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المؤلفون: Alexandria M. Doerfler, Christine Beeton, Kelsey E Jarrett, Ang Li, Marco De Giorgi, Mark R. Tanner, William R. Lagor, Timothy H. Davis, Ciaran M. Lee, Gang Bao, Ayrea Hurley

المصدر: Molecular Therapy

مصطلحات موضوعية: AAV-CRISPR, Genetic enhancement, pre-existing immunity, adeno-associated virus, Biology, liver, medicine.disease_cause, Genome, immune response, 03 medical and health sciences, 0302 clinical medicine, Immune system, Genome editing, Drug Discovery, Genetics, medicine, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Gene and molecular therapy, Molecular Biology, Adeno-associated virus, 030304 developmental biology, Gene Editing, Pharmacology, 0303 health sciences, Cas9, somatic genome editing, SaCas9, gene therapy, Virology, Liver regeneration, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, hepatocytes, CRISPR-Cas Systems, CD8+ T cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a03e82596d4aabb913f05e713551232
https://doi.org/10.1016/j.ymthe.2020.04.017

المؤلفون: Alexandria M. Doerfler, Weiqi Lu, Ang Li, Ciaran M. Lee, Harshavardhan Deshmukh, William R. Lagor, Karol S. Balderrama, Anirban Ray, Gang Bao, Ayrea Hurley, Marco De Giorgi, Kelsey E Jarrett

المصدر: Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 12, Iss, Pp 111-122 (2019)

مصطلحات موضوعية: in vivo delivery, AAV-CRISPR, lcsh:QH426-470, viruses, Mutagenesis (molecular biology technique), Computational biology, adeno-associated virus, Biology, medicine.disease_cause, liver, Genome, Article, 03 medical and health sciences, 0302 clinical medicine, Genome editing, Genetics, medicine, CRISPR, Guide RNA, lcsh:QH573-671, Molecular Biology, Gene, Adeno-associated virus, CRISPR/Cas9, 030304 developmental biology, 0303 health sciences, lcsh:Cytology, Cas9, somatic genome editing, AAV, gene therapy, lcsh:Genetics, self-deleting, Molecular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd77133a1d7658443ad35fe298b0f7d
http://europepmc.org/articles/PMC6313841

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لا يتم عرض هذه النتيجة على الضيوف.
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لا يتم عرض هذه النتيجة على الضيوف.
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المؤلفون: Li A; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Lee CM; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Hurley AE; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA., Jarrett KE; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.; Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., De Giorgi M; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA., Lu W; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Balderrama KS; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA., Doerfler AM; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA., Deshmukh H; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Ray A; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Bao G; Department of Bioengineering, Rice University, Houston, TX 77030, USA., Lagor WR; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.; Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.

المصدر: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2018 Dec 06; Vol. 12, pp. 111-122. Date of Electronic Publication: 2018 Dec 06 (Print Publication: 2019).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE