المؤلفون: G Guanechea, C Damián, AJ Thrasher, G Santilli, M Aldea, B Campo, C Mesa Núñez, E Almarza, D León Rico, Uam . Madrid, Spain., M.L. Lozano, JA Bueren, D B Kohn, C. Carrascoso Rubio

المصدر: IBJ Plus.

مصطلحات موضوعية: Haematopoiesis, business.industry, Cancer research, medicine, Stem cell, medicine.disease, business, Leukocyte adhesion deficiency

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f92a1452e25f75015e222ba4fb1f06f
https://doi.org/10.24217/2531-0151.18v1s2.00024

المؤلفون: P. Vassallo Agius, Nigel Klein, Melanie J. Newport, S. D’Souza, Michael Levin, AJ Thrasher, Herbert Manfred Lenicker, Jenefer M. Blackwell, I. N. Brown, Panos Kalabalikis, E. G. Davies

المصدر: The Lancet. 345:79-83

مصطلحات موضوعية: Adult, Male, medicine.drug_class, Antibiotics, Hepatosplenomegaly, Mycobacterium Infections, Nontuberculous, Disease, Lymphocyte Activation, Interferon-gamma, Immune system, Antigen, medicine, Humans, Genetic Predisposition to Disease, Interferon gamma, Child, Antigens, Bacterial, biology, Tumor Necrosis Factor-alpha, Infant, Nontuberculous Mycobacteria, General Medicine, biology.organism_classification, Pedigree, Endotoxins, Chronic infection, Child, Preschool, Chronic Disease, Immunology, Female, Mycobacterium fortuitum, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c2de40f3364e5ba7f05257277fb347
https://doi.org/10.1016/s0140-6736(95)90059-4

المؤلفون: G Bouma, AJ Thrasher

المصدر: Blood and Bone Marrow Pathology (Second Edition)

مصطلحات موضوعية: medicine.anatomical_structure, Phagocyte, business.industry, Medicine, business, Neuroscience, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4a2786e95f3a8c47f45e8f0381363f01
https://doi.org/10.1016/b978-0-7020-3147-2.00017-1

المؤلفون: Aj, Schilz, Brouns G, Knöss H, Oliver Ottmann, Hoelzer D, Aa, Fauser, Aj, Thrasher, Grez M

المصدر: Europe PubMed Central

مصطلحات موضوعية: Recombinant Fusion Proteins, Genetic Vectors, Hematopoietic Stem Cell Transplantation, Mice, SCID, Receptors, Nerve Growth Factor, Fetal Blood, Hematopoietic Stem Cells, Transfection, Receptor, Nerve Growth Factor, Culture Media, Serum-Free, Colony-Forming Units Assay, Mice, Retroviridae, Genes, Reporter, Mice, Inbred NOD, Animals, Humans, Cells, Cultured, Bone Marrow Transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fc22e71cd38a3b71ee6510ad053f08cc
https://pubmed.ncbi.nlm.nih.gov/9787152

المؤلفون: Malinova D, Fritzsche M, Cr, Nowosad, Armer H, Pm, Munro, Mp, Blundell, Charras G, Pavel Tolar, Bouma G, Aj, Thrasher

المصدر: Europe PubMed Central
Journal of Leukocyte Biology
Malinova, D, Fritzsche, M, Nowosad, C R, Armer, H, Munro, P M G, Blundell, M P, Charras, G, Tolar, P, Bouma, G & Thrasher, A J 2016, ' WASp-Dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts ', Journal of Leukocyte Biology, vol. 99, no. 5, pp. 699-710 . https://doi.org/10.1189/jlb.2A0215-050RR

مصطلحات موضوعية: Immunological Synapses, ICAM-1, T-Lymphocytes, Immunology, Lipid Bilayers, chemical and pharmacologic phenomena, macromolecular substances, Cell Communication, Lymphocyte Activation, DC, Immunology and Allergy, Animals, podosomes, Cell Biology, Dendritic Cells, respiratory system, Intercellular Adhesion Molecule-1, Receptors, Signal Transduction, & Genes, Mice, Inbred C57BL, Actin Cytoskeleton, Podosomes, FRAP, Arp2/3, human activities, Wiskott-Aldrich Syndrome Protein, Fluorescence Recovery After Photobleaching

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::051ffbd5562b7fc368dd4b2353481353
http://europepmc.org/abstract/med/26590149

المؤلفون: Yeung J; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK; UCL Cancer Institute, 72 Huntley Street, London, UK., Liao A; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Shaw M; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Silva S; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Vetharoy W; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Rico DL; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Kirby I; ADC Therapeutics UK (Ltd), Imperial College White City Campus, 84 Wood Lane, London W12 0BZ, UK., Zammarchi F; ADC Therapeutics UK (Ltd), Imperial College White City Campus, 84 Wood Lane, London W12 0BZ, UK., Havenith K; ADC Therapeutics UK (Ltd), Imperial College White City Campus, 84 Wood Lane, London W12 0BZ, UK., de Haan L; ADC Therapeutics UK (Ltd), Imperial College White City Campus, 84 Wood Lane, London W12 0BZ, UK., van Berkel PH; ADC Therapeutics UK (Ltd), Imperial College White City Campus, 84 Wood Lane, London W12 0BZ, UK., Sebire N; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 1JH, UK., Ogunbiyi OK; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 1JH, UK., Booth C; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 1JH, UK., Gaspar HB; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Thrasher AJ; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK., Chester KA; UCL Cancer Institute, 72 Huntley Street, London, UK., Amrolia PJ; UCL Great Ormond Street Institute of Child Health, Zayed Centre of Research, 20 Guilford Street, London WC1N 1DZ, UK; Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London WC1N 1JH, UK. Electronic address: persis.amrolia@gosh.nhs.uk.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Jun 05; Vol. 32 (6), pp. 1672-1686. Date of Electronic Publication: 2024 Mar 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Immunoconjugates*/pharmacology , Leukocyte Common Antigens*/metabolism , Genetic Therapy*/methods , Hematopoietic Stem Cell Transplantation*/methods , Benzodiazepines*/pharmacology , Benzodiazepines*/chemistry, Animals ; Humans ; Mice ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/drug effects ; Rats ; Transplantation Conditioning/methods ; Disease Models, Animal ; Antibodies, Monoclonal/pharmacology ; Pyrroles

المؤلفون: Whittaker TE; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Moula SE; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Bahal S; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Bakri FG; Division of Infectious Diseases, Department of Medicine, Jordan University Hospital, Amman, Jordan.; Infectious Diseases and Vaccine Center, University of Jordan, Amman, Jordan., Hayajneh WA; Division of Infectious Diseases, Department of Pediatrics, Jordan University of Science & Technology, Irbid, Jordan., Daoud AK; Division of Immunology, Department of Internal Medicine, Jordan University of Science & Technology, Irbid, Jordan., Naseem A; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Cavazza A; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Thrasher AJ; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; NIHR Great Ormond Street Hospital Biomedical Research Center, London, United Kingdom., Santilli G; Infection, Immunity, and Inflammation Research and Teaching Department, UCL, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.

المصدر: Human gene therapy [Hum Gene Ther] 2024 Apr; Vol. 35 (7-8), pp. 298-312. Date of Electronic Publication: 2024 Jan 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

مواضيع طبية MeSH: Granulomatous Disease, Chronic*/genetics , Granulomatous Disease, Chronic*/therapy, Humans ; Gene Editing ; Genetic Therapy/methods ; Antigens, CD34/genetics ; Hematopoietic Stem Cells/metabolism ; CRISPR-Cas Systems

المؤلفون: Rai R; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Steinberg Z; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Romito M; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Zinghirino F; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Hu YT; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., White N; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Naseem A; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Thrasher AJ; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; NIHR Great Ormond Street Hospital Biomedical Research Center, London, United Kingdom., Turchiano G; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom., Cavazza A; Infection, Immunity, and Inflammation Teaching and Research Department, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.; NIHR Great Ormond Street Hospital Biomedical Research Center, London, United Kingdom.; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Modena, Italy.

المصدر: Human gene therapy [Hum Gene Ther] 2024 Apr; Vol. 35 (7-8), pp. 269-283. Date of Electronic Publication: 2024 Feb 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: M.A. Liebert Country of Publication: United States NLM ID: 9008950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7422 (Electronic) Linking ISSN: 10430342 NLM ISO Abbreviation: Hum Gene Ther Subsets: MEDLINE

مواضيع طبية MeSH: Severe Combined Immunodeficiency*/genetics , Severe Combined Immunodeficiency*/therapy, Infant, Newborn ; Humans ; T-Lymphocytes/metabolism ; CRISPR-Cas Systems ; Hematopoietic Stem Cells/metabolism ; Gene Editing/methods ; Receptors, Interleukin-7/genetics ; Receptors, Interleukin-7/metabolism

المؤلفون: Bahal S; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Zinicola M; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Moula SE; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Whittaker TE; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Schejtman A; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Naseem A; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Blanco E; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Vetharoy W; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Hu YT; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Rai R; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Gomez-Castaneda E; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Cunha-Santos C; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Burns SO; University College London Institute of Immunity and Transplantation, London, United Kingdom; Department of Immunology, Royal Free London National Health Service Foundation Trust, London, United Kingdom., Morris EC; University College London Institute of Immunity and Transplantation, London, United Kingdom; Department of Immunology, Royal Free London National Health Service Foundation Trust, London, United Kingdom., Booth C; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital, National Health Service Foundation Trust, London, United Kingdom., Turchiano G; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Cavazza A; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom., Thrasher AJ; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital, National Health Service Foundation Trust, London, United Kingdom., Santilli G; Infection, Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, United Kingdom. Electronic address: g.santilli@ucl.ac.uk.

المصدر: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 Mar 11. Date of Electronic Publication: 2024 Mar 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE

المؤلفون: Vaidyanathan S; Center for Gene Therapy, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.; Department of Pediatrics, The Ohio State University, Columbus, OH 43210, USA., Kerschner JL; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH 44106, USA., Paranjapye A; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH 44106, USA., Sinha V; Department of Pediatrics, Stanford University, Palo Alto, CA 94305, USA., Lin B; Department of Developmental, Molecular, and Chemical Biology, Tufts University, Boston, MA 02111, USA., Bedrosian TA; Department of Pediatrics, The Ohio State University, Columbus, OH 43210, USA.; Steve and Cindy Rasmussen Institute for Genomic Medicine, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA., Thrasher AJ; Infection, Immunity, and Inflammation Research and Teaching Department, Zayed Centre for Research Into Rare Disease in Children, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK., Turchiano G; Infection, Immunity, and Inflammation Research and Teaching Department, Zayed Centre for Research Into Rare Disease in Children, Great Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK., Harris A; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH 44106, USA., Porteus MH; Department of Pediatrics, Stanford University, Palo Alto, CA 94305, USA.

المصدر: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2024 Feb 02; Vol. 35 (1), pp. 102134. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE