المؤلفون: Lucía Prieto Santamaría, Alejandro Rodríguez-González, Marina Díaz Uzquiano, Esther Ugarte Carro, Yuliana Pérez Gallardo, Ernestina Menasalvas Ruiz

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4559-4573 (2021)

مصطلحات موضوعية: Computer science, Drug repurposing, ND, New Disease, SRD5A1, Steroid 5 Alpha-Reductase 1, DR, Drug Repurposing or Drug Repositioning, computer.software_genre, Biochemistry, AHR, Aryl Hydrocarbon Receptor, FCGR3B, Fc Fragment Of IgG Receptor IIIb, Structural Biology, DISNET knowledge base, PTGS2, Prostaglandin-endoperoxidase synthase 2, Disease understanding, UMLS, Unified Medical Language System, Repurposing, ESR2, Estrogen Receptor 2, GDA, Gene Disease Association, OD, Original Disease, FCGR3A, Fc Fragment Of IgG Receptor IIIa, TNFα, Tumour Necrosis Factor alpha, Computer Science Applications, Drug-disease validation, Drug repositioning, Drug development, Data integration, SM, Supplementary Material, Research Article, SRD5A2, Steroid 5 Alpha-Reductase 2, Biotechnology, CUI, Concept Unique Identifier, Process (engineering), DRD3, Dopamine Receptor D3, Biophysics, Data-driven, KDR, Kinase insert Domain Receptor, NLM, National Library of Medicine, Biomedical data, ComputerApplications_MISCELLANEOUS, Genetics, ALK, Anaplastic Lymphoma Kinase, ESR1, Estrogen Receptor 1, ComputingMethodologies_COMPUTERGRAPHICS, LTα, Lymphotoxin alpha, COX-2, Cyclooxygenase 2, MeSH-PA, Medical Subject Headings – Pharmacological Action, Significant difference, Data science, ICD-10-CM, International Classification of Diseases, 10th revision, Clinical Modification, ComputingMethodologies_PATTERNRECOGNITION, API, Application Programming Interface, ID, Identifier, ACE, Angiotensin I Converting Enzyme, CMap, Connectivity Map, FCGR2A, Fc Fragment Of IgG Receptor IIa, computer, TP248.13-248.65

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0161caf3f0dc9bcf4a7eacdbdeed248
https://doi.org/10.1016/j.csbj.2021.08.003

المؤلفون: Anuar Salazar-Gómez, Saudy Saret Pablo-Pérez, M. Elena Vargas-Dı́az, Julio C. Ontiveros-Rodríguez, Leticia Garduño-Siciliano

المصدر: South African Journal of Botany

مصطلحات موضوعية: IL-1β, interleukin 1 beta, 0106 biological sciences, GSH, reduced glutathione, Structural diversity, Review, Plant Science, 01 natural sciences, G6Pase, glucose-6-phosphatase, Hypolipidemic, chemistry.chemical_compound, Broad spectrum, IR, insulin resistance, TBARS, thiobarbituric acid reactive substances, FFA, free fatty acids, TNF-α, tumor necrosis factor alpha, AMPK, activated protein kinase, Medicinal plants, STAT1, signal transducer and activator of transcription 1, NF-κB, nuclear factor kappa B, GPx, glutathione peroxidase, SLns, sesquiterpene lactones, JNK, c-Jun N-terminal kinases, Biological activity, TG, triglycerides, Metabolic syndrome, IL-6, interleukin 6, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, MetS, metabolic syndrome, Sesquiterpene lactones, COX-2, cyclooxygenase 2, GK, glucokinase, MCP-1, monocyte chemoattractant protein 1, Computational biology, CVD, cardiovascular disease, Biology, Sesquiterpene, STZ, streptozotocin, Tc total cholesterol, ROS, reactive oxygen species, SOD, superoxide dismutase, AT, adipose tissue, medicine, LDL-C, low-density lipoprotein-cholesterol, Beneficial effects, FN, fibronectin, TLRs, Toll-like receptor, NO, nitric oxide, IFN-γ, interferon gamma, HDL-C, high-density lipoproteins-cholesterol, VLDL, very-low-density lipoprotein, T2DM, type 2 diabetes mellitus, Hypoglycemic, medicine.disease, ACE, angiotensin I-converting enzyme, 0104 chemical sciences, APOC3, apolipoprotein C3, TC, total cholesterol, TGF-β1, transforming growth factor beta, 010404 medicinal & biomolecular chemistry, Antidiabetic, chemistry, MAPK, mitogen-activated protein kinases, CAT, catalase, 010606 plant biology & botany

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512583e8aceec7a8d3995bc13c6d8a6c
https://doi.org/10.1016/j.sajb.2020.08.020

المؤلفون: Takano, T.^Aff5

المساهمون: Siezen, R. J., editor^Aff1, Kok, J., editor^Aff2, Abee, T., editor^Aff3, Schasfsma, G., editor^Aff4

المصدر: Lactic Acid Bacteria: Genetics, Metabolism and Applications : Proceedings of the seventh Symposium on lactic acid bacteria: genetics, metabolism and applications, 1–5 September 2002, Egmond aan Zee, the Netherlands. :333-340

المؤلفون: Murat Oz, Nadine Kabbani, Dietrich E. Lorke

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: 0301 basic medicine, MAP, mitogen-activated protein, Angiotensin-Converting Enzyme Inhibitors, Disease, medicine.disease_cause, Bioinformatics, Renin-Angiotensin System, ACE, Angiotensin I converting enzyme, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, S protein, spike protein, Pharmacology (medical), ACE-Inh., Angiotensin I converting enzyme inhibitor, NOS, nitric oxide synthase, T2DM, Type 2 diabetes mellitus, Coronavirus, Ang-II, Angiotensin II, IBD, inflammatory bowel disease, DABK, [des-Arg9]-bradykinin, ADAM17, A Disintegrin And Metalloprotease 17, COPD, chronic obstructive lung disease, 030220 oncology & carcinogenesis, Angiotensin-converting enzyme 2, AT1-R, Angiotensin II type 1-receptor, Steroids, Angiotensin-Converting Enzyme 2, BK, bradykinin, TCM, Traditional Chinese medicine, MRB, Mineralocorticoid receptor blocker, HS, heparan sulfate, 25HC, 25-hydroxycholesterol, COVID-19, Coronavirus disease-2019, Article, SARS-CoV, Severe acute respiratory syndrome coronavirus, CH25H, cholesterol-25-hydroxylase, NSAID, Non-steroid anti-inflammatory drug, ARB, Angiotensin II type 1-receptor blocker, SIRT1, Sirtuin 1, 03 medical and health sciences, Downregulation and upregulation, Viral entry, Diabetes mellitus, ARDS, Acute respiratory distress syndrome, Renin–angiotensin system, medicine, Animals, Humans, HSPG, heparan sulfate proteoglycan, UFH, unfractionated heparin, TMPRSS2, Transmembrane protease, serine 2, CCB, Calcium channel blockers, Pharmacology, SARS-CoV-2, βARB, β-adrenergic receptor blockers, business.industry, MERS, Middle East respiratory syndrome, TNF, Tumor necrosis factor, COVID-19, medicine.disease, SH, spontaneously hypertensive, COVID-19 Drug Treatment, COX, cyclooxygenase, AMPK, AMP-activated protein kinase, 030104 developmental biology, Heart failure, RAS, Renin-angiotensin system, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9934ef0c6702914904ddd32cd943ffca

المؤلفون: Anthony P. Davenport, H. Llewelyn Roderick, Emma L. Robinson, Kanar Alkass, Janet J. Maguire, Olaf Bergmann

المساهمون: Cardiologie, RS: Carim - H02 Cardiomyopathy, Maguire, Janet [0000-0002-9254-7040], Davenport, Anthony [0000-0002-2096-3117], Apollo - University of Cambridge Repository

المصدر: Journal of Molecular and Cellular Cardiology, 147, 88-91. ELSEVIER SCI LTD
Journal of Molecular and Cellular Cardiology

مصطلحات موضوعية: 0301 basic medicine, Aging, Cathepsin L, ACE, angiotensin I converting enzyme, Disease, 030204 cardiovascular system & hematology, BDKRB2, bradykinin receptor B2, ComputingMethodologies_ARTIFICIALINTELLIGENCE, Cathepsin B, Angiotensin, 0302 clinical medicine, Interferon, MAS1, MAS1 proto-oncogene G protein-coupled receptor, Medicine, TMPRSS11D, transmembrane protease serine 11D, Myocytes, Cardiac, TMPRSS2, transmembrane protease serine 2, Young adult, Furin, IFNAR1, interferon (alpha beta and omega) receptor 1, biology, Serine Endopeptidases, Interleukin, AGTR1, angiotensin II receptor type 1, Apelin, BDKRB1, bradykinin receptor B1, apelin, Interferon gamma receptor 1, TMPRSS11E, transmembrane protease serine 11E, Angiotensin-Converting Enzyme 2, Cardiology and Cardiovascular Medicine, Coronavirus Infections, medicine.drug, Angiotensins, InformationSystems_INFORMATIONSTORAGEANDRETRIEVAL, Pneumonia, Viral, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, RNA-sequencing, CTSB, cathepsin B, Virus Attachment, APLNR, apelin receptor, IRF1, interferon regulatory factor 1 (regulates transcription of interferons), Peptidyl-Dipeptidase A, Bradykinin, FURIN, furin (paired basic amino acid cleaving enzyme), TMPRSS2, Article, 03 medical and health sciences, Betacoronavirus, Downregulation and upregulation, Humans, ADAM17, ADAM metallopeptidase domain 17, IL6R, interleukin 6 receptor, Molecular Biology, Pandemics, Gene, ComputingMethodologies_COMPUTERGRAPHICS, SLC6A19, solute carrier family 6 (neutral amino acid transporter) member 19 (aka B0AT1), SARS-CoV-2, business.industry, Myocardium, human cardiomyocytes, IFNAR2, interferon (alpha beta and omega) receptor 2 (IFNAR1and 2 form chains for interferons alpha and beta), COVID-19, Virus Internalization, angiotensin, CTSL, cathepsin L, ComputingMethodologies_PATTERNRECOGNITION, 030104 developmental biology, Immunology, biology.protein, IFNGR1, Interferon gamma receptor 1, Human cardiomyocytes, ACE2, angiotensin I converting enzyme 2, business

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f95f476673d68f64444c4caae84f8cf
https://doi.org/10.1101/2020.07.07.191429

المؤلفون: Vimal Kumar, Mohammad Yaseen Khan

المصدر: Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine, Vol 9, Iss 1, Pp 73-84 (2019)

مصطلحات موضوعية: BP, blood pressure, mL, milli litre, HHL, hippury-l-histidyl-l-leucine, UV, ultra violet, 0211 other engineering and technologies, lcsh:Medicine, IC50, half maximal inhibitory concentration, M, Molar, 02 engineering and technology, ng, nano gram, mg, milligram, 01 natural sciences, DMSO, dimethyl sulphoxide, chemistry.chemical_compound, QEs, quercetin equivalents, Cassia, 021105 building & construction, Km, Michaelis-Menten constant, Gallic acid, BSC, benzene sulphonyl chloride, n-BuOH, n-butanol, Traditional medicine, biology, Chemistry, CH2Cl2, dichloromethane, TCA, Trichloroacetic acid, Lineweaver-burk plots, Mu, Milli units, Original Article, Quercetin, Angiotensin converting enzyme, EtOH, ethanol, HA, hippuric acid, Embelia ribes, Vmax, Maximum velocity, Zn2+, Zinc ion, Mode of inhibition, TFA, trifluoroacetic acid, EtOAc, Ethyl acetate, GAEs, gallic acid equivalents, IC50, Coscinium fenestratum, ZnCl2, Zinc chloride, lcsh:R, Cynara scolymus, Enzyme kinetics, Angiotensin-converting enzyme, RAS, renin-angiotensin system, biology.organism_classification, 0104 chemical sciences, Mm, Milli mole, 010404 medicinal & biomolecular chemistry, HCl, Hydrochloric acid, Complementary and alternative medicine, biology.protein, ACE, Angiotensin I Converting Enzyme, BAPNA, a-N-benzoyl-dl-arginine-Pnitroanilide HCl, BSA, bovine serum albumin, MeOH, methanol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9f0d51908b7221eb06267443bab4e4
http://europepmc.org/articles/PMC6335474

المؤلفون: Takano, Dr. T.

المصدر: Antonie van Leeuwenhoek: International Journal of General and Molecular Microbiology. August 2002 82(1-4):333-340

المؤلفون: Hisham R. Ibrahim, Ahmed S. Ahmed, Takeshi Miyata

المصدر: Journal of Advanced Research
Journal of Advanced Research, Vol 8, Iss 1, Pp 63-71 (2017)

مصطلحات موضوعية: Goat milk, P-GCP, pepsin digested-GCP, medicine.drug_class, HL, histidyl-leucine, Angiotensin I-converting enzyme (ACE), Peptide, HHL, hippuryl-histidyl-leucine, MALDI-TOF/MS, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, 01 natural sciences, Hydrolysate, 0404 agricultural biotechnology, Whey, medicine, TNP-, 2,4,6-trinitrophenyl, lcsh:Science (General), General, Antihypertensive drug, GCP, goat casein proteins, Bioactive peptides, ComputingMethodologies_COMPUTERGRAPHICS, chemistry.chemical_classification, lcsh:R5-920, TNBS, 2,4,6-trinitrobenzene sulfonate, Multidisciplinary, P-GWP, pepsin digested-GWP, biology, 010405 organic chemistry, Caseins, food and beverages, Captopril, Angiotensin-converting enzyme, 04 agricultural and veterinary sciences, ACE, angiotensin I-converting enzyme, Anti-hypertension, 040401 food science, Angiotensin II, GWP, goat whey proteins, 0104 chemical sciences, Enzyme, Biochemistry, chemistry, biology.protein, Original Article, lcsh:Medicine (General), Digestion, HA, hippuric acid, lcsh:Q1-390, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec90a57cdb8ec3a9d087b0e963ac4c4b
https://doi.org/10.1016/j.jare.2016.12.002

المؤلفون: Giuseppina Colonna-Romano, Calogero Caruso, Letizia Scola, Domenico Lio, Rosa Maria Giarratana, Carmela Rita Balistreri, Giuseppina Candore

المساهمون: Lio D., Scola L., Giarratana R.M., Candore G., Colonna-Romano G., Caruso C., Balistreri C.R.

المصدر: Ageing Research Reviews

مصطلحات موضوعية: Male, Aging, ssRNA, single-stranded RNA, RFLP, restriction fragment length polymorphism, HSPs, heat shock proteins, Review, PTMs, post-translational modifications, Severe Acute Respiratory Syndrome, Biochemistry, HIV-1, human immunodeficiency virus-1, TNF-α, tumor necrosis factor-α, EC, endothelial cells, 0302 clinical medicine, FluAV, influenza A virus, I, insertion, Medicine, IFN-γ, interferon-γ, DIC, disseminated intravascular coagulation, PCR, Polymerase Chain Reaction, media_common, Aged, 80 and over, Longevity, RBD, receptor-binding domain, Neurology, Longevity model, MI, myocardial infarction, NK, natural killer, hPIV2, human parainfluenza virus type 2, media_common.quotation_subject, Researching genetic basis of resistance and potential pharmacological targets, DBP, diastolic blood pressure, NF-Kb, nuclear transcription factor kB, RANTES, regulated upon activation, normal T cell expressed and secreted, Mphi, human macrophages, 03 medical and health sciences, Cox 2, cyclooxygenase 2, ORF, open reading frame, PT, prothrombin time, Settore MED/05 - Patologia Clinica, Humans, Molecular Biology, Inflammatory genes, ARDS, acute respiratory distress syndrome, NO, nitric oxide, D, deletion, CpGIs, CpG islands, T2DM, type 2 diabetes mellitus, medicine.disease, FDP, fibrin degradation products, 030104 developmental biology, SARS CoV2, severe acute respiratory syndrome Coronavirus 2 virus, Immunology, BMI, body max index, Italian nonagenarians/centenarians, RSV, respiratory syncytial virus, Complication, 030217 neurology & neurosurgery, MAPK, mitogen-activated protein kinase, IP-10, IFN-γ -Inducible Protein 104, 0301 basic medicine, AT1R, activity of angiotensin 1 receptors, DCs, dentritic cells, SSCP, single strand conformation polymorphism, ACE/DD, polymorphism of the angiotensin converting enzyme, FGF21, fibroblast growth factor 21, TLR4, toll-like receptor 4, NAD, nicotinamide adenine dinucleotide, ACE, angiotensin-I converting enzyme, AT2R, activity of angiotensin 2 receptors, COVID-19, Coronavirus disease 2019, Respiratory distress, ACE2, angiotensin converting enzyme 2, MKP-1, mitogen-activated protein kinase phosphatase-1 (), PD, protease domain, SNP, single nucleotide polymorphism, EH, essential hypertension, TNFR, tumor necrosis factor receptor, INR, international normalized ratio of the prothrombin time, PAI-1, plasminogen activator inhibitor-1, Ang, angiotensin, LPS, lipopolysaccharide, MCP1, monocyte chemoattractant protein-1, medicine.symptom, aPTT, partial thromboplastin time, Biotechnology, DUSP1, dual specificity phosphatase 1, Coronavirus disease 2019 (COVID-19), PC, prostate cancer, RAS, renin-angiotensin aldosterone system, CCR5Δ32, genetic variant of chemokine receptor, COVID-19, Researching genetic basis of resistance and potential pharmacological targets, Italian nonagenarians/centenarians, Longevity model, Asymptomatic, SARS-1, severe acute respiratory syndrome virus 1, SIRT-1, Sirtuin 1, Th1, t-helper lymphocyte type 1, Immune system, ROS, reactive oxygen species, TGF-β, transforming growth factor beta, ET-1, endothelin-1, ComputingMethodologies_COMPUTERGRAPHICS, ADAM-17, metallopeptidase domain 17, business.industry, SARS-CoV-2, SBP, systolic blood pressure, COVID-19, HDACs, histone deacetylases, Comorbidity, Immune System, business, 5-LO, lipoxygenase 5

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4692d189085f46ab85ae71489ec5d0
http://europepmc.org/articles/PMC7885677

المؤلفون: Cuie Guang, Robert D. Phillips, Franco Milani, Bo Jiang

المصدر: Archives of Cardiovascular Diseases

مصطلحات موضوعية: Inhibiteur de l’enzyme de conversion II, ARB, AT1 receptor blocker, HEXXH, His-Glu-X-X-His, Protein Conformation, CoV, coronavirus, ACE2, Angiotensin-Converting Enzyme Inhibitors, Renin-Angiotensin System, Angiotensin, Récepteur de la prorénine, LH-RH, luteinizing hormone-releasing hormone, Renin, Ang I, angiotensin I, Receptor, AcSDKP, N-acetyl-Ser-Asp-Lys-Pro, (P)RR, (pro)renin receptor, chemistry.chemical_classification, AT1 receptor, angiotensin II receptor, type 1, General Medicine, cAMP, cyclic adenosine monophosphate, Angiotensine, Aβ, Alzheimer amyloid β-peptide, Angiotensin-converting enzyme 2, Angiotensin-Converting Enzyme 2, Cardiology and Cardiovascular Medicine, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, Proteases, medicine.medical_specialty, ACE, angiotensin-I-converting enzyme, Receptors, Cell Surface, Peptidyl-Dipeptidase A, XNT, 1-[(2-diethylamino)ethylamino]-4-(hydroxymethyl)-7-[(4-methylphenyl)sulphonyloxy]-9H-xanthene-9-one, Catalysis, Article, Proinflammatory cytokine, Inhibiteurs de l’enzyme de conversion, Structure-Activity Relationship, AGT, angiotensinogen, Internal medicine, Renin–angiotensin system, medicine, Animals, Humans, Rénine, SARS, severe acute respiratory syndrome, Antihypertensive Agents, ACE, Ang II, angiotensin II, Angiotensin II receptor type 1, business.industry, ACE2, angiotensin-I-converting enzyme 2, HRP, hand region peptide, RAS, renin-angiotensin system, Angiotensin II, Endocrinology, Enzyme, chemistry, sACE, somatic ACE, (Pro)renin receptor, business, SHR, spontaneously hypertensive rat, gACE, germinal ACE, TACE, tumour necrosis factor-alpha cleavage enzyme

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc261142323704b99c37791272ffd43