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المؤلفون: Maria C. Costanzo, Marcin von Grotthuss, Jeffrey Massung, Dongkeun Jang, Lizz Caulkins, Ryan Koesterer, Clint Gilbert, Ryan P. Welch, Parul Kudtarkar, Quy Hoang, Andrew P. Boughton, Preeti Singh, Ying Sun, Marc Duby, Annie Moriondo, Trang Nguyen, Patrick Smadbeck, Benjamin R. Alexander, MacKenzie Brandes, Mary Carmichael, Peter Dornbos, Todd Green, Kenneth C. Huellas-Bruskiewicz, Yue Ji, Alexandria Kluge, Aoife C. McMahon, Josep M. Mercader, Oliver Ruebenacker, Sebanti Sengupta, Dylan Spalding, Daniel Taliun, Philip Smith, Melissa K. Thomas, Beena Akolkar, M. Julia Brosnan, Andriy Cherkas, Audrey Y. Chu, Eric B. Fauman, Caroline S. Fox, Tania Nayak Kamphaus, Melissa R. Miller, Lynette Nguyen, Afshin Parsa, Dermot F. Reilly, Hartmut Ruetten, David Wholley, Norann A. Zaghloul, Gonçalo R. Abecasis, David Altshuler, Thomas M. Keane, Mark I. McCarthy, Kyle J. Gaulton, Jose C. Florez, Michael Boehnke, Noël P. Burtt, Jason Flannick, Gonçalo Abecasis, Nicholette D. Allred, Jennifer E. Below, Richard Bergman, Joline W.J. Beulens, John Blangero, Krister Bokvist, Erwin Bottinger, Donald Bowden, Christopher Brown, Kenneth Bruskiewicz, Inês Cebola, John Chambers, Yii-Der Ida Chen, Christopher Clark, Melina Claussnitzer, Nancy J. Cox, Marcel den Hoed, Duc Dong, Ravindranath Duggirala, Josée Dupuis, Petra J.M. Elders, Jesse M. Engreitz, Eric Fauman, Jorge Ferrer, Paul Flicek, Matthew Flickinger, Timothy M. Frayling, Kelly A. Frazer, Anna L. Gloyn, Craig L. Hanis, Robert Hanson, Andrew T. Hattersley, Hae Kyung Im, Sidra Iqbal, Suzanne B.R. Jacobs, Dong-Keun Jang, Tad Jordan, Tania Kamphaus, Fredrik Karpe, Seung K. Kim, Kasper Lage, Leslie A. Lange, Mitchell Lazar, Donna Lehman, Ching-Ti Liu, Ruth J.F. Loos, Ronald Ching-wan Ma, Patrick MacDonald, Matthew T. Maurano, Gil McVean, James B. Meigs, Braxton Mitchell, Karen L. Mohlke, Samuel Morabito, Claire Morgan, Shannon Mullican, Sharvari Narendra, Maggie C.Y. Ng, Colin N.A. Palmer, Stephen C.J. Parker, Antonio Parrado, Aaron C. Pawlyk, Ewan R. Pearson, Andrew Plump, Michael Province, Thomas Quertermous, Susan Redline, Bing Ren, Stephen S. Rich, J. Brent Richards, Jerome I. Rotter, Rany M. Salem, Maike Sander, Michael Sanders, Dharambir Sanghera, Laura J. Scott, David Siedzik, Xueling Sim, Robert Sladek, Kerrin Small, Peter Stein, Heather M. Stringham, Katalin Susztak, Leen M. ’t Hart, Kent Taylor, Jennifer A. Todd, Miriam S. Udler, Benjamin Voight, Andre Wan, Kaan Yuksel
المساهمون: Epidemiology and Data Science, ACS - Diabetes & metabolism, ACS - Heart failure & arrhythmias, APH - Health Behaviors & Chronic Diseases, General practice
المصدر: 710.e6
AMP-T2D Consortium 2023, ' The Type 2 Diabetes Knowledge Portal : An open access genetic resource dedicated to type 2 diabetes and related traits ', Cell Metabolism, vol. 35, no. 4, pp. 695-710.e6 . https://doi.org/10.1016/j.cmet.2023.03.001
Cell Metab
Cell metabolism, vol 35, iss 4
Cell Metabolism, 35(4), 695-710.e6. Cell Pressمصطلحات موضوعية: Physiology, data sharing, T2DKP, effector genes, Medical Biochemistry and Metabolomics, Article, Access to Information, Endocrinology & Metabolism, CMDKP, Diabetes Mellitus, genomics, Genetics, Humans, GWAS, Prospective Studies, Molecular Biology, Metabolic and endocrine, diabetes, Human Genome, Cell Biology, AMP-T2D Consortium, Phenotype, portal, Good Health and Well Being, genetic support, genetic associations, Biochemistry and Cell Biology, Type 2
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04094df70ceb068c99b961c7447fbab0
http://hdl.handle.net/10044/1/104941 -
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المؤلفون: Aaron C. Pawlyk, Zhaoxia Ren, Andrew A. Bremer
المصدر: American Journal of Obstetrics and Gynecology. 225:33-42
مصطلحات موضوعية: Research design, education.field_of_study, medicine.medical_specialty, Pregnancy, 030219 obstetrics & reproductive medicine, business.industry, Population, Obstetrics and Gynecology, medicine.disease, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Clinical research, Drug development, Family medicine, Common Rule, Medicine, 030212 general & internal medicine, Adverse effect, education, business
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المصدر: Journal of clinical pharmacologyReferences. 62
مصطلحات موضوعية: Pharmacology, Humans, National Institute of Child Health and Human Development (U.S.), Pharmacology (medical), Child, United States
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المؤلفون: George P. Giacoia, Aaron C. Pawlyk, Perdita Taylor-Zapata, Zhaoxia Ren, Margaret C. Grabb, Lesly Samedy-Bates
المصدر: The Journal of Clinical Pharmacology. 61
مصطلحات موضوعية: medicine.medical_specialty, Physiologically based pharmacokinetic modelling, Prescription Drugs, Drug Industry, Models, Biological, Pediatrics, Drug Development, medicine, Humans, Computer Simulation, Drug Dosage Calculations, Pharmacology (medical), Medical physics, National Institute of Mental Health (U.S.), Pharmacology, Clinical Trials as Topic, Dose-Response Relationship, Drug, United States Food and Drug Administration, business.industry, Perspective (graphical), National Institute of Child Health and Human Development (U.S.), United States, Pharmacometrics, Clinical trial, business, Dose selection
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5
المؤلفون: Yaning Wang, Lynne Yao, Issam Zineh, Aaron C. Pawlyk, Susan McCune, Gilbert J. Burckart, Shirley Seo, George P. Giacoia
المصدر: Clin Pharmacol Ther
مصطلحات موضوعية: Knowledge Bases, Ontogeny, MEDLINE, 030226 pharmacology & pharmacy, Article, law.invention, 03 medical and health sciences, Child Development, 0302 clinical medicine, Drug Development, law, Humans, Pharmacology (medical), Child, Pharmacology, Medical education, Clinical pharmacology, business.industry, Child development, Clinical method, Pediatric drug, Holy Grail, Knowledge base, 030220 oncology & carcinogenesis, Pharmacology, Clinical, Psychology, business
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6
المؤلفون: Christine M. Colvis, Christopher M. Austin, Jenna Baker, Aaron C. Pawlyk, Ronald N. Margolis, Griffin P. Rodgers, James M. Anderson
المصدر: Nature reviews. Drug discovery. 17(5)
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Focus (computing), Biomedical Research, Genome, Human, Druggability, MEDLINE, Proteins, Pilot Projects, General Medicine, Computational biology, Genome, Human genetics, United States, Article, 03 medical and health sciences, 030104 developmental biology, National Institutes of Health (U.S.), Political science, Drug Discovery, Common fund, Humans, Human genome, Relevance (information retrieval)
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المؤلفون: Alan R. Shuldiner, Jose C. Florez, Catherine McKeon, Aaron C. Pawlyk, Kathleen M. Giacomini
المصدر: Diabetes
مصطلحات موضوعية: medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, Pharmacology, Pharmacotherapy, Health care, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Adverse effect, Intensive care medicine, business.industry, Precision medicine, medicine.disease, Metformin, 3. Good health, Diabetes Mellitus, Type 2, Pharmacogenetics, Pharmacogenomics, Perspectives in Diabetes, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1108d96ed180ec70e11898170c791b33
http://europepmc.org/articles/PMC4113063 -
8
المؤلفون: George Niederehe, Ron Johnson, Grace L. Shen, Aaron C. Pawlyk, Alison Deckhut Augustine, Ronald A. Kohanski, Leslie A. Frieden, Felipe Sierra, Francesca Macchiarini, Evan C. Hadley, Bradley C. Wise, Young S. Oh, Henry Rodriguez, Julia H. Rowland, Partap S. Khalsa, John B. Burch, Xiao Ling Li, T. Kevin Howcroft
المصدر: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 69:S1-S3
مصطلحات موضوعية: Gerontology, Aging, medicine.medical_specialty, Population ageing, Modern medicine, Biomedical Research, Supplement Issue: Frontiers in Geroscience, Alternative medicine, Global Health, Life Expectancy, Humans, Medicine, Disease burden, geography, Summit, geography.geographical_feature_category, Geroscience, business.industry, Public health, Congresses as Topic, Chronic disease, Geriatrics, Chronic Disease, Morbidity, Geriatrics and Gerontology, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a795e3b9d67ffb023ee82dbf08762c82
https://doi.org/10.1093/gerona/glu041 -
9
المؤلفون: Joel A. Cassel, Aaron C. Pawlyk, Benjamin E. Blass, Allen B. Reitz
المصدر: SLAS Discovery. 15:1099-1106
مصطلحات موضوعية: High-throughput screening, TAR DNA-Binding Protein 43, Plasma protein binding, Biology, Biochemistry, Article, Analytical Chemistry, Small Molecule Libraries, chemistry.chemical_compound, mental disorders, Humans, Biotinylation, Radiometry, HIV Long Terminal Repeat, Repetitive Sequences, Nucleic Acid, Oligonucleotide, Temperature, RNA, DNA, Molecular biology, High-Throughput Screening Assays, DNA-Binding Proteins, Kinetics, chemistry, Nucleic acid, Molecular Medicine, Protein Binding, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c379b230e2542be88f46f9a69ef80a80
https://doi.org/10.1177/1087057110382778 -
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المؤلفون: Allen B. Reitz, Joel A. Cassel, Aaron C. Pawlyk
المصدر: Current Pharmaceutical Design. 16:2053-2073
مصطلحات موضوعية: Adult, Pathology, medicine.medical_specialty, SOD1, Population, Disease, Bioinformatics, Central nervous system disease, Drug Delivery Systems, Superoxide Dismutase-1, Degenerative disease, Drug Discovery, Animals, Humans, Medicine, Amyotrophic lateral sclerosis, education, Pharmacology, education.field_of_study, Superoxide Dismutase, business.industry, Drug discovery, Amyotrophic Lateral Sclerosis, Neurodegeneration, medicine.disease, DNA-Binding Proteins, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3c561e067ae8ccd41884dee66e2b06
https://doi.org/10.2174/138161210791293024