المؤلفون: Cai J; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Zhou Q; Key Laboratory of Tropical Biological Resources of Ministry of Education and Hainan Engineering Research Center for Drug Screening and Evaluation, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; Song Li' Academician Workstation of Hainan University (School of Pharmaceutical Sciences), Yazhou Bay, Sanya 572000, China., Qi X; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China., Zhang F; Key Laboratory of Tropical Biological Resources of Ministry of Education and Hainan Engineering Research Center for Drug Screening and Evaluation, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; Song Li' Academician Workstation of Hainan University (School of Pharmaceutical Sciences), Yazhou Bay, Sanya 572000, China., Yang J; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Chen C; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.; University of Chinese Academy of Sciences, Beijing 100049, China., Zhang K; Key Laboratory of Tropical Biological Resources of Ministry of Education and Hainan Engineering Research Center for Drug Screening and Evaluation, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; Song Li' Academician Workstation of Hainan University (School of Pharmaceutical Sciences), Yazhou Bay, Sanya 572000, China., Chen Z; Key Laboratory of Tropical Biological Resources of Ministry of Education and Hainan Engineering Research Center for Drug Screening and Evaluation, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; Song Li' Academician Workstation of Hainan University (School of Pharmaceutical Sciences), Yazhou Bay, Sanya 572000, China., Luo HB; Key Laboratory of Tropical Biological Resources of Ministry of Education and Hainan Engineering Research Center for Drug Screening and Evaluation, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; Song Li' Academician Workstation of Hainan University (School of Pharmaceutical Sciences), Yazhou Bay, Sanya 572000, China., Liu Y; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China., Huang YY; Key Laboratory of Tropical Biological Resources of Ministry of Education and Hainan Engineering Research Center for Drug Screening and Evaluation, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.; Song Li' Academician Workstation of Hainan University (School of Pharmaceutical Sciences), Yazhou Bay, Sanya 572000, China., Zhou X; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.; University of Chinese Academy of Sciences, Beijing 100049, China.

المصدر: Journal of natural products [J Nat Prod] 2024 Jul 26; Vol. 87 (7), pp. 1808-1816. Date of Electronic Publication: 2024 Jun 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Pharmacognosy Country of Publication: United States NLM ID: 7906882 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6025 (Electronic) Linking ISSN: 01633864 NLM ISO Abbreviation: J Nat Prod Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 4 Inhibitors*/pharmacology , Phosphodiesterase 4 Inhibitors*/chemistry , Phosphodiesterase 4 Inhibitors*/isolation & purification , Terphenyl Compounds*/pharmacology , Terphenyl Compounds*/chemistry , Terphenyl Compounds*/isolation & purification, Mice ; Animals ; Molecular Structure ; Talaromyces/chemistry ; RAW 264.7 Cells ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Marine Biology

المؤلفون: Griffin H; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Hanson J; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Phelan KD; Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Baldini G; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

المصدر: Cells [Cells] 2024 Jul 23; Vol. 13 (15). Date of Electronic Publication: 2024 Jul 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Receptor, Melanocortin, Type 4*/metabolism , Receptor, Melanocortin, Type 4*/genetics , Neurons*/metabolism , Hypothalamus*/metabolism , Hypothalamus*/cytology, Animals ; Mice ; Synapses/metabolism ; Disks Large Homolog 4 Protein/metabolism ; Cells, Cultured ; Receptors, N-Methyl-D-Aspartate/metabolism

المؤلفون: Bozkurt A; Faculty of Pharmacy, Department of Pharmacology, Van Yuzuncu Yil University, Van, Turkey., Karakoy Z; Faculty of Pharmacy, Department of Pharmacology, Erzincan Binali Yildirim University, Erzincan, Turkey., Aydin P; Faculty of Medicine, Department of Pharmacology, Ataturk University, Erzurum, 25240, Turkey.; Department of Anesthesiology and Reanimation, Educational and Research Hospital, Erzurum, Turkey., Ozdemir B; Faculty of Medicine, Department of Histology and Embryology, Kafkas University, Kars, Turkey., Toktay E; Faculty of Medicine, Department of Histology and Embryology, Kafkas University, Kars, Turkey., Halici Z; Faculty of Medicine, Department of Pharmacology, Ataturk University, Erzurum, 25240, Turkey.; Clinical Research, Development and Design Application and Research Center, Ataturk University, 25240, Erzurum, Turkey., Cadirci E; Faculty of Medicine, Department of Pharmacology, Ataturk University, Erzurum, 25240, Turkey. ecadirci@atauni.edu.tr.; Clinical Research, Development and Design Application and Research Center, Ataturk University, 25240, Erzurum, Turkey. ecadirci@atauni.edu.tr.

المصدر: Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2024 Jul; Vol. 31 (7), pp. 2021-2031. Date of Electronic Publication: 2024 Mar 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 4 Inhibitors*/pharmacology , Phosphodiesterase 4 Inhibitors*/therapeutic use , Reperfusion Injury*/drug therapy , Reperfusion Injury*/metabolism , Reperfusion Injury*/pathology , Rolipram*/pharmacology , Rolipram*/therapeutic use , Ovary*/drug effects , Ovary*/pathology , Ovary*/metabolism , Ovary*/blood supply , Aquaporin 5*/metabolism, Animals ; Female ; Rats ; Cyclic AMP/metabolism ; NF-kappa B/metabolism ; NF-kappa B/antagonists & inhibitors ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-6/metabolism ; Signal Transduction/drug effects ; Rats, Sprague-Dawley

المؤلفون: Nummela P; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Pathology, HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Zafar S; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Pathology, HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Veikkolainen E; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Pathology, HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Ukkola I; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Pathology, HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Cinella V; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Pathology, HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Ayo A; Translational Cancer Medicine Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland., Asghar MY; Cell and Tissue Dynamics Research Program, Institute of Biotechnology, HiLife, University of Helsinki, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Välimäki N; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland., Törnquist K; Minerva Foundation Institute for Medical Research, Helsinki, Finland.; Faculty of Science and Engineering, Cell Biology, Åbo Akademi University, Turku, Finland., Karhu A; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland., Laakkonen P; Translational Cancer Medicine Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland., Aaltonen LA; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland., Ristimäki A; Applied Tumor Genomics Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland.; Department of Pathology, HUSLAB, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

المصدر: International journal of cancer [Int J Cancer] 2024 Jun 01; Vol. 154 (11), pp. 1987-1998. Date of Electronic Publication: 2024 Feb 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Chromogranins*/genetics , Chromogranins*/metabolism , Colorectal Neoplasms*/genetics , Cyclic Nucleotide Phosphodiesterases, Type 4*/genetics , Cyclic Nucleotide Phosphodiesterases, Type 4*/metabolism , GTP-Binding Protein alpha Subunits, Gs*/genetics , GTP-Binding Protein alpha Subunits, Gs*/metabolism, Animals ; Humans ; Mice ; HCT116 Cells ; Mice, Nude ; Mutation ; Phosphodiesterase 4 Inhibitors/pharmacology

المؤلفون: Chen K; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Xu B; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Qiu S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Long L; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Zhao Q; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Xu J; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.; Key Laboratory of Mental Health of the Ministry of Education, Southern Medical University, Guangzhou, China.; Center for Brain Science and Brain-Inspired Intelligence, Guangdong-Hong Kong-Macao Greater Bay Area, Guangzhou, China., Wang H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.; Key Laboratory of Mental Health of the Ministry of Education, Southern Medical University, Guangzhou, China.; Center for Brain Science and Brain-Inspired Intelligence, Guangdong-Hong Kong-Macao Greater Bay Area, Guangzhou, China.

المصدر: Glia [Glia] 2024 Sep; Vol. 72 (9), pp. 1629-1645. Date of Electronic Publication: 2024 May 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE

مواضيع طبية MeSH: Aquaporin 4*/metabolism , Aquaporin 4*/genetics , Astrocytes*/metabolism , Astrocytes*/drug effects , Reperfusion Injury*/metabolism , Phosphodiesterase 4 Inhibitors*/pharmacology , Rats, Sprague-Dawley* , Brain Edema*/metabolism , Brain Edema*/etiology , Brain Edema*/pathology , Aminopyridines*/pharmacology , Benzamides*/pharmacology , Infarction, Middle Cerebral Artery*, Animals ; Male ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Cyclopropanes/pharmacology ; Forkhead Box Protein O3/metabolism ; Rats ; Proto-Oncogene Proteins c-akt/metabolism ; Cells, Cultured ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Disease Models, Animal ; Interleukin-1beta/metabolism

المؤلفون: Xia C; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China., Wen H; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China., Zheng L; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China., Ni Y; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China., Bi H; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China., Wang H; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China., Xu J; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address: jpx@smu.edu.cn., Zhou ZZ; Innovation Program of Drug Research on Neurological and Metabolic Diseases, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China. Electronic address: zhouzz@smu.edu.cn.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Sep 05; Vol. 275, pp. 116576. Date of Electronic Publication: 2024 Jun 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Benzofurans*/pharmacology , Benzofurans*/chemistry , Benzofurans*/chemical synthesis , Galactosamine*/pharmacology , Phosphodiesterase 4 Inhibitors*/pharmacology , Phosphodiesterase 4 Inhibitors*/chemistry , Phosphodiesterase 4 Inhibitors*/chemical synthesis , Sepsis*/drug therapy, Animals ; Humans ; Male ; Rats ; Chemical and Drug Induced Liver Injury/drug therapy ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Dose-Response Relationship, Drug ; Drug Discovery ; Lipopolysaccharides/pharmacology ; Lipopolysaccharides/antagonists & inhibitors ; Liver/drug effects ; Liver/pathology ; Molecular Docking Simulation ; Molecular Structure ; Protective Agents/pharmacology ; Protective Agents/chemistry ; Protective Agents/chemical synthesis ; Rats, Sprague-Dawley ; Structure-Activity Relationship

المؤلفون: Safe S; Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA. ssafe@cvm.tamu.edu.

المصدر: Histology and histopathology [Histol Histopathol] 2024 May; Vol. 39 (5), pp. 543-556. Date of Electronic Publication: 2023 Dec 13.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Histology and Histopathology Country of Publication: Spain NLM ID: 8609357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-5848 (Electronic) Linking ISSN: 02133911 NLM ISO Abbreviation: Histol Histopathol Subsets: MEDLINE

مواضيع طبية MeSH: Biological Products*/pharmacology , Biological Products*/therapeutic use , Biological Products*/chemistry , Nuclear Receptor Subfamily 4, Group A, Member 1*/metabolism, Humans ; Animals ; Nuclear Receptor Subfamily 4, Group A, Member 2/metabolism ; Ligands ; DNA-Binding Proteins/metabolism ; Nuclear Receptor Subfamily 4, Group A, Member 3/metabolism ; Receptors, Steroid/metabolism ; Receptors, Thyroid Hormone/metabolism

المؤلفون: Nongthombam PD; Department of Biotechnology, Manipur University, Canchipur, Imphal, 795003, India., Haobam R; Department of Biotechnology, Manipur University, Canchipur, Imphal, 795003, India. reena_haobam@rediffmail.com.

المصدر: Molecular biology reports [Mol Biol Rep] 2024 Apr 15; Vol. 51 (1), pp. 510. Date of Electronic Publication: 2024 Apr 15.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

مواضيع طبية MeSH: Parkinson Disease*/drug therapy , Phosphodiesterase 4 Inhibitors*/pharmacology , Phosphodiesterase 4 Inhibitors*/therapeutic use , Neurodegenerative Diseases*/metabolism, Diethylstilbestrol/*analogs & derivatives, Animals ; Humans ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Cyclic AMP/metabolism ; Cyclic GMP/metabolism ; Mammals/metabolism

المؤلفون: Zou GJ; Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China; School of Basic Medicine, Yiyang Medical College, Yiyang, Hunan, 413000, China., Chen ZR; Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China; Hunan University of Chinese Medicine, Changsha, Hunan, 410219, China., Wang XQ; Hunan Provincial University Key Laboratory of the Fundamental and Clinical Research on Neurodegenerative Diseases, Changsha Medical University, Changsha, Hunan, 410219, China., Cui YH; Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China., Li F; Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China., Li CQ; Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China., Wang LF; Hunan Provincial University Key Laboratory of the Fundamental and Clinical Research on Neurodegenerative Diseases, Changsha Medical University, Changsha, Hunan, 410219, China. Electronic address: laifawang@126.com., Huang FL; School of Basic Medicine, Yiyang Medical College, Yiyang, Hunan, 413000, China. Electronic address: hflscience@126.com.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2024 Sep 05; Vol. 978, pp. 176759. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Fear*/physiology , Fear*/psychology , Prefrontal Cortex*/metabolism , Prefrontal Cortex*/physiology , Microglia*/metabolism , Extinction, Psychological*/physiology , Mental Recall*/physiology , Mice, Inbred C57BL* , Kruppel-Like Factor 4*, Animals ; Male ; Mice ; Microfilament Proteins/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Disks Large Homolog 4 Protein/metabolism ; Acoustic Stimulation/adverse effects ; Signal Transduction

المؤلفون: Takahashi K; Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan; Department of Human Pathology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Miyake K; Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. Electronic address: miyake.mbch@tmd.ac.jp., Ito J; Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Shimamura H; Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan; Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan., Suenaga T; Department of Immunology, Kitasato University School of Medicine, Sagamihara, Japan., Karasuyama H; Inflammation, Infection and Immunity Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Ohashi K; Department of Human Pathology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

المصدر: The Journal of investigative dermatology [J Invest Dermatol] 2024 May; Vol. 144 (5), pp. 1048-1057.e8. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Dermatitis, Atopic*/drug therapy , Dermatitis, Atopic*/pathology , Dermatitis, Atopic*/immunology , Dermatitis, Atopic*/chemically induced , Phosphodiesterase 4 Inhibitors*/pharmacology , Phosphodiesterase 4 Inhibitors*/administration & dosage , Phosphodiesterase 4 Inhibitors*/therapeutic use , Interleukin-4*/metabolism , Basophils*/drug effects , Basophils*/metabolism , Basophils*/immunology , Disease Models, Animal* , Phthalic Acids* , Quinazolines*, Animals ; Mice ; Administration, Topical ; Oxazolone ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Mice, Inbred C57BL ; Skin/pathology ; Skin/drug effects ; Skin/metabolism ; Humans ; Mice, Knockout ; Female