المؤلفون: Zhan J; Key Laboratory of Ecological Restoration and Conservation of Coastal Wetlands in Universities of Shandong, The Institute for Advanced Study of Coastal Ecology, Ludong University, Yantai 264025, PR China., Song C; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS); Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China., Wang Z; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS); Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China; School of Ocean, Yantai University, Yantai 264005, PR China., Wu H; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS); Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China., Ji C; CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS); Shandong Key Laboratory of Coastal Environmental Processes, YICCAS, Yantai 264003, PR China. Electronic address: clji@yic.ac.cn.

المصدر: The Science of the total environment [Sci Total Environ] 2024 Jun 25; Vol. 931, pp. 172919. Date of Electronic Publication: 2024 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1026 (Electronic) Linking ISSN: 00489697 NLM ISO Abbreviation: Sci Total Environ Subsets: MEDLINE

مواضيع طبية MeSH: Cadmium*/toxicity , Salinity* , Water Pollutants, Chemical*/toxicity , Transcriptome*/drug effects , Dose-Response Relationship, Drug*, Animals

المؤلفون: Wang Z; Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, 130033, PR China., Guo X; Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, 130033, PR China., Zhao H; Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Changchun, 130033, PR China. zhaohf@jlu.edu.cn.

المصدر: BMC cancer [BMC Cancer] 2024 Jun 08; Vol. 24 (1), pp. 707. Date of Electronic Publication: 2024 Jun 08.

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Vaginal Neoplasms*/radiotherapy , Vaginal Neoplasms*/pathology , Dose-Response Relationship, Radiation* , Radiotherapy Dosage*, Humans ; Female ; Neoplasm Recurrence, Local/radiotherapy ; Middle Aged ; Treatment Outcome ; Aged ; Vagina/radiation effects ; Vagina/pathology

المؤلفون: Hebert K; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France., Santoro L; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France.; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France., Monnier M; Biometry Unit, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France., Castan F; Biometry Unit, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France., Berkane I; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France., Assénat E; Department of Medical Oncology, CHU de Montpellier, Université de Montpellier, Montpellier, France., Fersing C; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France.; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France.; Biometry Unit, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France.; Department of Medical Oncology, CHU de Montpellier, Université de Montpellier, Montpellier, France.; IBMM, Université de Montpellier, CNRS, ENSCM, Montpellier, France; and., Gélibert P; Centre Hospitalier Métropole Savoie, Chambéry, France., Pouget JP; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France., Bardiès M; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France.; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France., Kotzki PO; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France.; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France., Deshayes E; Department of Nuclear Medicine, Institut du Cancer de Montpellier, Université de Montpellier, Montpellier, France; emmanuel.deshayes@icm.unicancer.fr.; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France.

المصدر: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2024 Jun 03; Vol. 65 (6), pp. 923-930. Date of Electronic Publication: 2024 Jun 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

مواضيع طبية MeSH: Neuroendocrine Tumors*/radiotherapy , Neuroendocrine Tumors*/diagnostic imaging , Neuroendocrine Tumors*/pathology , Octreotide*/analogs & derivatives , Octreotide*/therapeutic use , Pancreatic Neoplasms*/radiotherapy , Pancreatic Neoplasms*/diagnostic imaging , Organometallic Compounds*/therapeutic use , Stomach Neoplasms*/radiotherapy , Stomach Neoplasms*/diagnostic imaging , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/pathology , Intestinal Neoplasms*/radiotherapy , Intestinal Neoplasms*/diagnostic imaging , Intestinal Neoplasms*/pathology , Precision Medicine* , Radiometry* , Dose-Response Relationship, Radiation*, Humans ; Male ; Female ; Middle Aged ; Aged ; Adult ; Aged, 80 and over ; Treatment Outcome ; Retrospective Studies

SCR Disease Name: Gastro-enteropancreatic neuroendocrine tumor

المؤلفون: Ghorbanzadeh B; Department of Pharmacology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran. Electronic address: b_ghorbanzadeh82@yahoo.com., Azizolahi B; Department of Laboratory Sciences, School of Allied Medical Sciences, Dezful University of Medical Sciences, Dezful, Iran., Masoudipur F; Department of Pharmacology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran., Boroun A; Department of Pharmacology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran., Azizi M; Department of Pharmacology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran., Oroojan AA; Department of Physiology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran., Jafrasteh S; Clinical Research Development Unit, Ganjavian Hospital, Dezful University of Medical Sciences, Dezful, Iran.

المصدر: Behavioural brain research [Behav Brain Res] 2024 Jul 09; Vol. 469, pp. 115065. Date of Electronic Publication: 2024 May 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

مواضيع طبية MeSH: Acetaminophen*/pharmacology , Acetaminophen*/administration & dosage , Antidepressive Agents*/pharmacology , Antidepressive Agents*/administration & dosage , Naloxone*/pharmacology , Narcotic Antagonists*/pharmacology , Narcotic Antagonists*/administration & dosage , Dose-Response Relationship, Drug*, Animals ; Male ; Mice ; Swimming ; Depression/drug therapy ; Depression/metabolism ; Morphine/pharmacology ; Morphine/administration & dosage ; Hippocampus/drug effects ; Hippocampus/metabolism ; Disease Models, Animal ; Analgesics, Opioid/pharmacology ; Analgesics, Opioid/administration & dosage ; Analgesics, Non-Narcotic/pharmacology ; Analgesics, Non-Narcotic/administration & dosage ; Receptors, Opioid/metabolism ; Receptors, Opioid/drug effects ; Receptors, Opioid, mu/metabolism ; Receptors, Opioid, mu/drug effects

المؤلفون: Karadenizli Taşkin S; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: skaradenizli@kocaeli.edu.tr., Şahin D; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: sahindeniztr@yahoo.com., Dede F; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: fzltdd.08@gmail.com., Ünal Halbutoğullari ZS; Stem Cell and Gene Therapy Research and Application Center, Kocaeli University, Kocaeli, Turkey. Electronic address: zehraseda@gmail.com., Sarihan M; Department of Medical Biology/Proteomics Laboratory, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: mbgsarihan@hotmail.com., Kurnaz Özbek S; Department of Histology and Embryology, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: semakurnaz85@gmail.com., Özsoy ÖD; Department of Biochemistry, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: doga83@hotmail.com., Kasap M; Department of Medical Biology/Proteomics Laboratory, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: mkasap2008@gmail.com., Yazir Y; Stem Cell and Gene Therapy Research and Application Center, Kocaeli University, Kocaeli, Turkey; Department of Histology and Embryology, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: yusufhanyazir@yahoo.com., Ateş N; Physiology Department, Kocaeli University Medical Faculty, Kocaeli, Turkey. Electronic address: nates@kocaeli.edu.tr.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2024 Jul 05; Vol. 974, pp. 176613. Date of Electronic Publication: 2024 Apr 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Thapsigargin*/pharmacology , Endoplasmic Reticulum Stress*/drug effects , Unfolded Protein Response*/drug effects , Dose-Response Relationship, Drug*, Animals ; Rats ; Male ; NF-kappa B/metabolism ; Immunity/drug effects ; Electroencephalography ; eIF-2 Kinase/metabolism ; eIF-2 Kinase/genetics

المؤلفون: Wang Z; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China., Zhang J; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China., Xia T; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China., He R; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China., Yan F; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, P.R. China.

المصدر: Journal of biopharmaceutical statistics [J Biopharm Stat] 2024 Jul 03; Vol. 34 (4), pp. 582-595. Date of Electronic Publication: 2023 Jul 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9200436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5711 (Electronic) Linking ISSN: 10543406 NLM ISO Abbreviation: J Biopharm Stat Subsets: MEDLINE

مواضيع طبية MeSH: Bayes Theorem* , Clinical Trials, Phase I as Topic*/statistics & numerical data , Clinical Trials, Phase I as Topic*/methods , Clinical Trials, Phase II as Topic*/statistics & numerical data , Clinical Trials, Phase II as Topic*/methods , Dose-Response Relationship, Drug* , Research Design*/statistics & numerical data , Computer Simulation*, Humans ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Logistic Models ; Neoplasms/drug therapy ; Linear Models ; Models, Statistical

المؤلفون: Coli KG; 1 Upstate University Hospital, Pharmacy Department, Syracuse, New York., Yuksel JM; 2 Upstate Community Hospital, Pharmacy Department, Syracuse, New York., McCall KL; 3 Binghamton University School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacy Practice, Johnson City, New York., Guan J; 2 Upstate Community Hospital, Pharmacy Department, Syracuse, New York., Ulen KR; 2 Upstate Community Hospital, Pharmacy Department, Syracuse, New York., Noviasky J; 2 Upstate Community Hospital, Pharmacy Department, Syracuse, New York.

المصدر: The Senior care pharmacist [Sr Care Pharm] 2024 Jul 01; Vol. 39 (7), pp. 249-258.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Consultant Pharmacists Country of Publication: United States NLM ID: 101737969 Publication Model: Print Cited Medium: Print ISSN: 2639-9636 (Print) Linking ISSN: 26399636 NLM ISO Abbreviation: Sr Care Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Length of Stay* , Patient Readmission*/statistics & numerical data , Amitriptyline*/administration & dosage , Amitriptyline*/analogs & derivatives , Amitriptyline*/adverse effects , Dose-Response Relationship, Drug*, Humans ; Aged ; Retrospective Studies ; Male ; Female ; Aged, 80 and over ; Inpatients ; Cholinergic Antagonists/administration & dosage ; Cholinergic Antagonists/adverse effects ; Cohort Studies ; Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/adverse effects

المؤلفون: Chang HP; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, New York, USA., Cheung YK; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, New York, USA., Liu S; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, New York, USA., Shah DK; Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, New York, USA.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Jul; Vol. 90 (7), pp. 1637-1655. Date of Electronic Publication: 2024 Apr 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Dose-Response Relationship, Drug* , Immunoconjugates*/pharmacokinetics , Immunoconjugates*/administration & dosage , Models, Biological* , Oligopeptides*/pharmacokinetics , Oligopeptides*/administration & dosage, Humans ; Area Under Curve

المؤلفون: Lange S; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, ON M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada. Electronic address: shannon.lange@camh.ca., Llamosas-Falcón L; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada; Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada., Kim KV; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada., Lasserre AM; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada; Addiction Medicine, Department of Psychiatry, Lausanne University Hospital, rue du Bugnon 23, Lausanne 1011, Switzerland., Orpana H; Public Health Agency of Canada, 785 Carling Ave., Ottawa, ON K1A 0K9, Canada; School of Psychology, University of Ottawa, 136 Jean-Jacques Lussier, Ottawa, ON K1N 6N5, Canada., Bagge CL; Department of Psychiatry, University of Michigan Medical School, 1500 E Medical Center Dr, Ann Arbor, MI 48109, United States; Center for Clinical Management Research, Department of Veterans Affairs, 2215 Fuller Rd, Ann Arbor, MI 48105, United States., Roerecke M; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON M5T 1R8, Canada; Dalla Lana School of Public Health, University of Toronto, 155 College St., Toronto, ON M5T 3M7, Canada., Rehm J; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, ON M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada; Dalla Lana School of Public Health, University of Toronto, 155 College St., Toronto, ON M5T 3M7, Canada; Program on Substance Abuse & WHO European Region Collaboration Centre, Public Health Agency of Catalonia, Roc Boronat Street 81-95, Barcelona, Catalonia 08005, Spain; Zentrum für Interdisziplinäre Suchtforschung (ZIS), Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, Hamburg 20246, Germany., Probst C; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, 33 Ursula Franklin St., Toronto, ON M5S 2S1, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, ON M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

المصدر: Drug and alcohol dependence [Drug Alcohol Depend] 2024 Jul 01; Vol. 260, pp. 111348. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article; Meta-Analysis; Systematic Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 7513587 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0046 (Electronic) Linking ISSN: 03768716 NLM ISO Abbreviation: Drug Alcohol Depend Subsets: MEDLINE

مواضيع طبية MeSH: Alcohol Drinking*/epidemiology , Alcohol Drinking*/psychology , Suicide*/statistics & numerical data , Dose-Response Relationship, Drug*, Humans ; Male ; Female ; Sex Factors

المؤلفون: Yang J; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China., Liu B; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China., Yan W; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China., Zhao X; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China., Wang C; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China., Zhu Q; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China., Zou Y; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. Electronic address: zouyi@cpu.edu.cn., Xu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. Electronic address: xyg@cpu.edu.cn., Gu H; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China; Jiangsu Key Laboratory of Drug Design and Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. Electronic address: guhongfengabc@163.com.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Jul; Vol. 148, pp. 107469. Date of Electronic Publication: 2024 May 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Poly(ADP-ribose) Polymerase Inhibitors*/chemistry , Poly(ADP-ribose) Polymerase Inhibitors*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Drug Screening Assays, Antitumor* , Immunotherapy* , Drug Discovery* , Dose-Response Relationship, Drug* , Cell Proliferation*/drug effects, Humans ; Structure-Activity Relationship ; Molecular Structure ; Animals ; Mice ; Poly(ADP-ribose) Polymerases/metabolism ; Cell Line, Tumor ; Neoplasms/drug therapy ; Neoplasms/pathology ; Mice, Inbred BALB C