المؤلفون: Lars Harbaum, Christopher J. Rhodes, John Wharton, Allan Lawrie, Jason H. Karnes, Ankit A. Desai, William C. Nichols, Marc Humbert, David Montani, Barbara Girerd, Olivier Sitbon, Mario Boehm, Tatyana Novoyatleva, Ralph T. Schermuly, H. Ardeschir Ghofrani, Mark Toshner, David G. Kiely, Luke S. Howard, Emilia M. Swietlik, Stefan Gräf, Maik Pietzner, Nicholas W. Morrell, Martin R. Wilkins, L Southgate, RD Machado, J Martin, WH Ouwehand, MW Pauciulo, A Arora, K Lutz, F Ahmad, SL Archer, R Argula, ED Austin, D Badesch, S Bakshi, C Barnett, R Benza, N Bhatt, CD Burger, M Chakinala, J Elwing, T Fortin, RP Frantz, A Frost, JGN Garcia, J Harley, H He, NS Hill, R Hirsch, D Ivy, J Klinger, T Lahm, K Marsolo, LJ Martin, SD Nathan, RJ Oudiz, Z Rehman, I Robbins, DM Roden, EB Rosenzweig, G Saydain, R Schilz, RW Simms, M Simon, H Tang, AY Tchourbanov, T Thenappan, F Torres, AK Walsworth, RE Walter, RJ White, J Wilt, D Yung, R Kittles, J Aman, J Knight, KB Hanscombe, H Gall, A Ulrich, HJ Bogaard, C Church, JG Coghlan, R Condliffe, PA Corris, C Danesino, CG Elliott, A Franke, S Ghio, JSR Gibbs, AC Houweling, G Kovacs, M Laudes, RV MacKenzie Ross, S Moledina, M Newnham, A Olschewski, H Olschewski, AJ Peacock, J Pepke-Zaba, L Scelsi, W Seeger, CM Shaffer, O Sitbon, J Suntharalingam, C Treacy, A Vonk Noordegraaf, Q Waisfisz, SJ Wort, RC Trembath, M Germain, I Cebola, J Ferrer, P Amouyel, S Debette, M Eyries, F Soubrier, DA Trégouët

المساهمون: Harbaum, Lars [0000-0002-9422-6195], Lawrie, Allan [0000-0003-4192-9505], Montani, David [0000-0002-9358-6922], Sitbon, Olivier [0000-0002-1942-1951], Gräf, Stefan [0000-0002-1315-8873], Wilkins, Martin R [0000-0003-3926-1171], Apollo - University of Cambridge Repository, British Heart Foundation, The Academy of Medical Sciences

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Pulmonary Arterial Hypertension, Proteome, case-control studies, Hypertension, Pulmonary, Respiratory System, Blood Proteins, Critical Care and Intensive Care Medicine, Mendelian randomization, Humans, Familial Primary Pulmonary Hypertension, Netrins, Pathology, Molecular, Mendelian randomisation, protein quantitative trait loci, Thrombospondins, genome, 11 Medical and Health Sciences

وصف الملف: application/octet-stream

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f363dc083e705c01eb9c6d70a4b67afd
https://www.repository.cam.ac.uk/handle/1810/340465

المؤلفون: Marius M Hoeper, Hikmet Al-Hiti, Raymond L Benza, Sung-A Chang, Paul A Corris, J Simon R Gibbs, Ekkehard Grünig, Pavel Jansa, James R Klinger, David Langleben, Vallerie V McLaughlin, Gisela M B Meyer, Jaquelina Ota-Arakaki, Andrew J Peacock, Tomás Pulido, Stephan Rosenkranz, Carmine Dario Vizza, Anton Vonk-Noordegraaf, R James White, Mikyung Chang, Frank Kleinjung, Christian Meier, Karen Paraschin, Hossein Ardeschir Ghofrani, Gérald Simonneau, H Olschewski, M Delcroix, M Andrade-Lima, R de Amorim Corrêac, F Figueiredo Campos, J Ota Arakaki, G Meyer, R De Souza, D Langleben, H Al-Hiti, P Jansa, S Mellemkjær, F Bauer, D Montani, G Simonneau, D Drömann, H-A Ghofrani, E Grünig, M Halank, M Held, MM Hoeper, H Klose, N Kneidinger, H Leuchte, C Opitz, S Rosenkranz, H Wilkens, H Wirtz, H Karvounis, G Pitsiou, S Orfanos, M D'Alto, S Ghio, CD Vizza, P Vitulo, T Nakayama, H Maki, S Tatebe, M de los Rios Ibarra, T Pulido, A Van Dijk, A Vonk-Noordegraaf, T Roleder, G Castro, MJ Loureiro, S Robalo-Martins, JA Barberá, M Lázaro, GM Perez-Penate, A Román, C-C Cheng, C-H Hsu, H-H Hsu, E Atahan, N Mogulkoc Bishop, NG Okumus, Z Onen, H-J Chang, S-A Chang, J-S Lee, H-K Kim, JG Coghlan, PA Corris, AC Church, R Condliffe, JSR Gibbs, AJ Peacock, S Wort, R Allen, S Allen, R Awdish, RL Benza, S DeSouza, J Feldman, S Johri, JR Klinger, D Layish, J McConnell, VV McLaughlin, C Migliore, F Rahaghi, F Rischard, I Robbins, L Satterwhite, T Shah, R Sulica, RJ White

المساهمون: Pulmonary medicine, ACS - Pulmonary hypertension & thrombosis

المصدر: The Lancet Respiratory Medicine, 9(6), 573-584. Elsevier Limited
Hoeper, M M, Al-Hiti, H, Benza, R L, Chang, S-A, Corris, P A, Gibbs, J S R, Grünig, E, Jansa, P, Klinger, J R, Langleben, D, McLaughlin, V V, Meyer, G M B, Ota-Arakaki, J, Peacock, A J, Pulido, T, Rosenkranz, S, Vizza, C D, Vonk-Noordegraaf, A, White, R J, Chang, M, Kleinjung, F, Meier, C, Paraschin, K, Ghofrani, H A, Simonneau, G & The REPLACE investigators 2021, ' Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE) : a multicentre, open-label, randomised controlled trial ', The Lancet Respiratory Medicine, vol. 9, no. 6, pp. 573-584 . https://doi.org/10.1016/S2213-2600(20)30532-4
REPLACE investigators 2021, ' Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial ', The Lancet Respiratory Medicine, vol. 9, no. 6, pp. 573-584 . https://doi.org/10.1016/S2213-2600(20)30532-4

مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, multicentre, Sildenafil, phosphodiesterase-5 inhibitors, Riociguat, law.invention, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Maintenance therapy, Randomized controlled trial, law, Internal medicine, riociguat, pulmonary arterial hypertension, REPLACE, Clinical endpoint, Humans, Medicine, Prospective Studies, 030212 general & internal medicine, Adverse effect, Aged, Pulmonary Arterial Hypertension, business.industry, Middle Aged, Phosphodiesterase 5 Inhibitors, medicine.disease, Pulmonary hypertension, Tadalafil, Pyrimidines, 030228 respiratory system, chemistry, Pyrazoles, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56129be8d7d9bbfecf556d9b7ae7f504
https://research.vumc.nl/en/publications/422b5ce8-53f9-4f2f-8e03-8a80ae3dd2b8

المؤلفون: S. Stella, AD. Mateescu, A. Krivickiene, B. Fries, M. Drakopoulou, D. Lovric, M. Madeira, M. Cusma Piccione, D. Trifunovic, G. Pontone, N. Kouris, T. Caspar, M. Marketou, J. Almeida, TM. Crowe, R. Zayat, D. Erne, K. Hristova, P. Barbier, D. Djikic, L. Gabrielli, D. Szczesniak-Stanczyk, S. Ranjbar, B. De Chiara, F. Casadei, A. Peritore, F. Spano, G. Santambrogio, M. Vicario, I. Trolese, C. Gallina, C. Giannattasio, A. Moreo, M. Karvandi, LP. Badano, W. Brzozowski, R. Blaszczyk, M. Szyszko, R. Zarczuk, M. Janowski, A. Wysokinski, B. Stanczyk, M. Sitges, P. Castro, H. Verdejo, MP. Ocaranza, P. Sepulveda, S. Llevaneras, F. Baraona, M. Salinas, S. Lavanderos, N. Mujovic, B. Dejanovic, V. Peric, M. Marinkovic, N. Jankovic, B. Orbovic, D. Simic, M. Guglielmo, L. Salvini, G. Savioli, A. Dasheva, R. Marinov, S. Lasarov, I. Mitev, P. M, K. Rhodes, M. Bartlett, A. Chong, S. Wahi, M. Derwall, A. Ebeling, C. Nix, G. Marx, R. Autschbach, N. Hatam, P. Sonecki, MJ. Brewis, AC. Church, MK. Johnson, AJ. Peacock, R. Fontes-Carvalho, F. Sampaio, J. Ribeiro, P. Bettencourt, A. Leite-Moreira, A. Azevedo, J. Kontaraki, P. Parthenakis, S. Maragkoudakis, M. Touloupaki, A. Patrianakos, J. Konstantinou, M. Vernardos, J. Logakis, P. Vardas, S. El Ghannudi, P. Ohlmann, A. Lawson, O. Morel, M. Ohana, C. Roy, A. Gangi, P. Germain, P. Kostakou, A. Dagre, E. Trifou, I. Rodis, V. Kostopoulos, CD. Olympios, AI. Guaricci, M. Verdecchia, D. Andreini, A. Baggiano, V. Beltrama, G. Ferro, P. Carita', M. Pepi, G. Krljanac, L. Savic, M. Asanin, D. Matovic, J. Stepanovic, G. Stankovic, I. Mrdovic, A. Terrizzi, O. Trio, A. Oteri, G. D'amico, A. Ioppolo, G. Nucifora, M. Zucco, M. Sergi, A. Nicotera, I. Boretti, S. Carerj, C. Zito, R. Teixeira, L. Reis, P. Dinis, A. Fernandes, F. Caetano, I. Almeida, M. Costa, L. Goncalves, V. Reskovic Luksic, Z. Baricevic, D. Dosen, M. Pasalic, Z. Ostojic, M. Brestovac, J. Bulum, J. Separovic Hanzevacki, K. Toutouzas, K. Stathogiannis, A. Michelongona, G. Latsios, A. Synetos, G. Trantalis, O. Kaitozis, S. Brili, D. Tousoulis, D. Liu, K. Hu, W. Voelker, G. Ertl, F. Weidemann, S. Herrmann, B. Gumauskiene, E. Drebickaite, E. Ereminiene, JJ. Vaskelyte, A. Calin, M. Rosca, CC. Beladan, R. Enache, C. Calin, I. Cosei, S. Botezatu, M. Simion, C. Ginghina, BA. Popescu, I. Rosa, C. Marini, F. Ancona, A. Latib, M. Monitorano, A. Colombo, A. Margonato, E. Agricola

المصدر: European Heart Journal – Cardiovascular Imaging. 17:ii186.1-ii193

مصطلحات موضوعية: Radiology, Nuclear Medicine and imaging, General Medicine, Cardiology and Cardiovascular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::57483e64e8229985036bd1322a0953eb
https://doi.org/10.1093/ehjci/jew260

المؤلفون: MK Johnson, AJ Peacock, Wai-Ting Nicola Lee

المصدر: C27. RIGHT VENTRICULAR FUNCTION AND EXERCISE.

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, medicine, Cardiology, Stroke volume, medicine.disease, business, Pulmonary hypertension

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::45689c901f802f3015e0dcaeb7348839
https://doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4133

المؤلفون: K.E. Dawes, AJ Peacock, Geoffrey J. Laurent

المصدر: Clinical Science. 79:17P-17P

مصطلحات موضوعية: medicine.medical_specialty, education.field_of_study, Endocrinology, Chemistry, Internal medicine, Growth factor, medicine.medical_treatment, medicine, Chemotaxis, General Medicine, education, Endothelin 1, Endothelin 3

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fed8bfa2a785f1b7cb37d8b3e7e5e656
https://doi.org/10.1042/cs079017p

المؤلفون: Cj, Rhodes, Ghataorhe P, Wharton J, Kc, Rue-Albrecht, Hadinnapola C, Watson G, Bleda M, Haimel M, Coghlan G, Pa, Corris, Ls, Howard, Dg, Kiely, Aj, Peacock, Pepke-Zaba J, Toshner M, Sj, Wort, Js, Gibbs, Allan Lawrie, Gräf S, Nw, Morrell

المصدر: Europe PubMed Central

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::57048be21bb795dfc97b71fdbada793a
http://europepmc.org/abstract/med/27881557

المؤلفون: Rosenkranz S; Department of Cardiology, Heart Center at the University of Cologne, and Cologne Cardiovascular Research Center, University of Cologne, Germany. Electronic address: stephan.rosenkranz@uk-koeln.de., Feldman J; Arizona Pulmonary Specialists, Phoenix, AZ, USA., McLaughlin VV; Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, MI, USA., Rischard F; University of Arizona, Tucson, AZ, USA., Lange TJ; Dept of Internal Medicine II, Pulmonology, University Medical Center Regensburg, Germany., White RJ; University of Rochester Medical Center, Rochester, NY, USA., Peacock AJ; Scottish Pulmonary Vascular Unit, Regional Heart & Lung Centre, Glasgow, UK., Gerhardt F; Department of Cardiology, Heart Center at the University of Cologne, and Cologne Cardiovascular Research Center, University of Cologne, Germany., Ebrahimi R; Gilead Sciences, Foster City, CA, USA., Brooks G; Gilead Sciences, Foster City, CA, USA., Satler C; Gilead Sciences, Foster City, CA, USA., Frantz RP; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.

مؤلفون مشاركون: ARROW Study Group

المصدر: The Lancet. Respiratory medicine [Lancet Respir Med] 2022 Jan; Vol. 10 (1), pp. 35-46. Date of Electronic Publication: 2021 Aug 20.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: Pulmonary Arterial Hypertension*/drug therapy, Adolescent ; Adult ; Aged ; Benzamides ; Double-Blind Method ; Humans ; Imidazoles ; Middle Aged ; Pyridines ; Treatment Outcome ; Young Adult

المؤلفون: Grünig E; Centre for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, D-69126 Heidelberg, Germany., MacKenzie A; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK., Peacock AJ; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK., Eichstaedt CA; Centre for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, D-69126 Heidelberg, Germany.; Laboratory for Molecular Diagnostics, Institute of Human Genetics, Heidelberg University, Heidelberg, Germany., Benjamin N; Centre for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, D-69126 Heidelberg, Germany., Nechwatal R; Rehabilitation Center Koenigstuhl, Heidelberg, Germany., Ulrich S; Clinic of Pulmonology, University Hospital and University of Zurich, Zurich, Switzerland., Saxer S; Clinic of Pulmonology, University Hospital and University of Zurich, Zurich, Switzerland., Bussotti M; Cardiac Rehabilitation Department, IRCCS Maugeri Clinical Scientific Institutes, Milan, Italy., Sommaruga M; Cardiac Rehabilitation Department, IRCCS Maugeri Clinical Scientific Institutes, Milan, Italy., Ghio S; Divisione di Cardiologia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy., Gumbiene L; Competence Centre of Pulmonary Hypertension, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.; Faculty of Medicine, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania., Palevičiūtė E; Competence Centre of Pulmonary Hypertension, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.; Faculty of Medicine, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania., Jurevičienė E; Competence Centre of Pulmonary Hypertension, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.; Faculty of Medicine, Institute of Clinical Medicine, Vilnius University, Vilnius, Lithuania., Cittadini A; Department of Translational Medical Sciences, 'Federico II' University, Naples, Italy., Stanziola AA; Department of Clinical Medicine and Surgery, 'Federico II' University, Naples, Italy., Marra AM; Centre for Pulmonary Hypertension, Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Röntgenstraße 1, D-69126 Heidelberg, Germany.; Department of Cardiovascular Imaging, IRCCS S.D.N., Naples, Italy., Kovacs G; Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria., Olschewski H; Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria., Barberà JA; Department of Pulmonary Medicine, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona and Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Spain., Blanco I; Department of Pulmonary Medicine, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona and Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Spain., Spruit MA; Research and Development, Ciro, Horn, Netherlands.; Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.; NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, The Netherlands.; REVAL-Rehabilitation Research Center, BIOMED-Biomedical Research Institute, Faculty of Rehabilitation Sciences, Hasselt University, Diepenbeek, Belgium., Franssen FME; Department of Research and Education, CIRO, Horn, The Netherlands., Vonk Noordegraaf A; Department of Pulmonology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, VU University Medical Center, Amsterdam, The Netherlands., Reis A; Department of Internal Medicine, Hospital Geral de Santo António, Porto, Portugal., Santos M; Department of Internal Medicine, Hospital Geral de Santo António, Porto, Portugal., Viamonte SG; Centro de Rehabilitação do Norte/Centro Hospitalar Vila Nova de Gaia Espinho, Porto, Portugal., Demeyer H; Department of Pneumology, University Hospital Leuven, Leuven, Belgium.; Department of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.; Department of Rehabilitation Sciences, Ghent University, Ghent, Belgium., Delcroix M; Department of Pneumology, University Hospital Leuven, Leuven, Belgium., Bossone E; Department of Cardiology, Antonio Carderelli Hospital, Naples, Italy., Johnson M; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.

المصدر: European heart journal [Eur Heart J] 2021 Jun 14; Vol. 42 (23), pp. 2284-2295.

نوع المنشور: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE

مواضيع طبية MeSH: Hypertension, Pulmonary*/therapy, Adult ; Aged ; Chronic Disease ; Europe ; Exercise ; Exercise Tolerance ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Quality of Life

المؤلفون: Hoeper MM; Clinic for Respiratory Medicine, Hannover Medical School, member of the German Center for Lung Research (DZL), Hannover, Germany. Electronic address: Hoeper.Marius@mh-hannover.de., Al-Hiti H; Department of Cardiology, Institute of Clinical and Experimental Medicine-IKEM, Prague, Czech Republic., Benza RL; Division of Cardiovascular Diseases, Ohio State University, Columbus, OH, USA., Chang SA; Division of Cardiology, Department of Medicine, Heart Vascular and Stroke Institute Imaging Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam-gu, Seoul, South Korea., Corris PA; Institute of Cellular Medicine, Newcastle University, Newcastle, UK., Gibbs JSR; National Heart and Lung Institute, Imperial College London, and Department of Cardiology, National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., Grünig E; Centre for Pulmonary Hypertension, Thoraxklinik at Heidelberg University Hospital, Translational Lung Research Center (TLRC), member of DZL, Heidelberg, Germany., Jansa P; 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University, and General University Hospital, Prague, Czech Republic., Klinger JR; Division of Pulmonary, Sleep, and Critical Care Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, RI, USA., Langleben D; Center for Pulmonary Vascular Disease and Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, QC, Canada., McLaughlin VV; Division of Cardiovascular Medicine, University of Michigan, Michigan Medicine, Ann Arbor, MI, USA., Meyer GMB; Centro de Hipertensão Pulmonar, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, Brazil., Ota-Arakaki J; Pulmonary Circulation Group, Department of Medicine, Universidade Federal de São Paulo-Hospital São Paulo, São Paulo, Brazil., Peacock AJ; Scottish Pulmonary Vascular Unit, Regional Lung and Heart Centre, Glasgow, UK., Pulido T; Cardiopulmonary Department, National Heart Institute, Mexico City, Mexico., Rosenkranz S; Clinic III for Internal Medicine (Cardiology), Cologne Cardiovascular Research Center (CCRC), and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Vizza CD; Pulmonary Hypertension Unit, Department of Cardiovascular and Respiratory Disease, La Sapienza University of Rome, Rome, Italy., Vonk-Noordegraaf A; Department of Pneumology, VU University Medical Center, Amsterdam, Netherlands., White RJ; University of Rochester Medical Center, Rochester, NY, USA., Chang M; Global Medical Affairs, Bayer AG, Berlin, Germany., Kleinjung F; Global Medical Affairs, Bayer AG, Berlin, Germany., Meier C; Global Medical Affairs, Bayer AG, Berlin, Germany., Paraschin K; Bayer AG, São Paulo, Brazil., Ghofrani HA; University of Giessen and Marburg Lung Center, member of DZL, Giessen, Germany; Department of Pneumology, Kerchoff Clinic, Bad Nauheim, Germany; Department of Medicine, Imperial College London, London, UK., Simonneau G; Assistance Publique-Hôpitaux de Paris, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Saclay, Laboratoire d'Excellence en Recherche sur le Médicament et Innovation Thérapeutique, and Inserm U999, Le Kremlin-Bicêtre, France.

مؤلفون مشاركون: REPLACE investigators

المصدر: The Lancet. Respiratory medicine [Lancet Respir Med] 2021 Jun; Vol. 9 (6), pp. 573-584. Date of Electronic Publication: 2021 Mar 24.

نوع المنشور: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors/*therapeutic use , Pulmonary Arterial Hypertension/*drug therapy , Pyrazoles/*therapeutic use , Pyrimidines/*therapeutic use, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Young Adult

المؤلفون: Lewis RA; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.; Dept of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Armstrong I; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK., Bergbaum C; National Pulmonary Hypertension Service, Royal Brompton Hospital and Imperial College, London, UK., Brewis MJ; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK., Cannon J; Pulmonary Vascular Disease Unit, Royal Papworth Hospital, Cambridge, UK., Charalampopoulos A; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK., Church AC; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK., Coghlan JG; Pulmonary Hypertension Unit, Royal Free Hospital, London, UK., Davies RJ; National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., Dimopoulos K; National Pulmonary Hypertension Service, Royal Brompton Hospital and Imperial College, London, UK., Elliot C; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK., Gibbs JSR; National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., Gin-Sing W; National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., Haji G; National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., Hameed AG; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.; Dept of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Howard LS; National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., Johnson MK; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK., Kempny A; National Pulmonary Hypertension Service, Royal Brompton Hospital and Imperial College, London, UK., Kiely DG; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.; Dept of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Lo Giudice F; National Pulmonary Hypertension Service, Hammersmith Hospital, London, UK., McCabe C; National Pulmonary Hypertension Service, Royal Brompton Hospital and Imperial College, London, UK., Peacock AJ; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK., Peleyeju O; Pulmonary Hypertension Unit, Royal Free Hospital, London, UK., Pepke-Zaba J; Pulmonary Vascular Disease Unit, Royal Papworth Hospital, Cambridge, UK., Polwarth G; Pulmonary Vascular Disease Unit, Royal Papworth Hospital, Cambridge, UK., Price L; National Pulmonary Hypertension Service, Royal Brompton Hospital and Imperial College, London, UK., Sabroe I; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.; Dept of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Schreiber BE; Pulmonary Hypertension Unit, Royal Free Hospital, London, UK., Sheares K; Pulmonary Vascular Disease Unit, Royal Papworth Hospital, Cambridge, UK., Taboada D; Pulmonary Vascular Disease Unit, Royal Papworth Hospital, Cambridge, UK., Thompson AAR; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.; Dept of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Toshner MR; Pulmonary Vascular Disease Unit, Royal Papworth Hospital, Cambridge, UK., Wanjiku I; Pulmonary Hypertension Unit, Royal Free Hospital, London, UK., Wort SJ; National Pulmonary Hypertension Service, Royal Brompton Hospital and Imperial College, London, UK., Yorke J; School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK., Condliffe R; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK robin.condliffe@nhs.net.

المصدر: The European respiratory journal [Eur Respir J] 2021 Feb 25; Vol. 57 (2). Date of Electronic Publication: 2021 Feb 25 (Print Publication: 2021).

نوع المنشور: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 8803460 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1399-3003 (Electronic) Linking ISSN: 09031936 NLM ISO Abbreviation: Eur Respir J Subsets: MEDLINE

مواضيع طبية MeSH: Connective Tissue Diseases*/complications , Hypertension, Pulmonary* , Pulmonary Arterial Hypertension*, Humans ; Quality of Life ; United Kingdom