المؤلفون: Jatzlau, Jerome, Burdzinski, Wiktor, Trumpp, Michael, Obendorf, Leon, Roßmann, Kilian, Ravn, Katharina, Hyvönen, Marko, Bottanelli, Francesca, Broichhagen, Johannes, Knaus, Petra

المساهمون: Jatzlau, Jerome [0000-0002-1757-0267], Burdzinski, Wiktor [0000-0002-4495-5779], Trumpp, Michael [0000-0002-6151-9151], Hyvönen, Marko [0000-0001-8683-4070], Broichhagen, Johannes [0000-0003-3084-6595], Knaus, Petra [0000-0003-2492-1667], Apollo - University of Cambridge Repository

مصطلحات موضوعية: 631/80/2373, 631/80/86, article, Medicine (miscellaneous), 500 Naturwissenschaften und Mathematik::570 Biowissenschaften, Biologie::570 Biowissenschaften, Biologie, Bone Morphogenetic Protein Receptors, Cellular imaging, Ligands, 14, General Biochemistry, Genetics and Molecular Biology, 96/63, 96/95, 14/34, Transforming Growth Factor beta, Bone Morphogenetic Proteins, Membrane proteins, 631/45/612/1237, General Agricultural and Biological Sciences, Receptors, Transforming Growth Factor beta, Cell signalling

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https://doi.org/10.1038/s42003-022-04388-4

المؤلفون: Qin Yu, Yorgo Modis, Alba Herrero del Valle, Rahul Singh

المساهمون: Yu, Qin [0000-0001-9265-632X], Herrero Del Valle, Alba [0000-0001-8153-6146], Singh, Rahul [0000-0001-8397-0202], Modis, Yorgo [0000-0002-6084-0429], Apollo - University of Cambridge Repository, Herrero del Valle, Alba [0000-0001-8153-6146]

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, 12 (1)
Nature Communications

مصطلحات موضوعية: Models, Molecular, 82/29, Interferon-Induced Helicase, IFIH1, Protein Conformation, ATPase, viruses, General Physics and Astronomy, medicine.disease_cause, 631/45/173, 631/45/535/1258/1259, Adenosine Triphosphate, 0302 clinical medicine, ATP hydrolysis, Interferon, Adenosine Triphosphatases, 0303 health sciences, Mutation, Multidisciplinary, biology, Chemistry, 631/45/500, article, food and beverages, MDA5, Chronic inflammation, 3. Good health, Cell biology, RNA silencing, Enzyme mechanisms, RNA, Viral, Protein Binding, medicine.drug, Science, Allosteric regulation, Mutation, Missense, General Biochemistry, Genetics and Molecular Biology, 96/95, 03 medical and health sciences, medicine, Humans, 82/83, RNA, Double-Stranded, 030304 developmental biology, Inflammation, 631/250/262/2106/2518, Cryoelectron Microscopy, 101/28, fungi, RNA, General Chemistry, Immunity, Innate, HEK293 Cells, 631/250/256/2515, RIG-I-like receptors, biology.protein, Nucleic Acid Conformation, 030217 neurology & neurosurgery

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https://doaj.org/article/4ed51115fdf7407f8d5ba6033a51c511

المؤلفون: Mangolini, Maurizio, Maiques-Diaz, Alba, Charalampopoulou, Stella, Gerhard-Hartmann, Elena, Bloehdorn, Johannes, Moore, Andrew, Giachetti, Giorgia, Lu, Junyan, Roamio Franklin, Valar Nila, Chilamakuri, Chandra Sekkar Reddy, Moutsopoulos, Ilias, Rosenwald, Andreas, Stilgenbauer, Stephan, Zenz, Thorsten, Mohorianu, Irina, D'Santos, Clive, Deaglio, Silvia, Hodson, Daniel J, Martin-Subero, Jose I, Ringshausen, Ingo

المساهمون: Maiques-Diaz, Alba [0000-0002-3365-3775], Bloehdorn, Johannes [0000-0003-1433-9702], Moore, Andrew [0000-0002-2875-6315], Lu, Junyan [0000-0002-9211-0746], Moutsopoulos, Ilias [0000-0003-4584-7849], Zenz, Thorsten [0000-0001-7890-9845], Deaglio, Silvia [0000-0003-0632-5036], Hodson, Daniel J [0000-0001-6225-2033], Martin-Subero, Jose I [0000-0001-8809-5195], Ringshausen, Ingo [0000-0002-7247-311X], Apollo - University of Cambridge Repository, University of Zurich, Ringshausen, Ingo

مصطلحات موضوعية: Lymphoma, 692/4028/67/1990/283/1895, General Physics and Astronomy, 45/44, 45/88, 610 Medicine & health, 1600 General Chemistry, 45/23, CD8-Positive T-Lymphocytes, 96/31, B7-H1 Antigen, General Biochemistry, Genetics and Molecular Biology, Epigenesis, Genetic, 96/95, Interferon-gamma, 1300 General Biochemistry, Genetics and Molecular Biology, 631/67/68, Humans, 96/2, Receptor, Notch2, 96/1, Receptor, Notch1, 1000 Multidisciplinary, Multidisciplinary, 96/109, article, General Chemistry, 45/15, 3100 General Physics and Astronomy, 10032 Clinic for Oncology and Hematology, 13/51, Signal Transduction

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المؤلفون: Remkes A. Scheele, Laurens H. Lindenburg, Maya Petek, Markus Schober, Kevin N. Dalby, Florian Hollfelder

المساهمون: Petek, Maya [0000-0002-4597-4162], Dalby, Kevin N [0000-0001-9272-5129], Hollfelder, Florian [0000-0002-1367-6312], Apollo - University of Cambridge Repository

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: endocrine system, MAP Kinase Signaling System, Science, 49/47, MAP Kinase Kinase 1, 49/23, General Physics and Astronomy, 96/35, 96/34, 631/45/275, General Biochemistry, Genetics and Molecular Biology, Catalysis, Phosphates, Substrate Specificity, 96/95, Protein Domains, Humans, Phosphorylation, Mitogen-Activated Protein Kinase 1, 49/31, Multidisciplinary, 631/45/603, article, Epistasis, Genetic, General Chemistry, 631/92/605, Protein-Tyrosine Kinases, Molecular Docking Simulation, 631/92/552, 631/1647/2163, Mitogen-Activated Protein Kinases, Protein Kinases, Signal Transduction

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المؤلفون: Petra Kodajova, Sonia Sánchez Martínez, Nicola A. Probst, Liam C. Lee, Ines Garces de los Fayos Alonso, Miaojun Han, Sandra Högler, Joaquín Pastor, G. A. Amos Burke, C. Patrick Reynolds, Hong Kai Lim, Eleanor Manners, Carmen Blanco-Aparicio, Leila Jahangiri, Jamie D. Matthews, Ji Luo, Suzanne D. Turner, Nina Prokoph, Simone Tangermann, Lukas Kenner, Olaf Merkel, Ricky M Trigg

المساهمون: Trigg, Ricky M. [0000-0001-9329-9344], Martinez, Sonia [0000-0003-2230-7794], Blanco-Aparicio, Carmen [0000-0002-3249-6595], Kenner, Lukas [0000-0003-2184-1338], Turner, Suzanne D. [0000-0002-8439-4507], Apollo - University of Cambridge Repository, Trigg, Ricky M [0000-0001-9329-9344], Turner, Suzanne D [0000-0002-8439-4507], Children with Cancer UK, Cancer Research UK (Reino Unido), European Research Council

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)

مصطلحات موضوعية: 0301 basic medicine, 82/29, 45/41, General Physics and Astronomy, Apoptosis, 45/47, 96/31, 13/2, 13/1, 38/1, 42/47, Mice, Neuroblastoma, 0302 clinical medicine, 42/89, hemic and lymphatic diseases, 38/23, 38/22, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Sulfones, lcsh:Science, 13/89, N-Myc Proto-Oncogene Protein, Multidisciplinary, Chemistry, 45/77, 3. Good health, Biphenyl compound, 13/31, Cancer therapeutic resistance, 631/67/1059/602, 030220 oncology & carcinogenesis, 631/67/2332, Gene Knockdown Techniques, 38/77, Thiazolidines, 64/60, 631/67/70, 82/1, medicine.drug, Brigatinib, medicine.drug_class, 631/67/1059/2326, Science, 49/22, 49/23, PIM1, 38/90, 45/22, 13/106, 45/23, 13/109, General Biochemistry, Genetics and Molecular Biology, Article, 96/95, Paediatric cancer, 03 medical and health sciences, Targeted therapies, Organophosphorus Compounds, Proto-Oncogene Proteins c-pim-1, Cell Line, Tumor, 38/89, medicine, Animals, Humans, 96/2, 96/1, Cancer models, Protein Kinase Inhibitors, 38/109, 96/106, Ceritinib, Biphenyl Compounds, General Chemistry, 64/110, medicine.disease, Xenograft Model Antitumor Assays, ALK inhibitor, 030104 developmental biology, Pyrimidines, Drug Resistance, Neoplasm, 13/51, 13/95, Cancer research, lcsh:Q, 82/51

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http://link.springer.com/article/10.1038/s41467-019-13315-x

المؤلفون: Claire L Meek, Geoffrey P. Roberts, Tristan J Vaughan, Richard G. Kay, Florent Serge Dye, Deborah A. Goldspink, Benjamin G. Challis, Pierre Larraufie, Maria A T Groves, Fiona M. Gribble, Frank Reimann, Franco Ferraro, Stephen J. Middleton, Juraj Rievaj, Richard H. Hardwick, Jennifer L. Percival-Alwyn, Tamana Darwish, Stephen O'Rahilly

المساهمون: Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge [UK] (CAM), O’Rahilly, Stephen [0000-0003-2199-4449], Reimann, Frank [0000-0001-9399-6377], Apollo - University of Cambridge Repository, O'Rahilly, Stephen [0000-0003-2199-4449]

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-52049-0⟩

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Guanylin, lcsh:Medicine, 96/31, Article, 692/4020/198, 38/91, 96/95, Gastrointestinal Hormones, 03 medical and health sciences, symbols.namesake, 0302 clinical medicine, 692/163/2778, Organoid, medicine, Humans, Secretion, Intestinal Mucosa, Protein Precursors, Natriuretic Peptides, lcsh:Science, 14/35, Multidisciplinary, Ussing chamber, Chemistry, 82/58, lcsh:R, 64/110, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Golgi apparatus, Small intestine, 3. Good health, Cell biology, Transplantation, 030104 developmental biology, medicine.anatomical_structure, Gene Expression Regulation, Preclinical research, 030220 oncology & carcinogenesis, 14/63, symbols, lcsh:Q, 82/1

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d3c9a4afb8d35913618034046ac232
http://link.springer.com/article/10.1038/s41598-019-52049-0

المؤلفون: Liang, Huan-Chang, Costanza, Mariantonia, Prutsch, Nicole, Zimmerman, Mark W., Gurnhofer, Elisabeth, Montes-Mojarro, Ivonne A., Abraham, Brian J., Prokoph, Nina, Stoiber, Stefan, Tangermann, Simone, Lobello, Cosimo, Oppelt, Jan, Anagnostopoulos, Ioannis, Hielscher, Thomas, Pervez, Shahid, Klapper, Wolfram, Zammarchi, Francesca, Silva, Daniel-Adriano, Garcia, K. Christopher, Baker, David, Janz, Martin, Schleussner, Nikolai, Fend, Falko, Pospíšilová, Šárka, Janiková, Andrea, Wallwitz, Jacqueline, Stoiber, Dagmar, Simonitsch-Klupp, Ingrid, Cerroni, Lorenzo, Pileri, Stefano, de Leval, Laurence, Sibon, David, Fataccioli, Virginie, Gaulard, Philippe, Assaf, Chalid, Knörr, Fabian, Damm-Welk, Christine, Woessmann, Wilhelm, Turner, Suzanne D., Look, A. Thomas, Mathas, Stephan, Kenner, Lukas, Merkel, Olaf

المساهمون: Liang, Huan-Chang [0000-0003-2612-3714], Costanza, Mariantonia [0000-0002-8959-1083], Zimmerman, Mark W. [0000-0003-2489-3889], Montes-Mojarro, Ivonne A. [0000-0003-0636-7623], Abraham, Brian J. [0000-0001-8085-3027], Prokoph, Nina [0000-0002-6429-9895], Stoiber, Stefan [0000-0003-3293-867X], Oppelt, Jan [0000-0002-3076-4840], Klapper, Wolfram [0000-0001-7208-4117], Silva, Daniel-Adriano [0000-0002-3195-9009], Garcia, K. Christopher [0000-0001-9273-0278], Baker, David [0000-0001-7896-6217], Janz, Martin [0000-0002-1127-0044], Fend, Falko [0000-0002-5496-293X], de Leval, Laurence [0000-0003-3994-516X], Turner, Suzanne D. [0000-0002-8439-4507], Look, A. Thomas [0000-0001-7851-8617], Mathas, Stephan [0000-0001-9626-1413], Kenner, Lukas [0000-0003-2184-1338], Merkel, Olaf [0000-0001-5089-344X], Apollo - University of Cambridge Repository, Zimmerman, Mark W [0000-0003-2489-3889], Montes-Mojarro, Ivonne A [0000-0003-0636-7623], Abraham, Brian J [0000-0001-8085-3027], Garcia, K Christopher [0000-0001-9273-0278], Turner, Suzanne D [0000-0002-8439-4507], Look, A Thomas [0000-0001-7851-8617]

المصدر: Nature communications, vol. 12, no. 1, pp. 5577
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: CRISPR-Cas9 genome editing, Cancer Research, Immunoconjugates, Cell Survival, Science, Ki-1 Antigen, Regulatory Sequences, Nucleic Acid, 631/67/1990/291/1621/1916, 38/91, 96/95, Mice, Cell Line, Tumor, hemic and lymphatic diseases, Animals, Humans, Cell Proliferation, Interleukin-15, High-throughput screening, Interleukin-2 Receptor alpha Subunit, article, Receptors, Interleukin-2, Basic-Leucine Zipper Transcription Factors/genetics, Basic-Leucine Zipper Transcription Factors/metabolism, Cell Proliferation/drug effects, Cell Survival/drug effects, Gene Expression Regulation, Neoplastic, Immunoconjugates/pharmacology, Interleukin-15/pharmacology, Interleukin-2/pharmacology, Interleukin-2 Receptor alpha Subunit/genetics, Interleukin-2 Receptor alpha Subunit/immunology, Interleukin-2 Receptor alpha Subunit/metabolism, Ki-1 Antigen/genetics, Ki-1 Antigen/metabolism, Lymphoma, Large-Cell, Anaplastic/drug therapy, Lymphoma, Large-Cell, Anaplastic/genetics, Lymphoma, Large-Cell, Anaplastic/metabolism, Lymphoma, Large-Cell, Anaplastic/pathology, Receptors, Interleukin-2/genetics, Receptors, Interleukin-2/immunology, Receptors, Interleukin-2/metabolism, Repressor Proteins/genetics, Repressor Proteins/metabolism, Signal Transduction/drug effects, Xenograft Model Antitumor Assays, 45/15, 96/21, Repressor Proteins, 631/337/4041/3196, Mechanisms of disease, Basic-Leucine Zipper Transcription Factors, Interleukin-2, Lymphoma, Large-Cell, Anaplastic, T-cell lymphoma, 631/1647/2163, 631/80/304, 82/51, Signal Transduction

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https://www.repository.cam.ac.uk/handle/1810/328381

المؤلفون: Novoyatleva, Tatyana, Rai, Nabham, Kojonazarov, Baktybek, Veeroju, Swathi, Ben-Batalla, Isabel, Caruso, Paola, Shihan, Mazen, Presser, Nadine, Götz, Elsa, Lepper, Carina, Herpel, Sebastian, Manaud, Grégoire, Perros, Frédéric, Gall, Henning, Ghofrani, Hossein Ardeschir, Weissmann, Norbert, Grimminger, Friedrich, Wharton, John, Wilkins, Martin, Upton, Paul D, Loges, Sonja, Morrell, Nicholas W, Seeger, Werner, Schermuly, Ralph T

المساهمون: Novoyatleva, Tatyana [0000-0002-3367-9940], Caruso, Paola [0000-0002-3071-1917], Perros, Frédéric [0000-0001-7730-2427], Gall, Henning [0000-0001-7016-7373], Ghofrani, Hossein Ardeschir [0000-0002-2029-4419], Grimminger, Friedrich [0000-0001-8725-6276], Wharton, John [0000-0001-8110-2575], Wilkins, Martin [0000-0003-3926-1171], Upton, Paul D. [0000-0003-2716-4921], Morrell, Nicholas W. [0000-0001-5700-9792], Seeger, Werner [0000-0003-1946-0894], Schermuly, Ralph T. [0000-0002-5167-6970], Apollo - University of Cambridge Repository, Upton, Paul D [0000-0003-2716-4921], Morrell, Nicholas W [0000-0001-5700-9792], Schermuly, Ralph T [0000-0002-5167-6970], Upton, Paul [0000-0003-2716-4921], Morrell, Nicholas [0000-0001-5700-9792]

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology

مصطلحات موضوعية: Male, 631/80/82/23, Indoles, QH301-705.5, 631/443/592/1540, Apoptosis, Angiogenesis Inhibitors, Bone Morphogenetic Protein Receptors, Type II, Rats, Inbred WKY, 96/95, Rats, Sprague-Dawley, 13/2, Animals, Pyrroles, Biology (General), 38/109, Pulmonary Arterial Hypertension, Monocrotaline, article, Growth factor signalling, Receptor Protein-Tyrosine Kinases, Cardiac hypertrophy, Gene Expression Regulation, 14/63, 13/51, 38/77, 631/80/86/2368

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المؤلفون: Nick D. Bergkamp, Raimond Heukers, Eleanor Y. Lim, John Sinclair, Ian J. Groves, Elizabeth G. Elder, Mark R. Wills, Martine J. Smit, Timo W.M. De Groof

المساهمون: De Groof, Timo WM [0000-0001-6918-2955], Elder, Elizabeth G [0000-0003-1615-2642], Heukers, Raimond [0000-0003-4498-7751], Groves, Ian J [0000-0001-8882-6701], Smit, Martine J [0000-0003-2713-0238], Apollo - University of Cambridge Repository, De Groof, Timo W M [0000-0001-6918-2955], De Groof, Timo W. M. [0000-0001-6918-2955], Elder, Elizabeth G. [0000-0003-1615-2642], Groves, Ian J. [0000-0001-8882-6701], Smit, Martine J. [0000-0003-2713-0238], Supporting clinical sciences, Medicinal chemistry, AIMMS

المصدر: Nature Communications
De Groof, T W M, Elder, E G, Lim, E Y, Heukers, R, Bergkamp, N D, Groves, I J, Wills, M, Sinclair, J H & Smit, M J 2021, ' Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies ', Nature Communications, vol. 12, 4436, pp. 1-11 . https://doi.org/10.1038/s41467-021-24608-5
Nature Communications, 12:4436, 1-11. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: 0301 basic medicine, Human cytomegalovirus, viruses, 631/326/596, 96, Lipopolysaccharide Receptors, General Physics and Astronomy, Cytomegalovirus, Gene Expression, 639/925/352/152, Monocytes, 0302 clinical medicine, Cytotoxic T cell, Cells, Cultured, Multidisciplinary, article, virus diseases, food and beverages, humanities, Virus Latency, medicine.anatomical_structure, 030220 oncology & carcinogenesis, 38/35, Cytomegalovirus Infections, 38/77, Receptors, Chemokine, Stem cell, Infection, 82/1, Signal Transduction, Science, T cell, 13/106, Biology, General Biochemistry, Genetics and Molecular Biology, Virus, 96/95, 03 medical and health sciences, Viral Proteins, SDG 3 - Good Health and Well-being, Virology, medicine, Humans, Genes, Immediate-Early, Innate immune system, 692/420/254, fungi, General Chemistry, biochemical phenomena, metabolism, and nutrition, Single-Domain Antibodies, medicine.disease, 030104 developmental biology, Viral replication, Viral Receptor, Drug delivery, Virus Activation, T-Lymphocytes, Cytotoxic

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https://www.repository.cam.ac.uk/handle/1810/325364

المؤلفون: Matthew Harris, Davide Gianni, David R. Poyner, Tessa de Vries, Niamh Mullooly, Antoinette MaassenVanDenBrink, Dewi Safitri, Ashley J. Clark, Graham Ladds, Mark Wigglesworth

المساهمون: Wigglesworth, Mark [0000-0002-6421-3414], Ladds, Graham [0000-0001-7320-9612], Apollo - University of Cambridge Repository, Internal Medicine

المصدر: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology, 4(1):776. Springer Nature

مصطلحات موضوعية: 0301 basic medicine, Agonist, Calcitonin, medicine.drug_class, QH301-705.5, 45/41, Calcitonin Gene-Related Peptide, Peptide Hormones, Medicine (miscellaneous), Endogeny, 13/106, Calcitonin gene-related peptide, General Biochemistry, Genetics and Molecular Biology, 96/95, Receptors, G-Protein-Coupled, 03 medical and health sciences, Adrenomedullin, 0302 clinical medicine, Receptor pharmacology, 631/45/776/814, 38/23, medicine, Cyclic AMP, Humans, Biology (General), Receptors, Adrenomedullin, Receptor, Extracellular Signal-Regulated MAP Kinases, Cells, Cultured, G protein-coupled receptor, Chemistry, 631/92/436/2387, Calcitonin Receptor-Like Protein, article, Endothelial Cells, Cell biology, 030104 developmental biology, 13/95, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Endogenous agonist, Receptors, Calcitonin Gene-Related Peptide

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https://www.repository.cam.ac.uk/handle/1810/322519