المؤلفون: Székvölgyi L; MTA-DE Momentum, Genome Architecture and Recombination Research Group, Department of Molecular and Nanopharmaceutics, Faculty of Pharmacy, University of Debrecen, Debrecen, 4032, Hungary. lorantsz@med.unideb.hu.

المصدر: Biologia futura [Biol Futur] 2024 Jun; Vol. 75 (2), pp. 177-182. Date of Electronic Publication: 2024 Mar 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101738236 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2676-8607 (Electronic) Linking ISSN: 26768607 NLM ISO Abbreviation: Biol Futur Subsets: MEDLINE

مواضيع طبية MeSH: R-Loop Structures*, Humans ; Genomic Instability/genetics ; Animals

المؤلفون: Jose L; Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Smith K; Indiana University Simon Comprehensive Cancer Center American Cancer Society Post-Baccalaureate Diversity in Cancer Research Education Program, Indiana University School of Medicine, Indianapolis, Indiana, USA., Crowner A; Indiana University Simon Comprehensive Cancer Center American Cancer Society Post-Baccalaureate Diversity in Cancer Research Education Program, Indiana University School of Medicine, Indianapolis, Indiana, USA., Androphy EJ; Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA., DeSmet M; Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

المصدر: Journal of virology [J Virol] 2024 Aug 20; Vol. 98 (8), pp. e0100324. Date of Electronic Publication: 2024 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

مواضيع طبية MeSH: RNA Helicases*/genetics , RNA Helicases*/metabolism , Multifunctional Enzymes*/genetics , Multifunctional Enzymes*/metabolism , DNA Helicases*/metabolism , DNA Helicases*/genetics , R-Loop Structures*/genetics , Promoter Regions, Genetic*, Humans ; Plasmids/genetics ; Virus Replication ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Papillomaviridae/genetics ; Genome, Viral ; Oncogene Proteins, Viral/genetics ; Oncogene Proteins, Viral/metabolism ; Transcription, Genetic ; Cell Line ; DNA, Viral/genetics

المؤلفون: Chiang HC; Department of Biochemistry and Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC 20037., Qi L; Department of Anatomy and Cell Biology, School of Medicine & Health Sciences, The George Washington University, Washington, DC 20037., Mitra P; Department of Biochemistry and Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC 20037., Huang Y; Department of Biochemistry and Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC 20037., Hu Y; Department of Anatomy and Cell Biology, School of Medicine & Health Sciences, The George Washington University, Washington, DC 20037., Li R; Department of Biochemistry and Molecular Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC 20037.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Aug 13; Vol. 121 (33), pp. e2403600121. Date of Electronic Publication: 2024 Aug 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: BRCA1 Protein*/metabolism , BRCA1 Protein*/genetics , Carcinogenesis*/genetics , R-Loop Structures*, Animals ; Mice ; Female ; Mammary Neoplasms, Animal/genetics ; Mammary Neoplasms, Animal/metabolism ; Mammary Neoplasms, Animal/pathology ; Estrogen Receptor alpha/metabolism ; Estrogen Receptor alpha/genetics ; Genomic Instability ; DNA Replication ; Humans ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Breast Neoplasms/metabolism

المؤلفون: Zannini L; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', CNR, Pavia, 27100, Italy., Cardano M; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', CNR, Pavia, 27100, Italy., Liberi G; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', CNR, Pavia, 27100, Italy. giordano.liberi@igm.cnr.it., Buscemi G; Istituto di Genetica Molecolare 'Luigi Luca Cavalli-Sforza', CNR, Pavia, 27100, Italy. giacomo.buscemi@igm.cnr.it.

المصدر: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Aug 09; Vol. 81 (1), pp. 339. Date of Electronic Publication: 2024 Aug 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

مواضيع طبية MeSH: Autophagy*/genetics , DNA Damage* , DNA Helicases*/metabolism , DNA Helicases*/genetics , DNA Helicases*/deficiency , Inflammation*/pathology , Inflammation*/metabolism , Inflammation*/genetics , Multifunctional Enzymes*/metabolism , Multifunctional Enzymes*/genetics , Nucleotidyltransferases*/metabolism , Nucleotidyltransferases*/genetics , R-Loop Structures* , RNA Helicases*/metabolism , RNA Helicases*/genetics, Humans ; BRCA1 Protein/metabolism ; BRCA1 Protein/genetics ; BRCA1 Protein/deficiency ; DNA Repair Enzymes/metabolism ; DNA Repair Enzymes/genetics ; DNA Repair Enzymes/deficiency ; Exodeoxyribonucleases/metabolism ; Exodeoxyribonucleases/genetics ; Immunity, Innate ; Phosphoproteins

المؤلفون: Choi SY; Department of Biology, Jeju National University, Jeju, the Republic of Korea. Electronic address: sychoi@jejunu.ac.kr.

المصدر: DNA repair [DNA Repair (Amst)] 2024 Aug; Vol. 140, pp. 103697. Date of Electronic Publication: 2024 May 29.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139138 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-7856 (Electronic) Linking ISSN: 15687856 NLM ISO Abbreviation: DNA Repair (Amst) Subsets: MEDLINE

مواضيع طبية MeSH: DNA Damage* , DNA Repair* , R-Loop Structures*, Humans ; Animals ; Genomic Instability ; DNA/metabolism

المؤلفون: Luna R; Andalusian Center of Molecular Biology and Regenerative Medicine (CABIMER), Universidad de Sevilla-Spanish National Research Council (CSIC), 41092 Seville, Spain.; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain., Gómez-González B; Andalusian Center of Molecular Biology and Regenerative Medicine (CABIMER), Universidad de Sevilla-Spanish National Research Council (CSIC), 41092 Seville, Spain.; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain., Aguilera A; Andalusian Center of Molecular Biology and Regenerative Medicine (CABIMER), Universidad de Sevilla-Spanish National Research Council (CSIC), 41092 Seville, Spain; aguilo@us.es.; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain.

المصدر: Genes & development [Genes Dev] 2024 Jul 19; Vol. 38 (11-12), pp. 504-527. Date of Electronic Publication: 2024 Jul 19.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

مواضيع طبية MeSH: Genomic Instability*/genetics , R-Loop Structures* , RNA*/metabolism , RNA*/genetics, DNA Replication/genetics ; Animals ; Humans ; Transcription, Genetic/genetics

المؤلفون: Kassab MA; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA. muzaffer.kassab@pennmedicine.upenn.edu.; Present address: Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. muzaffer.kassab@pennmedicine.upenn.edu., Chen Y; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.; Present address: Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA., Wang X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.; Present address: Westlake University, Hangzhou, Zhejiang, P. R. China., He B; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA.; Present address: Division of Cellular and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, CA, 94705, USA., Brown EJ; Present address: Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Yu X; Department of Cancer Genetics and Epigenetics, Beckman Research Institute, City of Hope Medical Center, Duarte, CA, 91010, USA. yuxiaochun@westlake.edu.cn.; Present address: Westlake University, Hangzhou, Zhejiang, P. R. China. yuxiaochun@westlake.edu.cn.

المصدر: BMC biology [BMC Biol] 2024 Jul 08; Vol. 22 (1), pp. 151. Date of Electronic Publication: 2024 Jul 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE

مواضيع طبية MeSH: Immunoglobulin Class Switching*/genetics , Cytidine Deaminase*/metabolism , Cytidine Deaminase*/genetics , Cytidine Deaminase*/chemistry , R-Loop Structures*, Animals ; Mice ; Methylation ; Immunoglobulin Heavy Chains/genetics ; Immunoglobulin Heavy Chains/metabolism ; Recombination, Genetic ; RNA/metabolism ; RNA/genetics

المؤلفون: Wang C; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China.; Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510275, China., Huang Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Yang Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China.; Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China., Li R; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Li Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Qiu H; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Wu J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Shi G; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Ma W; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China., Songyang Z; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol and Guangzhou Key Laboratory of Healthy Aging, School of Lifesciences, Sun Yat-sen University, Guangzhou 510275, China.; Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510275, China.

المصدر: Protein & cell [Protein Cell] 2024 Jul 01; Vol. 15 (7), pp. 493-511.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 101532368 Publication Model: Print Cited Medium: Internet ISSN: 1674-8018 (Electronic) Linking ISSN: 1674800X NLM ISO Abbreviation: Protein Cell Subsets: MEDLINE

مواضيع طبية MeSH: Telomere*/metabolism , Telomere*/genetics , Nuclear Factor 90 Proteins*/metabolism , Nuclear Factor 90 Proteins*/genetics , Homologous Recombination* , R-Loop Structures*/genetics, Humans ; DEAD-box RNA Helicases/metabolism ; DEAD-box RNA Helicases/genetics ; HEK293 Cells ; Telomere Homeostasis

المؤلفون: Wen C; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Cao L; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Wang S; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Xu W; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Yu Y; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Zhao S; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China., Yang F; Advanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, 250012, China., Chen ZJ; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China.; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China.; Department of Reproductive Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao S; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China. shidouzhao@sdu.edu.cn., Yang Y; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China. YangYJ0204@sdu.edu.cn., Qin Y; State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Shandong Key Laboratory of Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.; Research Unit of Gametogenesis and Health of ART-Offspring, Chinese Academy of Medical Sciences (No.2021RU001), Jinan, Shandong, 250012, China. qinyingying@sdu.edu.cn.

المصدر: The EMBO journal [EMBO J] 2024 Jul; Vol. 43 (14), pp. 3044-3071. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

مواضيع طبية MeSH: DEAD-box RNA Helicases*/metabolism , DEAD-box RNA Helicases*/genetics , Genomic Instability* , Minichromosome Maintenance Proteins*/metabolism , Minichromosome Maintenance Proteins*/genetics , R-Loop Structures*/genetics, Animals ; Female ; Humans ; Male ; Mice ; DNA Damage ; Germ Cells/metabolism

المؤلفون: Ng RR; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Lin Z; Department of Biology, Shantou University, Shantou, Guangdong, China., Zhang Y; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Ti SC; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Javed A; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Wong JWH; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Fang Q; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Leung JWC; Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Tang AHN; Department of Pathology, School of Clinical Medicine LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R., Huen MSY; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong S.A.R.; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Pokfulam, Hong Kong S.A.R.

المصدر: Science advances [Sci Adv] 2024 Jul 19; Vol. 10 (29), pp. eadm9577. Date of Electronic Publication: 2024 Jul 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Androgens*/metabolism , Receptors, Androgen*/metabolism , Receptors, Androgen*/genetics , R-Loop Structures* , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/metabolism , Prostatic Neoplasms*/pathology , RNA Polymerase II*/metabolism , RNA Polymerase II*/genetics, Humans ; Male ; Cell Line, Tumor ; DNA Topoisomerases, Type II/metabolism ; DNA Topoisomerases, Type II/genetics ; Transcription, Genetic ; DNA Breaks, Double-Stranded ; Transcription Initiation Site ; Gene Expression Regulation, Neoplastic ; Protein Binding ; Transcriptional Activation