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1
المؤلفون: Ted Liefeld, Li Wang, Michael R. Reich, Guoying K. Yu, Felipa A. Mapa, Judit Jané-Valbuena, Giordano Caponigro, Joseph Thibault, Michael F. Berger, Jill Cheng, Kavitha Venkatesan, Kalpana Jagtap, Nicolas Stransky, Nanxin Li, Ingo H. Engels, Lauren Murray, Anupama Reddy, Gad Getz, Dmitriy Sonkin, Barbara L. Weber, Aaron Shipway, Jodi Meltzer, Peter Finan, Todd R. Golub, Jianjun Yu, Adam A. Margolin, Robert C. Onofrio, Peter Aspesi, Michael D. Jones, Kristin G. Ardlie, Scott Mahan, Vivien W. Chan, Jennifer L. Harris, Gregory V. Kryukov, Wendy Winckler, Vic E. Myer, Manway Liu, Pichai Raman, Matthew Meyerson, Jill P. Mesirov, William R. Sellers, Christine D. Wilson, Stacey Gabriel, Joseph Lehar, Michael Morrissey, Robert Schlegel, Jeffrey A. Porter, Supriya Gupta, Emanuele Palescandolo, John Monahan, Charlie Hatton, Levi A. Garraway, Paula Morais, Laura E. MacConaill, Sungjoon Kim, Jordi Barretina, Eva Bric-Furlong, Markus Warmuth, Melanie de Silva, Adam Korejwa, Carrie Sougnez
المصدر: Nature. 565:E5-E6
مصطلحات موضوعية: Multidisciplinary, business.industry, Cancer cell line encyclopedia, Medicine, Addendum, Sensitivity (control systems), Computational biology, business, Anticancer drug, Predictive modelling
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2
المؤلفون: Joseph Thibault, Michael F. Berger, Markus Warmuth, Adam A. Margolin, Laura E. MacConaill, Scott Mahan, Vivien W. Chan, Levi A. Garraway, Vic E. Myer, Christine D. Wilson, Stacey Gabriel, Jill P. Mesirov, Dmitriy Sonkin, Eva Bric-Furlong, Aaron Shipway, Wendy Winckler, Anupama Reddy, Adam Korejwa, Carrie Sougnez, Felipa A. Mapa, Judit Jané-Valbuena, Gad Getz, John Monahan, Peter Aspesi, Kristin G. Ardlie, Barbara L. Weber, Jianjun Yu, Nicolas Stransky, Michael R. Reich, Ted Liefeld, Emanuele Palescandolo, Michael D. Jones, Charlie Hatton, William R. Sellers, Lauren Murray, Melanie de Silva, Paula Morais, Michael Morrissey, Robert Schlegel, Jordi Barretina, Joseph Lehar, Jeffrey A. Porter, Supriya Gupta, Nanxin Li, Robert C. Onofrio, Gregory V. Kryukov, Pichai Raman, Matthew Meyerson, Jennifer L. Harris, Guoying K. Yu, Jill Cheng, Kavitha Venkatesan, Kalpana Jagtap, Jodi Meltzer, Peter Finan, Sungjoon Kim, Li Wang, Ingo H. Engels, Giordano Caponigro, Todd R. Golub, Manway Liu
المصدر: Nature
مصطلحات موضوعية: Encyclopedias as Topic, Databases, Factual, Topoisomerase Inhibitors, medicine.drug_class, Plasma Cells, Antineoplastic Agents, Genomics, Computational biology, Biology, Bioinformatics, Models, Biological, Article, Receptor, IGF Type 1, Cell Line, Tumor, Neoplasms, medicine, Chromosomes, Human, Humans, Cell Lineage, Precision Medicine, Mitogen-Activated Protein Kinase Kinases, Clinical Trials as Topic, Multidisciplinary, Massive parallel sequencing, Genome, Human, Drug discovery, business.industry, Gene Expression Profiling, Cancer, Sequence Analysis, DNA, medicine.disease, Human genetics, Gene Expression Regulation, Neoplastic, Gene expression profiling, Genes, ras, Receptors, Aryl Hydrocarbon, Pharmacogenetics, Personalized medicine, Drug Screening Assays, Antitumor, business, Topoisomerase inhibitor
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3
المؤلفون: Jennifer L. Harris, David C. Tully, Michael Hornsby, Badry Bursulaya, Henry Danahay, Glen Spraggon, Aaron Shipway, Scott A. Lesley
المصدر: Protein Science. 18:1081-1094
مصطلحات موضوعية: Camostat, Proteases, Gabexate, Cations, Divalent, Protein Conformation, Stereochemistry, medicine.medical_treatment, Crystallography, X-Ray, Guanidines, Biochemistry, Article, Substrate Specificity, Divalent, chemistry.chemical_compound, Aprotinin, Protein structure, Catalytic Domain, medicine, Chymotrypsin, Humans, Protease Inhibitors, Molecular Biology, chemistry.chemical_classification, Serine protease, Protease, biology, Serine Endopeptidases, Active site, Esters, Sodium ion transport, chemistry, biology.protein, Calcium, Sequence Alignment
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4
المؤلفون: Henry Danahay, Michael J. Roberts, Badry Bursulaya, H. Michael Petrassi, Vidal Agnes, Arnab K. Chatterjee, Jennifer A. Williams, Andrew M. Schumacher, David C. Tully, Aaron Shipway, Reynand Pacoma, Glen Spraggon, Jennifer L. Harris
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:5895-5899
مصطلحات موضوعية: Serine Proteinase Inhibitors, Molecular model, Protein Conformation, Peptidomimetic, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Drug Discovery, medicine, Combinatorial Chemistry Techniques, Molecular Biology, chemistry.chemical_classification, Protease, Molecular Structure, biology, Molecular Mimicry, Serine Endopeptidases, Organic Chemistry, PRSS8, Active site, Small molecule, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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5
المؤلفون: Matthew Bogyo, Zbynek Bozdech, Chao-lin Liu, Jennifer L. Harris, Bradley J. Backes, Ching C. Wang, Aaron Shipway
المصدر: Journal of Biological Chemistry. 278:15800-15808
مصطلحات موضوعية: Proteasome Endopeptidase Complex, Protein subunit, Molecular Sequence Data, Trypanosoma brucei brucei, Protozoan Proteins, Biology, Trypanosoma brucei, Biochemistry, Substrate Specificity, Multienzyme Complexes, Catalytic Domain, parasitic diseases, Animals, Amino Acid Sequence, Binding site, Molecular Biology, Peptide sequence, Binding Sites, Affinity labeling, Tetrapeptide, Cell Biology, Proteasome complex, biology.organism_classification, Cysteine Endopeptidases, Protein Subunits, Proteasome
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbab464071a48bc4116e70a2bf64f38
https://doi.org/10.1074/jbc.m300195200 -
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المؤلفون: Jennifer A. Williams, Bradley J. Backes, Henry Danahay, Jennifer L. Harris, David C. Tully, Aaron Shipway
المصدر: Biochemical and biophysical research communications. 324(2)
مصطلحات موضوعية: Anions, DNA, Complementary, Insecta, Arginine, medicine.medical_treatment, Lysine, Blotting, Western, Biophysics, Biochemistry, Sodium Channels, Cell Line, Substrate Specificity, Serine, Peptide Library, Cations, medicine, Animals, Humans, Histidine, Cloning, Molecular, Epithelial Sodium Channels, Molecular Biology, Gene Library, chemistry.chemical_classification, Alanine, Ions, Protease, Binding Sites, Models, Genetic, PRSS8, Serine Endopeptidases, Cell Biology, Hydrogen-Ion Concentration, Recombinant Proteins, Amino acid, Protein Structure, Tertiary, Kinetics, Zinc, chemistry, Metals, Electrophoresis, Polyacrylamide Gel, Peptide Hydrolases, Protein Binding
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7
المؤلفون: Bradley J. Backes, Nicolas Winssinger, François Debaene, Teresa Chen, Jennifer L. Harris, Keith W. Burdick, Farouk Shakib, Jun Li, L. Gough, Daniel E. Mason, Amir M. Ghaemmaghami, Gino Van Heeke, Aaron Shipway
المصدر: Chemistry & Biology, Vol. 11, No 10 (2004) pp. 1361-1372
مصطلحات موضوعية: House dust mite, chemistry.chemical_classification, Pharmacology, Proteases, Peptide nucleic acid, biology, Tetrapeptide, Clinical Biochemistry, General Medicine, biology.organism_classification, Molecular biology, Biochemistry, respiratory tract diseases, Serine, chemistry.chemical_compound, Enzyme, chemistry, Affinity chromatography, Drug Discovery, Molecular Medicine, Molecular Biology, Cysteine
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8
المؤلفون: Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J.Wilson, Joseph Lehár, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy, Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jané-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guoying K. Yu, Jianjun Yu, Peter Aspesi, Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura MacConaill, Wendy Winckler, Michael Reich, Nanxin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Meyerson, Todd R. Golub, Michael P. Morrissey, William R. Sellers, Robert Schlegel, Levi A. Garraway
المصدر: Nature. 492:290-290
مصطلحات موضوعية: Multidisciplinary
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9
المؤلفون: Vic Meyer, Jodi Meltzer, Lauren Murray, William R. Sellers, Giordano Caponigro, Robert Schlegel, Laura E. MacConaill, Peter Finan, Jennifer L. Harris, Sungjoon Kim, John Che, Dmitriy Sonkin, Scott Mahan, Michael D. Jones, Supriya Gupta, Pichai Raman, Nanxin Li, Christine D. Wilson, Jared L. Nedzel, Nicolas Stransky, Kavitha Venkhatesan, Adam Callahan, Kristin G. Ardlie, Jill P. Mesirov, Ted Liefeld, Levi A. Garraway, Matthew Meyerson, Adam Margolin, Gad Getz, Michael R. Reich, Barbara L. Weber, Lili Niu, Reid M. Pinchback, Todd R. Golub, Carrie Sougnez, Robert C. Onofrio, Andrew I. Su, Aaron Shipway, Wendy Winckler, Ingo H. Engels, Gregory V. Kryukov, Joseph Thibault, Michael F. Berger, Michael Morrissey, Markus Warmuth, Charlie Hatton, Emanuele Palescandolo, Paula Morais, Jordi Barretina, John Monahan
المصدر: Cancer Research. 71:5455-5455
مصطلحات موضوعية: Cancer Research, Massive parallel sequencing, biology, business.industry, Cancer cell line encyclopedia, Topoisomerase, Cancer Model, Genomics, Computational biology, Clinical trial, Oncology, Cancer Medicine, Potential biomarkers, biology.protein, Medicine, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::921107a14f00b4f9f5d0776d7a220d7f
https://doi.org/10.1158/1538-7445.am2011-5455 -
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المؤلفون: Yan Ding, Ted Liefeld, Giordano Caponigro, Michael Morrissey, Charlie Hatton, Carrie Sougnez, William R. Sellers, Adam Callahan, Robert Schlegel, John Che, Andrew I. Su, Stacey Gabriel, Nanxin Li, Ingo H. Engels, Jessica Slind, Todd R. Golub, Jordi Barretina, Aaron Shipway, Wendy Winckler, Joseph Thibault, Michael F. Berger, Christine D. Wilson, Nicolas Stransky, Levi A. Garraway, Lili Niu, Cory M. Johannessen, John Monahan, Supriya Gupta, Gad Getz, Laura E. MacConaill, Barbara L. Weber, Kavitha Venkhatesan, Paula Morais, Jennifer L. Harris, Scott Mahan, Sarah M. Kehoe, Markus Warmuth, Vic Meyer, Dmitriy Sonkin, Sungjoon Kim, Michael R. Reich, Kristin G. Ardlie, Venkateshwar A. Reddy, Liuda Ziaugra, Jodi Meltzer, Peter Finan, Michael D. Jones, Pichai Raman, Matthew Meyerson, Robert C. Onofrio
المصدر: Cancer Research. 70:2620-2620
مصطلحات موضوعية: Clinical trial, Cancer Research, Massive parallel sequencing, Oncology, biology, Cancer cell line encyclopedia, Cancer Model, biology.protein, Genomics, Bioinformatics, Gene, Receptor tyrosine kinase, EGFR inhibitors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0c61005a5237f2c9663d2d5dce96b7e3
https://doi.org/10.1158/1538-7445.am10-2620