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1كتاب إلكتروني
المؤلفون: Barbachyn, Michael R., Brickner, Steven J., Gadwood, Robert C., Garmon, Stuart A., Grega, Kevin C., Hutchinson, Douglas K., Munesada, Kiyotaka, Reischer, Robert J., Taniguchi, Mikio, Thomasco, Lisa M., Toops, Dana S., Yamada, Hiromi, Ford, Charles W., Zurenko, Gary E.
المساهمون: Rosen, Barry P., editorAff1, Mobashery, Shahriar, editorAff1
المصدر: Resolving the Antibiotic Paradox : Progress in Understanding Drug Resistance and Development of New Antibiotics. 456:219-238
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المؤلفون: Richard C. Thomas, Matthew J Zaya, Barbachyn Michael R, Wade J. Adams, Betty H. Yagi, Michael A. Wynalda, J P Sams, Larry C. Wienkers, Ford Charles W, J Gregory Slatter, Nancee L. Oien, William Watt, Eric P. Seest, Janice M. Friis, Joel Morris, Judith C. Hamel, Gary E. Zurenko, Lester A. Dolak, Ronda D. Schaadt, Douglas Stapert, Cleek Gary J, Donn G. Wishka, Stuart A. Garmon, Toops Dana S
المصدر: Journal of Medicinal Chemistry. 46:284-302
مصطلحات موضوعية: Male, Staphylococcus aureus, medicine.drug_class, Biological Availability, Carboxamide, Microbial Sensitivity Tests, In Vitro Techniques, Crystallography, X-Ray, Gram-Positive Bacteria, Chemical synthesis, Piperazines, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, In vivo, Drug Resistance, Bacterial, Drug Discovery, Benzene Derivatives, medicine, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Structure–activity relationship, Antibacterial agent, Chemistry, Stereoisomerism, Isoxazoles, Staphylococcal Infections, Combinatorial chemistry, In vitro, Anti-Bacterial Agents, Rats, Biochemistry, Linezolid, Hepatocytes, Molecular Medicine, Antibacterial activity
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المؤلفون: Betty H. Yagi, Suzanne E. Glickman, Susan K. Hendges, Ford Charles W, Toops Dana S, Jonda D. Schaadt, Barbachyn Michael R, Douglas Stapert, Kevin C. Grega, Jerry M. Buysse, Judith C. Hamel, James O. Kilburn, Gary E. Zurenko, William F. Demyan
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:1009-1014
مصطلحات موضوعية: Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, chemistry.chemical_element, Ring (chemistry), Biochemistry, Combinatorial chemistry, In vitro, chemistry.chemical_compound, Meta, chemistry, In vivo, Drug Discovery, Fluorine, Molecular Medicine, Tropone, Antibacterial activity, Molecular Biology
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المؤلفون: Sally P. Klemens, Toops Dana S, James O. Kilburn, Susan K. Hendges, Ford Charles W, S. E. Glickman, Gary E. Zurenko, Kevin C. Grega, Steven J. Brickner, Michael H. Cynamon, Hutchinson Douglas K, Barbachyn Michael R
المصدر: Journal of Medicinal Chemistry. 39:680-685
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, medicine.drug_class, SQ109, Microbial Sensitivity Tests, Pharmacology, Antimycobacterial, Mass Spectrometry, Mycobacterium tuberculosis, chemistry.chemical_compound, In vivo, Acetamides, Drug Discovery, medicine, Eperezolid, Animals, Oxazoles, Antibacterial agent, biology, Chemistry, Isoniazid, Biological activity, biology.organism_classification, Anti-Bacterial Agents, Rats, Molecular Medicine, Mycobacterium avium, medicine.drug
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المؤلفون: Susan K. Hendges, Toops Dana S, Hutchinson Douglas K, Manninen Peter Rudolph, Barbachyn Michael R, Gary E. Zurenko, Stuart A. Garmon, Steven J. Brickner, Ford Charles W, Kevin C. Grega, Debra A. Ulanowicz
المصدر: Journal of Medicinal Chemistry. 39:673-679
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, medicine.drug_class, Antibiotics, Microbial Sensitivity Tests, medicine.disease_cause, Mass Spectrometry, Microbiology, Mice, chemistry.chemical_compound, Dogs, Antibiotic resistance, Anti-Infective Agents, Acetamides, Drug Discovery, medicine, Eperezolid, Animals, Oxazoles, Oxazolidinones, Antibacterial agent, Linezolid, Drug Resistance, Microbial, Combinatorial chemistry, Drug Resistance, Multiple, Rats, Multiple drug resistance, chemistry, Staphylococcus aureus, Molecular Medicine, Vancomycin, Female, Antibacterial activity, medicine.drug
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المؤلفون: Toops Dana S, Barbachyn Michael R
المصدر: The Journal of Organic Chemistry. 58:6505-6508
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Bicyclic molecule, Organic Chemistry, Organic chemistry, Pentanes
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المؤلفون: Raymond J. Reid, Gary E. Zurenko, Ronda D. Schaadt, Barbachyn Michael R, John W. Allison, Toops Dana S, Hutchinson Douglas K, Betty H. Yagi
المصدر: Bioorganic & Medicinal Chemistry Letters. 3:671-676
مصطلحات موضوعية: Bicyclic molecule, Chemistry, medicine.drug_class, Stereochemistry, Aerobic bacteria, Protein subunit, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, A protein, Quinolone, medicine.disease_cause, Biochemistry, Ciprofloxacin, Staphylococcus aureus, Drug Discovery, medicine, Molecular Medicine, Molecular Biology, medicine.drug, Antibacterial agent
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المؤلفون: Ronda D. Schaadt, Betty H. Yagi, R. J. Reid, J. W. Allison, Gary E. Zurenko, Toops Dana S, Barbachyn Michael R, Hutchinson Douglas K
المصدر: ChemInform. 26
مصطلحات موضوعية: Bicyclic molecule, medicine.drug_class, Stereochemistry, Chemistry, Protein subunit, medicine, General Medicine, Quinolone, Antibacterial agent
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المؤلفون: Betty H. Yagi, Kevin C. Grega, Ronda D. Schaadt, W. F. Demyan, Toops Dana S, Gary E. Zurenko, Steven J. Brickner, J. O. Kilburn, Barbachyn Michael R, Debra A. Ulanowicz, Ford Charles W, S. E. Glickman, Judith C. Hamel, J. M. Buysse, Douglas Stapert
المصدر: ChemInform. 27
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Substitution (logic), Identification (biology), General Medicine, Tropone, Antibacterial activity, Combinatorial chemistry
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المؤلفون: Susan K. Hendges, Kevin C. Grega, Hutchinson Douglas K, Gary E. Zurenko, Manninen Peter Rudolph, Toops Dana S, Stuart A. Garmon, Ford Charles W, Steven J. Brickner, Debra A. Ulanowicz, Barbachyn Michael R
المصدر: ChemInform. 27
مصطلحات موضوعية: biology, Chemistry, medicine.drug_class, Antibiotics, General Medicine, biology.organism_classification, Microbiology, Multiple drug resistance, Mycobacterium tuberculosis, Antibiotic resistance, Mechanism of action, In vivo, medicine, Vancomycin, medicine.symptom, Antibacterial activity, medicine.drug