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1دورية أكاديمية
المؤلفون: Wenyang Li, Jennifer Y Chen, Cheng Sun, Robert P Sparks, Lorena Pantano, Raza-Ur Rahman, Sean P Moran, Joshua V Pondick, Rory Kirchner, David Wrobel, Michael Bieler, Achim Sauer, Shannan J Ho Sui, Julia F Doerner, Jörg F Rippmann, Alan C Mullen
المصدر: eLife, Vol 11 (2022)
مصطلحات موضوعية: nanchangmycin, liver fibrosis, hepatic stellate cells, compound screening, FYN, collagen, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Thomas Fox, Michael Bieler, Peter Haebel, Rodrigo Ochoa, Stefan Peters, Alexander Weber
المصدر: Journal of Chemical Information and Modeling. 62:3942-3947
مصطلحات موضوعية: General Chemical Engineering, Humans, General Chemistry, Library and Information Sciences, Peptides, Computer Science Applications
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3
المؤلفون: Yang Yang, Daniela M. Santos, Lorena Pantano, Rachel Knipe, Elizabeth Abe, Amanda Logue, Gina Pronzati, Katharine E. Black, Jillian J. Spinney, Francesca Giacona, Michael Bieler, Cedrickx Godbout, Paul Nicklin, David Wyatt, Andrew M. Tager, Peter Seither, Franziska E. Herrmann, Benjamin D. Medoff
المصدر: Am J Respir Cell Mol Biol
مصطلحات موضوعية: Cell Nucleus, Pulmonary and Respiratory Medicine, Pulmonary Fibrosis, Clinical Biochemistry, Cell Cycle Proteins, YAP-Signaling Proteins, Cell Biology, Fibroblasts, Phosphoproteins, Idiopathic Pulmonary Fibrosis, Mice, Transforming Growth Factor beta, Animals, Humans, Molecular Biology, Original Research, Adaptor Proteins, Signal Transducing, Aurora Kinase A
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fada14bae95a8a79f19d9635326a85
https://doi.org/10.1165/rcmb.2021-0428oc -
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المؤلفون: Wenyang Li, Jennifer Y Chen, Cheng Sun, Robert P Sparks, Lorena Pantano, Raza-Ur Rahman, Sean P Moran, Joshua V Pondick, Rory Kirchner, David Wrobel, Michael Bieler, Achim Sauer, Shannan J Ho Sui, Julia F Doerner, Jörg F Rippmann, Alan C Mullen
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d33dd97295a9b2bb9f0b58f0add2c065
https://doi.org/10.7554/elife.74513.sa2 -
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المؤلفون: Wenyang Li, Jennifer Y Chen, Cheng Sun, Robert P Sparks, Lorena Pantano, Raza-Ur Rahman, Sean P Moran, Joshua V Pondick, Rory Kirchner, David Wrobel, Michael Bieler, Achim Sauer, Shannan J Ho Sui, Julia F Doerner, Jörg F Rippmann, Alan C Mullen
المصدر: eLife. 11
مصطلحات موضوعية: Liver Cirrhosis, Mitogen-Activated Protein Kinase 1, Extracellular Matrix Proteins, General Immunology and Microbiology, General Neuroscience, General Medicine, Fibrosis, General Biochemistry, Genetics and Molecular Biology, Cicatrix, Focal Adhesion Kinase 1, Hepatic Stellate Cells, Humans, Spiro Compounds, Collagen, Ethers
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6
المؤلفون: Royale Nichols, Jillian J Spinney, Michael Bieler, Katharine E. Black, Yufei Lin, Lida P. Hariri, Clemens K. Probst, Paul Nicklin, Benjamin D. Medoff, Lorena Pantano, Paula Grasberger, Peter Seither, David Wyatt, Daniela M. Santos, Gina Pronzati, Andrew M. Tager
المصدر: Am J Respir Cell Mol Biol
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Cytoplasm, Simvastatin, Pulmonary Fibrosis, Clinical Biochemistry, Mevalonic Acid, Cell Cycle Proteins, Bleomycin, Small Molecule Libraries, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Mice, Fibrosis, Pulmonary fibrosis, medicine, Animals, Humans, Fibroblast, Molecular Biology, Original Research, Adaptor Proteins, Signal Transducing, Cell Nucleus, Hippo signaling pathway, biology, business.industry, YAP-Signaling Proteins, Cell Biology, Fibroblasts, medicine.disease, Phosphoproteins, medicine.anatomical_structure, chemistry, HMG-CoA reductase, biology.protein, Cancer research, Mevalonate pathway, Acyl Coenzyme A, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, Biomarkers, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69e7ff705685e150c6c5d62f81c340b
https://europepmc.org/articles/PMC7110981/ -
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المؤلفون: Jan M. Kriegl, Petra Schneider, Michael Bieler, Gisbert Schneider, Michael Reutlinger, Tiago Rodrigues
المصدر: Molecular Informatics. 35:192-198
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Databases, Pharmaceutical, Computer science, Normal Distribution, Quantitative Structure-Activity Relationship, Machine learning, computer.software_genre, 01 natural sciences, Receptors, G-Protein-Coupled, Machine Learning, Small Molecule Libraries, Set (abstract data type), 03 medical and health sciences, symbols.namesake, Structural Biology, Kriging, Drug Discovery, Combinatorial Chemistry Techniques, Gaussian process, Virtual screening, 010405 organic chemistry, business.industry, Ant colony optimization algorithms, Organic Chemistry, Usability, chEMBL, 0104 chemical sciences, Computer Science Applications, Data set, 030104 developmental biology, Drug Design, symbols, Molecular Medicine, Data mining, Artificial intelligence, business, computer
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المؤلفون: Herbert Koeppen, Michael Bieler
المصدر: Drug Development Research. 73:357-364
مصطلحات موضوعية: business.industry, Computer science, Phenotypic screening, Adverse drug effects, Computational biology, Bioinformatics, Chemical space, chemistry.chemical_compound, chemistry, Drug Discovery, Chemogenomics, Polypharmacology, Pharmaceutical sciences, business, Pharmaceutical industry
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المؤلفون: Michael Bieler, Peter Gierschik, Simone Kredel, Silke Hobbie, Michael Wolff, Ralf Heilker
المصدر: SLAS Discovery. 16:683-693
مصطلحات موضوعية: CCR2, Receptors, CCR2, animal diseases, media_common.quotation_subject, Intracellular Space, CCL4, Pharmacology, Biology, Biochemistry, CCL8, Monocytes, Analytical Chemistry, Inhibitory Concentration 50, Chemokine receptor, Cell Line, Tumor, parasitic diseases, medicine, Humans, CXCL10, Internalization, Receptor, Chemokine CCL2, Fluorescent Dyes, media_common, Automation, Laboratory, Staining and Labeling, Monocyte, hemic and immune systems, High-Throughput Screening Assays, Protein Transport, medicine.anatomical_structure, Molecular Medicine, Protein Binding, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3a50d23cde6996d532fbaa1286340a
https://doi.org/10.1177/1087057111406884 -
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المؤلفون: Ralf Heilker, Gisbert Schneider, Michael Bieler, Herbert Köppen
المصدر: Journal of Chemical Information and Modeling. 51:1897-1905
مصطلحات موضوعية: Models, Molecular, Chemistry, Pharmaceutical, General Chemical Engineering, Computational biology, Library and Information Sciences, Biology, Ligands, computer.software_genre, Receptors, G-Protein-Coupled, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Similarity (network science), Drug Discovery, Chemogenomics, Humans, Computer Simulation, Amino Acid Sequence, Databases, Protein, Binding Sites, Dose-Response Relationship, Drug, Macromolecular drug, Genomics, General Chemistry, Computer Science Applications, Models, Chemical, Pharmaceutical Preparations, chemistry, Drug Design, Data mining, computer, Algorithms, Protein Binding