المؤلفون: Liu MY; Stem Cell Program, Division of Hematology/Oncology, and.; Division of Pulmonary and Critical Care Medicine and.; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin., Chen B; Stem Cell Program, Division of Hematology/Oncology, and., Borji M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts., Garcia de Alba Rivas C; Stem Cell Program, Division of Hematology/Oncology, and., Dost AFM; Stem Cell Program, Division of Hematology/Oncology, and.; Hubrecht Institute for Developmental Biology and Stem Cell Research, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands., Moye AL; Stem Cell Program, Division of Hematology/Oncology, and., Movval Abdulla N; Division of Pulmonary and Critical Care Medicine and., Paschini M; Stem Cell Program, Division of Hematology/Oncology, and., Rollins SD; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts.; Department of Medicine and., Wang R; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts.; Department of Medicine and., Schnapp LM; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin., Khalil HA; Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Medicine and., Sharma NS; Division of Pulmonary and Critical Care Medicine and.; Division of Pulmonary and Critical Care, Veterans Affairs Medical Center, West Roxbury, Boston, Massachusetts; and., Kim CF; Stem Cell Program, Division of Hematology/Oncology, and.; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, Massachusetts.; Department of Genetics, Harvard Medical School, Boston, Massachusetts.; Harvard Stem Cell Institute, Cambridge, Massachusetts.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Jun 15; Vol. 209 (12), pp. 1501-1504.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

مواضيع طبية MeSH: Organoids* , Bronchoalveolar Lavage Fluid*/cytology, Humans ; Pulmonary Alveoli/cytology ; Pulmonary Alveoli/pathology

المؤلفون: Dayton TL; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands; Oncode Institute, Hubrecht Institute, 3584 CT Utrecht, the Netherlands. Electronic address: talya.dayton@embl.es., Alcala N; Rare Cancers Genomics Team (RCG), Genomic Epidemiology Branch (GEM), International Agency for Research on Cancer/World Health Organisation (IARC/WHO), 69007 Lyon, France., Moonen L; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Centre, 6229 ER Maastricht, the Netherlands., den Hartigh L; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands., Geurts V; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands., Mangiante L; Rare Cancers Genomics Team (RCG), Genomic Epidemiology Branch (GEM), International Agency for Research on Cancer/World Health Organisation (IARC/WHO), 69007 Lyon, France., Lap L; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Centre, 6229 ER Maastricht, the Netherlands., Dost AFM; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands; Oncode Institute, Hubrecht Institute, 3584 CT Utrecht, the Netherlands., Beumer J; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands; Oncode Institute, Hubrecht Institute, 3584 CT Utrecht, the Netherlands., Levy S; Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands., van Leeuwaarde RS; Department of Endocrine Oncology, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Hackeng WM; Department of Pathology, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, the Netherlands., Samsom K; Department of Pathology, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands., Voegele C; Rare Cancers Genomics Team (RCG), Genomic Epidemiology Branch (GEM), International Agency for Research on Cancer/World Health Organisation (IARC/WHO), 69007 Lyon, France., Sexton-Oates A; Rare Cancers Genomics Team (RCG), Genomic Epidemiology Branch (GEM), International Agency for Research on Cancer/World Health Organisation (IARC/WHO), 69007 Lyon, France., Begthel H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands., Korving J; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands., Hillen L; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Centre, 6229 ER Maastricht, the Netherlands., Brosens LAA; Department of Pathology, University Medical Center Utrecht, Utrecht University, 3584 CX Utrecht, the Netherlands., Lantuejoul S; Department of Biopathology, Pathology Research Platform- Synergie Lyon Cancer- CRCL, Centre Léon Bérard Unicancer, 69008 Lyon, France; Université Grenoble Alpes, Grenoble, France., Jaksani S; Hubrecht Organoid Technology, Utrecht 3584 CM, the Netherlands., Kok NFM; Department of Surgery, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands., Hartemink KJ; Department of Surgery, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands., Klomp HM; Department of Surgery, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands., Borel Rinkes IHM; Department of Endocrine Surgical Oncology, University Medical Center Utrecht, Utrecht 3508 GA, the Netherlands., Dingemans AM; Department of Pulmonary Diseases, GROW School for Oncology and and Reproduction, Maastricht University Medical Centre, Maastricht, the Netherlands; Department of Pulmonary Medicine, Erasmus MC Cancer Institute, University Medical Center, Rotterdam 3015 GD, the Netherlands., Valk GD; Department of Endocrine Oncology, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Vriens MR; Department of Endocrine Surgical Oncology, University Medical Center Utrecht, Utrecht 3508 GA, the Netherlands., Buikhuisen W; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands., van den Berg J; Department of Pathology, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands., Tesselaar M; Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands., Derks J; Department of Pulmonary Diseases, GROW School for Oncology and and Reproduction, Maastricht University Medical Centre, Maastricht, the Netherlands., Speel EJ; Department of Pathology, GROW School for Oncology and Reproduction, Maastricht University Medical Centre, 6229 ER Maastricht, the Netherlands., Foll M; Rare Cancers Genomics Team (RCG), Genomic Epidemiology Branch (GEM), International Agency for Research on Cancer/World Health Organisation (IARC/WHO), 69007 Lyon, France., Fernández-Cuesta L; Rare Cancers Genomics Team (RCG), Genomic Epidemiology Branch (GEM), International Agency for Research on Cancer/World Health Organisation (IARC/WHO), 69007 Lyon, France. Electronic address: fernandezcuestal@iarc.who.int., Clevers H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584 CT Utrecht, the Netherlands; Oncode Institute, Hubrecht Institute, 3584 CT Utrecht, the Netherlands. Electronic address: h.clevers@hubrecht.eu.

المصدر: Cancer cell [Cancer Cell] 2023 Dec 11; Vol. 41 (12), pp. 2083-2099.e9.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Neuroendocrine Tumors*/drug therapy , Neuroendocrine Tumors*/genetics , Neuroendocrine Tumors*/metabolism , Carcinoma, Neuroendocrine*/drug therapy , Carcinoma, Neuroendocrine*/genetics , Carcinoma, Neuroendocrine*/metabolism , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Pancreatic Neoplasms*/pathology, Humans

المؤلفون: Li J; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Dang SM; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Schurmann P; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Department of Biology, Faculty of Science, Utrecht University, 3584 CH Utrecht, the Netherlands., Dost AFM; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Moye AL; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Paschini M; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Bhetariya PJ; Harvard Chan Bioinformatics Core, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115., Bronson R; Rodent Histopathology Core, Harvard Medical School, Boston, MA 02115, USA., Sui SJH; Harvard Chan Bioinformatics Core, Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115., Kim CF; Stem Cell Program, Division of Hematology/Oncology and Pulmonary & Respiratory Diseases, Children's Hospital Boston, Boston MA 02115 USA.; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

المصدر: Research square [Res Sq] 2023 Mar 14. Date of Electronic Publication: 2023 Mar 14.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

المؤلفون: Balážová K; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW & University Medical Centre Utrecht, Utrecht, Netherlands.; Oncode Institute, Hubrecht Institute-KNAW, Utrecht, Netherlands., Clevers H; Roche Pharma Research and early Development, Basel, Switzerland., Dost AFM; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW & University Medical Centre Utrecht, Utrecht, Netherlands.; Oncode Institute, Hubrecht Institute-KNAW, Utrecht, Netherlands.

المصدر: ELife [Elife] 2023 Feb 21; Vol. 12. Date of Electronic Publication: 2023 Feb 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/pathology , Antineoplastic Agents*/pharmacology, Animals ; Mice ; Coculture Techniques ; Macrophages ; Tumor Microenvironment

المؤلفون: Sainz de Aja J; From the, Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary & Respiratory Diseases, Boston Children's Hospital, Boston, MA, USA., Dost AFM; From the, Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary & Respiratory Diseases, Boston Children's Hospital, Boston, MA, USA., Kim CF; From the, Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary & Respiratory Diseases, Boston Children's Hospital, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.

المصدر: Journal of internal medicine [J Intern Med] 2021 May; Vol. 289 (5), pp. 629-635. Date of Electronic Publication: 2020 Dec 19.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8904841 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2796 (Electronic) Linking ISSN: 09546820 NLM ISO Abbreviation: J Intern Med Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma of Lung/*pathology , Cell Transformation, Neoplastic/*genetics , Lung Neoplasms/*pathology , Pulmonary Alveoli/*pathology , Stem Cells/*pathology, Adenocarcinoma of Lung/genetics ; Humans ; Lung Neoplasms/genetics ; Mutation ; Oncogenes/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; Pulmonary Alveoli/physiology

المؤلفون: Dost AFM; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Moye AL; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Vedaie M; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Tran LM; Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA, USA., Fung E; Department of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA, USA., Heinze D; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; Section of Gastroenterology and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Villacorta-Martin C; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA., Huang J; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Hekman R; Center for Network Systems Biology, Boston University, Boston, MA 02118, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA., Kwan JH; Center for Network Systems Biology, Boston University, Boston, MA 02118, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA., Blum BC; Center for Network Systems Biology, Boston University, Boston, MA 02118, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA., Louie SM; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Rowbotham SP; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Sainz de Aja J; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA., Piper ME; Harvard T.H. Chan School of Public Health, Department of Biostatistics, Boston, MA 02115, USA., Bhetariya PJ; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Harvard T.H. Chan School of Public Health, Department of Biostatistics, Boston, MA 02115, USA., Bronson RT; Rodent Histopathology Core, Harvard Medical School, Boston, MA 02115, USA., Emili A; Center for Network Systems Biology, Boston University, Boston, MA 02118, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA; Department of Biology, Boston University, Boston, MA 02215, USA., Mostoslavsky G; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; Section of Gastroenterology and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Fishbein GA; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095, USA., Wallace WD; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90033, USA., Krysan K; Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA, USA., Dubinett SM; Department of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA., Yanagawa J; Department of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: jyanagawa@mednet.ucla.edu., Kotton DN; Center for Regenerative Medicine of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: dkotton@bu.edu., Kim CF; Stem Cell Program and Divisions of Hematology/Oncology and Pulmonary Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: carla.kim@childrens.harvard.edu.

المصدر: Cell stem cell [Cell Stem Cell] 2020 Oct 01; Vol. 27 (4), pp. 663-678.e8. Date of Electronic Publication: 2020 Sep 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells* , Organoids*, Animals ; Humans ; Lung ; Mice ; Proteomics ; Proto-Oncogene Proteins p21(ras)/genetics

المؤلفون: Bleu M; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland., Gaulis S; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland.; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Basel, Switzerland., Lopes R; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland., Sprouffske K; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland., Apfel V; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland., Holwerda S; Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Basel, Switzerland., Pregnolato M; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland.; Friedrich Miescher Institute for Biomedical Research and University of Basel, Basel, Switzerland., Yildiz U; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland.; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Cordoʹ V; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland.; Prinses Maxima Center for Pediatric Oncology, Utrecht, Netherlands., Dost AFM; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland.; Stem cell program, Children's Hospital Boston and Department of Genetics, Harvard Medical School, Boston, USA., Knehr J; Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland., Carbone W; Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland., Lohmann F; Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland.; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Basel, Switzerland., Lin CY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Bradner JE; Novartis Institutes for Biomedical Research, Cambridge, MA, USA., Kauffmann A; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland., Tordella L; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland., Roma G; Chemical Biology & Therapeutics, Novartis Institutes for Biomedical Research, Basel, Switzerland., Galli GG; Disease Area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland. giorgio.galli@novartis.com.

المصدر: Nature communications [Nat Commun] 2019 Aug 20; Vol. 10 (1), pp. 3739. Date of Electronic Publication: 2019 Aug 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Renal Cell/*genetics , Ceruloplasmin/*genetics , Enhancer Elements, Genetic/*genetics , Gene Expression Regulation, Neoplastic/*genetics , Kidney Neoplasms/*genetics , PAX8 Transcription Factor/*genetics, Acetylation ; Biomarkers, Tumor/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Ceruloplasmin/metabolism ; Histones/metabolism ; Humans ; Promoter Regions, Genetic/genetics ; RNA Interference ; RNA, Small Interfering/genetics

المؤلفون: Rowbotham SP; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Li F; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, 10016, USA., Dost AFM; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Louie SM; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Marsh BP; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Pessina P; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Anbarasu CR; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Brainson CF; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, 40536, USA., Tuminello SJ; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Lieberman A; Department of Cancer Biology, Perelman School of Medicine at the University of Pennsylvania, Abramson Cancer Center, Philadelphia, PA, 19104, USA., Ryeom S; Department of Cancer Biology, Perelman School of Medicine at the University of Pennsylvania, Abramson Cancer Center, Philadelphia, PA, 19104, USA., Schlaeger TM; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA., Aronow BJ; Division of Biomedical Informatics, Cincinnati Children's Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Watanabe H; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Wong KK; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, 10016, USA., Kim CF; Stem Cell Program, Division of Hematology/Oncology and Pulmonary and Respiratory Diseases, Children's Hospital Boston, Boston, MA, 02115, USA. carla.kim@childrens.harvard.edu.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA. carla.kim@childrens.harvard.edu.; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA. carla.kim@childrens.harvard.edu.

المصدر: Nature communications [Nat Commun] 2018 Nov 19; Vol. 9 (1), pp. 4559. Date of Electronic Publication: 2018 Nov 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Disease Progression*, Histone Demethylases/*metabolism , Histone Methyltransferases/*metabolism , Lung Neoplasms/*metabolism, Adenocarcinoma of Lung/metabolism ; Animals ; Carcinogenesis ; Cell Line, Tumor/drug effects ; Cell Survival ; Disease Models, Animal ; Extracellular Matrix/genetics ; Histone Demethylases/drug effects ; Histone-Lysine N-Methyltransferase/drug effects ; Histone-Lysine N-Methyltransferase/metabolism ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Organoids/anatomy & histology ; Phenotype ; Proto-Oncogene Proteins p21(ras)/genetics