المؤلفون: Mahek Sadiq, Lizhi Pang, Michael Johnson, Venkatachalem Sathish, Qifeng Zhang, Danling Wang

المصدر: Biosensors, Vol 11, Iss 2, p 40 (2021)

مصطلحات موضوعية: 2D Ti3C2 MXene, PGE2, 8-HOA, lung cancer, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2079-6374/11/2/40; https://doaj.org/toc/2079-6374

URL الوصول: https://doaj.org/article/bcdce2b7ecea4f3083165bb87633f5af

المؤلفون: Harshit Shah, Lizhi Pang, Steven Y. Qian, Yi Xu

المصدر: Translational Oncology, Vol 14, Iss 11, Pp 101207-(2021)
Translational Oncology

مصطلحات موضوعية: Cancer Research, EDA, eicosadienoic acid, MDSCs, myeloid-derived suppressor cells, 5-LOX, 5-lipoxygenase, Prostaglandin E2, AA, arachidonic acid, Review, 8-HOA, 8-hydroxyoctanoic acid, POBN, α-(4-Pyridyl 1-oxide)-N-tert-butylnitrone, chemistry.chemical_compound, ETA, eicosatetraenoic acid, SNP, single-nucleotide acid polymorphism, RNA interference, ELOVL5, elongation of very long-chain fatty acid protein 5, HDAC, histone deacetylases, Medicine, Receptor, RC254-282, chemistry.chemical_classification, TCGA, the cancer genome atlas, TME, tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Delta-5 desaturase, PGs, prostaglandins, LTs, leukotrienes, MMP, matrix metalloproteinase, Tumor inflammation, D5D, delta-5-desaturase, RNAi, RNA interference, EpCAM, epithelial cell adhesion molecule, Oncology, COX-2, cyclooxygenase-2, GPX4, glutathione peroxidase 4, TAZ, transcriptional coactivator with PDZ-binding motif, Arachidonic acid, EMT, epithelial-mesenchymal transition, Polyunsaturated fatty acid metabolism, Programmed cell death, RXR, retinoid X receptor, SREBP-1c, sterol regulatory element-binding protein 1c, 8-hydroxyoctanoic acid, ER, endoplasmic reticulum, DNMT3B, DNA methyltransferase 3B, ROS, reactive oxygen species, PGE2, prostaglandin E2, DGLA, dihomo-γ-linolenic acid, 5-FU, fluorouracil, 3WJ, 3-way junction, PPARα, peroxisome proliferator-activated receptor α, Fatty acid metabolism, business.industry, PUFAs, polyunsaturated fatty acids, Cancer, EPA, eicosapentaenoic acid, medicine.disease, Bax, Bcl-2-associated X protein, Enzyme, chemistry, Cancer cell, Cancer research, HAT, histone acetyltransferase, LXR, liver X receptor, business, YAP1, yes-associated protein-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81cba5e09eeffe1477f02b7b3cd5fa8
http://www.sciencedirect.com/science/article/pii/S1936523321001996

المؤلفون: Di Gao, Yi Xu, Steven Y. Qian, Liu Yang, Xiaoyu Yang

المصدر: Redox Biology
Redox Biology, Vol 20, Iss, Pp 236-246 (2019)

مصطلحات موضوعية: 0301 basic medicine, Fatty Acid Desaturases, Clinical Biochemistry, AA, arachidonic acid, HDAC, histone deacetylase, Apoptosis, 8-HOA, 8-hydroxyoctanoic acid, Biochemistry, Deoxycytidine, Small hairpin RNA, chemistry.chemical_compound, Mice, 0302 clinical medicine, 8,11,14-Eicosatrienoic Acid, Delta-5 Fatty Acid Desaturase, Pancreatic cancer growth and migration, COX-2 catalyzed DGLA peroxidation, wt-D5D, wild type D5D, Neoplasm Metastasis, RNA, Small Interfering, lcsh:QH301-705.5, lcsh:R5-920, Gene knockdown, Chemistry, Drug Synergism, 3. Good health, Gene Expression Regulation, Neoplastic, D5D, delta-5-desaturase, Arachidonic acid, Female, RNA Interference, lcsh:Medicine (General), medicine.drug, Research Paper, Antineoplastic Agents, COX, Cyclooxygenase, 03 medical and health sciences, Pancreatic cancer, Cell Line, Tumor, medicine, PGE2, prostaglandin E2, DGLA, dihomo-γ-linolenic acid, Animals, Humans, Cell Proliferation, Neoplasm Staging, Dihomo-γ-linolenic acid, Organic Chemistry, Xenograft tumor, medicine.disease, Xenograft Model Antitumor Assays, Gemcitabine, Pancreatic Neoplasms, Disease Models, Animal, 030104 developmental biology, lcsh:Biology (General), D5D-KD, delta-5-desaturase knockdown, Cancer cell, Delta-5-desaturase knockdown, Cancer research, 030217 neurology & neurosurgery, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fdf9810a22ba97ea18315f725a35934
http://europepmc.org/articles/PMC6205412

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المؤلفون: Yi Xu, Tao Wang, Steven Y. Qian, Dan Shu, Xiaoyu Yang, Keith Miskimins, Peixuan Guo

المصدر: Redox Biology
Redox Biology, Vol 12, Iss, Pp 1062-(2017)

مصطلحات موضوعية: Fatty Acid Desaturases, 0301 basic medicine, Clinical Biochemistry, Inhibition of histone deacetylase, AA, arachidonic acid, HDAC, histone deacetylase, 8-HOA, 8-hydroxyoctanoic acid, Biochemistry, Delta-5 Fatty Acid Desaturase, 0302 clinical medicine, Cell Movement, NC-sh, negative control shRNA transfected, lcsh:QH301-705.5, HDACi, histone deacetylase inhibitor, lcsh:R5-920, Chemistry, ShRNA transfection, Gene Expression Regulation, Neoplastic, D5D, delta-5-desaturase, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, Colonic Neoplasms, Matrix Metalloproteinase 2, lcsh:Medicine (General), Research Paper, COX, Cyclooxygenase, EMT, epithelial mesenchymal transition, Redox, Article, 03 medical and health sciences, PBS, phosphate buffered saline, Cell Line, Tumor, medicine, Humans, DGLA, dihomo-γ-linolenic acid, Neoplasm Invasiveness, 5-FU, 5-flurouracil, Delta 5 desaturase, Organic Chemistry, Cancer, COX-catalyzed DGLA peroxidation, medicine.disease, 5-fluorouracil and gemcitabine, Pancreatic Neoplasms, Cancer migration and invasion, 030104 developmental biology, lcsh:Biology (General), Cyclooxygenase 2, D5D-KD, delta-5-desaturase knockdown, Cancer cell, Delta-5-desaturase knockdown, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd003faf8df3c0ab0458a897e4efaba
https://pubmed.ncbi.nlm.nih.gov/28157665

المؤلفون: Steven Y. Qian, Yi Xu, Xiaoyu Yang, Jin Qi, Erxi Wu

المصدر: Redox Biology
Redox Biology, Vol 2, Iss C, Pp 610-618 (2014)

مصطلحات موضوعية: Clinical Biochemistry, DHA, docosahexaenoic acid, AA, arachidonic acid, Apoptosis, 8-HOA, 8-hydroxyoctanoic acid, Pharmacology, COX-catalyzed PUFA peroxidation, Biochemistry, Lipid peroxidation, chemistry.chemical_compound, 8,11,14-Eicosatrienoic Acid, 5-FU, 5-Fluorouracil, HPLC/LC, high performance liquid chromatography, Cell cycle and apoptosis, lcsh:QH301-705.5, D5D, delta-5 desaturase, chemistry.chemical_classification, lcsh:R5-920, biology, Cell Cycle, Combination chemotherapy, HEX, 1-hexanol, TBS, Tris buffered saline, PGs, prostaglandins, 3. Good health, SPE, solid phase extraction, Colonic Neoplasms, ESR, electron spin resonance, Arachidonic acid, HTA, heptanoic acid, Fluorouracil, lcsh:Medicine (General), GC, gas chromatography, Colon cancer cell line HCA-7 colony 29, Polyunsaturated fatty acid, Free Radicals, 5-Fluorouracil, Antineoplastic Agents, Article, PI, propidium iodide, Structure-Activity Relationship, TIC, total ion chromatogram, Cell Line, Tumor, PUFA, polyunsaturated fatty acid, Humans, POBN, α-[4-pyridyl-1-oxide]-N-tert-butyl nitrone, Cell Proliferation, Dihomo-γ-linolenic acid, Dose-Response Relationship, Drug, Cell growth, Organic Chemistry, Fatty acid, LC/MS and ESR spin trapping, ACN, acetonitrile, EPA, eicosapentaenoic acid, EIC, extracted ion chromatogram, COX, cyclooxygenase, lcsh:Biology (General), chemistry, MS, mass spectrometry, DGLA׳s free radical derivatives, DGLA, dihomo-γ-linoleic acid, Prostaglandin-Endoperoxide Synthases, biology.protein, HOAc, glacial acetic acid, Biocatalysis, Cyclooxygenase, Lipid Peroxidation, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bab9c77ae0903efef043fb745dd8cc

المؤلفون: Steven Y. Qian, Dan Shu, Hongzhi Wang, Peixuan Guo, Harshit Shah, Congcong Xu, Lizhi Pang, Yi Xu

المصدر: Redox Biology, Vol 21, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: Fatty Acid Desaturases, 0301 basic medicine, Knockdown of delta-5-desaturase, Colorectal cancer, Clinical Biochemistry, AA, arachidonic acid, HDAC, histone deacetylase, Apoptosis, 8-HOA, 8-hydroxyoctanoic acid, Biochemistry, Mice, chemistry.chemical_compound, 8,11,14-Eicosatrienoic Acid, Delta-5 Fatty Acid Desaturase, 0302 clinical medicine, RNA, Small Interfering, lcsh:QH301-705.5, Cells, Cultured, lcsh:R5-920, Chemistry, COX-2-catalyzed DGLA peroxidation, 3. Good health, D5D, delta-5-desaturase, Colonic Neoplasms, lcsh:Medicine (General), Research Paper, COX, Cyclooxygenase, RNA 3WJ nanoparticle, 03 medical and health sciences, Downregulation and upregulation, In vivo, Cell Line, Tumor, medicine, DGLA, dihomo-γ-linolenic acid, Animals, Humans, HCA-7 colony 29 cells, HCA-7/C29, HCA-7 colony 29 cells, 3WJ nanoparticle, three way junction nanoparticle, Tumor suppression, Cell Proliferation, Dihomo-γ-linolenic acid, Organic Chemistry, RNA, medicine.disease, Xenograft Model Antitumor Assays, In vitro, 030104 developmental biology, lcsh:Biology (General), Cancer cell, Cancer research, Nanoparticles, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f939ae9d35199a8ff4763bc3b88f227f
https://doi.org/10.1016/j.redox.2018.101085

المؤلفون: Xu Y; Department of Pharmaceutical Sciences, College of Pharmacy, Nursing and Allied Sciences, North Dakota State University, Fargo, ND 58108, USA., Qi J; Department of Pharmaceutical Sciences, College of Pharmacy, Nursing and Allied Sciences, North Dakota State University, Fargo, ND 58108, USA ; Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, Jiangsu 211198, China., Yang X; Department of Pharmaceutical Sciences, College of Pharmacy, Nursing and Allied Sciences, North Dakota State University, Fargo, ND 58108, USA., Wu E; Department of Pharmaceutical Sciences, College of Pharmacy, Nursing and Allied Sciences, North Dakota State University, Fargo, ND 58108, USA., Qian SY; Department of Pharmaceutical Sciences, College of Pharmacy, Nursing and Allied Sciences, North Dakota State University, Fargo, ND 58108, USA.

المصدر: Redox biology [Redox Biol] 2014 Mar 20; Vol. 2, pp. 610-8. Date of Electronic Publication: 2014 Mar 20 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: eCollection Cited Medium: Print ISSN: 2213-2317 (Print) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Peroxidation*, 8,11,14-Eicosatrienoic Acid/*metabolism , Antineoplastic Agents/*pharmacology , Colonic Neoplasms/*pathology , Fluorouracil/*pharmacology , Free Radicals/*metabolism , Prostaglandin-Endoperoxide Synthases/*metabolism, 8,11,14-Eicosatrienoic Acid/chemistry ; Apoptosis/drug effects ; Biocatalysis ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Colonic Neoplasms/metabolism ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Free Radicals/chemistry ; Humans ; Structure-Activity Relationship