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المؤلفون: Abo-Elmagd MI; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Hassan RM; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Aboutabl ME; Medicinal and Pharmaceutical Chemistry Department, Pharmacology Group, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Amin KM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt., El-Azzouny AA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. Electronic address: mnaboulenein@yahoo.com.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Sep; Vol. 150, pp. 107577. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Triazoles*/chemistry , Triazoles*/pharmacology , Triazoles*/chemical synthesis , Drug Design* , Cyclooxygenase 1*/metabolism , Cyclooxygenase 2*/metabolism , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Anti-Inflammatory Agents, Non-Steroidal*/chemical synthesis , Anti-Inflammatory Agents, Non-Steroidal*/chemistry , Edema*/drug therapy , Edema*/chemically induced, Animals ; Structure-Activity Relationship ; Rats ; Molecular Structure ; Tetrahydroisoquinolines/pharmacology ; Tetrahydroisoquinolines/chemistry ; Tetrahydroisoquinolines/chemical synthesis ; Cyclooxygenase Inhibitors/pharmacology ; Cyclooxygenase Inhibitors/chemical synthesis ; Cyclooxygenase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Cyclooxygenase 2 Inhibitors/pharmacology ; Cyclooxygenase 2 Inhibitors/chemical synthesis ; Cyclooxygenase 2 Inhibitors/chemistry ; Molecular Docking Simulation ; Male ; Carrageenan ; Rats, Wistar ; Humans ; Stomach Ulcer/chemically induced ; Stomach Ulcer/drug therapy

المؤلفون: Hassan RM; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. rashahassan_pharma@yahoo.ca., Yehia H; Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., El-Behairy MF; Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, 32897, Sadat City, Egypt., El-Azzouny AA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. mnaboulenein@yahoo.com.

المصدر: Molecular diversity [Mol Divers] 2024 Apr 24. Date of Electronic Publication: 2024 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

المؤلفون: Hassan RM; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. Electronic address: rashahassan_pharma@yahoo.ca., Abd El-Maksoud MS; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Ghannam IAY; Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Dokki, Cairo, 12622, Egypt., El-Azzouny AA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. Electronic address: mnaboulenein@yahoo.com.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2023 Dec 15; Vol. 262, pp. 115867. Date of Electronic Publication: 2023 Oct 11.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Bacterial Infections*, Humans ; Gram-Negative Bacteria ; Gram-Positive Bacteria ; Biofilms ; Bacteria ; Quorum Sensing

المؤلفون: El-Azzouny AMAE; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Giza, Egypt., Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Giza, Egypt., Hamissa MF; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Giza, Egypt.; Department of Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czech Republic.; Department of Biomolecular Spectroscopy, Institute of Organic Chemistry and Biochemistry, Academy of Sciences, Prague, Czech Republic.

المصدر: Drug development research [Drug Dev Res] 2020 Nov; Vol. 81 (7), pp. 786-802. Date of Electronic Publication: 2020 May 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

مواضيع طبية MeSH: Quinolines/*chemistry , Quinolines/*pharmacology, Animals ; Humans ; Structure-Activity Relationship

المؤلفون: Aboutabl ME; Medicinal and Pharmaceutical Chemistry Department (Pharmacology Group), Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Hassan RM; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., El-Azzouny AA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. Electronic address: mnaboulenein@yahoo.com., Abd-Allah WH; Pharmaceutical Chemistry Department, College of Pharmaceutical Science and Drug Manufacturing, Misr University for Science & Technology, P.O. 77, 6th of October City, Giza, Egypt.

المصدر: Bioorganic chemistry [Bioorg Chem] 2020 Jan; Vol. 94, pp. 103473. Date of Electronic Publication: 2019 Nov 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Anticonvulsants/*pharmacology , Hydantoins/*pharmacology , Seizures/*drug therapy, Animals ; Anticonvulsants/chemical synthesis ; Anticonvulsants/chemistry ; Dose-Response Relationship, Drug ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Hydantoins/chemical synthesis ; Hydantoins/chemistry ; Male ; Mice ; Models, Molecular ; Molecular Structure ; Pentylenetetrazole ; Seizures/chemically induced ; Structure-Activity Relationship

المؤلفون: Hassan RM; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Abd-Allah WH; Pharmaceutical Chemistry Department, College of Pharmaceutical Science and Drug Manufacturing, Misr University for Science and Technology, P.O. 77, 6th of October City, Giza, Egypt., Salman AM; Medicinal and Pharmaceutical Chemistry Department, Pharmacology Group, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., El-Azzouny AA; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt., Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), P.O. 12622, Dokki, Giza, Egypt. Electronic address: mnaboulenein@yahoo.com.

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2019 Nov 01; Vol. 139, pp. 105045. Date of Electronic Publication: 2019 Aug 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Dioxins*/chemistry , Dioxins*/pharmacology , Dioxoles*/chemistry , Dioxoles*/pharmacology, Apoptosis/drug effects ; Cell Line ; Cell Survival/drug effects ; Drug Design ; Humans ; Molecular Docking Simulation ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Tubulin Modulators/chemistry ; Tubulin Modulators/pharmacology ; Tumor Suppressor Protein p53/metabolism

المؤلفون: Aboul-Enein MN; Department of Medicinal and Pharmaceutical Chemistry, Medicinal Chemistry Group, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Dokki, Giza, Egypt., El-Azzouny AA; Department of Medicinal and Pharmaceutical Chemistry, Medicinal Chemistry Group, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Dokki, Giza, Egypt., Amin KM; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Cairo University, Cairo, Egypt., Aboutabl ME; Department of Medicinal and Pharmaceutical Chemistry, Pharmacology Group, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Dokki, Giza, Egypt., Abo-Elmagd MI; Department of Medicinal and Pharmaceutical Chemistry, Medicinal Chemistry Group, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), Dokki, Giza, Egypt.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2018 Dec; Vol. 351 (12), pp. e1800269. Date of Electronic Publication: 2018 Nov 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Anticonvulsants/*chemical synthesis , Anticonvulsants/*chemistry , Seizures/*drug therapy, Animals ; Anticonvulsants/pharmacology ; Anticonvulsants/toxicity ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Drug-Related Side Effects and Adverse Reactions/etiology ; Mice ; Models, Molecular ; Molecular Structure ; Neurotoxicity Syndromes/etiology ; Pentylenetetrazole/administration & dosage

المؤلفون: Aboul-Enein HY; Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), 12622 Dokki, Giza 12622, Egypt., Aboul-Enein MN; Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), 12622 Dokki, Giza 12622, Egypt., El-Azzouny AA; Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), 12622 Dokki, Giza 12622, Egypt., Saleh OA; Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), 12622 Dokki, Giza 12622, Egypt., Hassan RM; Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (ID: 60014618), 12622 Dokki, Giza 12622, Egypt., Amin KM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.

المصدر: Journal of chromatographic science [J Chromatogr Sci] 2018 Feb 01; Vol. 56 (2), pp. 160-165.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited Medium: Internet ISSN: 1945-239X (Electronic) Linking ISSN: 00219665 NLM ISO Abbreviation: J Chromatogr Sci Subsets: MEDLINE

مواضيع طبية MeSH: Spiro Compounds*/analysis , Spiro Compounds*/chemistry , Spiro Compounds*/isolation & purification, Amylose/*chemistry , Chromatography, High Pressure Liquid/*methods, Stereoisomerism

المؤلفون: Aboul-Enein MN; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Giza, Egypt., El-Azzouny AM; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Giza, Egypt., Ragab FA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Hamissa MF; Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Giza, Egypt.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2017 Apr; Vol. 350 (3-4). Date of Electronic Publication: 2017 Mar 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Drug Design*, Antineoplastic Agents/*pharmacology , Protein Kinase Inhibitors/*pharmacology , Vascular Endothelial Growth Factor Receptor-2/*antagonists & inhibitors, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; MCF-7 Cells ; Models, Molecular ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2/metabolism