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المؤلفون: Zhuang, Y., Noviello, C. M., Hibbs, R. E., Howard, R. J., Lindahl, Erik, 1972
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(43)
مصطلحات موضوعية: cholesterol, coarse-grained simulations, computational electrophysiology, ligand-gated ion channel, nicotinic acetylcholine receptor, Allosteric Regulation, alpha7 Nicotinic Acetylcholine Receptor, Humans, Isoxazoles, Ligand-Gated Ion Channels, Ligands, Lipids, Phenylurea Compounds, Receptors, Nicotinic, 1 (5 chloro 2, 4 dimethoxyphenyl) 3 (5 methyl 3 isoxazolyl)urea, bungarotoxin receptor, calcium ion, ligand gated ion channel, 1-(5-chloro-2, 4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea, carbanilamide derivative, isoxazole derivative, ligand, lipid, nicotinic receptor, allosterism, Article, binding affinity, electrophysiology, human, ion transport, ligand binding, lipophilicity, mathematical computing, membrane potential, molecular dynamics, molecular interaction, phase transition, protein structure, receptor down regulation, structure analysis, metabolism
وصف الملف: print
URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-328810
https://doi.org/10.1073/pnas.2208081119 -
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المؤلفون: Przemyslaw Grudnik, Lukasz Skalniak, Bogdan Musielak, Katarzyna Magiera, Grzegorz Dubin, Tad A. Holak, Krzysztof M. Zak, Ricarda Törner, Alexander Dömling, Katarzyna Guzik
المساهمون: Drug Design, Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Journal of Medicinal Chemistry, 60(13), 5857-5867. AMER CHEMICAL SOC
مصطلحات موضوعية: 0301 basic medicine, 4 benzodioxin 6 yl) 2 methylphenyl]methanol, crystallization, medicine.medical_treatment, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 hydroxy 5 methylbenzaldehyde, 2,6 dimethoxy 4 [(2 methyl 3 phenylphenyl)methoxy]benzaldehyde, Programmed Cell Death 1 Receptor, 6 dimethoxy 4 [(2 methyl 3 phenylphenyl)methoxy]phenyl]methyl]amino] 3 methylbutan 1 ol hydrochloride, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2, IC50, X ray analysis, Crystallography, X-Ray, B7-H1 Antigen, 1 [[3 bromo 4 [(2 methyl 3 phenylphenyl)methoxy]phenyl]methyl]piperidine 2 carboxylic acid, 0302 clinical medicine, Protein structure, Cancer immunotherapy, 6 dimethoxy 4 [(2 methyl 3 phenylphenyl)methoxy]benzaldehyde, 4 benzodioxin 6 yl) 2methylphenyl]methoxy] 2, Drug Discovery, Protein Interaction Maps, drug determination, 3 [4 chloro 5 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 formylphenoxymethyl]benzonitrile, dimerization, biology, 4 [[[4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2methylphenyl]methoxy] 2,5 difluorophenyl]methyl]amino] 3 hydroxybutanoic acid hydrochloride, Chemistry, heteronuclear multiple quantum coherence, article, Nuclear magnetic resonance spectroscopy, 5 difluorobenzaldehyde, protein function, Ligand (biochemistry), Small molecule, unclassified drug, 2 methoxy 6 [(2 methyl 3 phenylphenyl)methoxy]pyridine 3 carbaldehyde, Molecular Docking Simulation, 030220 oncology & carcinogenesis, [3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methanol, Molecular Medicine, [3 (2, medicine.drug_class, Stereochemistry, 3 dihydro 1, 2 [[[2 [(3 cyanophenyl)methoxy] 4 [[3 (2, 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2,5 difluorobenzaldehyde, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 hydroxybenzaldehyde, 3 [4 chloro 5 [[3 (2, Monoclonal antibody, oligomerization, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 5 methylphenyl] methyl]amino] 3 hydroxypropanoic acid hydrochloride, Small Molecule Libraries, 3 [5 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 formyl 4 methylphenoxymethyl]benzonitrile, 03 medical and health sciences, 3 bromo 4 [(2 methyl 3 phenylphenyl)methoxy]benzaldehyde, PD-L1, n [2 [[[2 methoxy 6 [(2 methyl 3 phenylphenyl)methoxy]pyridin 3 yl]methyl]amino]ethyl]acetamide hydrochloride, 5 chloro 4 [[3 (2, medicine, 3 [5 [[3 (2, (2 methyl 3 biphenylyl)methanol, Humans, 2 [[[2, human, protein interaction, protein structure, protein expression, hydrophobicity, nuclear magnetic resonance spectroscopy, 1 [[5 chloro 2 [(3 cyanophenyl)methoxy] 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy]phenyl] methyl] 4 hydroxypyrrolidine 2 carboxylic acid hydrochloride, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy]phenyl] methyl] 4 hydroxypyrrolidine 2 carboxylic acid hydrochloride, cancer immunotherapy, 2 [[[2,6 dimethoxy 4 [(2 methyl 3 phenylphenyl)methoxy]phenyl]methyl]amino] 3 methylbutan 1 ol hydrochloride, 5 difluorophenyl]methyl]amino] 3 hydroxybutanoic acid hydrochloride, 1 [[5 chloro 2 [(3 cyanophenyl)methoxy] 4 [[3 (2, Immune checkpoint, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 formylphenoxymethyl]benzonitrile, programmed death 1 ligand 1, drug structure, 030104 developmental biology, 4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 formyl 4 methylphenoxymethyl]benzonitrile, protein inhibitor, 2 [[[2 [(3 cyanophenyl)methoxy] 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 5 methylphenyl] methyl]amino] 3 hydroxypropanoic acid hydrochloride, 5 chloro 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 hydroxybenzaldehyde, 4 [[3 (2, biology.protein, drug synthesis, immunomodulating agent, 4 [[[4 [[3 (2, Protein Multimerization, 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 hydroxy 5 methylbenzaldehyde
وصف الملف: application/pdf
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المؤلفون: Jochem, Jerzy, Ottani, Alessandra, Giuliani, Daniela, Kasperska-Zajac, Alicja, Guarini, Salvatore
المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Fizyoloji Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Farmakoloji Anabilim Dalı., Altınbaş, Burçin, Yalçın, Murat, Savcı, Vahide, AAG-6956-2021
مصطلحات موضوعية: Leptin, Male, Rats, wistar, Histamine H3 receptor antagonist, Unclassified drug, Physiology, Microdialysis, Histaminergic system, Wistar rat, Procedures, Histamine H4 Receptors, Thioperamide, Intracerebroventricular Drug Administration, Tachycardia, Mechanisms, Responses, Intracerebroventricular drug administration, 1 (5 chloro 2 benzimidazolylcarbonyl) 4 methylpiperazine, Neurons, Histaminergic receptor affecting agent, Blood flow, Nerve cell, Mean arterial pressure, Cardiovascular system, Hemorrhagic shock, Blood pressure, Peripheral ischemia, Histamine receptor antagonist, Adrenergic system, Injections, intraventricular, Hypotension, Vasopressin, Receptor, Histamine, Chlorpheniramine, Vuf 5681, Heart rate, Ischemia/reperfusion, Ranitidine, Pathophysiology, Article, Shock, hemorrhagic, Proopiomelanocortin, Histamine agents, Animals, Animal model, Benzimidazole derivative, Animal experiment, Kidney blood flow, Histamine receptor, Drug effects, Haemorrhagic shock, Animal, Arterial-pressure, Induced reversal, Nonhuman, Rats, Release, Sympathetic nervous system, Regional blood flow, Mesentery blood flow, Rat, Benzimidazoles, Controlled study, High performance liquid chromatography
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______9458::f38b88e9279fcb2216063b3fafa7e588
http://hdl.handle.net/11452/29964
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