المؤلفون: El Gammal RN; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Elmansi H; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., El-Emam AA; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Belal F; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Hammouda MEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Horus University-Egypt (HUE), New Damietta, Egypt.

المصدر: Luminescence : the journal of biological and chemical luminescence [Luminescence] 2024 Jun; Vol. 39 (6), pp. e4792.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley & Sons Country of Publication: England NLM ID: 100889025 Publication Model: Print Cited Medium: Internet ISSN: 1522-7243 (Electronic) Linking ISSN: 15227235 NLM ISO Abbreviation: Luminescence Subsets: MEDLINE

مواضيع طبية MeSH: Pyrazines*/chemistry , Pyrazines*/metabolism , Amides*/chemistry , Amides*/metabolism , Adenine Nucleotides*/chemistry , Adenine Nucleotides*/metabolism , Antiviral Agents*/chemistry , Antiviral Agents*/pharmacology , Antiviral Agents*/metabolism , Thermodynamics*, Spectroscopy, Fourier Transform Infrared ; Spectrometry, Fluorescence ; Fluorescence Resonance Energy Transfer ; Spectrophotometry, Ultraviolet ; Binding Sites ; Adenine/chemistry ; Adenine/metabolism

المؤلفون: Choi Y; Department of Biomedical Science, Graduate School of Ajou University, Worldcup-ro 164, Yeoungtong-gu, Suwon-si 16499, South Korea. Electronic address: rkddpf1123@naver.com., Kim SH; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Worldcup-ro 164, Yeoungtong-gu, Suwon-si 16499, South Korea. Electronic address: oh4038@naver.com., Jun Shin S; Department of Biomedical Science, Graduate School of Ajou University, Worldcup-ro 164, Yeoungtong-gu, Suwon-si 16499, South Korea. Electronic address: 01075871087t@gmail.com., Park HS; Department of Biomedical Science, Graduate School of Ajou University, Worldcup-ro 164, Yeoungtong-gu, Suwon-si 16499, South Korea; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Worldcup-ro 164, Yeoungtong-gu, Suwon-si 16499, South Korea. Electronic address: hspark@ajou.ac.kr., Seob Shin Y; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Worldcup-ro 164, Yeoungtong-gu, Suwon-si 16499, South Korea. Electronic address: drsys93@naver.com.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 May 10; Vol. 132, pp. 111903. Date of Electronic Publication: 2024 Apr 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Adenine*/*analogs & derivatives, Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors , Asthma*/drug therapy , Asthma*/immunology , Mice, Inbred BALB C* , Piperidines*/therapeutic use , Piperidines*/pharmacology , Ovalbumin*/immunology , Disease Models, Animal* , Adenine*/therapeutic use , Adenine*/pharmacology , Immunoglobulin E*/blood , Immunoglobulin E*/immunology , Cytokines*/metabolism , Eosinophils*/immunology , Eosinophils*/drug effects , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/therapeutic use, Animals ; Mice ; Pyrimidines/therapeutic use ; Pyrimidines/pharmacology ; Female ; Pyrazoles/therapeutic use ; Pyrazoles/pharmacology ; Bronchoalveolar Lavage Fluid/cytology ; Bronchoalveolar Lavage Fluid/immunology ; Immunoglobulin G/blood ; Anti-Asthmatic Agents/therapeutic use ; Anti-Asthmatic Agents/pharmacology ; Cells, Cultured ; Humans ; Mast Cells/drug effects ; Mast Cells/immunology

المؤلفون: Shadman M; Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA, USA. mshadman@fredhutch.org., Tedeschi A; ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Mohseninejad L; BeiGene, Netherlands B.V., Schiphol, The Netherlands., Yang K; BeiGene USA Inc, San Mateo, CA, USA., Lamanna N; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Xu S; BeiGene (Beijing) Co. Ltd., Beijing, China., Cohen A; BeiGene USA Inc, San Mateo, CA, USA., Challagulla S; BeiGene USA Inc, San Mateo, CA, USA., Xue M; BeiGene USA Inc, San Mateo, CA, USA., Williams R; BeiGene USA Inc, San Mateo, CA, USA., O'Brien SM; Chao Family Comprehensive Cancer Center, University of California, Irvine, CA, USA., Brown JR; Dana-Farber Cancer Institute, Boston, MA, USA., Tam C; The Alfred Hospital and Monash University, Melbourne, VIC, Australia.

المصدر: Blood cancer journal [Blood Cancer J] 2024 May 02; Vol. 14 (1), pp. 77. Date of Electronic Publication: 2024 May 02.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't; Comparative Study

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE

مواضيع طبية MeSH: Adenine*/*analogs & derivatives, Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy , Leukemia, Lymphocytic, Chronic, B-Cell*/mortality , Adenine*/therapeutic use , Piperidines*/therapeutic use, Humans ; Male ; Pyrazoles/therapeutic use ; Female ; Pyrimidines/therapeutic use ; Aged ; Treatment Outcome ; Middle Aged

المؤلفون: Konttinen O; Biomolecular Science and Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA., Carmody J; Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, USA., Kurnik M; Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, USA., Johnson KA; Life Sciences Interdisciplinary Graduate Program, Department of Molecular Biosciences, University of Texas, Austin, TX, USA., Reich N; Biomolecular Science and Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA.; Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, USA.

المصدر: Nucleic acids research [Nucleic Acids Res] 2023 Jul 21; Vol. 51 (13), pp. 6883-6898.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Site-Specific DNA-Methyltransferase (Adenine-Specific)*/metabolism , DNA*/chemistry, Humans ; DNA Methylation ; DNA Modification Methylases/genetics ; DNA Modification Methylases/metabolism ; Methyltransferases/genetics ; Methyltransferases/metabolism ; Adenine/metabolism ; Kinetics ; Substrate Specificity

المؤلفون: Fujisawa K; Department of Environmental Oncology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 14; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Adenine Nucleotides*/metabolism , Adenylate Kinase*/metabolism, Animals ; Humans ; Nucleotides ; Adenine ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Adenosine Monophosphate ; Adenosine Triphosphate/metabolism

المؤلفون: Campbell L; King's College Hospital NHS Foundation Trust.; King's College London., Barbini B; King's College Hospital NHS Foundation Trust.; King's College London., Cromarty B; UK Community Advisory Board., Hamzah L; St George's Healthcare NHS Trust, London., Williams D; Brighton and Sussex University Hospitals, Brighton., Winston A; Imperial College Healthcare NHS Trust.; Imperial College, London, UK., Post FA; King's College Hospital NHS Foundation Trust.; King's College London.

مؤلفون مشاركون: FANTA trial team

المصدر: AIDS (London, England) [AIDS] 2024 Jul 15; Vol. 38 (9), pp. 1442-1445. Date of Electronic Publication: 2024 Jun 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8710219 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5571 (Electronic) Linking ISSN: 02699370 NLM ISO Abbreviation: AIDS Subsets: MEDLINE

مواضيع طبية MeSH: Tenofovir*/adverse effects , Tenofovir*/therapeutic use , Tenofovir*/analogs & derivatives , Alanine*/adverse effects , Alanine*/therapeutic use , Anti-HIV Agents*/adverse effects , Anti-HIV Agents*/therapeutic use , HIV Infections*/drug therapy , HIV Infections*/complications , Adenine*/analogs & derivatives , Adenine*/adverse effects , Adenine*/therapeutic use , Fanconi Syndrome*/chemically induced, Humans ; Male ; Female ; Adult ; Middle Aged

المؤلفون: Kim SM; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do, 17546, Republic of Korea., Han GU; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do, 17546, Republic of Korea., Kim SG; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do, 17546, Republic of Korea., Moon SH; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do, 17546, Republic of Korea., Shin SH; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do, 17546, Republic of Korea., Ryu BY; Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-Do, 17546, Republic of Korea. Electronic address: byryu@cau.ac.kr.

المصدر: Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Jul 15; Vol. 280, pp. 116544. Date of Electronic Publication: 2024 Jun 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7805381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2414 (Electronic) Linking ISSN: 01476513 NLM ISO Abbreviation: Ecotoxicol Environ Saf Subsets: MEDLINE

مواضيع طبية MeSH: Phthalic Acids*/toxicity , Autophagy*/drug effects , Apoptosis*/drug effects , Reactive Oxygen Species*/metabolism , Sesquiterpenes*/pharmacology , Acetylcysteine*/pharmacology , Adenine*/analogs & derivatives , Adenine*/pharmacology , Adenine*/toxicity , Cell Proliferation*/drug effects, Male ; Animals ; Mice ; Cell Line ; Plasticizers/toxicity ; Spermatogonia/drug effects

المؤلفون: Killock D; Nature Reviews Clinical Oncology, . nrclinonc@nature.com.

المصدر: Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2024 Jul; Vol. 21 (7), pp. 483.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500077 Publication Model: Print Cited Medium: Internet ISSN: 1759-4782 (Electronic) Linking ISSN: 17594774 NLM ISO Abbreviation: Nat Rev Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Piperidines*/therapeutic use , Adenine*/analogs & derivatives , Adenine*/therapeutic use , Pyrazoles*/therapeutic use , Pyrimidines*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Lymphoma, Mantle-Cell*/drug therapy, Humans ; Treatment Outcome ; Hematopoietic Stem Cell Transplantation

المؤلفون: Dong Q; Department I of Pharmacology, Center for Pharmacology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 24, Cologne, 50931, Germany. qdong2@smail.uni-koeln.de., Chen C; Department I of Pharmacology, Center for Pharmacology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 24, Cologne, 50931, Germany.; Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development, College of Veterinary Medicine, Northeast Agricultural University, 600 Changjiang Road, Xiangfang District, Harbin, 150030, People's Republic of China., Taubert M; Department I of Pharmacology, Center for Pharmacology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 24, Cologne, 50931, Germany., Bilal M; Department I of Pharmacology, Center for Pharmacology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 24, Cologne, 50931, Germany.; Department of Clinical Pharmacy, Institute of Pharmacy, University of Bonn, Bonn, Germany., Kinzig M; Institute for Biomedical and Pharmaceutical Research, Nürnberg-Heroldsberg, Germany., Sörgel F; Institute for Biomedical and Pharmaceutical Research, Nürnberg-Heroldsberg, Germany., Scherf-Clavel O; Department Pharmazie, Ludwig-Maximilians-Universität München, Butenandtstr. 5, 81377, München, Germany., Fuhr U; Department I of Pharmacology, Center for Pharmacology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 24, Cologne, 50931, Germany., Dokos C; Department I of Pharmacology, Center for Pharmacology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Gleueler Straße 24, Cologne, 50931, Germany.

المصدر: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2024 Jul; Vol. 80 (7), pp. 1069-1078. Date of Electronic Publication: 2024 Mar 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Organophosphonates*/pharmacokinetics , Organophosphonates*/blood , Organophosphonates*/administration & dosage , Adenine*/analogs & derivatives , Adenine*/pharmacokinetics , Adenine*/administration & dosage , Models, Biological*, Humans ; Male ; Adult ; Female ; Organic Anion Transport Protein 1/metabolism ; Organic Anion Transport Protein 1/genetics ; Drug Interactions ; Phenotype ; Middle Aged ; Young Adult ; Digoxin/pharmacokinetics ; Digoxin/blood ; Digoxin/administration & dosage ; Metformin/pharmacokinetics ; Metformin/administration & dosage ; Metformin/blood ; Sitagliptin Phosphate/pharmacokinetics ; Biological Availability

المؤلفون: Jyani G; Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India., Gupta N; Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, India. Electronic address: nidhiguptaonco@gmail.com.

المصدر: Value in health regional issues [Value Health Reg Issues] 2024 Jul; Vol. 42, pp. 100991. Date of Electronic Publication: 2024 May 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101592642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-1102 (Electronic) Linking ISSN: 22121099 NLM ISO Abbreviation: Value Health Reg Issues Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy , Leukemia, Lymphocytic, Chronic, B-Cell*/economics , Adenine*/analogs & derivatives , Adenine*/therapeutic use , Adenine*/economics , Cost-Benefit Analysis*/methods , Piperidines*/therapeutic use , Piperidines*/economics , Pyrimidines*/economics , Pyrimidines*/therapeutic use , Pyrazoles*/economics , Pyrazoles*/therapeutic use, Humans ; India/epidemiology ; Antineoplastic Agents/economics ; Antineoplastic Agents/therapeutic use