المؤلفون: Soleimani Asl S; Iran Digital Twin Laboratory (IDT-Lab)- Incubator Center, Iran University of Science and Technology, Tehran, Iran., Roozbahani MH; School of Advanced Technologies, Iran University of Science and Technology, Tehran, Iran.

المصدر: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Aug; Vol. 42 (13), pp. 6863-6870. Date of Electronic Publication: 2023 Aug 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Docking Simulation* , Molecular Dynamics Simulation* , COVID-19 Drug Treatment* , SARS-CoV-2*/drug effects , SARS-CoV-2*/enzymology , Papain*/antagonists & inhibitors , Papain*/chemistry , Papain*/metabolism , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Chlorogenic Acid*/chemistry , Chlorogenic Acid*/pharmacology , Catalytic Domain*, Humans ; Coronavirus Papain-Like Proteases/antagonists & inhibitors ; Coronavirus Papain-Like Proteases/chemistry ; Coronavirus Papain-Like Proteases/metabolism ; Coronavirus 3C Proteases/antagonists & inhibitors ; Coronavirus 3C Proteases/chemistry ; Coronavirus 3C Proteases/metabolism ; COVID-19/virology ; Protein Binding ; Binding Sites ; Protease Inhibitors/pharmacology ; Protease Inhibitors/chemistry

المؤلفون: van Huizen M; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Bloeme-Ter Horst JR; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., de Gruyter HLM; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Geurink PP; Department of Cell and Chemical Biology, Division of Chemical Biology and Drug Discovery, Leiden University Medical Centre, Leiden, The Netherlands., van der Heden van Noort GJ; Department of Cell and Chemical Biology, Division of Chemical Biology and Drug Discovery, Leiden University Medical Centre, Leiden, The Netherlands., Knaap RCM; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Nelemans T; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Ogando NS; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Leijs AA; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Urakova N; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Mark BL; Department of Microbiology, University of Manitoba, Winnipeg, Canada., Snijder EJ; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Myeni SK; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands., Kikkert M; Molecular Virology Laboratory, Leiden University Center of Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, Netherlands.

المصدر: PLoS pathogens [PLoS Pathog] 2024 Mar 25; Vol. 20 (3), pp. e1012100. Date of Electronic Publication: 2024 Mar 25 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: Coronavirus Papain-Like Proteases*/genetics , COVID-19*, Humans ; Animals ; Mice ; SARS-CoV-2/metabolism ; Immunity, Innate ; Papain/genetics ; Papain/metabolism ; Peptide Hydrolases/metabolism ; Virus Replication ; Polyproteins

المؤلفون: Brian Chia CS; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, Chromos #08-01, Singapore, 138670, Singapore., Pheng Lim S; Experimental Drug Development Centre (EDDC), Agency for Science, Technology and Research (A*STAR), 10 Biopolis Road, Chromos #08-01, Singapore, 138670, Singapore.

المصدر: ChemMedChem [ChemMedChem] 2023 Aug 15; Vol. 18 (16), pp. e202300216. Date of Electronic Publication: 2023 Jun 15.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Papain* , COVID-19*, Humans ; Peptide Hydrolases ; Coronavirus Papain-Like Proteases ; SARS-CoV-2 ; Antiviral Agents/pharmacology ; Protease Inhibitors/pharmacology

المؤلفون: González RD; CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.; CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra 3004-504, Portugal.; Institute for Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), University of Coimbra, Coimbra 3030-789, Portugal., Carvalho ATP; CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.; CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra 3004-504, Portugal.; Almac Sciences, Department of Biocatalysis and Isotope Chemistry, Almac House, 20 Seagoe Industrial Estate ,Craigavon, Northern Ireland BT63 5QD, United Kingdom.

المصدر: The journal of physical chemistry. B [J Phys Chem B] 2024 Aug 08; Vol. 128 (31), pp. 7500-7512. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE

مواضيع طبية MeSH: Peptide Nucleic Acids*/chemistry , Papain*/chemistry , Papain*/metabolism , Water*/chemistry , Solvents*/chemistry , Peptides*/chemistry , Density Functional Theory*, Molecular Dynamics Simulation

المؤلفون: Liu Y; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China., Chen Z; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China., Cheng S; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China., Zhai M; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China., Ma F; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China., Nian Y; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China.; Key Laboratory of Meat Processing and Quality Control, MOE, Key Laboratory of Meat Processing, MOA, Jiangsu Synergetic Innovation Center of Meat Processing and Quality Control, Nanjing Agricultural University, Nanjing, Jiangsu 210095, P. R. China., Ding L; Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach 8603, Switzerland., Hu B; College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, Nanjing, Jiangsu 210095, P. R. China.

المصدر: ACS nano [ACS Nano] 2024 Jul 09; Vol. 18 (27), pp. 17969-17986. Date of Electronic Publication: 2024 Jun 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

مواضيع طبية MeSH: Obesity*/metabolism , Papain*/metabolism , Papain*/chemistry, Animals ; Mice ; Bromelains/pharmacology ; Bromelains/chemistry ; Bromelains/metabolism ; Mice, Inbred C57BL ; Male ; Diet, High-Fat ; Emulsions/chemistry ; Adipose Tissue/metabolism ; Adipose Tissue/drug effects ; Lipid Metabolism/drug effects

المؤلفون: Li K; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China., Li Z; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China., Zhang J; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China., Wang J; Shandong Nanshan Zhishang Technology Co., Ltd., Longkou, China., Yu Y; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China., Zhou M; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China., Wang Q; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China., Wang P; Key Laboratory of Science and Technology of Eco-Textile, Ministry of Education, Jiangnan University, Wuxi, China. Electronic address: pwang@jiangnan.edu.cn.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jul; Vol. 273 (Pt 2), pp. 133156. Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: Papain*/chemistry , Wool*/chemistry , Disulfides*/chemistry, Animals ; Reducing Agents/chemistry ; Sulfites/chemistry ; Sulfites/pharmacology ; Phosphines/chemistry ; Wool Fiber ; Hydrolysis ; Textiles

المؤلفون: Abdel-Ghani MA; Department of Clinical Sciences, College of Veterinary Medicine, King Faisal University, AL-Ahsa, Saudi Arabia.; Department of Theriogenology, Faculty of Veterinary Medicine, Assuit University, Assuit, Egypt., Ghoneim IM; Department of Clinical Sciences, College of Veterinary Medicine, King Faisal University, AL-Ahsa, Saudi Arabia., Nagano M; Laboratory of Animal Reproduction, Department of Animal Science, School of Veterinary Medicine, Kitasato University, Towada, Japan., AlMomen HQM; Ministry of Agriculture, AL-Ahsa, Saudi Arabia.

المصدر: Reproduction in domestic animals = Zuchthygiene [Reprod Domest Anim] 2024 Jun; Vol. 59 (6), pp. e14637.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Paul Parey Scientific Publishers Country of Publication: Germany NLM ID: 9015668 Publication Model: Print Cited Medium: Internet ISSN: 1439-0531 (Electronic) Linking ISSN: 09366768 NLM ISO Abbreviation: Reprod Domest Anim Subsets: MEDLINE

مواضيع طبية MeSH: Papain*/pharmacology , Camelus* , Sperm Motility*/drug effects , Semen*/drug effects , Semen Preservation*/veterinary , Semen Preservation*/methods, Animals ; Male ; Viscosity ; Semen Analysis/veterinary ; Spermatozoa/drug effects ; Spermatozoa/physiology ; Acrosome/drug effects

المؤلفون: Li X; Key Laboratory of Modern Analytical Science and Separation Technology of Fujian Province, Key Laboratory of Pollution Monitoring and Control of Fujian Province, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou 363000, People's Republic of China., Lu X; Key Laboratory of Modern Analytical Science and Separation Technology of Fujian Province, Key Laboratory of Pollution Monitoring and Control of Fujian Province, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou 363000, People's Republic of China., Zhang L; Key Laboratory of Modern Analytical Science and Separation Technology of Fujian Province, Key Laboratory of Pollution Monitoring and Control of Fujian Province, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou 363000, People's Republic of China., Cai Z; Key Laboratory of Modern Analytical Science and Separation Technology of Fujian Province, Key Laboratory of Pollution Monitoring and Control of Fujian Province, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou 363000, People's Republic of China. Electronic address: czx1816@mnnu.edu.cn., Tang D; Key Laboratory of Analysis and Detection for Food Safety (Ministry of Education & Fujian Province), Institute of Nanomedicine and Nanobiosensing, Department of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China., Lai W; Key Laboratory of Modern Analytical Science and Separation Technology of Fujian Province, Key Laboratory of Pollution Monitoring and Control of Fujian Province, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, Zhangzhou 363000, People's Republic of China. Electronic address: wenqiang.lai@mnnu.edu.cn.

المصدر: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2024 Jul 05; Vol. 315, pp. 124269. Date of Electronic Publication: 2024 Apr 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoembryonic Antigen*/analysis , Colorimetry*/methods , Papain*/metabolism , Limit of Detection*, Immunoassay/methods ; Humans ; Glucose Oxidase/chemistry ; Glucose Oxidase/metabolism ; Hydrogen Peroxide/chemistry ; Catalysis ; Benzidines/chemistry ; Biosensing Techniques/methods ; Reproducibility of Results

المؤلفون: Santos LH; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Kronenberger T; Department of Oncology and Pneumonology, Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Straße 10, DE72076 Tübingen, Germany.; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland.; Institute of Pharmacy, Pharmaceutical/Medicinal Chemistry and Tübingen Center for Academic Drug Discovery (TüCAD2), Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Almeida RG; Institute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Silva EB; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., Rocha REO; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Oliveira JC; Institute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Barreto LV; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Skinner D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., Fajtová P; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States.; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 16610 Prague, Czech Republic., Giardini MA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., Woodworth B; Department of Medicine, Division of Infectious Diseases, University of California San Diego, La Jolla, California 92093, United States., Bardine C; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94143, United States., Lourenço AL; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94143, United States., Craik CS; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94143, United States., Poso A; Department of Oncology and Pneumonology, Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Straße 10, DE72076 Tübingen, Germany.; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland., Podust LM; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., McKerrow JH; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., Siqueira-Neto JL; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., O'Donoghue AJ; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093-0657, United States., da Silva Júnior EN; Institute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil., Ferreira RS; Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.

المصدر: Journal of chemical information and modeling [J Chem Inf Model] 2022 Dec 26; Vol. 62 (24), pp. 6553-6573. Date of Electronic Publication: 2022 Aug 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Naphthoquinones*/chemistry , Naphthoquinones*/pharmacology , Protease Inhibitors*/pharmacology , Protease Inhibitors*/chemistry , SARS-CoV-2*/drug effects , SARS-CoV-2*/enzymology , Coronavirus 3C Proteases*/antagonists & inhibitors , Coronavirus Papain-Like Proteases*/antagonists & inhibitors, Humans ; COVID-19 ; Molecular Docking Simulation ; Papain

المؤلفون: Ullrich S; Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia., Nitsche C; Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia.

المصدر: Chembiochem : a European journal of chemical biology [Chembiochem] 2022 Oct 06; Vol. 23 (19), pp. e202200327. Date of Electronic Publication: 2022 Sep 08.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

مواضيع طبية MeSH: Papain*/chemistry , Papain*/metabolism , COVID-19 Drug Treatment*, Aniline Compounds ; Antiviral Agents/chemistry ; Benzamides ; Coronavirus Papain-Like Proteases ; Humans ; Naphthalenes ; Peptide Hydrolases/metabolism ; Protease Inhibitors/pharmacology ; SARS-CoV-2 ; Ubiquitin/metabolism ; Viral Proteins/chemistry