المؤلفون: Maureen A. Kane, Jordan D. Pritts, Abdulafeez A. Oluyadi, Angela Wilks, Sarah L. J. Michel, Geoffrey D. Shimberg, Weiliang Huang

المصدر: Biochemistry

مصطلحات موضوعية: Poly U, Zinc finger, Binding Sites, Polyadenylation, Chemistry, Cleavage And Polyadenylation Specificity Factor, RNA, Zinc Fingers, Cleavage and polyadenylation specificity factor, Biochemistry, Article, Cell biology, RNA Precursors, Animals, Cattle, RNA, Messenger, Protein Binding, Pre mrna processing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7c09f9043b8c1a0bbe388730ae1026
https://doi.org/10.1021/acs.biochem.0c00940

المؤلفون: Sarah L. J. Michel, Gerald M. Wilson, Heather M. Neu, Andria V. Rodrigues, Timothy L. Stemmler, Geoffrey D. Shimberg, Kanisha Sureschandra, Shanchari Ghosh, Abdulafeez A. Oluyadi, Beth E. Zucconi, Jamie L. Michalek

المصدر: Proceedings of the National Academy of Sciences. 113:4700-4705

مصطلحات موضوعية: 0301 basic medicine, RNA 3' Polyadenylation Signals, Polyadenylation, Iron, Cleavage and polyadenylation specificity factor, 03 medical and health sciences, Humans, Computer Simulation, RNA, Messenger, Binding site, mRNA Cleavage and Polyadenylation Factors, Zinc finger, Binding Sites, Multidisciplinary, Chemistry, Cleavage And Polyadenylation Specificity Factor, RNA, Cooperative binding, Biological Sciences, Ligand (biochemistry), 030104 developmental biology, Models, Chemical, Biochemistry, Sulfur, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8e772f59350da8cd99a1c5eb3cbf78
https://doi.org/10.1073/pnas.1517620113

المؤلفون: Jordan D. Pritts, Abdulafeez A. Oluyadi, Patrick L. Wintrode, Daniel Deredge, Sarah L. J. Michel

المصدر: Biophysical Journal. 116:503a

مصطلحات موضوعية: Mechanism (biology), Chemistry, Biophysics, Rna regulation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1c8443edaf6099f600771ba3df0a9298
https://doi.org/10.1016/j.bpj.2018.11.2712

المؤلفون: Shuhua Ma, Clare N. Muhoro, Abdulafeez A. Oluyadi

المصدر: Organometallics. 32:70-78

مصطلحات موضوعية: Aryl, Organic Chemistry, Conjugated system, Medicinal chemistry, Catalysis, Inorganic Chemistry, Benzaldehyde, chemistry.chemical_compound, Hydroboration, chemistry, Benzophenone, Organic chemistry, Physical and Theoretical Chemistry, Catecholborane, Bond cleavage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::acb88cce4f5da8b5e61834e59e9ce560
https://doi.org/10.1021/om300828m

المؤلفون: Sarah L. J. Michel, Angelique N. Besold, Abdulafeez A. Oluyadi

المصدر: Inorganic chemistry. 52(8)

مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, Nerve Tissue Proteins, DNA-binding protein, Article, Inorganic Chemistry, chemistry.chemical_compound, Animals, Histidine, Amino Acid Sequence, Physical and Theoretical Chemistry, Binding site, education, Peptide sequence, Zinc finger, education.field_of_study, Binding Sites, Zinc Fingers, Cobalt, DNA, Zinc finger nuclease, Rats, DNA-Binding Proteins, Zinc, Biochemistry, chemistry, Metals, Mutation, Trans-Activators, Peptides, Myelin transcription factor 1, Sequence Alignment, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299386034f685d942854e4220a1a823a
https://pubmed.ncbi.nlm.nih.gov/23521535

المؤلفون: Glenthøj A; Department of Haematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. Electronic address: andreas.glenthoej@regionh.dk., van Beers EJ; Benign Hematology Center, Van Creveldkliniek, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands., Al-Samkari H; Division of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Viprakasit V; Siriraj Hospital, Mahidol University, Bangkok, Thailand., Kuo KHM; Division of Hematology, University of Toronto, Toronto, ON, Canada., Galactéros F; Unité des Maladies Génétiques du Globule Rouge, CHU Henri Mondor, Créteil, France., Chonat S; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA, USA., Porter J; Department of Haematology, University College London Cancer Institute, London, UK., Zagadailov E; Agios Pharmaceuticals, Cambridge, MA, USA., Xu R; Agios Pharmaceuticals, Cambridge, MA, USA., Oluyadi A; Agios Pharmaceuticals, Cambridge, MA, USA., Hawkins P; Agios Pharmaceuticals, Cambridge, MA, USA., Gheuens S; Agios Pharmaceuticals, Cambridge, MA, USA., Beynon V; Agios Pharmaceuticals, Cambridge, MA, USA., Barcellini W; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

مؤلفون مشاركون: ACTIVATE-T investigators

المصدر: The Lancet. Haematology [Lancet Haematol] 2022 Oct; Vol. 9 (10), pp. e724-e732. Date of Electronic Publication: 2022 Aug 18.

نوع المنشور: Clinical Trial, Phase III; Journal Article; Multicenter Study

بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101643584 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3026 (Electronic) Linking ISSN: 23523026 NLM ISO Abbreviation: Lancet Haematol Subsets: MEDLINE

مواضيع طبية MeSH: Hemoglobins* , Pyruvate Kinase*/deficiency, Adolescent ; Adult ; Alanine Transaminase ; Anemia, Hemolytic, Congenital Nonspherocytic ; Aspartate Aminotransferases ; Female ; Humans ; Male ; Pharmaceutical Preparations ; Piperazines ; Pyruvate Metabolism, Inborn Errors ; Quinolines ; Treatment Outcome ; Triglycerides

SCR Disease Name: Pyruvate Kinase Deficiency of Red Cells