pretreatment with Bacopa monnieri, inhibits the potential cognitive decline by LEV. Methods Pregnant rats were allocated into four groups of three rats each. Groups 1, 2, 3 and 4 received 2% gum acacia, LEV 270 mg/kg, LEV 270 mg/kg + Bacopa 100 mg/kg and LEV 270 mg/kg + Bacopa 200 mg/kg respectively during pregnancy and lactation. Three pups from all dams were chosen at random and exposed to passive avoidance, Hebb-Williams and Morris water maze tests to check for their cognition and relevant histopathology was done. Results In the passive avoidance model groups 3 and 4, showed an increase in escape latency compared with group 2, demonstrating an improved learning (p=0.05). In Hebb-Williams maze, the time taken to reach reward chamber by group 2 increased compared to group 1, p=0.006, showing cognitive decline. Neuronal count in hippocampus and prefrontal cortex decreased significantly in group 2, which improved in group 3 & 4 however there was distortion of architecture in group 4. Conclusions LEV exposure in intrauterine and neonatal period induced cognitive decline in rat offsprings and Bacopa 100 mg/kg prevented LEV induced cognitive decline. However safety of exposure to Bacopa during the gestation period has to be evaluated.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::548b042ee3d8870f84136f9d58111d92
https://doi.org/10.1515/jcim-2020-0424

المؤلفون: Abdul Nasir Ansari, Mohammad Zaki Ahmad, Mohd Nayab

المصدر: Journal of Complementary and Integrative Medicine. 19:1019-1024

مصطلحات موضوعية: medicine.medical_specialty, Waist, business.industry, Statistical difference, Repeated measures design, 030204 cardiovascular system & hematology, medicine.disease, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Blood pressure, Complementary and alternative medicine, Quality of life, Internal medicine, medicine, 030212 general & internal medicine, Analysis of variance, Metabolic syndrome, business

الوصف: Objectives This study intended to evaluate the efficacy of Ḥammām-i-yabis (dry bath) in metabolic syndrome as primary objective and perceived improvement and changes in quality of life as secondary objective. Methods The study was designed as single arm, open-labelled, pre and post without control clinical trial comprising 30 diagnosed cases of metabolic syndrome belonging to 20–50 years of age of either sex. The enrolled patients were exposed to the dry heat of Ḥammām-i-yābis for 15 min at a temperature of 60 degree centigrade on every third day for a duration of 30 days (a total of 10 sittings). Objective parameters comprising systolic and diastolic blood pressure and waist circumference were assessed on every follow up, while other objective parameters (FBS, HDL and Serum Triglycerides) were assessed before and after the study. Results Significant statistical difference was observed in objective parameters. Two tailed paired Student’s t-test, (for pre and post) and repeated measure ANOVA (for 0, 15th and 30th day) were used to find the significance of mean change in study parameters. No significant adverse change appeared in safety parameters. Conclusions Ḥammām-i-yābis was found effective, safer, more feasible and less expensive regimenal modality for the patients of metabolic syndrome.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8386bf01562e022fde236e2b8fafbd6
https://doi.org/10.1515/jcim-2021-0072