المؤلفون: Canniff NP; Program in Molecular and Cellular Biology, University of Massachusetts Amherst, USA., Graham JB; Program in Molecular and Cellular Biology, University of Massachusetts Amherst, USA., Guay KP; Program in Molecular and Cellular Biology, University of Massachusetts Amherst, USA., Lubicki DA; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, USA., Eyles SJ; Program in Molecular and Cellular Biology, University of Massachusetts Amherst, USA; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, USA; Institute for Applied Life Sciences, Mass Spectrometry Center, University of Massachusetts Amherst, USA., Rauch JN; Program in Molecular and Cellular Biology, University of Massachusetts Amherst, USA; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, USA., Hebert DN; Program in Molecular and Cellular Biology, University of Massachusetts Amherst, USA; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, USA. Electronic address: dhebert@biochem.umass.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105450. Date of Electronic Publication: 2023 Nov 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum Stress* , Protein Folding*, Humans ; Endoplasmic Reticulum/genetics ; Endoplasmic Reticulum/metabolism ; Glycoproteins/metabolism ; Cell Line

المؤلفون: Lin Y; Biomolecular Science and Engineering, University of California, Santa Barbara, CA, USA., Fichou Y; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA., Rauch JN; Molecular, Cell and Developmental Biology, University of California, Santa Barbara, CA, USA.; Neuroscience Research Institute, University of California, Santa Barbara, CA, USA., Zhang X; Neuroscience Research Institute, University of California, Santa Barbara, CA, USA., Kosik KS; Molecular, Cell and Developmental Biology, University of California, Santa Barbara, CA, USA.; Neuroscience Research Institute, University of California, Santa Barbara, CA, USA., Han S; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA. songihan@ucsb.edu.; Department of Chemical Engineering, University of California, Santa Barbara, CA, USA. songihan@ucsb.edu.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2551, pp. 269-284.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: RNA*/metabolism

المؤلفون: Glasauer SMK; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Goderie SK; Neural Stem Cell Institute, Rensselaer, NY 12144, USA., Rauch JN; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Guzman E; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Audouard M; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Bertucci T; Neural Stem Cell Institute, Rensselaer, NY 12144, USA., Joy S; Neural Stem Cell Institute, Rensselaer, NY 12144, USA., Rommelfanger E; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Luna G; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Keane-Rivera E; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA., Lotz S; Neural Stem Cell Institute, Rensselaer, NY 12144, USA., Borden S; Neural Stem Cell Institute, Rensselaer, NY 12144, USA., Armando AM; Department of Pharmacology, University of California, San Diego, San Diego, CA 92093, USA., Quehenberger O; Department of Pharmacology, University of California, San Diego, San Diego, CA 92093, USA., Temple S; Neural Stem Cell Institute, Rensselaer, NY 12144, USA. Electronic address: sallytemple@neuralsci.org., Kosik KS; Neuroscience Research Institute and Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address: kosik@lifesci.ucsb.edu.

المصدر: Stem cell reports [Stem Cell Reports] 2022 Sep 13; Vol. 17 (9), pp. 2127-2140. Date of Electronic Publication: 2022 Aug 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

مواضيع طبية MeSH: Frontotemporal Dementia*/genetics , tau Proteins*/genetics , tau Proteins*/metabolism, Cholesterol ; Humans ; Mutation/genetics ; Organoids/metabolism

المؤلفون: Carrettiero DC; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.; Center for Natural and Human Sciences, Federal University of ABC, São Bernardo do Campo, SP, Brazil., Almeida MC; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA.; Center for Natural and Human Sciences, Federal University of ABC, São Bernardo do Campo, SP, Brazil., Longhini AP; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Rauch JN; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Han D; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Zhang X; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Najafi S; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA., Gestwicki JE; Institute for Neurodegenerative Disease, Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Kosik KS; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA. kosik@lifesci.ucsb.edu.

المصدر: Nature communications [Nat Commun] 2022 Jun 02; Vol. 13 (1), pp. 3074. Date of Electronic Publication: 2022 Jun 02.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Proteasome Endopeptidase Complex*/metabolism , Ubiquitin*/metabolism, Autophagy ; Humans ; Molecular Chaperones/metabolism ; Proteolysis

المؤلفون: Aralis Z; UC Santa Barbara, Santa Barbara, California., Rauch JN; University of Massachusetts Amherst, Amherst, Massachusetts., Audouard M; UC Santa Barbara, Santa Barbara, California., Valois E; UC Santa Barbara, Santa Barbara, California., Lach RS; UC Santa Barbara, Santa Barbara, California., Solley S; UC Santa Barbara, Santa Barbara, California., Baxter NJ; UC Santa Barbara, Santa Barbara, California., Kosik KS; UC Santa Barbara, Santa Barbara, California., Wilson MZ; UC Santa Barbara, Santa Barbara, California., Acosta-Alvear D; UC Santa Barbara, Santa Barbara, California., Arias C; UC Santa Barbara, Santa Barbara, California.

المصدر: Current protocols [Curr Protoc] 2022 Feb; Vol. 2 (2), pp. e385.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101773894 Publication Model: Print Cited Medium: Internet ISSN: 2691-1299 (Electronic) Linking ISSN: 26911299 NLM ISO Abbreviation: Curr Protoc Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, CRISPR-Cas Systems ; Humans ; Nucleic Acid Amplification Techniques ; Pandemics

المؤلفون: Rauch JN; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA., Valois E; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA., Solley SC; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA., Braig F; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA., Lach RS; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA., Audouard M; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA., Ponce-Rojas JC; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA., Costello MS; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA., Baxter NJ; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA., Kosik KS; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA., Arias C; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA., Acosta-Alvear D; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA daa@lifesci.ucsb.edu mzw@ucsb.edu.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA., Wilson MZ; University of California, Santa Barbara, Department of Molecular, Cellular, and Developmental Biology, Santa Barbara, California, USA daa@lifesci.ucsb.edu mzw@ucsb.edu.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California, USA.; Center for BioEngineering, University of California, Santa Barbara, Santa Barbara, California, USA.

المصدر: Journal of clinical microbiology [J Clin Microbiol] 2021 Mar 19; Vol. 59 (4). Date of Electronic Publication: 2021 Mar 19 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-660X (Electronic) Linking ISSN: 00951137 NLM ISO Abbreviation: J Clin Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19* , SARS-CoV-2*, Humans ; Pandemics ; Point-of-Care Systems ; Polymerase Chain Reaction

المؤلفون: Makley LN; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, CA 94158, United States; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, United States., Johnson OT; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, CA 94158, United States., Ghanakota P; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, United States., Rauch JN; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, CA 94158, United States., Osborn D; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, CA 94158, United States., Wu TS; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, CA 94158, United States., Cierpicki T; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, United States., Carlson HA; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, United States., Gestwicki JE; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California at San Francisco, San Francisco, CA 94158, United States. Electronic address: Jason.gestwicki@ucsf.edu.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Mar 15; Vol. 34, pp. 115990. Date of Electronic Publication: 2021 Jan 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Models, Chemical* , Molecular Dynamics Simulation*, Heat-Shock Proteins/*chemistry , Molecular Chaperones/*chemistry, Binding Sites ; Models, Molecular ; Mutation ; Protein Conformation ; Protein Domains ; Reproducibility of Results

المؤلفون: Rauch JN; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara.; Neuroscience Research Institute, University of California, Santa Barbara., Valois E; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Ponce-Rojas JC; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Aralis Z; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Lach RS; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Zappa F; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Audouard M; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara.; Neuroscience Research Institute, University of California, Santa Barbara., Solley SC; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Vaidya C; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Costello M; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara., Smith H; Student Health Service, University of California, Santa Barbara., Javanbakht A; Student Health Service, University of California, Santa Barbara., Malear B; Student Health Service, University of California, Santa Barbara., Polito L; Student Health Service, University of California, Santa Barbara., Comer S; Department of Pathology, Santa Barbara Cottage Hospital, Santa Barbara, California.; Pacific Diagnostic Laboratories, Santa Barbara, California., Arn K; Department of Medical Education, Division of Infectious Diseases, Santa Barbara Cottage Hospital, Santa Barbara, California., Kosik KS; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara.; Neuroscience Research Institute, University of California, Santa Barbara., Acosta-Alvear D; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara.; Neuroscience Research Institute, University of California, Santa Barbara., Wilson MZ; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara.; Neuroscience Research Institute, University of California, Santa Barbara.; Center for BioEngineering, University of California, Santa Barbara., Fitzgibbons L; Department of Medical Education, Division of Infectious Diseases, Santa Barbara Cottage Hospital, Santa Barbara, California., Arias C; Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara.; Neuroscience Research Institute, University of California, Santa Barbara.; Center for Stem Cell Biology and Engineering, University of California, Santa Barbara.

المصدر: JAMA network open [JAMA Netw Open] 2021 Feb 01; Vol. 4 (2), pp. e2037129. Date of Electronic Publication: 2021 Feb 01.

نوع المنشور: Comparative Study; Evaluation Study; Journal Article

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE

مواضيع طبية MeSH: Clustered Regularly Interspaced Short Palindromic Repeats* , Reverse Transcriptase Polymerase Chain Reaction* , Universities*, COVID-19/*diagnosis , Clinical Laboratory Techniques/*methods , Mass Screening/*methods , SARS-CoV-2/*genetics, Adolescent ; Adult ; COVID-19/virology ; Cohort Studies ; Disease Outbreaks ; Female ; Humans ; Male ; Pandemics ; RNA-Directed DNA Polymerase ; Students ; Viral Load ; Young Adult

المؤلفون: Zhang X; Department of Molecular, Cell and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA., Vigers M; Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA.; Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA., McCarty J; Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA., Rauch JN; Department of Molecular, Cell and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA., Fredrickson GH; Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA., Wilson MZ; Department of Molecular, Cell and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA., Shea JE; Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA.; Department of Physics, University of California, Santa Barbara, Santa Barbara, CA., Han S; Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA.; Department of Chemical Engineering, University of California, Santa Barbara, Santa Barbara, CA., Kosik KS; Department of Molecular, Cell and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA.; Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA.

المصدر: The Journal of cell biology [J Cell Biol] 2020 Nov 02; Vol. 219 (11).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Protein Aggregation, Pathological*, Liquid-Liquid Extraction/*methods , Neuroblastoma/*pathology , Proline/*chemistry , Proline/*metabolism , tau Proteins/*chemistry , tau Proteins/*metabolism, Cell Separation/methods ; Humans ; Microtubules ; Neuroblastoma/metabolism ; Phosphorylation ; Protein Binding ; Tumor Cells, Cultured

المؤلفون: Rauch JN; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Luna G; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Guzman E; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Audouard M; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Challis C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Sibih YE; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Leshuk C; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Hernandez I; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA., Wegmann S; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany., Hyman BT; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Gradinaru V; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Kampmann M; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, The California Institute for Quantitative Biomedical Research, Quantitative Biosciences Institute, University of California, San Francisco, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Kosik KS; Neuroscience Research Institute, Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA, USA. kenneth.kosik@lifesci.ucsb.edu.

المصدر: Nature [Nature] 2020 Apr; Vol. 580 (7803), pp. 381-385. Date of Electronic Publication: 2020 Apr 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Low Density Lipoprotein Receptor-Related Protein-1/*metabolism , tau Proteins/*metabolism, Animals ; Cell Line ; Endocytosis ; Female ; Humans ; Ligands ; Low Density Lipoprotein Receptor-Related Protein-1/genetics ; Male ; Mice ; Neurons/metabolism