المؤلفون: Rayane Rahmani, Naiomi Rambarack, Jaijeet Singh, Andrew Constanti, Afia B. Ali

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 19, p 14917 (2023)

مصطلحات موضوعية: Aβ amyloid-β, AD Alzheimer’s disease, App β-amyloid precursor protein, CA1 Cornu Ammonis, LEC Lateral enthorinal cortex, PRS Presubiculum, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/24/19/14917; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/8273ddd521bd48f49b840444698dc434

المؤلفون: Koch, Giacomo^{Aff3, Aff4}

المساهمون: Dell'Osso, Bernardo, editor^Aff1, Di Lorenzo, Giorgio, editor^Aff2

المصدر: Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences. :161-173

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المؤلفون: Yushiro Take, Yusaku Chikai, Keiya Shimamori, Masahiro Kuragano, Hiroki Kurita, Kiyotaka Tokuraku

المصدر: Biochemistry and Biophysics Reports, Vol 29, Iss, Pp 101189-(2022)
Biochemistry and Biophysics Reports

مصطلحات موضوعية: Aβ, amyloid β, hBMEC, human primary brain microvascular endothelial cell, Quantum dots, QH301-705.5, Biophysics, QD, quantum dot, Amyloid β, QD415-436, Biochemistry, Endothelial cell, Cerebral amyloid angiopathy, Biology (General), CAA, cerebral amyloid angiopathy, Research Article, Blood-brain barrier

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433e9cf4ef060261fbd3179385d37df8
http://www.sciencedirect.com/science/article/pii/S2405580821002831

المؤلفون: Karsten Vestergård, Jesper F. Havelund, Nils J. Færgeman, Shona Pedersen, Charlotte Held Gotfredsen, Raluca Maltesen, Søren Risom Kristensen, Jonas Ellegaard Nielsen

المصدر: Metabolism Open, Vol 12, Iss, Pp 100125-(2021)
Nielsen, J E, Maltesen, R G, Havelund, J F, Færgeman, N J, Gotfredsen, C H, Vestergård, K, Kristensen, S R & Pedersen, S 2021, ' Characterising Alzheimer's disease through integrative NMR-and LC-MS-based metabolomics ', Metabolism Open, vol. 12, 100125 . https://doi.org/10.1016/j.metop.2021.100125
Nielsen, J E, Maltesen, R G, Havelund, J F, Færgeman, N J, Gotfredsen, C H, Vestergård, K, Kristensen, S R & Pedersen, S 2021, ' Characterising Alzheimer's disease through integrative NMR-and LC-MS-based metabolomics ', Metabolism open, vol. 12, 100125 . https://doi.org/10.1016/j.metop.2021.100125
Metabolism Open

مصطلحات موضوعية: Purine, p-tau, Phospho-tau, Aβ, Amyloid-β, Physiology, Guanosine, QD415-436, Pharmacology, Biochemistry, ROC, Receiver operating characteristics, Nuclear magnetic resonance, MMSE, Mini-mental state examination, chemistry.chemical_compound, Metabolomics, Valine, medicine, Metabolites, sPLS-DA, Sparse partial least squared discriminant analysis, QP1-981, FAQ, Functional activities questionnaire, Inosine, AD, Alzheimer's Disease, EVs, Extracellular vesicles, chemistry.chemical_classification, CSF, Cerebrospinal fluid, PCA, Principal component analysis, Mass spectrometry, CNS, Central nervous system, business.industry, CV, Cross-validation, MCI, Mild cognitive impairment, General Medicine, Metabolism, Extracellular vesicles, AUC, Area under the curve, BBB, Blood-brain barrier, Extracellular vehicles, Fold change, t-tau, Total-tau, Amino acid, ACE, Addenbrooke's cognitive examination, Blood, chemistry, Alzheimer, FDR, False discovery rate, business, BCAA, Branched-chain amino acid, Articles from the Clinical Metabolomics Special Issue, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36710fd7cf80b8c201090924500ca109
http://www.sciencedirect.com/science/article/pii/S2589936821000499

المؤلفون: Xiaoyue Zhu, Annemieke J.M. Rozemuller, Baayla D.C. Boon, Steven O. Smith, Judianne Davis, William E. Van Nostrand, Brandon A. Irizarry

المساهمون: Pathology, Amsterdam Neuroscience - Neurodegeneration

المصدر: Journal of Biological Chemistry, 297(5):101259. American Society for Biochemistry and Molecular Biology Inc.
Irizarry, B A, Davis, J, Zhu, X, Boon, B D C, Rozemuller, A J M, van Nostrand, W E & Smith, S O 2021, ' Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils ', Journal of Biological Chemistry, vol. 297, no. 5, 101259 . https://doi.org/10.1016/j.jbc.2021.101259
The Journal of Biological Chemistry

مصطلحات موضوعية: Male, Aβ, amyloid β, cryo-EM, electron cryo-microscopy, Amyloid, Mutation, Missense, macromolecular substances, amyloid-β, Fibril, Antiparallel (biochemistry), Biochemistry, polymorphism, Alzheimer Disease, APP, amyloid precursor protein, ATR, attenuated total reflectance, medicine, Amyloid precursor protein, Humans, CAA, cerebral amyloid angiopathy, TEM, transmission electron microscopy, Nuclear Magnetic Resonance, Biomolecular, cerebral amyloid angiopathy, Molecular Biology, Vascular tissue, Aged, Laser capture microdissection, Amyloid beta-Peptides, biology, Chemistry, DARR, dipolar-assisted rotational resonance, CAA/s, sporadic cerebral amyloid angiopathy, Brain, ELISA, enzyme-linked immunosorbent assay, Cell Biology, Human brain, Alzheimer's disease, MAS, magic angle spinning, medicine.disease, Peptide Fragments, TBS, Tris-HCl buffered saline, FTIR, Fourier transform infrared, medicine.anatomical_structure, Amino Acid Substitution, Biophysics, biology.protein, antiparallel fibrils, AD, Alzheimer's disease, Cerebral amyloid angiopathy, LCM, laser capture microdissection, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd3f4ab805e95733c6739472c1ffb5e
https://research.vumc.nl/en/publications/26e2698a-be3a-4407-96df-0100a196db73

المؤلفون: Nicolas Joubert, Aubin Pitiot, Nathalie Heuzé-Vourc'h, Matthieu Gracia, Caroline Denevault-Sabourin, Timothée Blin, Thomas Sécher, Jean-Pierre Pouget, Juliette Lamamy, Sophie Poty, Valérie Gouilleux-Gruart, Débora Lanznaster, Yara Al Ojaimi

المساهمون: Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Groupe innovation et ciblage cellulaire (GICC), EA 7501 [2018-...] (GICC EA 7501), Université de Tours (UT), Institut de Radiobiologie Cellulaire et Moléculaire (IRCM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut du Cancer de Montpellier (ICM), Le Pennec, Deborah, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours (UT)

المصدر: Pharmacology and Therapeutics
Pharmacology and Therapeutics, 2021, pp.108022. ⟨10.1016/j.pharmthera.2021.108022⟩
Pharmacology & Therapeutics
Pharmacology and Therapeutics, Elsevier, 2021, pp.108022. ⟨10.1016/j.pharmthera.2021.108022⟩

مصطلحات موضوعية: pI, isoelectric point, EU, European union, TNF, tumour necrosis factor, US, United States, Recombinant antibodies, Medicine, Pharmacology (medical), HER2, human epidermal growth factor receptor 2, Patient comfort, Target antigen, FcRn, neonatal Fc receptor, biology, GI, gastrointestinal, VEGF, vascular endothelial growth factor, ECM, extracellular matrix, IFP, interstitial fluid pressure, MMP, matrix metalloproteinase, Therapeutic strategies, Fab, fragment antigen-binding, RNA, Viral, AD, Alzheimer's disease, Antibody, 2019-20 coronavirus outbreak, medicine.medical_specialty, BBB, blood-brain barrier, IA, intra-articular, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), IgG, immunoglobulin G, CNS, central nervous system, ADC, antibody-drug conjugate, PK, pharmacokinetic, Antibodies, Therapeutic index, PD, pharmacodynamics, Biological barriers, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, IVIg, intravenous immunoglobulin, Humans, Immunologic Factors, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, mAb, monoclonal antibody, Intensive care medicine, Pandemics, Pharmacology, business.industry, SARS-CoV-2, IdeS, bacteria secreted proteases, scFv, single-chain variable fragment, Pathological barriers, Aβ, amyloid-β, FDA, Food and Drug Administration, COVID-19 Drug Treatment, Invited Article, biology.protein, Fc, fragment crystallizable, business, Site of action

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ee69ea99fbe731deecbad7ca213160
https://hal.science/hal-03531953

المؤلفون: Pedro Ozorio Brum, Flávio Gabriel Carazza Kessler, Alana Castro Panzenhagen, Hugo C. Castro-Faria-Neto, Marlene Campos Soares, Giuliana Viegas Schirato, Walter César Góes Valente, Bogar Omar Araújo Montoya, José Cláudio Fonseca Moreira, Patrícia A. Reis, Daniel Pens Gelain, Lin Kooi Ong, Floriano P. Silva, Juciano Gasparotto, Daniel Oppermann Peixoto, Felipe Dal-Pizzol, Mario Roberto Senger, Emilio Telles de Sá Moreira

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, antioxidant, Morris water navigation task, Siderophores, Disease, Biochemistry, CSF, cerebrospinal fluid, Praziquantel, neuroinflammation, Mice, Morris Water Maze Test, DEG, differentially expressed gene, Medicine, neurological disease, Anthelmintics, biology, amyloid-beta (Aβ), neurodegeneration, Neurodegenerative Diseases, Schistosoma mansoni, Free Radical Scavengers, Microglia, medicine.drug, Research Article, Aβ, amyloid-β peptide, PZQ, praziquantel, Schistosomiasis, Tau phosphorylation, Deferoxamine, CNS, central nervous system, schistosomiasis, 4-HNE, 4-hydroxynonenal, SOD, superoxide dismutase, Animals, Molecular Biology, Neuroinflammation, Schistosoma, business.industry, tauopathy, GFAP, glial fibrillary acidic protein, Tropical disease, Cell Biology, PI, pixel intensity, medicine.disease, biology.organism_classification, Schistosomiasis mansoni, Acetylcysteine, Disease Models, Animal, Astrocytes, Immunology, Def, deferoxamine, NAC, N-acetyl-cysteine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf79d482bbf1969a5c99fa929529ec2
http://europepmc.org/articles/PMC8361297

المؤلفون: Wen Yao, Luciano D'Adamio, Tao Yin, Kelly A Norris

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Male, imBRI2, immature BRI2, amyloid precursor protein, Deafness, Biochemistry, Synaptic Transmission, Amyloid beta-Protein Precursor, PPF, paired-pulse facilitation, FBD, familial British dementia, Postsynaptic potential, Amyloid precursor protein, rat, education.field_of_study, Neurodegeneration, neurodegeneration, ITM2b, integral membrane protein 2B, NMDAR, N-methyl-d-aspartic acid, Receptors, Glutamate, Rs, series resistance, Excitatory postsynaptic potential, amyloid β, AMPAR, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor, Female, AD, Alzheimer's disease, Research Article, Aβ, amyloid β, Cerebellar Ataxia, integral membrane protein 2B, Neural facilitation, Presynaptic Terminals, glutamate, Biology, Cataract, APP, amyloid-β precursor protein, Glutamatergic, BRI2, Alzheimer Disease, Memory, medicine, KI, knock in, Integral membrane protein 2B, Animals, mEPSC, miniature excitatory postsynaptic current, Excitatory Amino Acid Agents, mBRI2, mature BRI2, education, Molecular Biology, NFT, neurofibrillary tangle, Adaptor Proteins, Signal Transducing, Amyloid beta-Peptides, synaptic plasticity, animal model, Membrane Proteins, Cell Biology, familial Danish dementia, medicine.disease, Pr, probability of release, Rats, Disease Models, Animal, SC, Schaeffer-collateral, Synaptic plasticity, Synapses, biology.protein, ACSF, artificial cerebrospinal fluid, Dementia, ISI, interstimulus interval, Neuroscience, FDD, familial Danish dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e551c51b462662a8e05481a6c8b948
https://pubmed.ncbi.nlm.nih.gov/34416235