المؤلفون: Hull BT; Molecular and Cellular Biology Department, University of Arizona, Tucson, AZ 85721, USA., Miller KM; Cancer Biology Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ 85721, USA., Corban C; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Backer G; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Sheehan S; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Korstanje R; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Sutphin GL; Molecular and Cellular Biology Department, University of Arizona, Tucson, AZ 85721, USA.; Cancer Biology Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ 85721, USA.

المصدر: Biomolecules [Biomolecules] 2024 May 18; Vol. 14 (5). Date of Electronic Publication: 2024 May 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans*/drug effects , Caenorhabditis elegans*/metabolism , Caenorhabditis elegans*/genetics , Amyloid beta-Peptides*/metabolism , Amyloid beta-Peptides*/genetics , Peptides*/pharmacology , 3-Hydroxyanthranilic Acid*/metabolism , Paralysis*/chemically induced , Paralysis*/metabolism , Paralysis*/genetics, Animals ; Disease Models, Animal ; Alzheimer Disease/metabolism ; Alzheimer Disease/genetics ; Alzheimer Disease/drug therapy ; Caenorhabditis elegans Proteins/metabolism ; Caenorhabditis elegans Proteins/genetics ; Huntington Disease/metabolism ; Huntington Disease/genetics ; Dioxygenases/metabolism ; Dioxygenases/genetics

المؤلفون: Hetherington-Rauth M; California Pacific Medical Center, Research Institute, San Francisco, California, USA., Johnson E; California Pacific Medical Center, Research Institute, San Francisco, California, USA., Migliavacca E; Nestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland., Langsetmo L; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA., Hepple RT; Department of Physical Therapy, University of Florida, Gainesville, Florida, USA., Ryan TE; Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, Florida, USA., Ferrucci L; National Institute on Aging, National Institutes of Health, Gaithersburg, Maryland, USA., Breuillé D; Nestlé Institute of Food Safety and Analytical Sciences, Nestlé Research, Lausanne, Switzerland., Corthesy J; Nestlé Institute of Food Safety and Analytical Sciences, Nestlé Research, Lausanne, Switzerland., Lane NE; Division of Rheumatology, Department of Medicine, University of California, Davis, Davis, California, USA., Feige JN; Nestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.; School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Napoli N; Department of Medicine and Surgery, Research Unit of Endocrinology and Diabetes, Università Campus Bio-Medico di Roma, Rome, Italy.; Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy., Tramontana F; Department of Medicine and Surgery, Research Unit of Endocrinology and Diabetes, Università Campus Bio-Medico di Roma, Rome, Italy.; Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy., Orwoll ES; Department of Medicine, School of Medicine, Oregon Health and Science University, Portland, Oregon, USA., Cawthon PM; California Pacific Medical Center, Research Institute, San Francisco, California, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.

المصدر: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2024 Jul 01; Vol. 79 (7).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: published on behalf of the Gerontological Society of America by Oxford University Press Country of Publication: United States NLM ID: 9502837 Publication Model: Print Cited Medium: Internet ISSN: 1758-535X (Electronic) Linking ISSN: 10795006 NLM ISO Abbreviation: J Gerontol A Biol Sci Med Sci Subsets: MEDLINE

مواضيع طبية MeSH: Kynurenine*/metabolism , Kynurenine*/analogs & derivatives , Inflammation*/metabolism , Biomarkers*/metabolism , Tryptophan*/metabolism , Muscle, Skeletal*/metabolism, Humans ; Male ; Aged, 80 and over ; C-Reactive Protein/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Sarcopenia/metabolism ; 3-Hydroxyanthranilic Acid/metabolism ; Cytokines/metabolism ; Xanthurenates/metabolism

المؤلفون: Holthuijsen DDB; Department of Epidemiology, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands. Electronic address: d.holthuijsen@maastrichtuniversity.nl., van Roekel EH; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Bours MJL; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Ueland PM; Bevital AS, Bergen, Norway., Breukink SO; Department of Surgery, GROW School for Oncology and Reproduction, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands., Janssen-Heijnen MLG; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands; Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, the Netherlands., Keulen ETP; Department of Internal Medicine and Gastroenterology, Zuyderland Medical Centre Sittard-Geleen, Geleen, the Netherlands., Gigic B; Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany., Gsur A; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., Meyer K; Bevital AS, Bergen, Norway., Ose J; University of Utah, Salt Lake City, UT, USA; Huntsman Cancer Institute, Salt Lake City, UT, USA., Ulvik A; Bevital AS, Bergen, Norway., Weijenberg MP; Department of Epidemiology, GROW School for Oncology and Reproduction, Maastricht University, Maastricht, the Netherlands., Eussen SJPM; Department of Epidemiology, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands; Department of Epidemiology, CAPHRI School for Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands.

المصدر: Psychoneuroendocrinology [Psychoneuroendocrinology] 2024 May; Vol. 163, pp. 106981. Date of Electronic Publication: 2024 Jan 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 7612148 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3360 (Electronic) Linking ISSN: 03064530 NLM ISO Abbreviation: Psychoneuroendocrinology Subsets: MEDLINE

مواضيع طبية MeSH: Cancer Survivors* , Neoplasms*, Humans ; Kynurenine/metabolism ; Tryptophan/metabolism ; 3-Hydroxyanthranilic Acid/metabolism ; Depression ; Biomarkers ; Kynurenic Acid ; Anxiety

المؤلفون: Zeng J; Department of Emergency Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, P.R. China., Peng J; Department of Histology Embryology and Neurobiology, Sichuan University West China School of Basic Medical Sciences and Forensic Medicine, Chengdu, Sichuan, P.R. China., Jiang H; Department of Emergency Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, P.R. China., Deng P; Analytical and Testing Center, Sichuan University, Chengdu, Sichuan, P.R. China., Li K; Department of Emergency Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, P.R. China., Long D; Department of Emergency Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, P.R. China., Wang K; Department of Emergency Surgery, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, P.R. China.

المصدر: PloS one [PLoS One] 2022 Aug 16; Vol. 17 (8), pp. e0266730. Date of Electronic Publication: 2022 Aug 16 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid* , Tryptophan*, Biomarkers ; Colon ; Early Diagnosis ; Humans ; Kynurenic Acid ; Metabolome ; Metabolomics/methods ; Phenylalanine ; Proton Magnetic Resonance Spectroscopy/methods ; Tyrosine

المؤلفون: Dang H; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Castro-Portuguez R; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Espejo L; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Backer G; The Jackson Laboratory, Bar Harbor, ME, USA., Freitas S; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Spence E; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Meyers J; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Shuck K; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Gardea EA; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Chang LM; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Balsa J; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Thorns N; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA., Corban C; The Jackson Laboratory, Bar Harbor, ME, USA., Liu T; The Jackson Laboratory, Bar Harbor, ME, USA., Bean S; The Jackson Laboratory, Bar Harbor, ME, USA., Sheehan S; The Jackson Laboratory, Bar Harbor, ME, USA., Korstanje R; The Jackson Laboratory, Bar Harbor, ME, USA., Sutphin GL; Molecular & Cellular Biology, University of Arizona, Tucson, AZ, USA. sutphin@arizona.edu.

المصدر: Nature communications [Nat Commun] 2023 Dec 14; Vol. 14 (1), pp. 8338. Date of Electronic Publication: 2023 Dec 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Kynurenine*/metabolism , Caenorhabditis elegans Proteins*/genetics , Caenorhabditis elegans Proteins*/metabolism, Animals ; Male ; Female ; Mice ; Tryptophan/metabolism ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; 3-Hydroxyanthranilic Acid/metabolism ; Longevity/genetics ; Mice, Knockout

المؤلفون: Shi Z; Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Basic Medical Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Gan G; Department of Laboratory Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Gao X; Shanghai Profleader Biotech Co., Ltd, Shanghai, China., Chen F; Department of Laboratory Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Mi J; Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Basic Medical Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

المصدر: Clinical and translational medicine [Clin Transl Med] 2022 Feb; Vol. 12 (2), pp. e697.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326 (Electronic) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid/*metabolism , Carcinoma, Hepatocellular/*physiopathology , Kynurenine 3-Monooxygenase/*biosynthesis, 3-Hydroxyanthranilic Acid/pharmacology ; Apoptosis/drug effects ; Carcinoma, Hepatocellular/genetics ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/physiopathology

عنوان ترانسليتريتد: Tsinnabarinovaya kislota kak potentsial'nyi prognosticheskii marker shizofrenii.

المؤلفون: Shilov YE; Mental Health Research Center, Moscow, Russia., Baymeeva NV; Mental Health Research Center, Moscow, Russia., Brusov OS; Mental Health Research Center, Moscow, Russia., Oleichik IV; Mental Health Research Center, Moscow, Russia., Sizov SV; Mental Health Research Center, Moscow, Russia., Tyurin IA; Sklifosovsky Research Institute of Emergency Medicine of Department of Health of Moscow, Moscow, Russia.

المصدر: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2022; Vol. 122 (12), pp. 138-142.

نوع المنشور: English Abstract; Journal Article

بيانات الدورية: Publisher: Media Sfera Country of Publication: Russia (Federation) NLM ID: 9712194 Publication Model: Print Cited Medium: Print ISSN: 1997-7298 (Print) Linking ISSN: 19977298 NLM ISO Abbreviation: Zh Nevrol Psikhiatr Im S S Korsakova Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid* , Schizophrenia*, Humans ; Female ; Prognosis ; Oxazines ; Kynurenine

المؤلفون: Liu K; State Key Laboratory of Biobased Material and Green Papermaking (LBMP), School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China., Li L; State Key Laboratory of Biobased Material and Green Papermaking (LBMP), School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China. liling33802400@qlu.edu.cn.; Shandong Provincial Key Laboratory of Applied Microbiology, Ecology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250103, People's Republic of China. liling33802400@qlu.edu.cn., Yao W; State Key Laboratory of Biobased Material and Green Papermaking (LBMP), School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China., Wang W; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, People's Republic of China. weiwang100@sjtu.edu.cn., Huang Y; Shandong Provincial Key Laboratory of Applied Microbiology, Ecology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250103, People's Republic of China., Wang R; State Key Laboratory of Biobased Material and Green Papermaking (LBMP), School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China., Li P; State Key Laboratory of Biobased Material and Green Papermaking (LBMP), School of Bioengineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, Shandong, People's Republic of China.

المصدر: Scientific reports [Sci Rep] 2021 Aug 12; Vol. 11 (1), pp. 16451. Date of Electronic Publication: 2021 Aug 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid/*metabolism , Pseudomonas chlororaphis/*genetics, 3-Hydroxyanthranilic Acid/chemistry ; Culture Media ; Fermentation ; Ferric Compounds/metabolism ; Gene Knockdown Techniques ; Genes, Bacterial ; Genes, Regulator ; Phenazines/metabolism

المؤلفون: Ding Y; State Key Laboratory of Microbial Resources & CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang M; State Key Laboratory of Microbial Resources & CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Li J; State Key Laboratory of Microbial Resources & CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China., Li P; State Key Laboratory of Microbial Resources & CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Guo Z; State Key Laboratory of Microbial Resources & CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Chen Y; State Key Laboratory of Microbial Resources & CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: chenyihua@im.ac.cn.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Mar 05; Vol. 543, pp. 8-14. Date of Electronic Publication: 2021 Jan 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid/*metabolism , Anti-Bacterial Agents/*biosynthesis , Cyclohexenes/*metabolism , Disaccharides/*biosynthesis , Mixed Function Oxygenases/*metabolism , Streptomyces/*enzymology, 3-Hydroxyanthranilic Acid/chemistry ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Cyclohexenes/chemistry ; Cyclohexenes/pharmacology ; Disaccharides/chemistry ; Disaccharides/pharmacology ; Gram-Positive Bacteria/drug effects ; Mixed Function Oxygenases/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Streptomyces/chemistry ; Streptomyces/genetics

المؤلفون: Berg M; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Polyzos KA; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Agardh H; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Baumgartner R; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Forteza MJ; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Kareinen I; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Gisterå A; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Bottcher G; Pathology, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, SE-43189 Gothenburg, Sweden., Hurt-Camejo E; Cardiovascular, Renal and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, SE-43183 Gothenburg, Sweden., Hansson GK; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Ketelhuth DFJ; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, SE-17176 Stockholm, Sweden.

المصدر: Cardiovascular research [Cardiovasc Res] 2020 Oct 01; Vol. 116 (12), pp. 1948-1957.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: 3-Hydroxyanthranilic Acid/*metabolism , Atherosclerosis/*metabolism , Inflammasomes/*metabolism , Lipoproteins/*blood , Liver/*metabolism , Macrophages/*metabolism , Receptors, LDL/*deficiency , Sterol Regulatory Element Binding Protein 2/*metabolism, 3-Hydroxyanthranilate 3,4-Dioxygenase/antagonists & inhibitors ; 3-Hydroxyanthranilate 3,4-Dioxygenase/metabolism ; 3-Hydroxyanthranilic Acid/analogs & derivatives ; 3-Hydroxyanthranilic Acid/pharmacology ; Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Atherosclerosis/prevention & control ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Hep G2 Cells ; Humans ; Interleukin-1beta/metabolism ; Liver/drug effects ; Macrophages/drug effects ; Macrophages/pathology ; Mice, Inbred C57BL ; Mice, Knockout ; Plaque, Atherosclerotic ; Receptors, LDL/genetics ; Signal Transduction ; Sterol Regulatory Element Binding Protein 2/genetics