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1دورية أكاديمية
المؤلفون: Lin Lin, Fei Hua, Cristian Salinas, Carissa Young, Thierry Bussiere, Joshua F. Apgar, John M. Burke, Kumar Kandadi Muralidharan, Rajasimhan Rajagovindan, Ivan Nestorov
المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 3, Pp 362-372 (2022)
مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2163-8306
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المؤلفون: Catherine K. Xu, Sean R. A. Devenish, Fang Qian, Samuel I. A. Cohen, Oskar Hansson, Thierry Bussiere, Georg Meisl, Sara Linse, Tiernan T. O'Malley, Katja Bernfur, Tuomas P. J. Knowles, Michele Vendruscolo, Eimantas Sileikis, Paul H. Weinreb, Tom Scheidt, Christopher M. Dobson, Martin Lundqvist
المصدر: Nature Structural & Molecular Biology. 27:1125-1133
مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Peptide, 03 medical and health sciences, 0302 clinical medicine, Mechanism of action, Structural Biology, biology.protein, medicine, Biophysics, Structure–activity relationship, Bapineuzumab, Solanezumab, Aducanumab, Antibody, medicine.symptom, Gantenerumab, Molecular Biology, 030217 neurology & neurosurgery, 030304 developmental biology, medicine.drug
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المؤلفون: Edward D. Plowey, Thierry Bussiere, Raj Rajagovindan, Jennifer Sebalusky, Stefan Hamann, Christian von Hehn, Carmen Castrillo-Viguera, Alfred Sandrock, Samantha Budd Haeberlein, Christopher H. van Dyck, Anita Huttner
المصدر: Acta neuropathologica. 144(1)
مصطلحات موضوعية: Aged, 80 and over, Amyloid, Amyloid beta-Peptides, Clinical Trials, Phase I as Topic, Neurofibrillary Tangles, Plaque, Amyloid, Antibodies, Monoclonal, Humanized, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Alzheimer Disease, Positron-Emission Tomography, Humans, Female, Neurology (clinical), Randomized Controlled Trials as Topic
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المؤلفون: Lin Lin, Fei Hua, Cristian Salinas, Carissa Young, Thierry Bussiere, Joshua F. Apgar, John M. Burke, Kumar Kandadi Muralidharan, Rajasimhan Rajagovindan, Ivan Nestorov
المصدر: CPT: pharmacometricssystems pharmacology. 11(3)
مصطلحات موضوعية: Amyloid beta-Peptides, Alzheimer Disease, Modeling and Simulation, Brain, Humans, Pharmacology (medical), Plaque, Amyloid, Network Pharmacology, Antibodies, Monoclonal, Humanized
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المؤلفون: Sara, Linse, Tom, Scheidt, Katja, Bernfur, Michele, Vendruscolo, Christopher M, Dobson, Samuel I A, Cohen, Eimantas, Sileikis, Martin, Lundqvist, Fang, Qian, Tiernan, O'Malley, Thierry, Bussiere, Paul H, Weinreb, Catherine K, Xu, Georg, Meisl, Sean R A, Devenish, Tuomas P J, Knowles, Oskar, Hansson
المصدر: Nature structuralmolecular biology. 27(12)
مصطلحات موضوعية: Models, Molecular, Kinetics, Protein Aggregates, Structure-Activity Relationship, Amyloid beta-Peptides, Neuroprotective Agents, Alzheimer Disease, Protein Conformation, Humans, Antibodies, Monoclonal, Humanized, Models, Biological, Peptide Mapping, Peptide Fragments
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المؤلفون: Paul H. Weinreb, Lary C. Walker, Matthias Staufenbiel, Ruth E. Uhlmann, Rawaa Al-Shaana, Emily M. Ullrich Gavilanes, Søren Christensen, Frank Baumann, Ulrike Obermüller, Stephan A. Kaeser, Fredrik Kartberg, Mathias Jucker, Angelos Skodras, Jay Rasmussen, Holger Cynis, Lan Ye, Anika Buehler, Fang Qian, Carina Bergmann, Juliane Schelle, Sarah K. Fritschi, Thierry Bussiere, Jens-Ulrich Rahfeld, Christine Rother, Natalie Beschorner, Jeffrey B. Stavenhagen
المساهمون: Publica
المصدر: Nat Neurosci
Nature neuroscience 23(12), 1580-1588 (2020). doi:10.1038/s41593-020-00737-wمصطلحات موضوعية: 0301 basic medicine, Male, pharmacology [Tissue Extracts], pharmacokinetics [Antibodies, Monoclonal, Humanized], Plaque, Amyloid, Protein aggregation, pharmacology [Antibodies, Monoclonal, Humanized], neuroscience, pathology [Alzheimer Disease], Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Neurofilament Proteins, antagonists & inhibitors [Amyloid beta-Protein Precursor], Aged, 80 and over, biology, Chemistry, General Neuroscience, aducanumab, Middle Aged, Alzheimer's disease, Cell biology, Aducanumab, Antibody, pharmacology [Antibodies, Blocking], metabolism [Alzheimer Disease], Genetically modified mouse, Amyloid, Immunoprecipitation, Transgene, metabolism [Amyloid beta-Peptides], Mice, Transgenic, Antibodies, Monoclonal, Humanized, Article, 03 medical and health sciences, In vivo, Alzheimer Disease, Animals, Humans, ddc:610, pathology [Plaque, Amyloid], Antibodies, Blocking, Aged, Brain Chemistry, Amyloid beta-Peptides, Tissue Extracts, cerebrospinal fluid [Neurofilament Proteins], Mice, Inbred C57BL, 030104 developmental biology, biology.protein, diseases of the nervous system, Neuroscience, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304ff0cfb27901cbd3f5fac431ae6943
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المؤلفون: Sara Linse, Christopher M. Dobson, Tiernan T. O'Malley, Eimantas Sileikis, Paul H. Weinreb, Tom Scheidt, Katja Bernfur, Michele Vendruscolo, Sean R. A. Devenish, Tuomas P. J. Knowles, Catherine K. Xu, Georg Meisl, Thierry Bussiere, Oskar Hansson, Samuel Cohen, Martin Lundquist, Fang Qian
مصطلحات موضوعية: chemistry.chemical_classification, biology, Chemistry, Aggregation kinetics, Peptide, Computational biology, medicine, biology.protein, Bapineuzumab, Solanezumab, Aducanumab, Amyloid cascade, Antibody, Gantenerumab, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5c7e7c45196a97662812ce573a11e7
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المؤلفون: Anthone W. Dunah, Thierry Bussiere, Kenneth J. Rhodes, Hairuo Peng, Lin Xu, Mahin Arastu, Gnanasambandam Kumaravel, Joy Wang, Melanie S. Brennan, Pamela A. Snodgrass-Belt, Arthur G. Taveras, Mi-young Jung, Tina Talreja, Sowmya Chollate, Zhili Xin, Diana Fahrer, Robert Dunstan, Robert H. Scannevin, Ellen Rohde, H. Moore Arnold
المصدر: Neuropharmacology. 103:57-68
مصطلحات موضوعية: Male, 0301 basic medicine, Gene isoform, Pathology, medicine.medical_specialty, Central nervous system, BACE1-AS, Plaque, Amyloid, Cleavage (embryo), Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Alzheimer Disease, Amyloid precursor protein, medicine, Animals, Protein Isoforms, Pharmacology, Aldehydes, Amyloid beta-Peptides, Dose-Response Relationship, Drug, biology, P3 peptide, Brain, medicine.disease, Rats, Inbred F344, Rats, Disease Models, Animal, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Amyloid Precursor Protein Secretases, Alzheimer's disease, Amyloid precursor protein secretase, 030217 neurology & neurosurgery
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المؤلفون: Sowmya Chollate, Paul H. Weinreb, Fang Qian, Alfred Sandrock, Omar Quintero-Monzon, Thierry Bussiere, Mahin Arastu, Melanie S. Brennan, Mingwei Li, Jan Grimm, Yaming Hang, James Ferrero, Tianle Chen, John O'Gorman, Robert Dunstan, Thomas Engber, Roger M. Nitsch, Marcel Maier, Jeff Sevigny, Ping Chiao, Kenneth J. Rhodes, Alvydas Mikulskis, Yan Ling, Robert H. Scannevin, H. Moore Arnold, Leslie Williams, Christoph Hock, Stephen Salloway
المصدر: Nature
مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, business.industry, Neurotoxicity, medicine.disease, Biochemistry of Alzheimer's disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Crenezumab, Immunology, medicine, Verubecestat, Dementia, Solanezumab, Aducanumab, Gantenerumab, business, 030217 neurology & neurosurgery, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6af16349ff35f219bea2af5a81efc0
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المؤلفون: Thierry Bussiere, Krishna Praneeth Kilambi, Joseph Arndt, Paul H. Weinreb, Fang Qian, Thomas Cameron, Chao Quan, Benjamin A. Smith, R. B. Pepinsky, Martin Bush, Thomas Walz, S. Hamann
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Protein Conformation, lcsh:Medicine, Enzyme-Linked Immunosorbent Assay, Peptide, Antibodies, Monoclonal, Humanized, Article, Epitope, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Alzheimer Disease, Humans, Avidity, Binding site, lcsh:Science, chemistry.chemical_classification, Amyloid beta-Peptides, Multidisciplinary, Linear epitope, lcsh:R, Surface Plasmon Resonance, Receptor–ligand kinetics, Molecular Docking Simulation, Kinetics, 030104 developmental biology, chemistry, Biophysics, lcsh:Q, Binding Sites, Antibody, Immunotherapy, Aducanumab, 030217 neurology & neurosurgery