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المؤلفون: Annunziata D’Ercole, Lorenzo Pacini, Giuseppina Sabatino, Matteo Zini, Lorenzo Milli, Francesca Nuti, Arianna Ribecai, Alfredo Paio, Paolo Rovero, Anna Maria Papini
المصدر: Organic Process Research & Development. 26:2540-2540
مصطلحات موضوعية: Organic Chemistry, Physical and Theoretical Chemistry
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المؤلفون: Paolo Rovero, Alfredo Paio, Annunziata D’Ercole, Matteo Zini, Francesca Nuti, L. Pacini, Anna Maria Papini, Arianna Ribecai, Giuseppina Sabatino
المصدر: Organic process research & development 25 (2021): 2754–2771. doi:10.1021/acs.oprd.1c00368
info:cnr-pdr/source/autori:D'Ercole, Annunziata; Pacini, Lorenzo; Sabatino, Giuseppina; Zini, Matteo; Nuti, Francesca; Ribecai, Arianna; Paio, Alfredo; Rovero, Paolo; Papini, Anna Maria/titolo:An Optimized Safe Process from Bench to Pilot cGMP Production of API Eptifibatide Using a Multigram-Scale Microwave-Assisted Solid-Phase Peptide Synthesizer/doi:10.1021%2Facs.oprd.1c00368/rivista:Organic process research & development/anno:2021/pagina_da:2754/pagina_a:2771/intervallo_pagine:2754–2771/volume:25مصطلحات موضوعية: chemistry.chemical_classification, Materials science, Chromatography, technology transfer, Organic Chemistry, multigram-scale microwave-assisted peptide synthesis, Peptide, generic peptide drug, Microwave assisted, peptide production scale-up, peptide production pilot plant, chemistry, Phase (matter), generic peptide drug, peptide production scale-up, multigram-scale microwave-assisted peptide synthesis, technology transfer, peptide production pilot plant, Eptifibatide, medicine, Physical and Theoretical Chemistry, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29c2a766b49246c4ffd343dfd85a016
https://publications.cnr.it/doc/464122 -
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المؤلفون: L. Pacini, Annunziata D’Ercole, Matteo Zini, Alfredo Paio, Paolo Rovero, Anna Maria Papini, Giuseppina Sabatino, Arianna Ribecai
المصدر: Organic process research & development (2021). doi:10.1021/acs.oprd.0c00490
info:cnr-pdr/source/autori:Papini, Anna Maria; Sabatino, Giuseppina; D'Ercole, Annunziata; Pacini, Lorenzo; Zini, Matteo; Ribecai, Arianna; Paio, Alfredo; Rovero, Paolo/titolo:An optimized scalable fully automated solid-phase microwave-assisted cGMP-ready process for the preparation of eptifibatide/doi:10.1021%2Facs.oprd.0c00490/rivista:Organic process research & development/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volumeمصطلحات موضوعية: Materials science, Scale-up, Nanotechnology, active pharmaceutical ingredient, peptide, scale-up, oxidation, automated on-resin disulfide bond formation, off-resin disulfide bond formation, single reactor solid-phase synthesis, 010402 general chemistry, 01 natural sciences, Microwave assisted, chemistry.chemical_compound, Phase (matter), Oxidation, medicine, Peptide synthesis, Physical and Theoretical Chemistry, Active ingredient, 010405 organic chemistry, Organic Chemistry, Off-resin disulfide bond formation, 0104 chemical sciences, Fully automated, chemistry, Scientific method, Peptide, Single reactor solid-phase synthesis, Scalability, Eptifibatide, Active pharmaceutical ingredient, Automated on-resin disulfide bond formation, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c4b0fe2aba17e3983bfb82d507cdb0
http://hdl.handle.net/2158/1219739 -
4دورية أكاديمية
المؤلفون: Bruna DalPizol Novello, Marcela Maria Zanatta, Felipe Pompolim Mendes, Alfredo Paiola Albrecht, Arthur Arrobas Martins Barroso
المصدر: Acta Scientiarum: Biological Sciences, Vol 45, Iss 1 (2023)
مصطلحات موضوعية: genetic improvement, transgenic, sustainability, genetically modified organisms., Biology (General), QH301-705.5, Microbiology, QR1-502
وصف الملف: electronic resource
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المؤلفون: Daniele Donati, Stefano Biondi, Alfredo Paio, Stjepan Mutak, Sergio Lociuro, Elisa Piga, Francesca Cardullo, Dražen Pavlović, Daniele Andreotti
المصدر: ACS Medicinal Chemistry Letters. 5:1133-1137
مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Stereochemistry, Organic Chemistry, Telithromycin, Erythromycin, Biology, Biochemistry, In vitro, Macrolide Antibiotics, Microbiology, chemistry, Clarithromycin, Drug Discovery, medicine, Antibacterial activity, Ketolide, Lactone, medicine.drug
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المؤلفون: Daniele Donati, Francesca Cardullo, Carmela Napolitano, Stefano Manfredini, Alfredo Paio, Manuela Borriello
المصدر: Synthetic Communications. 41:2031-2035
مصطلحات موضوعية: Piperazine, chemistry.chemical_compound, chemistry, Organic Chemistry, Rapid access, Organic chemistry, Combinatorial chemistry
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المؤلفون: Daniele Andreotti, Roberto Profeta, Alfredo Paio, Simone Spada, Francesco Ferroni, Jens Klein
المصدر: Tetrahedron Letters. 51:5521-5524
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, Aryl, Organic Chemistry, Drug Discovery, Organic chemistry, Biochemistry, Octane
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المؤلفون: Daniele Donati, Manuela Borriello, Carmela Napolitano, Francesca Cardullo, Alfredo Paio, Stefano Manfredini
المصدر: Tetrahedron. 66:5492-5497
مصطلحات موضوعية: chemistry.chemical_classification, Heptane, Bicyclic molecule, Intramolecular reaction, Stereochemistry, Carboxylic acid, Organic Chemistry, Biochemistry, Chemical synthesis, chemistry.chemical_compound, chemistry, Drug Discovery, Lactam, Chemoselectivity, Imide
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المؤلفون: Giovanna Zinzalla, Carla Marchioro, Laura Casiraghi, Stefano Maiorana, Clara Baldoli, Elisabetta de Magistris, Pierfausto Seneci, and Alfredo Paio, Emanuela Licandro
المصدر: Journal of Combinatorial Chemistry. 5:809-813
مصطلحات موضوعية: Polymers, Ligand, chemistry.chemical_element, General Chemistry, Dichlorobenzene, Chromium, chemistry.chemical_compound, chemistry, Nucleophile, Chromium Compounds, Polymer chemistry, Technology, Pharmaceutical, Organic chemistry, Reactivity (chemistry), Polystyrene, Polymer supported
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المؤلفون: Gianna Reginato, Pierfausto Seneci, Sylvie Gehanne, Elena Grandini, Alfredo Paio
المصدر: Tetrahedron letters 44 (2003): 1867–1870. doi:10.1016/S0040-4039(03)00090-X
info:cnr-pdr/source/autori:Paio, Alfredo; Gehanne, Sylvie; Grandini, Elena; Reginato, Gianna; Seneci, Pierfausto/titolo:A new analytical method for anchoring quantification of amines on resin support/doi:10.1016%2FS0040-4039(03)00090-X/rivista:Tetrahedron letters/anno:2003/pagina_da:1867/pagina_a:1870/intervallo_pagine:1867–1870/volume:44مصطلحات موضوعية: Carbamate, medicine.medical_treatment, amines, Organic Chemistry, Anchoring, Chromophore, Biochemistry, loading, chemistry.chemical_compound, chemistry, Yield (chemistry), Drug Discovery, solid phase, medicine, Organic chemistry, Polystyrene, Linker