المؤلفون: Rivera-Reyes A; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Ye S; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., E Marino G; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Egolf S; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., E Ciotti G; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Chor S; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Liu Y; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Posimo JM; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Park PMC; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA., Pak K; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Babichev Y; Department of Surgery and Institute of Medical Science, University of Toronto, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada., Sostre-Colón J; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Tameire F; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Leli NM; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Koumenis C; Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., C Brady D; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Mancuso A; Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Weber K; Department of Orthopedic Surgery, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Gladdy R; Department of Surgery and Institute of Medical Science, University of Toronto, Toronto, ON, Canada.; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada., Qi J; Department of Medicine, Harvard Medical School, Boston, MA, 02115, USA., Eisinger-Mathason TSK; Abramson Family Cancer Research Institute, Department of Pathology & Laboratory Medicine, Penn Sarcoma Program, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. karineis@pennmedicine.upenn.edu.

المصدر: Cell death & disease [Cell Death Dis] 2018 Oct 31; Vol. 9 (11), pp. 1108. Date of Electronic Publication: 2018 Oct 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Adaptor Proteins, Signal Transducing/*genetics , Autophagy/*genetics , Cell Cycle Proteins/*genetics , Muscle Neoplasms/*genetics , NF-kappa B/*genetics , Sarcoma/*genetics, Activating Transcription Factor 6/genetics ; Activating Transcription Factor 6/metabolism ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Autophagy/drug effects ; Azepines/pharmacology ; CLOCK Proteins/genetics ; CLOCK Proteins/metabolism ; Cell Cycle Proteins/metabolism ; Cell Differentiation ; Cell Line ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Neoplastic/pathology ; Circadian Clocks/drug effects ; Circadian Clocks/genetics ; Humans ; Mice ; Mice, Transgenic ; Muscle Neoplasms/drug therapy ; Muscle Neoplasms/metabolism ; Muscle Neoplasms/pathology ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Myoblasts/drug effects ; Myoblasts/metabolism ; Myoblasts/pathology ; NF-kappa B/metabolism ; Sarcoma/drug therapy ; Sarcoma/metabolism ; Sarcoma/pathology ; Signal Transduction ; Stem Cells/drug effects ; Stem Cells/metabolism ; Stem Cells/pathology ; Triazoles/pharmacology ; Unfolded Protein Response/drug effects ; Vorinostat/pharmacology ; YAP-Signaling Proteins ; eIF-2 Kinase/genetics ; eIF-2 Kinase/metabolism