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1Lead optimization for 3-acylaminoindazole for Adapter Associated Kinase 1 and BMP-2 inducible kinase
المؤلفون: Ghosh, Swarnendu
المساهمون: Lääketieteen laitos, School of Medicine, Terveystieteiden tiedekunta, Lääketieteen laitos, Biolääketiede, Faculty of Health Sciences, School of Medicine, Biomedicine, Terveystieteiden tiedekunta, Faculty of Health Sciences
مصطلحات موضوعية: kinaasit, entsyymit, drug design, enzymer, enzymes, biomedicine, läkemedelsdesign, proteins, lääkesuunnittelu, lääkkeet, kinases, kinaser, proteiner, läkemedel, biolääketiede, proteiinit, medicines
وصف الملف: fulltext; Julkaisun kokoteksti; Fulltext of publication
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3891::2cba0141d5b1c95617c7f329c7d202f2
http://urn.fi/urn:nbn:fi:uef-20220718 -
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المؤلفون: Weixiao Yuan Wahlgren, Elin Claesson, Iida Tuure, Sergio Trillo-Muyo, Szabolcs Bódizs, Janne A. Ihalainen, Heikki Takala, Sebastian Westenhoff
المساهمون: Medicum, Department of Anatomy
مصطلحات موضوعية: Models, Molecular, kinaasit, Multidisciplinary, photochemistry, Histidine Kinase, Light, Bacteria, electron microscopy, Biochemistry and Molecular Biology, General Physics and Astronomy, elektronimikroskopia, General Chemistry, General Biochemistry, Genetics and Molecular Biology, kinases, Bacterial Proteins, plant signalling, 3111 Biomedicine, Phytochrome, valokemia, Biokemi och molekylärbiologi, Signal Transduction
وصف الملف: application/pdf; fulltext
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12af9ca41c41f29a5b0903cf3175d0f
http://urn.fi/URN:NBN:fi:jyu-202212225800 -
3Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage
المؤلفون: Kristina Hopfensperger, Kalle Saksela, Kei Sato, Daniel Sauter, Rishikesh Lotke, Zhe Zhao, Perttu Permi, Helena Tossavainen, Riku Fagerlund, Smitha Srinivasachar Badarinarayan, Frank Kirchhoff
المساهمون: Department of Virology, HUSLAB, Kalle Saksela / Principal Investigator, Infection Biology Research Program
المصدر: PLoS Pathogens, Vol 17, Iss 11, p e1009728 (2021)
PLoS Pathogensمصطلحات موضوعية: RNA viruses, virukset, viruses, Simian Acquired Immunodeficiency Syndrome, HIV Infections, Pathology and Laboratory Medicine, SH3 domain, White Blood Cells, Immunodeficiency Viruses, Animal Cells, Medicine and Health Sciences, Biology (General), Mammals, Genetics, 11832 Microbiology and virology, 0303 health sciences, Kinase, 030302 biochemistry & molecular biology, Eukaryota, virus diseases, Transfection, 3. Good health, SIV, Medical Microbiology, Viral Pathogens, Viral evolution, Viruses, Vertebrates, Proto-Oncogene Proteins c-hck, Apes, Simian Immunodeficiency Virus, Pathogens, Cellular Types, Tyrosine kinase, Research Article, Primates, kinaasit, Evolutionary Immunology, Lineage (genetic), QH301-705.5, Immune Cells, Immunology, evoluutio, Biology, Research and Analysis Methods, HIV-tartunta, Microbiology, Viral Evolution, Evolution, Molecular, src Homology Domains, 03 medical and health sciences, Virology, Retroviruses, Animals, Humans, Luciferase, Amino Acid Sequence, nef Gene Products, Human Immunodeficiency Virus, Chimpanzees, Molecular Biology Techniques, Microbial Pathogens, Molecular Biology, 030304 developmental biology, Evolutionary Biology, Blood Cells, Sequence Homology, Amino Acid, Macrophages, Lentivirus, Organisms, Biology and Life Sciences, HIV, Cell Biology, RC581-607, Organismal Evolution, 3121 General medicine, internal medicine and other clinical medicine, Microbial Evolution, Amniotes, HIV-1, Parasitology, Salt bridge, proteiinit, Immunologic diseases. Allergy, Zoology
وصف الملف: application/pdf; fulltext
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565fd13bb0bcf44198b041bbb8f3bb4a
http://hdl.handle.net/10138/341050 -
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مصطلحات موضوعية: soluviestintä, kinaasit, entsyymit, integriinit, Nuclear Magnetic Resonance (NMR), integrin, ITAM, immunokemia, ta1182, tyrosiini, NMR-spektroskopia, Syk kinase, perna
URL الوصول: https://explore.openaire.eu/search/publication?articleId=CSC_________::38f8cb67a60f75ac983dc445f9fd5aa9
http://juuli.fi/Record/0339607719 -
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المؤلفون: Berntsson, Oskar, Diensthuber, Ralph P., Panman, Matthijs R., Björling, Alexander, Gustavsson, Emil, Hoernke, Maria, Hughes, Ashley J., Henry, Léocadie, Niebling, Stephan, Takala, Heikki, Ihalainen, Janne A., Newby, Gemma, Kerruth, Silke, Heberle, Joachim, Liebi, Marianne, Menzel, Andreas, Henning, Robert, Kosheleva, Irina, Möglich, Andreas, Westenhoff, Sebastian
المصدر: 'Nature Communications ', vol: 8, pages: 284-1-284-8 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communicationsمصطلحات موضوعية: Models, Molecular, kinaasit, entsyymit, Histidine Kinase, Light, Protein Conformation, Science, Crystallography, X-Ray, Article, Protein Structure, Secondary, aktivointi, Bacterial Proteins, Protein Domains, X-Ray Diffraction, photoactivation, Scattering, Small Angle, Nanotechnology, sensor histidine kinases
وصف الملف: application/pdf