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1دورية أكاديمية
المؤلفون: Philip M. Zakas, John F. Healey, Ian W. Smith, David Lillicrap, Pete Lollar
المصدر: Frontiers in Immunology, Vol 11 (2020)
مصطلحات موضوعية: hemophilia A, factor VIII, oxidation, immunogenicity, analytical ultracentrifugation, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Harrison C. Brown, Philip M. Zakas, Stephan N. George, Ernest T. Parker, H. Trent Spencer, Christopher B. Doering
المصدر: Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 57-69 (2018)
وصف الملف: electronic resource
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المؤلفون: Chi Gan, Xi Mo, Christopher B. Doering, Xiaoqin Zhang, Philip M. Zakas, Lanbo Liu, Tao Yue, Renhao Li
المصدر: J Thromb Haemost
مصطلحات موضوعية: Blood Platelets, Protein Folding, CHO Cells, 030204 cardiovascular system & hematology, Platelet membrane glycoprotein, Article, Bernard–Soulier syndrome, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Cricetinae, medicine, Animals, chemistry.chemical_classification, Chinese hamster ovary cell, Bernard-Soulier Syndrome, Platelet Glycoprotein GPIb-IX Complex, Hematology, Transfection, medicine.disease, Cell biology, chemistry, Unfolded protein response, Protein folding, Glycoprotein
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المؤلفون: Anja Brehm, Philip M. Zakas, Caelan E. Radford, Christoph Kannicht, Courtney Dwyer, Christine Brown, Eric A. Gaucher, Barbara Solecka-Witulska, H. Trent Spencer, Kate Nesbitt, Christopher W. Coyle, Christopher B. Doering, Marion Bayer, David Lillicrap
المصدر: Blood Adv
مصطلحات موضوعية: 0301 basic medicine, Hemostasis, Factor VIII, biology, Sequence analysis, In silico, Hematology, Computational biology, 030204 cardiovascular system & hematology, Proteomics, law.invention, Thrombosis and Hemostasis, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Coagulation, Von Willebrand factor, law, Molecular evolution, hemic and lymphatic diseases, von Willebrand Factor, Recombinant DNA, biology.protein, Animals, Gene
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المؤلفون: Pete Lollar, David Lillicrap, John F. Healey, Philip M. Zakas, Ian W. Smith
المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Drug, congenital, hereditary, and neonatal diseases and abnormalities, oxidation, media_common.quotation_subject, animal diseases, Immunology, Excipient, Protein aggregation, immunogenicity, law.invention, 03 medical and health sciences, 0302 clinical medicine, Immune system, law, hemic and lymphatic diseases, medicine, Immunology and Allergy, Humans, media_common, Original Research, Factor VIII, biology, Chemistry, Immunogenicity, Recombinant Proteins, 3. Good health, 030104 developmental biology, Coagulation, Biochemistry, biology.protein, Recombinant DNA, hemophilia A, Antibody, lcsh:RC581-607, Oxidation-Reduction, Ultracentrifugation, analytical ultracentrifugation, 030215 immunology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7578214e1c7636763f1b2cb76e6fbcc6
https://pubmed.ncbi.nlm.nih.gov/32117290 -
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المؤلفون: Philip M. Zakas, Harrison C. Brown, H. Trent Spencer, Stephan N. George, Ernest T. Parker, Christopher B. Doering
المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 57-69 (2018)مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, vector optimization, lcsh:QH426-470, Genetic enhancement, Transgene, Cell, Computational biology, Biology, Genome, Article, promoter design, codon optimization, 03 medical and health sciences, Transcription (biology), hemic and lymphatic diseases, hemophilia, Genetics, medicine, lcsh:QH573-671, Molecular Biology, Gene, Messenger RNA, lcsh:Cytology, AAV, lcsh:Genetics, Vector optimization, 030104 developmental biology, medicine.anatomical_structure, factor VIII, Molecular Medicine
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المؤلفون: Philip M. Zakas, Kristopher A. Knight, Christopher B. Doering, Harrison C. Brown, H. Trent Spencer, Eric A. Gaucher, Shannon L. Meeks
المصدر: Nature biotechnology
مصطلحات موضوعية: 0301 basic medicine, Protein design, Biomedical Engineering, Bioengineering, Biology, Protein Engineering, Applied Microbiology and Biotechnology, Article, Conserved sequence, 03 medical and health sciences, Molecular evolution, Drug Discovery, Conserved Sequence, Genetics, chemistry.chemical_classification, Factor VIII, Sequence Homology, Amino Acid, Drug discovery, Rational design, Proteins, Drug Synergism, Protein engineering, Directed evolution, Amino acid, 030104 developmental biology, chemistry, Molecular Medicine, Biotechnology
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المؤلفون: Wenchun Chen, David S. Paul, Jorge Di Paola, X. Frank Zhang, Wei Deng, Christopher B. Doering, Jerry Ware, Xin Liang, Michael C. Berndt, Philip M. Zakas, Wolfgang Bergmeier, François Lanza, Yan Xu, Renhao Li, Matthew A. Dragovich, Anum K. Syed
المصدر: Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)مصطلحات موضوعية: 0301 basic medicine, Receptor complex, Science, General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Von Willebrand factor, Von Willebrand disease, medicine, Platelet, Platelet activation, Receptor, Multidisciplinary, Mechanosensation, biology, Chemistry, General Chemistry, medicine.disease, 3. Good health, 030104 developmental biology, Biochemistry, biology.protein, Biophysics, Mechanosensitive channels
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المؤلفون: Shannon L. Meeks, Philip M. Zakas, Christopher B. Doering, Kristine Vanijcharoenkarn, Rebecca Markovitz
المصدر: Journal of thrombosis and haemostasis : JTH. 13(1)
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Population, Enzyme-Linked Immunosorbent Assay, Cross Reactions, Hemophilia A, Article, Species Specificity, hemic and lymphatic diseases, Medicine, Animals, Humans, education, Peptide sequence, Blood Coagulation, Autoantibodies, Mice, Knockout, education.field_of_study, Factor VIII, Sheep, biology, business.industry, Coagulants, Immunodominant Epitopes, Cross reactions, Hematology, Virology, Recombinant Proteins, Mice, Inbred C57BL, Disease Models, Animal, Immunology, Acquired hemophilia, biology.protein, Human coagulation factor VIII, Antibody, business, Biomarkers, Epitope Mapping
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المؤلفون: Eric A. Gaucher, Kristopher A. Knight, Ernest T. Parker, H. Trent Spencer, Christopher B. Doering, Philip M. Zakas, Harrison C. Brown
المصدر: Molecular Therapy. 24:S181
مصطلحات موضوعية: Pharmacology, Genetics, congenital, hereditary, and neonatal diseases and abnormalities, In silico, Transgene, Genetic enhancement, Rational design, Computational biology, Transfection, Biology, Directed evolution, Epitope, hemic and lymphatic diseases, Drug Discovery, Molecular Medicine, Molecular Biology, Gene