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المؤلفون: Hyo Sook Han, Jean Pierre Ayoub, Shannon Puhalla, Erik Jakobsen, Yaroslav Shparyk, David Maag, Igor Bondarenko, Marketa Palacova, Christine K. Ratajczak, Hans Wildiers, Michael Friedlander, Nikhil Khandelwal, Cristina Oprean, Madan G. Kundu, Yeon Hee Park, Mario Campone, Banu Arun, Mathilde Jalving, Eduardo Yanez, Bella Kaufman, Matthew W. Dudley, Véronique Diéras
المساهمون: Targeted Gynaecologic Oncology (TARGON), Centre Eugène Marquis (CRLCC), Tel Aviv University [Tel Aviv], University Medical Center Groningen [Groningen] (UMCG), Victor Babeş University of Medicine and Pharmacy (UMFT), Masaryk Memorial Cancer Institute (RECAMO), Universidad de la frontera [Chile], The University of Texas M.D. Anderson Cancer Center [Houston]
المصدر: Lancet Oncology, 21(10), 1269-1282. ELSEVIER SCIENCE INC
Lancet Oncology
Lancet Oncology, Elsevier, 2020, 21, pp.1269-1282. ⟨10.1016/S1470-2045(20)30447-2⟩
Diéras, V, Han, H S, Kaufman, B, Wildiers, H, Friedlander, M, Ayoub, J P, Puhalla, S L, Bondarenko, I, Campone, M, Jakobsen, E H, Jalving, M, Oprean, C, Palácová, M, Park, Y H, Shparyk, Y, Yañez, E, Khandelwal, N, Kundu, M G, Dudley, M, Ratajczak, C K, Maag, D & Arun, B K 2020, ' Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3) : a randomised, double-blind, placebo-controlled, phase 3 trial ', The Lancet Oncology, vol. 21, no. 10, pp. 1269-1282 . https://doi.org/10.1016/S1470-2045(20)30447-2مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Veliparib, Drug-Related Side Effects and Adverse Reactions, Organoplatinum Compounds, Paclitaxel, [SDV]Life Sciences [q-bio], Population, Genes, BRCA2, Genes, BRCA1, Breast Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors, Placebo, Drug Administration Schedule, Carboplatin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, Double-Blind Method, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Progression-free survival, education, Germ-Line Mutation, education.field_of_study, business.industry, BRCA mutation, Middle Aged, medicine.disease, Progression-Free Survival, 3. Good health, 030104 developmental biology, Treatment Outcome, chemistry, Response Evaluation Criteria in Solid Tumors, 030220 oncology & carcinogenesis, Benzimidazoles, Female, business
وصف الملف: application/pdf
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المؤلفون: Hans Wildiers, Véronique Diéras, Yaroslav Shparyk, Cristina Oprean, Erik Jakobsen, Michael Friedlander, Shannon Puhalla, M. Campone, Younghee Park, Hyo S. Han, Mathilde Jalving, Eduardo Yanez, Bella Kaufman, Banu Arun, I. Bondarenko, David Maag, Christine K. Ratajczak, Matthew W. Dudley, Marketa Palacova, J.P. Ayoub
المساهمون: Targeted Gynaecologic Oncology (TARGON)
المصدر: Annals of Oncology, 30, 857-858. Oxford University Press
Dieras, V C, Han, H S, Kaufman, B, Wildiers, H, Friedlander, M, Ayoub, J-P, Puhalla, S L, Bondarenko, I, Campone, M, Jakobsen, E H, Jalving, M, Oprean, C, Palacova, M, Park, Y H, Shparyk, Y, Yanez, E, Dudley, M, Ratajczak, C K, Maag, D & Arun, B K 2019, ' Phase III study of veliparib with carboplatin and paclitaxel in HER2-negative advanced/metastatic gBRCA-associated breast cancer ', Annals of Oncology, vol. 30, no. Suppl. 5, LBA9, pp. 857-858 . https://doi.org/10.1093/annonc/mdz394.008مصطلحات موضوعية: Oncology, medicine.medical_specialty, Veliparib, Surrogate endpoint, business.industry, Hematology, Neutropenia, medicine.disease, Chemotherapy regimen, Carboplatin, chemistry.chemical_compound, Breast cancer, chemistry, Paclitaxel, Internal medicine, medicine, Progression-free survival, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c5a8373a32ca232d0d8bead43e7919
https://research.rug.nl/en/publications/acdc7db2-ed8e-45e8-9245-4d37956c9c3a -
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المؤلفون: Julie M Scott, D'Ambra Dent, Matthew W. Dudley, Gayathri Ravi, Debra Wujcik, Kelly N. Godby, William N. Dudley, Smith Giri, Stacey A. Ingram, Luciano J. Costa, Susan Bal
المصدر: Blood. 138:5019-5019
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Immunology, Geriatric assessment, Cell Biology, Hematology, medicine.disease, Real world evidence, Biochemistry, Clinical Practice, Medicine, business, Intensive care medicine, Multiple myeloma
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1691852d538c0d81af6611a65cf19144
https://doi.org/10.1182/blood-2021-153753 -
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المؤلفون: Stacey A. Ingram, Debra Wujcik, Omer Jamy, Julie M Scott, Matthew W. Dudley, William N. Dudley, D'Ambra Dent
المصدر: Blood. 138:4050-4050
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Immunology, Personalized treatment, Geriatric assessment, Cell Biology, Hematology, medicine.disease, Biochemistry, law.invention, Myelogenous, Leukemia, Touchscreen, law, medicine, Intensive care medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d746edfb00b5a62853908b5539381df9
https://doi.org/10.1182/blood-2021-148806 -
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المؤلفون: Philip Komarnitsky, Matthew W. Dudley, Dustin A. Deming, Samuel Y Ngan, Brian G. Czito, Lei He, Mary F. Mulcahy, Wijith Munasinghe, Angela DeLuca, John Zalcberg, Kyle D. Holen, Rajendar K. Mittapalli, Michael Michael, Houman Vaghefi, Gayle S. Jameson
المصدر: The Lancet Gastroenterology & Hepatology. 2:418-426
مصطلحات موضوعية: Adult, Diarrhea, Male, 0301 basic medicine, medicine.medical_specialty, Maximum Tolerated Dose, Veliparib, medicine.medical_treatment, Antineoplastic Agents, Adenocarcinoma, Poly(ADP-ribose) Polymerase Inhibitors, Capecitabine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, Fatigue, Neoadjuvant therapy, Aged, Neoplasm Staging, Hepatology, Rectal Neoplasms, business.industry, Gastroenterology, Nausea, Chemoradiotherapy, Middle Aged, Total mesorectal excision, Neoadjuvant Therapy, Oxaliplatin, Surgery, Radiation therapy, 030104 developmental biology, Tolerability, chemistry, 030220 oncology & carcinogenesis, Benzimidazoles, Female, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0c3298d5aff4be85deed3990e6975d
https://doi.org/10.1016/s2468-1253(17)30012-2 -
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المؤلفون: Peter Ansell, Andrea E. Wahner Hendrickson, Rutger H. T. Koornstra, Scott H. Kaufmann, Matthew W. Dudley, Jourik A. Gietema, Krista M. Goergen, X. Wei Meng, Matthew J. Maurer, Karen S. Flatten, Carla D. Van Herpen, Martha W. den Hollander, Ann L. Oberg, Rachel M. Hurley, Agnes Jager, Maja J.A. de Jonge, Maria I. Harrell, Jill M. Wagner, Elizabeth M. Swisher, Stacie Peacock Shepherd, Daniel W. Visscher, Vivian Negron
المساهمون: Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Medical Oncology
المصدر: Gynecologic Oncology, 153, 127-134
Gynecologic Oncology, 153(1), 127-134. ACADEMIC PRESS INC ELSEVIER SCIENCE
Gynecologic Oncology, 153, 1, pp. 127-134
Gynecologic Oncology, 153(1), 127-134. Academic Pressمصطلحات موضوعية: 0301 basic medicine, DNA Repair, Genes, BRCA2, Genes, BRCA1, Poly (ADP-Ribose) Polymerase-1, RAD51, MULTICENTER, Cancer development and immune defence Radboud Institute for Health Sciences [Radboudumc 2], 0302 clinical medicine, PARP1, Medicine, Homologous Recombination, PARP inhibitors, Ovarian Neoplasms, Sulfonamides, Obstetrics and Gynecology, HR-deficiency, OPEN-LABEL, 53BP1, POLYMERASE INHIBITORS, Oncology, NIRAPARIB, 030220 oncology & carcinogenesis, Benzamides, PARP inhibitor, Female, Tumor Suppressor p53-Binding Protein 1, Rare cancers Radboud Institute for Health Sciences [Radboudumc 9], CARCINOMA, DNA repair, Poly(ADP-ribose) Polymerase Inhibitors, Article, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Ovarian cancer, Cell Line, Tumor, Carcinoma, Humans, Clonogenic assay, REPAIR, business.industry, MUTATIONS, DNA Repair Pathway, medicine.disease, PROFICIENT, 030104 developmental biology, Drug Resistance, Neoplasm, CELLS, Cancer research, DNA damage, business, RESISTANCE
وصف الملف: application/pdf
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المؤلفون: William N. Dudley, Debra Wujcik, Matthew W. Dudley, Amitkumar Mehta, Rachel Corona, Felice Cook
المصدر: Journal of Clinical Oncology. 38:e24192-e24192
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, business.industry, Treatment options, Cancer, medicine.disease, Patient preference, Non-Hodgkin's lymphoma, Lymphoma, Clinical Practice, Oncology, medicine, Intensive care medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9a0c189f13c1891e2b01f4acdb17ba23
https://doi.org/10.1200/jco.2020.38.15_suppl.e24192 -
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المؤلفون: Matthew W. Dudley, Hyo S. Han, Bruce A. Bach, Hans Wildiers, Michael Friedlander, Madan Gopal Kundu, Bella Kaufman, Jean-Pierre M. Ayoub, Christine K. Ratajczak, Banu Arun, Véronique Diéras, David Maag, Shannon Puhalla
المصدر: Journal of Clinical Oncology. 38:1091-1091
مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Veliparib, Combination therapy, business.industry, Advanced breast, Cancer, medicine.disease, Carboplatin/paclitaxel, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Internal medicine, PARP inhibitor, Medicine, In patient, business, 030215 immunology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::573bd6940849c51fb6729b3c1a9a52c4
https://doi.org/10.1200/jco.2020.38.15_suppl.1091 -
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المؤلفون: Ui Son, Debra Wujcik, Matthew W. Dudley, Valerie Lawhon, William N. Dudley, Margaret Kasner, Nikolaos Papadantonakis, Sarah A Wall, Stacey A. Ingram, Omer Jamy
المصدر: Journal of Clinical Oncology. 38:e24030-e24030
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, business.industry, media_common.quotation_subject, Personalized treatment, Geriatric assessment, Disease, medicine.disease, law.invention, Clinical Practice, Presentation, Leukemia, Myelogenous, Touchscreen, Oncology, law, Medicine, business, Intensive care medicine, media_common
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2253e439a9311a70ca2e76dc5142f7c5
https://doi.org/10.1200/jco.2020.38.15_suppl.e24030 -
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المؤلفون: Hyo S. Han, Hans Wildiers, Jean-Pierre M. Ayoub, Bella Kaufman, Véronique Diéras, Bruce A. Bach, Michael Friedlander, Matthew W. Dudley, David Maag, Christine K. Ratajczak, Shannon Puhalla, Banu Arun
المصدر: Cancer Research. 80:PD4-01
مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Veliparib, Population, Placebo, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, Internal medicine, Medicine, education, education.field_of_study, business.industry, Hazard ratio, Cancer, medicine.disease, Metastatic breast cancer, Carboplatin, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3837ed24d6d13d9379e059493ddb283f
https://doi.org/10.1158/1538-7445.sabcs19-pd4-01