المؤلفون: Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt. Electronic address: hanangaber@azhar.edu.eg., Mansour RE; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., Farghaly TA; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia. Electronic address: tamohamed@uqu.edu.sa., El-Sehrawi HM; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 May; Vol. 146, pp. 107284. Date of Electronic Publication: 2024 Mar 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Hydantoins*/pharmacology , Leukemia*/drug therapy, Humans ; Cell Line, Tumor ; Cell Proliferation ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylase Inhibitors/chemistry ; Histone Deacetylases/metabolism ; Histones/metabolism ; Molecular Docking Simulation ; Structure-Activity Relationship ; Zinc/metabolism ; Benzimidazoles/chemistry ; Benzimidazoles/pharmacology

المؤلفون: Farghaly TA; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Alqurashi RM; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Masaret GS; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

المصدر: Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2024; Vol. 24 (9), pp. 920-982.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101094212 Publication Model: Print Cited Medium: Internet ISSN: 1875-5607 (Electronic) Linking ISSN: 13895575 NLM ISO Abbreviation: Mini Rev Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Quinoxalines*/chemistry , Quinoxalines*/pharmacology , Quinoxalines*/chemical synthesis, Humans ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antioxidants/pharmacology ; Antioxidants/chemical synthesis ; Antioxidants/chemistry ; Animals ; Molecular Structure ; Antiviral Agents/pharmacology ; Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/chemistry

المؤلفون: Farghaly TA; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukaramah, Saudi Arabia., Alosaimy AM; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukaramah, Saudi Arabia., Al-Qurashi NT; Department of Basic Science, University College in Adam, Umm Al-Qura University, Makkah Almukkarramah, Saudi Arabia., Masaret GS; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukaramah, Saudi Arabia., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

المصدر: Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2024; Vol. 24 (8), pp. 793-843.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101094212 Publication Model: Print Cited Medium: Internet ISSN: 1875-5607 (Electronic) Linking ISSN: 13895575 NLM ISO Abbreviation: Mini Rev Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Amines*/chemistry , Amines*/pharmacology , Amines*/chemical synthesis, Heterocyclic Compounds/chemistry ; Heterocyclic Compounds/pharmacology ; Heterocyclic Compounds/chemical synthesis ; Humans ; Molecular Structure

المؤلفون: Farghaly TA; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Masaret GS; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City, Cairo, Egypt.

المصدر: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2023 Dec; Vol. 33 (12), pp. 875-899. Date of Electronic Publication: 2024 Jan 15.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design* , Patents as Topic* , Tropanes*/pharmacology, Humans ; Atropine ; Drug Discovery

المؤلفون: Mansour RE; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., El-Sehrawi HM; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Jun; Vol. 356 (6), pp. e2200433. Date of Electronic Publication: 2023 Mar 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Leukemia*, Humans ; Structure-Activity Relationship ; Molecular Docking Simulation ; Histone Deacetylase Inhibitors ; Cell Line, Tumor ; Hydroxamic Acids/pharmacology ; Vorinostat/pharmacology ; Barbiturates/pharmacology ; Benzimidazoles/pharmacology ; Drug Design ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Histone Deacetylase 6

المؤلفون: Gaber AA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt., Sobhy M; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt., Turky A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., Al-Karmalawy AA; Department of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, Egypt., Elhendawy MA; Department of Chemistry and Biochemistry, University of Mississippi, MS, USA.; Department of Agriculture Chemistry, Faculty of Agriculture, Damietta University, Damietta, Egypt., Radwan MM; National Center for Natural Products Research, University of Mississippi, University, MS, USA.; Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia., Ibrahim IM; Biophysics Department, Faculty of Science, Cairo University, Cairo, Egypt., Elzahabi HSA; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., Eissa IH; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.

المصدر: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2283-2303.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Lung Neoplasms*/drug therapy, Cell Line, Tumor ; Cell Proliferation ; Drug Screening Assays, Antitumor ; ErbB Receptors/metabolism ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Pyrimidines/pharmacology ; Structure-Activity Relationship

المؤلفون: Khormi AY; Department of Chemistry, Faculty of Science, King Khalid University Abha Saudi Arabia., Farghaly TA; Department of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt.; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University Makkah Almukarramah Saudi Arabia., Bayazeed A; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University Makkah Almukarramah Saudi Arabia., Al-Ghamdi YO; Department of Chemistry, College of Science Al-zulfi, Majmaah University Al-Majmaah 11952 Saudi Arabia., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University Cairo Egypt hanangaber@azhar.edu.eg., Shaaban MR; Department of Chemistry, Faculty of Science, Cairo University Giza 12613 Egypt.

المصدر: RSC advances [RSC Adv] 2022 Sep 27; Vol. 12 (42), pp. 27355-27369. Date of Electronic Publication: 2022 Sep 27 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE

المؤلفون: Farghaly TA; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt.; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Al-Hasani WA; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi Arabia., Abdulwahab HG; Department of Pharmaceutical Medicinal Chemistry and Drug Design, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

المصدر: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2021 Nov; Vol. 31 (11), pp. 989-1007. Date of Electronic Publication: 2021 Jun 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

مواضيع طبية MeSH: Angiogenesis Inhibitors/*pharmacology , Neovascularization, Pathologic/*drug therapy , Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors, Angiogenesis Inhibitors/adverse effects ; Animals ; Humans ; Neoplasms/blood supply ; Neoplasms/drug therapy ; Neovascularization, Pathologic/pathology ; Patents as Topic ; Signal Transduction/drug effects ; Vascular Endothelial Growth Factor A/metabolism

المؤلفون: Mahmoud HK; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Farghaly TA; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukkarramah, Saudi Arabia. Electronic address: thoraya-f@hotmail.com., Abdulwahab HG; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., Al-Qurashi NT; Department of Basic Science, University College in Adam, Umm Al-Qura University, Makkah Almukkarramah, Saudi Arabia., Shaaban MR; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt; Department of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Almukkarramah, Saudi Arabia.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2020 Dec 15; Vol. 208, pp. 112752. Date of Electronic Publication: 2020 Aug 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Kidney Neoplasms/*drug therapy , Oxindoles/*pharmacology , Protein Kinase Inhibitors/*pharmacology , Thiazoles/*pharmacology , Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/metabolism ; Binding Sites ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Oxindoles/chemical synthesis ; Oxindoles/metabolism ; Protein Binding ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/metabolism ; Sunitinib/chemistry ; Thiazoles/chemical synthesis ; Thiazoles/metabolism ; Vascular Endothelial Growth Factor Receptor-2/chemistry ; Vascular Endothelial Growth Factor Receptor-2/metabolism

المؤلفون: Abdulwahab HG; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt. Electronic address: hanangaber@azhar.edu.eg., Harras MF; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., El Menofy NG; Department of Microbiology and Immunology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt., Hegab AM; Developmental Pharmacology Department, National Organization for Drug Control and Research, Giza, Egypt., Essa BM; Radioactive Isotopes and Generator Department, Hot Laboratories Center, Egyptian Atomic Energy Authority (EAEA), P.O. Box 13759, Cairo, Egypt., Selim AA; Labeled Compounds Department, Hot Labs Center, Egyptian Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt., Sakr TM; Radioactive Isotopes and Generator Department, Hot Laboratories Center, Egyptian Atomic Energy Authority (EAEA), P.O. Box 13759, Cairo, Egypt., El-Zahabi HSA; Pharmaceutical Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Dec 01; Vol. 28 (23), pp. 115759. Date of Electronic Publication: 2020 Sep 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Anti-Bacterial Agents/*chemical synthesis , Enzyme Inhibitors/*chemistry , Thiobarbiturates/*chemistry , Urease/*antagonists & inhibitors, Animals ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; Binding Sites ; Catalytic Domain ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/pharmacology ; Hydrogen-Ion Concentration ; Isotope Labeling ; Klebsiella pneumoniae/drug effects ; Male ; Mice ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Organotechnetium Compounds/chemistry ; Proteus vulgaris/drug effects ; Structure-Activity Relationship ; Thiobarbiturates/metabolism ; Thiobarbiturates/pharmacology ; Thiourea/analogs & derivatives ; Thiourea/metabolism ; Thiourea/pharmacology ; Tissue Distribution ; Urease/metabolism