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المؤلفون: Aaron G. Dale, Alessandra Porcu, John Mann, Stephen Neidle
المصدر: Dale, A G, Porcu, A, Mann, J & Neidle, S 2022, ' The mechanism of resistance in Escherichia coli to ridinilazole and other antibacterial head-to-head bis-benzimidazole compounds ', Medicinal Chemistry Research, vol. 31, pp. 1176-1191 . https://doi.org/10.1007/s00044-022-02918-7
مصطلحات موضوعية: resistance, Organic Chemistry, E coli, Appy gene, General Pharmacology, Toxicology and Pharmaceutics, ridinilazole, bis-benzimidazoles, Original Research
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd0e70d630d806e5367a654aae96d16
https://pure.qub.ac.uk/en/publications/a98611e0-51dd-4569-b243-0cba0d6a4ecf -
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المؤلفون: Stephan A. Ohnmacht, Marialuisa Micco, Aaron G. Dale, Ingrida Pazitna, Mekala Gunaratnam, Anthony P. Reszka, Gavin W. Collie, Stephen Neidle
المصدر: Journal of Medicinal Chemistry. 56:2959-2974
مصطلحات موضوعية: Models, Molecular, Telomerase, Drug Evaluation, Preclinical, Antineoplastic Agents, Naphthalenes, Imides, Ligands, G-quadruplex, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Humans, heterocyclic compounds, Promoter, Telomere, Small molecule, In vitro, G-Quadruplexes, Pancreatic Neoplasms, Biochemistry, chemistry, Cell culture, Drug Design, Molecular Medicine, Drug Screening Assays, Antitumor, DNA
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المؤلفون: Rupesh Nanjunda, Caterina Lombardo, Sandra J. Strauss, Aaron G. Dale, W. David Wilson, Alan K. Todd, Stephen Neidle, Sarah J. Welsh
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:5984-5988
مصطلحات موضوعية: Hypoxia-Inducible Factor 1, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Ligands, G-quadruplex, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Transcription (biology), Cell Line, Tumor, Drug Discovery, Basic Helix-Loop-Helix Transcription Factors, medicine, Humans, heterocyclic compounds, RNA, Messenger, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Cell Proliferation, Osteosarcoma, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Fibroblasts, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, Kidney Neoplasms, G-Quadruplexes, Mechanism of action, Hypoxia-inducible factors, Click chemistry, Molecular Medicine, Drug Screening Assays, Antitumor, medicine.symptom, DNA
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المؤلفون: John Mann, Jason Hinds, Aaron G. Dale, Peter W. Taylor, Stephen Neidle
المصدر: Biochemistry. 51:5860-5871
مصطلحات موضوعية: DNA Topoisomerase IV, DNA, Bacterial, Staphylococcus aureus, DNA damage, Stereochemistry, Microbial Sensitivity Tests, Biochemistry, DNA gyrase, chemistry.chemical_compound, medicine, Humans, Topoisomerase II Inhibitors, DNA Breaks, Single-Stranded, biology, Topoisomerase, Staphylococcal Infections, Anti-Bacterial Agents, chemistry, Mechanism of action, DNA Gyrase, biology.protein, DNA supercoil, Benzimidazoles, Topoisomerase-II Inhibitor, medicine.symptom, Antibacterial activity, DNA
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المؤلفون: Helen Valentine, Maria de la Fuente, Stephen Neidle, Sarah J. Welsh, Andreas G. Schätzlein, Aaron G. Dale, Caterina Lombardo
المصدر: Scientific Reports
مصطلحات موضوعية: Transcriptional Activation, Hypoxia-Inducible Factor 1, Angiogenesis, Blotting, Western, Mice, Nude, Real-Time Polymerase Chain Reaction, Response Elements, Bioinformatics, Article, Immunoenzyme Techniques, Small Molecule Libraries, Mice, Tumor Cells, Cultured, Hypoxia-Inducible Factor Pathway, Animals, Humans, Medicine, RNA, Messenger, Promoter Regions, Genetic, Carcinoma, Renal Cell, Transcription factor, Regulation of gene expression, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Hypoxia-Inducible Factor 1, alpha Subunit, Xenograft Model Antitumor Assays, Cell Hypoxia, Kidney Neoplasms, G-Quadruplexes, Gene Expression Regulation, Neoplastic, Blot, Hypoxia-inducible factors, Cell culture, Carcinogens, Cancer research, Female, business
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المؤلفون: Aaron G. Dale, Duncan J. Maskell, J. Archer, S.F.E. Scholes, H.S. Niesalla, J.D. Slater, A.W. Tucker
المصدر: Journal of virological methods. 158(1-2)
مصطلحات موضوعية: biology, Cell Survival, Tumor Necrosis Factor-alpha, Gene Expression Profiling, Herpesviridae Infections, Respiratory Mucosa, biology.organism_classification, Organ culture, medicine.disease_cause, Virology, Bovine herpesvirus 1, Virus, Herpesviridae, Microbiology, medicine.anatomical_structure, Organ Culture Techniques, Cell culture, Alphaherpesvirinae, medicine, Animals, Cattle, Pathogen, Respiratory tract, Herpesvirus 1, Bovine
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المؤلفون: Carol E. Evered, Stephen D. Jackson, Aaron G. Dale, Florence Goubet, Xiaolan Yu, Tadashi Ishii, Lesley Codrai, Lindsay Bown, Paul Dupree, Karl Morris, Zhinong Zhang, Shinnosuke Kusaba
المصدر: Journal of experimental botany. 58(7)
مصطلحات موضوعية: Physiology, Recombinant Fusion Proteins, Mutant, Arabidopsis, Golgi Apparatus, Plant Science, Root hair, Biology, Plant Roots, Cell wall, chemistry.chemical_compound, Plant Growth Regulators, Auxin, Cell Wall, Cell Adhesion, Cell adhesion, Abscisic acid, Alleles, Cell Size, chemistry.chemical_classification, Arabidopsis Proteins, Glycosyltransferases, Fusion protein, Cell biology, Phenotype, chemistry, Biochemistry, Mutation, Pectins, Gibberellin, Abscisic Acid, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c71bfbf54ba2cfae56391e5c93ff0ba
https://pubmed.ncbi.nlm.nih.gov/17426055
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